Columnar cell lesions of the breast: An update and significance on core biopsy

Pathology

Volumn 41, Issue 1, 2009, Pages 18-27

  Jara Lazaro, Ana Richelia ^a   Tse, Gary Man Kit ^b   Tan, Puay Hoon ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Atypical ductal hyperplasia; Core biopsy; Flat epithelial atypia; Lobular neoplasia

Indexed keywords

BREAST BIOPSY; BREAST LESION; CALCIFICATION; CANCER INCIDENCE; CANCER SCREENING; CARCINOMA IN SITU; CELL DAMAGE; CELL HYPERPLASIA; CLINICAL FEATURE; COLUMNAR EPITHELIUM; EPITHELIUM CELL; HUMAN; LUNG CARCINOMA; MORPHOLOGY; NOMENCLATURE; REVIEW;

EID: 57749117159     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1080/00313020802563486     Document Type: Article

References (57)

1. Polyak K. On the birth of breast cancer. Biochim Biophys Acta 2001; 1552: 1-13.
2. Ho BC, Tan PH. Flat epithelial atypia: concepts and controversies of an intraductal lesion of the breast. Pathology 2005; 37: 105-11.
3. Ellis IO, Pinder SE, Bobrow L, et al. Pathology Reporting of Breast Disease. NHS Publication no. 58. Sheffield, UK: NHS, 2005; 37-40.
4. Rosen PP. Ductal hyperplasia. In: Rosen PP. Rosen's Breast Pathology. Philadelphia: Lippincott Williams and Wilkins, 2009; 230-63.
5. Page DL, Anderson TJ. Diagnostic Histopathology of the Breast. Edinburgh: Churchill Livingstone, 1987; 86-8.
6. Fraser JL, Raza S, Chorny K, Connolly JL, Schnitt SJ. Columnar alteration with prominent apical snouts and secretions: A spectrum of changes frequently present in breast biopsies performed for microcalcifications. Am J Surg Pathol 1998; 22: 1521-7.
7. Kasami M, Jensen Ra, Simpson JF, Page DL. Lobulocentricity of breast hypersecretory hyperplasia with cytologic atypia: infrequent association with carcinoma in situ. Am J Clin Pathol 2004; 122: 714-20.
8. Wellings SR, Jensen HM, Marcum RG. An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst 1975; 55: 231-73.
9. Kusama R, Fujimori M, Matsuyama I, et al. Clinicopathological characteristics of atypical cystic duct (ACD) of the breast: assessment of ACD as a precancerous lesion. Pathol Int 2000; 50: 793-800.
10. Goldstein NS, O'Malley BS. Cancerization of small ectatic ducts lined by atypical duct cells with apocrine snouts. a lesion associated with tubular carcinoma. Am J Clin Pathol 1997; 107: 561-6.
11. Martel M, Barron-Rodriguez P, Tolgay Ocal I, Dotto J, Tavassoli FA. Flat DIN1 (flat epithelial atypia) on core needle biopsy: 63 cases identified retrospectively among 1751 core biopsies performed over an 8-year period (1992-1999). Virchows Arch 2007; 451: 883-91.
12. De Potter CR, Foschini MP, Schelfhout AM, Schroeter C, Eusebi V. Immunohistochemical study of neu protein overexpression in clinging in situ duct carcinoma of the breast. Virchows Arch A Pathol Anat Histopathol 1997; 422: 375-80.
13. Koerner FC, Oyama T, Maluf H. Morphological observations regarding the origin of atypical cystic lobules (low-grade clinging carcinoma of flat type). Virchows Arch 2001; 439: 523-30.
14. Schnitt SJ. Columnar cell lesions of the breast: pathological features and clinical significance. Curr Diagn Pathol 2004; 10: 193-203.
15. Schnitt SJ. Flat epithelial atypia - classification, pathologic features and clinical significance. Breast Cancer Res 2003; 5: 263-8.
16. Feeley L, Quinn CM. Columnar cell lesions of the breast. Histopathology 2008; 52: 11-9.
17. Simpson PT, Gale T, Reis-Filho JS, et al. Columnar cell lesions of the breast: the missing link in breast cancer progression? A morphological and molecular analysis. Am J Surg Pathol 2005; 29: 734-46.
18. Tavassoli FA, Hoefler H, Rosai J, et al. Intraductal proliferative lesions. In: Tavassoli, FA, Devilee, P, editors. Pathology and Genetics: Tumours of the Breast and Female Genital Organs. Lyon: IARC Press, 2003; 63-73.
