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Volumn 22, Issue 1, 2009, Pages 61-68

Quality of life and neurotic disorders in general healthcare

Author keywords

Anxiety; Depression; Quality of life; Somatization

Indexed keywords

ANXIETY DISORDER; COMORBIDITY; DEPRESSION; HEALTH CARE; HUMAN; NEUROSIS; POPULATION RESEARCH; PREVALENCE; PRIMARY MEDICAL CARE; PSYCHOTHERAPY; PUBLIC HEALTH; QUALITY OF LIFE; QUESTIONNAIRE; REVIEW; SOMATIZATION; SOMATOFORM DISORDER; WORLD HEALTH ORGANIZATION;

EID: 57749175793     PISSN: 09517367     EISSN: None     Source Type: Journal    
DOI: 10.1097/YCO.0b013e32831a4750     Document Type: Review
Times cited : (16)

References (43)
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    • Reynolds SL, Haley WE, Kozlenko N. The impact of depressive symptoms and chronic diseases on active life expectancy in older Americans. Am J Geriatr Psychiatry 2008; 16:425-432. An analysis of data from a nationally (USA) representative sample of community-dwelling adults age 70 years and older (n = 7381) enrolled in a prospective cohort study, the asset and health dynamics among the oldest old, examined whether depressive symptoms negatively affected ALE, or remaining years free of disability, and mortality. ALE was defined as life with no subjective difficulty performing any functions necessary for the activities of daily living.
    • Reynolds SL, Haley WE, Kozlenko N. The impact of depressive symptoms and chronic diseases on active life expectancy in older Americans. Am J Geriatr Psychiatry 2008; 16:425-432. An analysis of data from a nationally (USA) representative sample of community-dwelling adults age 70 years and older (n = 7381) enrolled in a prospective cohort study, the asset and health dynamics among the oldest old, examined whether depressive symptoms negatively affected ALE, or remaining years free of disability, and mortality. ALE was defined as life with no subjective difficulty performing any functions necessary for the activities of daily living.
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    • Fava GS, Sonini N. The biopsychosocial model thirty years later. Psychother Psychosom 2008; 77:1-2. In a reflection on the biopsychosocial model of disease 30 years after its acclaimed description by George Engel, the authors comment that the need to include consideration of function in daily life, productivity, performance of social roles, intellectual capacity, emotional stability and well being, has emerged as central to clinical investigation and patient care. This is particularly important in chronic diseases in which cure cannot take place. It is critical to the patients and their families and to the care providers.
    • Fava GS, Sonini N. The biopsychosocial model thirty years later. Psychother Psychosom 2008; 77:1-2. In a reflection on the biopsychosocial model of disease 30 years after its acclaimed description by George Engel, the authors comment that the need to include consideration of function in daily life, productivity, performance of social roles, intellectual capacity, emotional stability and well being, has emerged as central to clinical investigation and patient care. This is particularly important in chronic diseases in which cure cannot take place. It is critical to the patients and their families and to the care providers.
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    • Measuring health-related quality of life in patients with irritable bowel syndrome: Can less be more?
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    • Moussavi S, Chatterji S, Verdes E, et al. Depression, chronic diseases, and decrements in health: results from the World Health Survey. Lancet 2007; 370:851-858. An analysis of data from the WHO WHS indicates that the comorbid state of depression incrementally worsens health (including assessment of QoL) compared with depression alone, with any of the chronic diseases alone, and with any combination of chronic diseases without depression. Consistently across countries and different demographic characteristics, respondents with depression comorbid with one or more chronic diseases have the worst health scores of all the disease states.
    • Moussavi S, Chatterji S, Verdes E, et al. Depression, chronic diseases, and decrements in health: results from the World Health Survey. Lancet 2007; 370:851-858. An analysis of data from the WHO WHS indicates that the comorbid state of depression incrementally worsens health (including assessment of QoL) compared with depression alone, with any of the chronic diseases alone, and with any combination of chronic diseases without depression. Consistently across countries and different demographic characteristics, respondents with depression comorbid with one or more chronic diseases have the worst health scores of all the disease states.
