-
1
-
-
0033006172
-
A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
-
Gewirtz D.A. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem. Pharmacol. 57 (1999) 727-741
-
(1999)
Biochem. Pharmacol.
, vol.57
, pp. 727-741
-
-
Gewirtz, D.A.1
-
2
-
-
2642566088
-
Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
-
Minotti G., Menna P., Salvatorelli E., Cairo G., and Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol. Rev. 56 (2004) 185-229
-
(2004)
Pharmacol. Rev.
, vol.56
, pp. 185-229
-
-
Minotti, G.1
Menna, P.2
Salvatorelli, E.3
Cairo, G.4
Gianni, L.5
-
3
-
-
0032563825
-
Doxorubicin-induced cardiomyopathy
-
Singal P.K., and Iliskovic N. Doxorubicin-induced cardiomyopathy. N. Engl. J. Med. 339 (1998) 900-905
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 900-905
-
-
Singal, P.K.1
Iliskovic, N.2
-
4
-
-
0036561332
-
Novel extranuclear-targeted anthracyclines override the antiapoptotic functions of Bcl-2 and target protein kinase C pathways to induce apoptosis
-
Barrett C.M., Lewis F.L., Roaten J.B., Sweatman T.W., Israel M., Cleveland J.L., and Lothstein L. Novel extranuclear-targeted anthracyclines override the antiapoptotic functions of Bcl-2 and target protein kinase C pathways to induce apoptosis. Mol. Cancer Ther. 1 (2002) 469-481
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 469-481
-
-
Barrett, C.M.1
Lewis, F.L.2
Roaten, J.B.3
Sweatman, T.W.4
Israel, M.5
Cleveland, J.L.6
Lothstein, L.7
-
5
-
-
0035797151
-
Mitochondria as subcellular targets for clinically useful anthracyclines
-
Jung K., and Reszka R. Mitochondria as subcellular targets for clinically useful anthracyclines. Adv. Drug Deliv. Rev. 49 (2001) 87-105
-
(2001)
Adv. Drug Deliv. Rev.
, vol.49
, pp. 87-105
-
-
Jung, K.1
Reszka, R.2
-
6
-
-
19544371393
-
Coenzyme q10 for prevention of anthracycline-induced cardiotoxicity
-
Conklin K.A. Coenzyme q10 for prevention of anthracycline-induced cardiotoxicity. Integr. Cancer Ther. 4 (2005) 110-130
-
(2005)
Integr. Cancer Ther.
, vol.4
, pp. 110-130
-
-
Conklin, K.A.1
-
7
-
-
0043237846
-
Doxorubicin-induced cardiac mitochondrionopathy
-
Wallace K.B. Doxorubicin-induced cardiac mitochondrionopathy. Pharmacol. Toxicol. 93 (2003) 105-115
-
(2003)
Pharmacol. Toxicol.
, vol.93
, pp. 105-115
-
-
Wallace, K.B.1
-
9
-
-
0016697458
-
Adriamycin-induced cardiac damage in the mouse: a small-animal model of cardiotoxicity
-
Rosenoff S.H., Olson H.M., Young D.M., Bostick F., and Young R.C. Adriamycin-induced cardiac damage in the mouse: a small-animal model of cardiotoxicity. J. Natl. Cancer Inst. 55 (1975) 191-194
-
(1975)
J. Natl. Cancer Inst.
, vol.55
, pp. 191-194
-
-
Rosenoff, S.H.1
Olson, H.M.2
Young, D.M.3
Bostick, F.4
Young, R.C.5
-
10
-
-
0025193951
-
Structure of the adriamycin-cardiolipin complex. Role in mitochondrial toxicity
-
Goormaghtigh E., Huart P., Praet M., Brasseur R., and Ruysschaert J.M. Structure of the adriamycin-cardiolipin complex. Role in mitochondrial toxicity. Biophys. Chem. 35 (1990) 247-257
-
(1990)
Biophys. Chem.
