Association of smoking behavior with an odorant receptor allele telomeric to the human major histocompatibility complex

Genetic Testing

Volumn 12, Issue 4, 2008, Pages 481-486

  Santos, Pablo Sandro Carvalho ^a   Füst, George ^b   Prohászka, Zoltán ^b,c   Volz, Armin ^a   Horton, Roger ^d   Miretti, Marcos ^d   Yu, Chack Yung ^e   Beck, Stephan ^f   Uchanska Ziegler, Barbara ^a   Ziegler, Andreas ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^e OHIO STATE UNIVERSITY   (United States)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BERGAMOT OIL; GENOMIC DNA; HLA A1 ANTIGEN; HLA B8 ANTIGEN; HLA DR3 ANTIGEN; OR12D3 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; BEHAVIOR; CAUCASIAN; CIGARETTE SMOKING; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE CLUSTER; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HAPLOTYPE; HLA SYSTEM; HUMAN; HUNGARY; LIGAND BINDING; MAJOR HISTOCOMPATIBILITY COMPLEX; ODOR; POPULATION GENETICS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR GENE; SINGLE NUCLEOTIDE POLYMORPHISM; TOBACCO; TOBACCO DEPENDENCE;

ALLELES; COHORT STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HAPLOTYPES; HLA-A1 ANTIGEN; HLA-B8 ANTIGEN; HLA-DR3 ANTIGEN; HUMANS; HUNGARY; LINKAGE DISEQUILIBRIUM; MAJOR HISTOCOMPATIBILITY COMPLEX; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, ODORANT; SMOKING; TELOMERE;

EID: 57749111628     PISSN: 10906576     EISSN: None     Source Type: Journal    
DOI: 10.1089/gte.2008.0029     Document Type: Article

References (43)

