Depletion of the Shwachman-Diamond syndrome gene product, SBDS, leads to growth inhibition and increased expression of OPG and VEGF-A

Blood Cells, Molecules, and Diseases

Volumn 42, Issue 1, 2009, Pages 85-91

  Nihrane, Abdallah ^a,b   Sezgin, Gulay ^a,b   Dsilva, Sehba ^a,b   Dellorusso, Paul ^a,b   Yamamoto, Kazuhiko ^a,b   Ellis, Steven R ^c   Liu, Johnson M ^a,b  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b SCHNEIDER CHILDREN'S HOSPITAL   (United States)

^c University of Louisville School of Medicine   (United States)

Author keywords

Angiogenesis; Apoptosis; Growth inhibition; Osteoprotegerin; Shwachman Diamond syndrome; siRNA; Skeletal development; VEGF A

Indexed keywords

GENE PRODUCT; OSTEOPROTEGERIN; VASCULOTROPIN A;

APOPTOSIS; ARTICLE; CELL GROWTH; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSFECTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SHWACHMAN SYNDROME;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; MICE; NIH 3T3 CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOPROTEGERIN; PROTEINS; RNA, SMALL INTERFERING; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 57949098126     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2008.09.004     Document Type: Article

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