, vol.35
, pp. 247-257
-
-
Goormaghtigh, E.1
Huart, P.2
Praet, M.3
Brasseur, R.4
Ruysschaert, J.M.5
-
11
-
-
0022399953
-
Adriamycin as a probe for the transversal distribution of cardiolipin in the inner mitochondrial membrane
-
Cheneval D., Muller M., Toni R., Ruetz S., and Carafoli E. Adriamycin as a probe for the transversal distribution of cardiolipin in the inner mitochondrial membrane. J. Biol. Chem. 260 (1985) 13003-13007
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 13003-13007
-
-
Cheneval, D.1
Muller, M.2
Toni, R.3
Ruetz, S.4
Carafoli, E.5
-
12
-
-
0021742903
-
The interaction of adriamycin with cardiolipin in model and rat liver mitochondrial membranes
-
Nicolay K., Timmers R.J., Spoelstra E., Van der Neut R., Fok J.J., Huigen Y.M., Verkleij A.J., and De Kruijff B. The interaction of adriamycin with cardiolipin in model and rat liver mitochondrial membranes. Biochim. Biophys. Acta 778 (1984) 359-371
-
(1984)
Biochim. Biophys. Acta
, vol.778
, pp. 359-371
-
-
Nicolay, K.1
Timmers, R.J.2
Spoelstra, E.3
Van der Neut, R.4
Fok, J.J.5
Huigen, Y.M.6
Verkleij, A.J.7
De Kruijff, B.8
-
13
-
-
0034651715
-
Interstrand cross-linking by adriamycin in nuclear and mitochondrial DNA of MCF-7 cells
-
Cullinane C., Cutts S.M., Panousis C., and Phillips D.R. Interstrand cross-linking by adriamycin in nuclear and mitochondrial DNA of MCF-7 cells. Nucleic Acids Res. 28 (2000) 1019-1025
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 1019-1025
-
-
Cullinane, C.1
Cutts, S.M.2
Panousis, C.3
Phillips, D.R.4
-
14
-
-
0030880285
-
Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin
-
Palmeira C.M., Serrano J., Kuehl D.W., and Wallace K.B. Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin. Biochim. Biophys. Acta 1321 (1997) 101-106
-
(1997)
Biochim. Biophys. Acta
, vol.1321
, pp. 101-106
-
-
Palmeira, C.M.1
Serrano, J.2
Kuehl, D.W.3
Wallace, K.B.4
-
15
-
-
0242442100
-
Time-dependent and tissue-specific accumulation of mtDNA and respiratory chain defects in chronic doxorubicin cardiomyopathy
-
Lebrecht D., Setzer B., Ketelsen U.P., Haberstroh J., and Walker U.A. Time-dependent and tissue-specific accumulation of mtDNA and respiratory chain defects in chronic doxorubicin cardiomyopathy. Circulation 108 (2003) 2423-2429
-
(2003)
Circulation
, vol.108
, pp. 2423-2429
-
-
Lebrecht, D.1
Setzer, B.2
Ketelsen, U.P.3
Haberstroh, J.4
Walker, U.A.5
-
16
-
-
29744457780
-
Tissue-specific mtDNA lesions and radical-associated mitochondrial dysfunction in human hearts exposed to doxorubicin
-
Lebrecht D., Kokkori A., Ketelsen U.P., Setzer B., and Walker U.A. Tissue-specific mtDNA lesions and radical-associated mitochondrial dysfunction in human hearts exposed to doxorubicin. J. Pathol. 207 (2005) 436-444
-
(2005)
