Analysis of a simulated moving bed operation for three-fraction separations (3F-SMB)

Industrial and Engineering Chemistry Research

Volumn 43, Issue 19, 2004, Pages 6157-6167

  Paredes, Galatea ^a   Abel, Stefanie ^a   Mazzotti, Marco ^a   Morbidelli, Massimo ^a   Stadler, Joachim ^a,b  

^a ETH ZURICH   (Switzerland)

^b Amersham Biosciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; CLEANING; COMPUTER SIMULATION; IMPURITIES; SEPARATION;

CLEANING-IN-PLACE (CIP); NUCLEOSIDES; THREE-FRACTION SIMULATED MOVING BED (3F-SMB);

CHEMICAL ENGINEERING;

DEOXYADENOSINE; DEOXYCYTIDINE; DEOXYGUANOSINE; NUCLEOSIDE; THYMIDINE;

MOVING BED REGIME; SEPARATION;

ARTICLE; CHROMATOGRAPHY; FLOW RATE; MODEL; SEPARATION TECHNIQUE; SIMULATION; VALIDATION PROCESS;

EID: 4444266642     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie0498293     Document Type: Article

References (19)

1. Ruthven, D. M.; Ching, C. B. Chem. Eng. Sci. 1989, 44, 1011-1038.
2. Nicoud, R.-M. Pharm. Technol. Eur. 1999, 11, 28-34.
3. Juza, M.; Mazzotti, M.; Morbidelli, M. Trends Biotechnol. 2000, 18, 108-118.
4. Schulte, M.; Strube, J. J. Chromatogr. A 2001, 906, 399-416.
5. Nicolaos, A.; Muhr, L.; Gotteland, P.; Nicoud, R. M.; Bailly, M. J. Chromatogr. A 2001, 908, 71-86.
6. Nicolaos, A.; Muhr, L.; Gotteland, P.; Nicoud, R. M.; Bailly, M. J. Chromatogr. A 2001, 908, 87-109.
7. Beste, A.; Arlt, W. Chem. Eng. Technol. 2002, 25, 956-962.
8. Wooley, R.; Ma, Z.; Wang, N.-H. L. Ind. Eng. Chem. Res. 1998, 37, 3699-3709.
9. Wankat, P. C. Ind. Eng. Chem. Res. 2001, 40, 6185-6193.
10. Kim, K. J.; Zang, Y.; Wankat, P. C. Ind. Eng. Chem. Res. 2003, 42, 4849-4860.
11. Hotier, G.; Toussaint, J. M.; Terneuil, G.; Lonchamp, D. U.S. Patent 5,093,004A, 1992.
12. Voigt, U.; Kinkel, J.; Hempel, R.; Nicoud, R. M. U.S. Patent 6,306,306B1, 2001.
13. Abel, S.; Bäbler, M.; Arpagaus, C.; Mazzotti, M.; Stadler, J. J. Chromatogr. A 2004, 1043, 201-210.
14. Mazzotti, M.; Storti, G.; Morbidelli, M. J. Chromatogr. A 1997, 769, 3-24.
15. Migliorini, C.; Mazzotti, M.; Morbidelli, M. AIChE J. 1999, 45, 1411-1422.
16. Migliorini, C.; Mazzotti, M.; Morbidelli, M. J. Chromatogr. A 1998, 827, 161-174.
17. Migliorini, C.; Gentilini, A.; Mazzotti, M.; Morbidelli, M. Ind. Eng. Chem. Res. 1999, 38, 2400-2410.
18. Migliorini, C.; Mazzotti, M.; Morbidelli, M. Sep. Purif. Technol. 2000, 20, 79-96.
19. Zhong, G.; Guiochon, G. Chem. Eng. Sci. 1997, 53, 1121-1130.