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    • Diabetes, common mental disorders, and disability: Findings from the UK National Psychiatric Morbidity Survey
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    • Das-Munshi J, Goldberg D, Bebbington PE, et al. Public health significance of mixed anxiety and depression: beyond current classification. Br J Psychiatry 2008; 192:171-177. By using data from the Great Britain National Psychiatric Morbidity survey of 2000, decrements in a variety of indicators of QoL were compared between people with pure ICD-10 depressive disorder, pure ICD-10 anxiety disorder, comorbid depressive and anxiety disorders, and MADD. QoL was assessed using six indicators covering health, mental well being and physical, social and occupational functioning: self-reported global health; self-reported (lifetime) suicide attempt; physical functioning and social and occupational functioning derived from SF12; whether currently employed, unemployed or economically inactive and days off work in the previous year
    • Das-Munshi J, Goldberg D, Bebbington PE, et al. Public health significance of mixed anxiety and depression: beyond current classification. Br J Psychiatry 2008; 192:171-177. By using data from the Great Britain National Psychiatric Morbidity survey of 2000, decrements in a variety of indicators of QoL were compared between people with pure ICD-10 depressive disorder, pure ICD-10 anxiety disorder, comorbid depressive and anxiety disorders, and MADD. QoL was assessed using six indicators covering health, mental well being and physical, social and occupational functioning: self-reported global health; self-reported (lifetime) suicide attempt; physical functioning and social and occupational functioning derived from SF12; whether currently employed, unemployed or economically inactive and days off work in the previous year.
  • 14
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    • Strine TW, Chapman DP, Balluz LS, et al. The associations between life satisfaction and health-related quality of life, chronic illness, and health behaviors among U.S. community-dwelling adults. J Community Health 2008; 33:40-50. Data from the 2005 Behavioral Risk Factor Surveillance System (BRFSS, a telephone survey of adults in the United States population living outside institutions, were analysed to examine the associations between life satisfaction level and QoL, chronic illness, and adverse health behaviours. Life satisfaction was evaluated by asking 'In general, how satisfied are you with your life, and QoL by four questions about the recent quality of general health, physical hearth, mental health and consequent activity limitations CDC HRQOL, This study reports a significant burden of chronic illness, disability and poor QoL in the United States general population
    • Strine TW, Chapman DP, Balluz LS, et al. The associations between life satisfaction and health-related quality of life, chronic illness, and health behaviors among U.S. community-dwelling adults. J Community Health 2008; 33:40-50. Data from the 2005 Behavioral Risk Factor Surveillance System (BRFSS), a telephone survey of adults in the United States population living outside institutions, were analysed to examine the associations between life satisfaction level and QoL, chronic illness, and adverse health behaviours. Life satisfaction was evaluated by asking 'In general, how satisfied are you with your life?' and QoL by four questions about the recent quality of general health, physical hearth, mental health and consequent activity limitations (CDC HRQOL). This study reports a significant burden of chronic illness, disability and poor QoL in the United States general population.
  • 15
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    • Contribution to the construct validity of the Perceived Stress Questionnaire from a population-based survey
    • SF8 was used to assess QoL in a large population study in Germany designed to test the Perceived Stress Questionnaire PSQ
    • Kocalevent RD, Levenstein S, Fliege H, et al. Contribution to the construct validity of the Perceived Stress Questionnaire from a population-based survey. J Psychosom Res 2007; 63:71-81. SF8 was used to assess QoL in a large population study in Germany designed to test the Perceived Stress Questionnaire (PSQ).
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    • Bleichhardt G, Hiller W. Hypochondriasis and health anxiety in the German population. Br J Health Psychol 2007; 12 (Pt 4):511-523. In a survey of a convenience sample of 1575 community individuals, the authors measured QoL with one item adapted from the EuroQoL: 'How good or bad is your state of health today?' and use of a visual analogue scale. This measure allowed discrimination between those with and without health anxiety.