J. Pathol.
, vol.207
, pp. 436-444
-
-
Lebrecht, D.1
Kokkori, A.2
Ketelsen, U.P.3
Setzer, B.4
Walker, U.A.5
-
17
-
-
33744959330
-
Defective one- or two-electron reduction of the anticancer anthracycline epirubicin in human heart. Relative importance of vesicular sequestration and impaired efficiency of electron addition
-
Salvatorelli E., Guarnieri S., Menna P., Liberi G., Calafiore A.M., Mariggio M.A., Mordente A., Gianni L., and Minotti G. Defective one- or two-electron reduction of the anticancer anthracycline epirubicin in human heart. Relative importance of vesicular sequestration and impaired efficiency of electron addition. J. Biol. Chem. 281 (2006) 10990-11001
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 10990-11001
-
-
Salvatorelli, E.1
Guarnieri, S.2
Menna, P.3
Liberi, G.4
Calafiore, A.M.5
Mariggio, M.A.6
Mordente, A.7
Gianni, L.8
Minotti, G.9
-
18
-
-
0022585397
-
Cytofluorescence detection of adriamycin-mitochondria interactions in isolated. Perfused rat heart
-
Nicolay K., Fok J.J., Voorhout W., Post J.A., and de Kruijff B. Cytofluorescence detection of adriamycin-mitochondria interactions in isolated. Perfused rat heart. Biochim. Biophys. Acta 887 (1986) 35-41
-
(1986)
Biochim. Biophys. Acta
, vol.887
, pp. 35-41
-
-
Nicolay, K.1
Fok, J.J.2
Voorhout, W.3
Post, J.A.4
de Kruijff, B.5
-
19
-
-
0035053943
-
Differences in the intracellular distribution of acid-sensitive doxorubicin-protein conjugates in comparison to free and liposomal formulated doxorubicin as shown by confocal microscopy
-
Beyer U., Rothern-Rutishauser B., Unger C., Wunderli-Allenspach H., and Kratz F. Differences in the intracellular distribution of acid-sensitive doxorubicin-protein conjugates in comparison to free and liposomal formulated doxorubicin as shown by confocal microscopy. Pharm. Res. 18 (2001) 29-38
-
(2001)
Pharm. Res.
, vol.18
, pp. 29-38
-
-
Beyer, U.1
Rothern-Rutishauser, B.2
Unger, C.3
Wunderli-Allenspach, H.4
Kratz, F.5
-
20
-
-
0018077370
-
Effect of adriamycin and analogs on the nuclear fluorescence of propidium iodide-stained cells
-
Krishan A., Ganapathi R.N., and Israel M. Effect of adriamycin and analogs on the nuclear fluorescence of propidium iodide-stained cells. Cancer Res. 38 (1978) 3656-3662
-
(1978)
Cancer Res.
, vol.38
, pp. 3656-3662
-
-
Krishan, A.1
Ganapathi, R.N.2
Israel, M.3
-
21
-
-
0026482792
-
Intercalation of anthracyclines into living cell DNA analyzed by flow cytometry
-
Belloc F., Lacombe F., Dumain P., Lopez F., Bernard P., Boisseau M.R., and Reifers J. Intercalation of anthracyclines into living cell DNA analyzed by flow cytometry. Cytometry 13 (1992) 880-885
-
(1992)
Cytometry
, vol.13
, pp. 880-885
-
-
Belloc, F.1
Lacombe, F.2
Dumain, P.3
Lopez, F.4
Bernard, P.5
Boisseau, M.R.6
Reifers, J.7
-
22
-
-
34447315023
-
Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances
-
Ashley N., Adams S., Slama A., Zeviani M., Suomalainen A., Andreu A.L., Naviaux R.K., and Poulton J. Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances. Hum. Mol. Genet. 16 (2007) 1400-1411
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 1400-1411
-
-
Ashley, N.1
Adams, S.2
Slama, A.3
Zeviani, M.4
Suomalainen, A.5
Andreu, A.L.6
Naviaux, R.K.7
Poulton, J.8
-
23
-
-
12344293822
-
Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining
-
Ashley N., Harris D., and Poulton J. Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining. Exp. Cell Res. 303 (2005) 432-446
-
(2005)
Exp. Cell Res.