19. Abdel-Fatah T, Powe D, Hodi, Z, Lee A, Reis-Filho J, Ellis I. High frequency of coexistence of columnar cell lesions, lobular neoplasia and lowgrade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma. Am J Surg Pathol 2007; 31: 417-26.
20. Collins LC, Achacolso NA, Nedhlyudov L, et al. Clinical and pathologic features of ductal carcinoma in situ associated with the presence of flat epithelial atypia: an analysis of 543 patients. Mod Pathol 2007; 20: 1149-55.
21. Simooka H, Oyama T, Sano T, Horiguchi J, Nakajima T. Immunohistochemical analysis of 14-3-3 sigma and related proteins in hyperplastic and neoplastic breast lesions, with particular reference to early carcinogenesis. Pathol Int 2004; 54: 595-602.
22. Nasser SM. Columnar cell lesions: Current classification and controversies. Semin Diagn Pathol 2004; 21: 18-24.
23. Oyama T, Iijima K, Takei H, et al. Atypical cystic lobule of the breast: an early stage of low-grade ductal carcinoma in situ. Breast Cancer 2000; 7: 326-31.
24. Oyama T, Maluf H, Koerner F. Atypical cystic lobules: an early stage in the formation of low-grade ductal carcinoma in situ. Virchows Arch 1999; 435: 413-21.
25. Sahoo S. Triad of columnar cell alteration, lobular carcinoma in situ, and tubular carcinoma of the breast. Breast J 2005; 11: 140-2.
26. Guerra-Wallace MM, Christensen WN, White RL. A retrospective study of columnar alteration with prominent apical snouts and secretions and the association with cancer. Am J Surg 2004; 188: 395-8.
27. Dessauvagie BF, Zhao WZ, Heel-Miller KA, Harvey J, Bentel JM. Characterization of columnar cell lesions of the breast: Immunophenotypic analysis of columnar alteration of lobules with prominent apical snouts and secretions. Hum Pathol 2007; 38: 284-92.
28. Pinder SE, Provenzano E, Reis-Filho JS. Lobular in situ neoplasia and columnar cell lesions: diagnosis in breast core biopsies and implications for management. Pathology 2007; 39: 208-16.
29. Mclaren VK, Gobbi H, Schuyler PA, et al. Immunohistochemical expression of estrogen receptor in enlarged lobular units with columnar alteration in breast biopsies: A nested case-control study. Am J Surg Pathol 2005; 29: 105-8.
30. Tremblay G, Deschenes J, Alpert L, Quenneville LA. Overexpression of estrogen receptors in columnar cell change and in unfolding breast lobules. Breast J 2005; 11: 326-32.
31. Noel JC, Fayt I, Fernandez-Aguilar S, Buxant F, Boutemy R. Proliferating activity in columnar cell lesions of the breast. Virchows Arch 2006; 449: 617-21.
32. Moinfar F, Man Y-G, Bratthauer GL, Ratschek M, Tavassoli FA. Genetic abnormalities in mammary ductal intraepithelial neoplasia-flat type ('Clinging ductal carcinoma in situ'). Cancer 2000; 88: 2072-81.
33. Dabbs DJ, Carter G, Fundge M, Peng Y, Swalsky P, Finkeltein S. Molecular alterations in columnar cell lesions of the breast. Mod Pathol 2006; 19: 344-9.
34. Kunju LP, Kleer CG. Significance of flat epithelial atypia on mammotome core needle biopsy: should it be excised? Hum Pathol 2007; 38: 35-41.
35. Eusebi V, Feudale E, Foschini MP, et al. Long-term follow-up of in situ carcinoma of the breast. Semin Diagn Pathol 1994; 11: 223-35.
36. Kim MJ, Kim K-K, Oh KK, Park BW, Kim H. Columnar cell lesions of the breast: Mammographic and US features. Eur J Radiol 2006; 60: 264-9.
37. Lerwill MF. Flat epithelial atypia of the breast. Arch Pathol Lab Med 2008; 132: 614-21.
38. Pinder SE, Reis-Filho JS. Non-operative breast pathology: Columnar cell lesions. J Clin Pathol 2007; 60: 1307-12.
39. Lim CN, Ho BCS, Bay BH, Yip G, Tan PH. Nuclear morpholometry in columnar cell lesions of the breast: Is it useful? J Clin Pathol 2006; 59: 1283-6.