    • Bleichhardt G, Hiller W. Hypochondriasis and health anxiety in the German population. Br J Health Psychol 2007; 12 (Pt 4):511-523. In a survey of a convenience sample of 1575 community individuals, the authors measured QoL with one item adapted from the EuroQoL: 'How good or bad is your state of health today?' and use of a visual analogue scale. This measure allowed discrimination between those with and without health anxiety.
  • 17
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    • Levenson JL, McClish DK, Dahman BA, et al. Depression and anxiety in adults with sickle cell disease: the PiSCES project. Psychosom Med 2008; 70:192-196. The Pain in Sickle Cell Epidemiology Study (PiSCES) is a prospective cohort study in 308 adults with sickle cell disease in Virginia, USA. Baseline variables included demographics, genotype, laboratory data, QoL, depression, and anxiety. Patients completed daily diaries for up to 6 months, reporting sickle cell pain intensity, distress, interference, whether they were in a sickle cell crisis, as well as healthcare and opioid utilization.
    • Levenson JL, McClish DK, Dahman BA, et al. Depression and anxiety in adults with sickle cell disease: the PiSCES project. Psychosom Med 2008; 70:192-196. The Pain in Sickle Cell Epidemiology Study (PiSCES) is a prospective cohort study in 308 adults with sickle cell disease in Virginia, USA. Baseline variables included demographics, genotype, laboratory data, QoL, depression, and anxiety. Patients completed daily diaries for up to 6 months, reporting sickle cell pain intensity, distress, interference, whether they were in a sickle cell crisis, as well as healthcare and opioid utilization.
  • 18
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    • Pier C, Shandley KA, Fisher JL, et al. Identifying the health and mental health information needs of people with coronary heart disease, with and without depression. Med J Aust 2008; 188:S142-S144. A qualitative study conducted in Melbourne, with thematic analysis of semi-structured interviews on the types of health information that patients with coronary heart disease (CHD) considered useful to assist with the management of their illness.
    • Pier C, Shandley KA, Fisher JL, et al. Identifying the health and mental health information needs of people with coronary heart disease, with and without depression. Med J Aust 2008; 188:S142-S144. A qualitative study conducted in Melbourne, with thematic analysis of semi-structured interviews on the types of health information that patients with coronary heart disease (CHD) considered useful to assist with the management of their illness.
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    • Artham SM, Lavie CJ, Milani RV. Cardiac rehabilitation programs markedly improve high-risk profiles in coronary patients with high psychological distress. South Med J 2008; 101:262-267. The impact of cardiac rehabilitation and exercise training (CRET) programmes was investigated in 224 patients with CAD. QoL was assessed by using SF36 as an indicator of health status and outcome of the intervention. Those with high psychological distress and high-risk behavioural characteristics had the most marked improvement in health status. This study supports the specific targeting of cardiac rehabilitation interventions to those with comorbid psychological distress.
    • Artham SM, Lavie CJ, Milani RV. Cardiac rehabilitation programs markedly improve high-risk profiles in coronary patients with high psychological distress. South Med J 2008; 101:262-267. The impact of cardiac rehabilitation and exercise training (CRET) programmes was investigated in 224 patients with CAD. QoL was assessed by using SF36 as an indicator of health status and outcome of the intervention. Those with high psychological distress and high-risk behavioural characteristics had the most marked improvement in health status. This study supports the specific targeting of cardiac rehabilitation interventions to those with comorbid psychological distress.
  • 20
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    • Lavie CJ, Milani RV. Adverse psychological and coronary risk profiles in young patients with coronary artery disease and benefits of formal cardiac rehabilitation. Arch Intern Med 2006; 166:1878-1883. Baseline behavioral data, QoL (using SF36), and risk profiles in 635 consecutive hospital patients with CAD were measured before and after CRET, and specifically assessed data in 104 young patients compared with 260 elderly patients. The findings include the adverse psychological and CAD risk profiles that are present in young patients, and are consistent with substantial benefit of formal CRET programmes in younger adults.