, vol.303
, pp. 432-446
-
-
Ashley, N.1
Harris, D.2
Poulton, J.3
-
24
-
-
48249120297
-
Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations
-
Ashley N., O'Rourke A., Smith C., Adams S., Gowda V., Zeviani M., Brown G.K., Fratter C., and Poulton J. Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations. Hum. Mol. Genet. 17 (2008) 2496-2506
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 2496-2506
-
-
Ashley, N.1
O'Rourke, A.2
Smith, C.3
Adams, S.4
Gowda, V.5
Zeviani, M.6
Brown, G.K.7
Fratter, C.8
Poulton, J.9
-
25
-
-
36048966317
-
Liver mtDNA content increases during development: a comparison of methods and the importance of age- and tissue-specific controls for the diagnosis of mtDNA depletion
-
Morten K.J., Ashley N., Wijburg F., Hadzic N., Parr J., Jayawant S., Adams S., Bindoff L., Bakker H.D., Mieli-Vergani G., Zeviani M., and Poulton J. Liver mtDNA content increases during development: a comparison of methods and the importance of age- and tissue-specific controls for the diagnosis of mtDNA depletion. Mitochondrion 7 (2007) 386-395
-
(2007)
Mitochondrion
, vol.7
, pp. 386-395
-
-
Morten, K.J.1
Ashley, N.2
Wijburg, F.3
Hadzic, N.4
Parr, J.5
Jayawant, S.6
Adams, S.7
Bindoff, L.8
Bakker, H.D.9
Mieli-Vergani, G.10
Zeviani, M.11
Poulton, J.12
-
26
-
-
0036843327
-
Cardiolipin deficiency in X-linked cardioskeletal myopathy and neutropenia (Barth syndrome, MIM 302060): a study in cultured skin fibroblasts
-
Valianpour F., Wanders R.J., Overmars H., Vreken P., Van Gennip A.H., Baas F., Plecko B., Santer R., Becker K., and Barth P.G. Cardiolipin deficiency in X-linked cardioskeletal myopathy and neutropenia (Barth syndrome, MIM 302060): a study in cultured skin fibroblasts. J. Pediatr. 141 (2002) 729-733
-
(2002)
J. Pediatr.
, vol.141
, pp. 729-733
-
-
Valianpour, F.1
Wanders, R.J.2
Overmars, H.3
Vreken, P.4
Van Gennip, A.H.5
Baas, F.6
Plecko, B.7
Santer, R.8
Becker, K.9
Barth, P.G.10
-
27
-
-
0029942597
-
Comparative evaluation of the intracellular accumulation and DNA binding of idarubicin and daunorubicin in sensitive and multidrug-resistant human leukaemia K562 cells
-
Bogush T., and Robert J. Comparative evaluation of the intracellular accumulation and DNA binding of idarubicin and daunorubicin in sensitive and multidrug-resistant human leukaemia K562 cells. Anticancer Res. 16 (1996) 365-368
-
(1996)
Anticancer Res.
, vol.16
, pp. 365-368
-
-
Bogush, T.1
Robert, J.2
-
28
-
-
50249148905
-
Cardiolipin, the heart of mitochondrial metabolism
-
Houtkooper R.H., and Vaz F.M. Cardiolipin, the heart of mitochondrial metabolism. Cell. Mol. Life Sci. 65 (2008) 2493-2506
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 2493-2506
-
-
Houtkooper, R.H.1
Vaz, F.M.2
-
29
-
-
0024448458
-
Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation
-
King M.P., and Attardi G. Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation. Science 246 (1989) 500-503
-
(1989)
Science
, vol.246
, pp. 500-503
-
-
King, M.P.1
Attardi, G.2
-
30
-
-
19944383101
-
Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number
-
Tyynismaa H., Sembongi H., Bokori-Brown M., Granycome C., Ashley N., Poulton J., Jalanko A., Spelbrink J.N., Holt I.J., and Suomalainen A. Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number. Hum. Mol. Genet. 13 (2004) 3219-3227
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 3219-3227
-
-
Tyynismaa, H.1
Sembongi, H.2
Bokori-Brown, M.3
Granycome, C.4
Ashley, N.5
Poulton, J.6
Jalanko, A.7
Spelbrink, J.N.8
Holt, I.J.9
Suomalainen, A.10
|