40. Bonnett M, Wallis T, Rossmann M, et al. Histopathologic analysis of atypical lesions in image-guided core breast biopsies. Mod Pathol 2003; 16: 154-60.
41. MacGrogan G, Arnould L, de Mascarel I, et al. Impact of immunohistochemical markers, CK5/6 and E-cadherin on diagnostic agreement in non-invasive proliferative breast lesions. Histopathology 2008; 52: 689-97.
42. Tan PH, Ho BC-S, Selvarajan S, Yap WM, Hanby A. Pathological diagnosis of columnar cell lesions of the breast: Are there issues of reproducibility? J Clin Pathol 2005; 58: 705-9.
43. O'Malley FP, Mohsin SK, Badve S, et al. Interobserver reproducibility in the diagnosis of flat epithelial atypia of the breast. Mod Pathol 2006; 19: 172-9.
44. Labbe-Devilliers DN, Moreau C, Loussouarn D, Campion L. Diagnosis of flat epithelial atypia after stereotactic vacuum-assisted biopsy of the breast: What is the best management: systematic surgery for all or follow up? Clinical Imaging 2007; 31: 220-223 (Abstr).
45. Adrales G, Turk P, Wallace T, Bird R, Norton J, Greene F. Is surgical excision necessary for atypical ductal hyperplasia of the breast diagnosed by mammotome? Am J Surg 2000; 180: 313-5.
46. Doren E, Hulvat M, Norton J, et al. Predicting cancer on excision of atypical ductal hyperplasia. Am J Surg 2008; 195: 358-62.
47. Lieske B, Ravichandran D, Alvi A, Lawrence DAS, Wright DJ. Screen-detected breast lesions with an indeterminate (B3) core needle biopsy should be excised. Eur J Surg Oncol 2008; 34: 1293-8.
48. Rao A, Parker S, Ratzer E, Stephens J, Fenoglio M. Atypical ductal hyperplasia of the breast diagnosed by 11-guage directional vacuum-assisted biopsy. Am J Surg 2002; 184: 534-7.
49. Ho JT-S, Tan PH, Hee, S-W, Wong JS-L. Underestimation of malignancy of atypical ductal hyperplasia diagnosed on 11-guage stereotactically guided mammotome breast biopsy: An Asian breast screen experience. Breast 2008; 17: 401-6.
50. Margenthaler JA, Duke D, Monsees BS, Barton PT, Clark C, Dietz JR. Correlation between core biopsy and excisional biopsy in breast high-risk lesions. Am J Surg 2006; 192: 534-7.
51. Bedei L, Falcini F, Casadei G, et al. Atypical ductal hyperplasia of the breast: The controversial management of a borderline lesion: Experience of 47 cases diagnosed at vacuum-assisted biopsy. Breast 2006; 15: 196-202.
52. Sneige N, Lim SC, Whitman GJ, et al. Atypical ductal hyperplasia by directional vacuum-assisted stereotactic biopsy of breast microcalcifications. Considerations for surgical excision. Am J Clin Pathol 2003; 119: 248-53.
53. Jacobs TW, Connolly JL, Schnitt SJ. Nonmalignant lesions in breast core needle biopsies: to excise or not to excise? Am J Surg Pathol 2002; 26: 1095-110.
54. Cox D, Bradley S, England D. The significance of mammotome core biopsy specimens without radiographically identifiable microcalcification and their influence on surgical management - A retrospective review with histological correlation. Breast 2006; 15: 210-8.
55. Linda A, Zuiani C, BazzocchiM, Furlan A, LonderoV. Borderline breast lesions diagnosed at core needle biopsy: Can magnetic resonance mammography rule out associated malignancy? Preliminary results based on 79 surgically excised lesions. Breast 2008; 17: 125-31.
56. Sardanelli F. Houssami N. Evaluation of lesions of uncertain malignant potential (B3) at core needle biopsy using magnetic resonance imaging: A new approach warrants prospective studies. Breast 2008; 17: 117-9.
57. Maganini RO, Klem DA, Huston BJ, Bruner E, Jacobs HK. Upgrade rate of core biopsy-determined atypical ductal hyperplasia by open excisional biopsy. Am J Surg 2001; 182: 355-8.