    • Lavie CJ, Milani RV. Adverse psychological and coronary risk profiles in young patients with coronary artery disease and benefits of formal cardiac rehabilitation. Arch Intern Med 2006; 166:1878-1883. Baseline behavioral data, QoL (using SF36), and risk profiles in 635 consecutive hospital patients with CAD were measured before and after CRET, and specifically assessed data in 104 young patients compared with 260 elderly patients. The findings include the adverse psychological and CAD risk profiles that are present in young patients, and are consistent with substantial benefit of formal CRET programmes in younger adults.
  • 21
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    • Lewin RJ, Coulton S, Frizelle DJ, et al. A brief cognitive behavioural pre-implantation and rehabilitation programme for patients receiving an implantable cardioverter defibrillator improves physical health and reduces psychological morbidity and unplanned re-admissions. Heart 2007 [Epub 2007 Dec 10]. A prospective multicentred, intention-to-treat cluster randomized controlled trial was conducted at eight centres in the UK with a consecutive series of patients undergoing implantation with an ICD.
    • Lewin RJ, Coulton S, Frizelle DJ, et al. A brief cognitive behavioural pre-implantation and rehabilitation programme for patients receiving an implantable cardioverter defibrillator improves physical health and reduces psychological morbidity and unplanned re-admissions. Heart 2007 [Epub 2007 Dec 10]. A prospective multicentred, intention-to-treat cluster randomized controlled trial was conducted at eight centres in the UK with a consecutive series of patients undergoing implantation with an ICD.
  • 22
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    • Yohannes AM, Baldwin RC, Connolly MJ. Prevalence of depression and anxiety symptoms in elderly patients admitted in post-acute intermediate care. Int J Geriatr Psychiatry 2008 [Epub 2008 May 6]. In a UK study of 173 elderly patients admitted to a postacute rehabilitation ward with various medical conditions, depressive and anxiety symptoms were common, and 17% met diagnostic criteria for a major depressive disorder. Depression, anxiety and poor QoL as assessed by SF36 tended to occur together and prolonged inpatient stay in the rehabilitation ward was associated with the severity of depression, cognitive impairment, physical disability and social isolation.
    • Yohannes AM, Baldwin RC, Connolly MJ. Prevalence of depression and anxiety symptoms in elderly patients admitted in post-acute intermediate care. Int J Geriatr Psychiatry 2008 [Epub 2008 May 6]. In a UK study of 173 elderly patients admitted to a postacute rehabilitation ward with various medical conditions, depressive and anxiety symptoms were common, and 17% met diagnostic criteria for a major depressive disorder. Depression, anxiety and poor QoL as assessed by SF36 tended to occur together and prolonged inpatient stay in the rehabilitation ward was associated with the severity of depression, cognitive impairment, physical disability and social isolation.
  • 23
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    • Janson Fagring A, Kjellgren KI, Rosengren A, et al. Depression, anxiety, stress, social interaction and health-related quality of life in men and women with unexplained chest pain. BMC Public Health 2008; 8:165. Consecutive hospital patients with UCP in Sweden were compared with a population reference group, using a questionnaire that included rating scales for anxiety and depression symptoms and social interaction, and SF36. The patients were more likely than referents to be immigrants and the men to have stress at work.
    • Janson Fagring A, Kjellgren KI, Rosengren A, et al. Depression, anxiety, stress, social interaction and health-related quality of life in men and women with unexplained chest pain. BMC Public Health 2008; 8:165. Consecutive hospital patients with UCP in Sweden were compared with a population reference group, using a questionnaire that included rating scales for anxiety and depression symptoms and social interaction, and SF36. The patients were more likely than referents to be immigrants and the men to have stress at work.
