Synthesis of 6-O-methotrexylhyaluronan as a drug delivery system

Carbohydrate Research

Volumn 344, Issue 1, 2009, Pages 91-97

  Sorbi, Claudia ^a   Bergamin, Massimo ^a   Bosi, Susanna ^a   Dinon, Francesca ^a   Aroulmoji, Vincent ^b   Khan, Riaz ^b   Murano, Erminio ^a   Norbedo, Stefano ^a  

^a Eurand SpA   (Italy)

^b Protos Research Institute   (Italy)

Author keywords

Drug delivery system; Hyaluronan conjugate; Methotrexate

Indexed keywords

ANTITUMOR DRUGS; DRUG DELIVERY SYSTEM; HYALURONAN CONJUGATE; METHOTREXATE; MIXED ESTERS; NMR SPECTROSCOPIES; ORGANIC CARBOXYLATES;

CARBOXYLATION; ESTERS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS (CHEMICAL);

DRUG DELIVERY;

6 CHLORO 6 DEOXY 6 O METHOTREXYLHYALURONAN; 6 O ACETYL 6 O METHOTREXYLHYALURONAN; 6 O BUTYRYLL 6 O METHOTREXYLHYALURONAN; 6 O METHOTREXYLHYALURONAN; HALOGEN; HYALURONIC ACID; METHOTREXATE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; DRUG SYNTHESIS; HALOGENATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

DRUG CARRIERS; HYALURONIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; METHOTREXATE; MOLECULAR STRUCTURE;

EID: 57749203812     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carres.2008.09.021     Document Type: Article

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