Characterization of human Mucin (MUC15) and identification of ovine and caprine orthologs

Journal of Dairy Science

Volumn 91, Issue 12, 2008, Pages 4477-4483

  Pallesen, L T ^a   Pedersen, L R L ^a   Petersen, T E ^a   Knudsen, C R ^a   Rasmussen, J T ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Milk fat globule membrane; MUC15; Mucin expression; Ortholog

Indexed keywords

BOVINAE; CAPRA; OVIS; SUS;

EID: 57749115701     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2008-1204     Document Type: Article

References (18)

1. Baldus, S. E., K. Engelmann, and F. G. Hanisch. 2004. MUC1 and the MUCs: A family of human mucins with impact in cancer biology. Crit. Rev. Clin. Lab. Sci. 41:189-231.
2. Benfeldt, C., L. B. Larsen, J. T. Rasmussen, P. A. Andreasen, and T. E. Petersen. 1995. Isolation and characterization of plasminogen and plasmin from bovine milk. Int. Dairy J. 5:517-592.
3. Blom, N., S. Gammeltoft, and S. Brunak. 1999. Sequence- and structure-based prediction of eukaryotic protein phosphorylation sites. J. Mol. Biol. 294:1351-1362.
4. Corrales, R. M., D. J. Galarreta, J. M. Herreras, M. Calonge, and F. J. Chaves. 2003. Normal human conjunctival epithelium expresses MUC13, MUC15, MUC16 and MUC17 mucin genes. Arch. Soc. Esp. Oftalmol. 78:375-381.
5. Devold, T. G., M. Rykke, D. Isabey, E. S. Sorensen, B. Christensen, T. Langsrud, C. Svenning, B. Borch-Iohnsen, J. Karlsen, and G. E. Vegarud. 2006. In vitro studies of adsorption of milk proteins onto tooth enamel. Int. Dairy J. 16:1013-1017.
6. Gendler, S. J. 2001. MUC1, the renaissance molecule. J. Mammary Gland Biol. Neoplasia 6:339-353.
7. Hollingsworth, M. A., and B. J. Swanson. 2004. Mucins in cancer: Protection and control of the cell surface. Nat. Rev. Cancer 4:45-60.
8. Hung, A. Y., and M. Sheng. 2002. PDZ domains: Structural modules for protein complex assembly. J. Biol. Chem. 277:5699-5702.
9. Hvarregaard, J., M. H. Andersen, L. Berglund, J. T. Rasmussen, and T. E. Petersen. 1996. Characterization of glycoprotein PAS-6/7 from membranes of bovine milk fat globules. Eur. J. Biochem. 240:628-636.
10. Kessels, H. W., A. C. Ward, and T. N. M. Schumacher. 2002. Specificity and affinity motifs for Grb2 SH2-ligand interactions. Proc. Natl. Acad. Sci. USA 99:8524-8529.
11. Li, Y., J. Ren, W. Yu, Q. Li, H. Kuwahara, L. Yin, K. L. Carraway, and D. Kufe. 2001. The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin. J. Biol. Chem. 276:35239-35242.
12. Meerzaman, D., P. S. Shapiro, and K. C. Kim. 2001. Involvement of the MAP kinase ERK2 in MUC1 mucin signaling. Am. J. Physiol. Lung Cell. Mol. Physiol. 281:L86-L91.
13. Pallesen, L. T., L. Berglund, L. K. Rasmussen, T. E. Petersen, and J. T. Rasmussen. 2002. Isolation and characterization of MUC15, a novel cell membrane-associated mucin. Eur. J. Biochem. 269:2755-2763.
14. Pallesen, L. T., L. R. L. Pedersen, T. E. Petersen, and J. T. Rasmussen. 2007. Characterization of carbohydrate structures of bovine MUC15 and distribution of the mucin in bovine milk. J. Dairy Sci. 90:3143-3152.
15. Patton, S. 2001. MUC1 and MUC-X, epithelial mucins of breast and milk. Adv. Exp. Med. Biol. 501:35-45.
16. Shimizu, M., and K. Yamauchi. 1982. Isolation and characterization of mucin-like glycoprotein in human milk fat globule membrane. J. Biochem. 91:515-524.
17. Shyu, M. K., M. C. Lin, J. C. Shih, C. N. Lee, J. Huang, C. H. Liao, I. F. Huang, H. Y. Chen, M. C. Huang, and F. J. Hsieh. 2007. Mucin 15 is expressed in human placenta and suppresses invasion of trophoblast-like cells in vitro. Hum. Reprod. 22:2723-2732.
18. Zhang, J., A. Perez, M. Yasin, P. Soto, M. Rong, G. Theodoropoulos, C. A. Carothers Carraway, and K. L. Carraway. 2005. Presence of MUC4 in human milk and at the luminal surfaces of blood vessels. J. Cell. Physiol. 204:166-177.