  • 24
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    • Kulcu DG, Kurtais Y, Tur BS, et al. The effect of cardiac rehabilitation on quality of life, anxiety and depression in patients with congestive heart failure. A randomized controlled trial, short-term results. Eura Medicophys 2007; 43:489-497. Participation in an exercise programme by elderly patients with congestive heart failure was associated over 8 weeks with an improvement in anxiety and depressive symptoms and physical health but not in a specific measure of QoL. QoL was assessed with a questionnaire specific to heart disease that incorporated items regarding sexual life, work status and social life. The authors comment that this may not be the appropriate tool for the patient population who were mainly elderly, retired and housewives, and the assessment of QoL may not show differences in the short term
    • Kulcu DG, Kurtais Y, Tur BS, et al. The effect of cardiac rehabilitation on quality of life, anxiety and depression in patients with congestive heart failure. A randomized controlled trial, short-term results. Eura Medicophys 2007; 43:489-497. Participation in an exercise programme by elderly patients with congestive heart failure was associated over 8 weeks with an improvement in anxiety and depressive symptoms and physical health but not in a specific measure of QoL. QoL was assessed with a questionnaire specific to heart disease that incorporated items regarding sexual life, work status and social life. The authors comment that this may not be the appropriate tool for the patient population who were mainly elderly, retired and housewives, and the assessment of QoL may not show differences in the short term.
  • 25
    • 34147144012 scopus 로고    scopus 로고
    • Tracy JI, Dechant V, Sperling MR, et al. The association of mood with quality of life ratings in epilepsy. Neurology 2007; 68:1101-1107. The study was designed to determine the relative contributions of psychological (mood and anxiety), social, and seizure-related variables to QoL scores in epilepsy and assessed 435 outpatients with epilepsy. The participants completed the QoL in Epilepsy 31 Inventory (QOLIE-31), Beck Depression Inventory II (BDI-II), Beck Anxiety Inventory, and a social survey.
    • Tracy JI, Dechant V, Sperling MR, et al. The association of mood with quality of life ratings in epilepsy. Neurology 2007; 68:1101-1107. The study was designed to determine the relative contributions of psychological (mood and anxiety), social, and seizure-related variables to QoL scores in epilepsy and assessed 435 outpatients with epilepsy. The participants completed the QoL in Epilepsy 31 Inventory (QOLIE-31), Beck Depression Inventory II (BDI-II), Beck Anxiety Inventory, and a social survey.
  • 26
    • 33846042504 scopus 로고    scopus 로고
    • Ng T-P, Niti M, Tan W-C, et al. Depressive symptoms and chronic obstructive pulmonary disease: effect on mortality, hospital readmission, symptom burden, functional status, and quality of life. Arch Intern Med 2007; 167:60-67. In a prospective cohort study from Singapore, 376 consecutive patients with COPD hospitalized for acute exacerbation were followed for 1 year. QoL was assessed with the SGRQ, a self-administered, disease-specific, health-related QoL questionnaire with 50 items. The questionnaire assesses the patient's experience of symptoms, the amount of distress caused by symptoms, and the extent to which symptoms such as breathlessness have limited activities of daily living in the past 12 months. The SGRQ has been previously validated for use in Chinese patients.
    • Ng T-P, Niti M, Tan W-C, et al. Depressive symptoms and chronic obstructive pulmonary disease: effect on mortality, hospital readmission, symptom burden, functional status, and quality of life. Arch Intern Med 2007; 167:60-67. In a prospective cohort study from Singapore, 376 consecutive patients with COPD hospitalized for acute exacerbation were followed for 1 year. QoL was assessed with the SGRQ, a self-administered, disease-specific, health-related QoL questionnaire with 50 items. The questionnaire assesses the patient's experience of symptoms, the amount of distress caused by symptoms, and the extent to which symptoms such as breathlessness have limited activities of daily living in the past 12 months. The SGRQ has been previously validated for use in Chinese patients.
  • 27
    • 34250755342 scopus 로고    scopus 로고
    • Rosendal M, Olesen F, Fink P, et al. A randomized controlled trial of brief training in the assessment and treatment of somatization in primary care: effects on patient outcome. Gen Hosp Psychiatry 2007; 29:364-373. The study was set in a mixed rural-metropolitan area in Denmark with 350 000 inhabitants served by 121 family physician practices. It investigated how to improve care for somatizing patients in primary care and whether educational interventions for physicians also affect patient outcome. SF36 was used as the measure of QoL and an outcome indicator.
    • Rosendal M, Olesen F, Fink P, et al. A randomized controlled trial of brief training in the assessment and treatment of somatization in primary care: effects on patient outcome. Gen Hosp Psychiatry 2007; 29:364-373. The study was set in a mixed rural-metropolitan area in Denmark with 350 000 inhabitants served by 121 family physician practices. It investigated how to improve care for somatizing patients in primary care and whether educational interventions for physicians also affect patient outcome. SF36 was used as the measure of QoL and an outcome indicator.
  • 28
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    • Pols RG, Battersby MW. Coordinated care in the management of patients with unexplained physical symptoms: depression is a key issue. Med J Aust 2008; 188:S133-S137. Patients presenting with somatization were included in an Australian trial of coordinated care. In a randomized controlled trial (RCT) of 124 patients, the care plan included treatment for depression and anxiety disorders, a containment strategy for somatization, and service coordinator-assisted self-management. Control patients received standard treatment. QoL was assessed with SF36. General physicians require training in the diagnosis of depression and how to say 'no' to patients with unexplained physical symptoms who request further unnecessary investigations or referrals.
    • Pols RG, Battersby MW. Coordinated care in the management of patients with unexplained physical symptoms: depression is a key issue. Med J Aust 2008; 188:S133-S137. Patients presenting with somatization were included in an Australian trial of coordinated care. In a randomized controlled trial (RCT) of 124 patients, the care plan included treatment for depression and anxiety disorders, a containment strategy for somatization, and service coordinator-assisted self-management. Control patients received standard treatment. QoL was assessed with SF36. General physicians require training in the diagnosis of depression and how to say 'no' to patients with unexplained physical symptoms who request further unnecessary investigations or referrals.
  • 29
    • 34948904837 scopus 로고    scopus 로고
    • Schweickhardt A, Larisch A, Wirsching M, Fritzsche K. Short-term psychotherapeutic interventions for somatizing patients in the general hospital: a randomized controlled study. Psychother Psychosom 2007; 76:339-346. A randomized controlled study of 91 patients in Germany investigated the potential benefits of a modified short-term psychotherapy programme for general hospital patients. Patients from the intervention group were significantly more motivated for psychotherapy.
    • Schweickhardt A, Larisch A, Wirsching M, Fritzsche K. Short-term psychotherapeutic interventions for somatizing patients in the general hospital: a randomized controlled study. Psychother Psychosom 2007; 76:339-346. A randomized controlled study of 91 patients in Germany investigated the potential benefits of a modified short-term psychotherapy programme for general hospital patients. Patients from the intervention group were significantly more motivated for psychotherapy.
  • 31
    • 48449102229 scopus 로고    scopus 로고
    • Kritz-Silverstein D, von Muhlen D, Laughlin GA, Bettencourt R. Effects of dehydroepiandrosterone supplementation on cognitive function and quality of life: the DHEA and Well Ness (DAWN) trial. J Am Geriatr Soc 2008; 56:1292-1298. A double-blind, randomized controlled clinical trial of DHEA supplements in a clinical research facility in California found no benefit in healthy older adults on cognitive performance or QoL as assessed using SF36. The authors comment that it should not be recommended for that purpose in the general population.
    • Kritz-Silverstein D, von Muhlen D, Laughlin GA, Bettencourt R. Effects of dehydroepiandrosterone supplementation on cognitive function and quality of life: the DHEA and Well Ness (DAWN) trial. J Am Geriatr Soc 2008; 56:1292-1298. A double-blind, randomized controlled clinical trial of DHEA supplements in a clinical research facility in California found no benefit in healthy older adults on cognitive performance or QoL as assessed using SF36. The authors comment that it should not be recommended for that purpose in the general population.
  • 32
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    • Barbuto JP, White GL Jr, Porucznik CA, Holmes EB. Chronic pain: second, do no harm. Am J Phys Med Rehabil 2007; 87:78-83. This useful essay notes that pain may be undertreated, contributing to anguish, overtreated, inadvertently contributing to drug addiction, drug diversion, and even death, and misunderstood, contributing to chronicity. Optimal treatment of chronic pain may be assisted by an adequate model of appraisal, treatment focused on pathophysiology (whether physical, psychosocial, or some combination of these), and frequent reassessment of total social function - or QoL.
    • Barbuto JP, White GL Jr, Porucznik CA, Holmes EB. Chronic pain: second, do no harm. Am J Phys Med Rehabil 2007; 87:78-83. This useful essay notes that pain may be undertreated, contributing to anguish, overtreated, inadvertently contributing to drug addiction, drug diversion, and even death, and misunderstood, contributing to chronicity. Optimal treatment of chronic pain may be assisted by an adequate model of appraisal, treatment focused on pathophysiology (whether physical, psychosocial, or some combination of these), and frequent reassessment of total social function - or QoL.
  • 33
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    • Tschan R, Wiltink J, Best C, et al. Validation of the German version of the Vertigo Symptom Scale (VSS) in patients with organic or somatoform dizziness and healthy controls. J Neurol 2008 [Epub 2008 May 16]. In a study designed to validate the German version of the Vertigo Symptom Scale (VSS), SF36 scores discriminated between dizziness patients and healthy controls, and scores for the mental health component were lower among those with psychogenic dizziness than among those with organic dizziness.
    • Tschan R, Wiltink J, Best C, et al. Validation of the German version of the Vertigo Symptom Scale (VSS) in patients with organic or somatoform dizziness and healthy controls. J Neurol 2008 [Epub 2008 May 16]. In a study designed to validate the German version of the Vertigo Symptom Scale (VSS), SF36 scores discriminated between dizziness patients and healthy controls, and scores for the mental health component were lower among those with psychogenic dizziness than among those with organic dizziness.
  • 34
    • 40249092059 scopus 로고    scopus 로고
    • Psychiatric diagnoses of patients with psychogenic nonepileptic seizures
    • Marchetti RL, Kurcgant D, Neto JG, et al. Psychiatric diagnoses of patients with psychogenic nonepileptic seizures. Seizure 2008; 17:247-253.
    • (2008) Seizure , vol.17 , pp. 247-253
    • Marchetti, R.L.1    Kurcgant, D.2    Neto, J.G.3
  • 35
    • 38049036405 scopus 로고    scopus 로고
    • Impact of psychogenic movement disorders versus Parkinson's on disability, quality of life, and psychopathology
    • A study of 66 specialist hospital inpatients with PMDs or Parkinson's disease used SF12 to assess QoL. A good assessment of QoL and better understanding of PMD as a disease that affects multiple aspects of patients' lives will aid in treatment of this condition
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    • Löwe B, Spitzer RL, Williams JBW, et al. Depression, anxiety and somatization in primary care: syndrome overlap and functional impairment. Gen Hosp Psychiatry 2008; 30:191-199. In a large primary care study in the United States, 2091 consecutive patients participated in a cross-sectional survey in 15 clinics (participation rate, 92%). Depression, anxiety, somatization and functional impairment were assessed using validated scales from the Patient Health Questionnaire (PHQ) (PHQ-8, eight-item depression module; GAD-7, seven-item Generalized Anxiety Disorder Scale; and PHQ-15, 15-item somatic symptom scale) and the SF20). Multiple linear regression analyses were used to investigate unique and overlapping associations of depression, anxiety and somatization with functional impairment. Each of the syndromes was associated with substantial reductions in all areas of QoL. Each of the three syndromes had unique and independent associations with at least four of the six SF20 scales, although the unique contribution of each syndrome to QoL was small to moderate.


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