1. Abaffy T, Malhotra A, Luetje CW (2007) The molecular basis for ligand specificity in a mouse olfactory receptor: a network of functionally important residues. J Biol Chem 282:1216-1224.
2. Alper CA, Larsen CE, Dubey DP, et al. (2006) The haplotype structure of the human major histocompatibility complex. Hum Immunol 67:73-84.
3. American Cancer Society (2003) 12th World Conference on Tobacco or Health. Tobacco Control Profiles. American Cancer Society, Atlanta.
4. American Cancer Society (2007) Cancer facts and figures 2007. American Cancer Society, Atlanta.
5. Baker RR, Pereira da Silva JR, Smith G (2004) The effect of tobacco ingredients on smoke chemistry. Part I: Flavorings and additives. Food Chem Toxicol 42:S3-S37.
6. Barman SK, Pulkkinen L, Kaprio J, Rose RJ (2004) Inattentiveness, parental smoking and adolescent smoking initiation. Addiction 99:1049-1061.
7. Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265.
8. de Bakker PIW, McVean G, Sabeti PC, et al. (2006) A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet 38:1166-1172.
9. Dyment DA, Ebers GC, Sadovnick AD (2004) Genetics of multiple sclerosis. Lancet Neurol 3:104-110.
10. Ehlers A, Beck S, Forbes SA, et al. (2000) MHC-linked olfactory receptor loci exhibit polymorphism and contribute to extended HLA=OR-haplotypes. Genome Res 10:1968-1978.
11. Franklin TR,Wang Z,Wang J, et al. (2007) Limbic activation to cigarette smoking cues independent of nicotine withdrawal: a perfusion FMRI study. Neuropsychopharmacology 32:2301-2309.
12. Füst G, Arason GJ, Kramer J, et al. (2004) Genetic basis of tobacco smoking: strong association of a specific major histocompatibility complex haplotype on chromosome 6 with smoking behavior. Int Immunol 16:1507-1514.
13. Global Youth Tobacco Survey Collaborating Group (2003) Differences in worldwide tobacco use by gender: findings from the Global Youth Tobacco Survey. J Sch Health 73:207-215.
14. Hawkes CH (2007) Smoking is a risk factor for multiple sclerosis: a metaanalysis. Mult Scler 13:610-615.
15. Hegedius L, Brix TH, Vestergaard P (2004) Relationship between cigarette smoking and Graves' ophthalmopathy. J Endocrinol Invest 27:265-271.
16. Herrera BM, Cader MZ, Dyment DA, et al. (2006) Follow-up investigation of 12 proposed linkage regions in multiple sclerosis. Genes Immun 7:366-371.
17. Holm IA, Manson JE, Michels KB, et al. (2005) Smoking and other lifestyle factors and the risk of Graves' hyperthyroidism. Arch Intern Med 165:1606-1611.
18. Horton R, Wilming L, Rand V, et al. (2004) Gene map of the extended human MHC. Nat Rev Genet 5:889-899.
19. Hunt PJ, Marshall SE, Weetman AP, et al. (2001) Histocompatibility leucocyte antigens and closely linked immunomodulatory genes in autoimmune thyroid disease. Clin Endocrinol 55:491-499.
20. Jarvis MJ (2004) Why people smoke. BMJ 328:277-279.
21. Jordens JZ, Lanham S, Pickett MA, et al. (2000) Amplification with molecular beacon primers and reverse line blotting for the detection and typing of human papillomaviruses. J Virol Meth 89:29-37.
22. Katada S, Hirokawa T, Oka Y, et al. (2005) Structural basis for a broad but selective ligand spectrum of a mouse olfactory receptor: mapping the odorant-binding site. J Neurosci 25:1806-1815.
23. Keller A, Zhuang H, Chi Q, et al. (2007) Genetic variation in a human odorant receptor alters odour perception. Nature 449:468-472.
24. Klareskog L, Stolt P, Lundberg K, et al. (2006) A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination. Arthritis Rheum 54:38-46.
25. Koch M, van Harten A, Uyttenboogaart M, de Keyser J (2007) Cigarette smoking and progression in multiple sclerosis. Neurology 69:1515-1520.
26. Lerer E, Kanyas K, Karni O, et al. (2006) Why do young women smoke? II. Role of traumatic life experience, psychological characteristics and serotonergic genes. Mol Psychiatry 11:771-781.
27. Li MD, Cheng R, Ma JZ, Swan GE (2003) A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction 98:23-31.
28. Linn-Rasker SP, van der Helm-van Mil AHM, van Gaalen FA, et al. (2006) Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles. Ann Rheum Dis 65:366-371.
29. Man O, Gilad Y, Lancet D (2004) Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons. Protein Sci 13:240-254.
30. Milinski M, Wedekind C (2001) Evidence for MHC-correlated perfume preferences in humans. Behav Ecol 12:140-149.
31. Miretti MM, Walsh EC, Ke X, et al. (2005) A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am J Hum Genet 76:634-646.
32. Nei M (1987) Molecular Evolutionary Genetics. Columbia University Press, New York.
33. Palczewski K, Kumasaka T, Hori T, et al. (2000) Crystal structure of rhodopsin: a G protein-coupled receptor. Science 289:739-745.
34. Pomerleau CS, Pomerleau OF, Flessland KA, Basson SM (1992) Relationship of tridimensional personality questionnaire scores and smoking variables in female and male smokers. J Subst Abuse 4:143-154.
35. Rasmussen SGF, Choi H, Rosenbaum DM, et al. (2007) Crystal structure of the human β2 adrenergic G-protein-coupled receptor. Nature 450:383-387.
36. Rozas J, Rozas R (1999) DnaSP version 3: an integrated program for molecular population genetics and molecular evolution analysis. Bioinformatics 15:174-175.
37. Schmiedeberg K, Shirokova E, Weber HP, et al. (2007) Structural determinants of odorant recognition by the human olfactory receptors OR1A1 and OR1A2. J Struct Biol 159:400-412.
38. Sullivan PF, Kendler KS (1999) The genetic epidemiology of smoking. Nicotine Tob Res 1:S51-S59.
39. Warren CW, Jones NR, Eriksen MP, Asma S (2006) Global Tobacco Surveillance System (GTSS) collaborative group: patterns of global tobacco use in young people and implications for future chronic disease burden in adults. Lancet 367:749-753.
40. Weetman AP (2000) Graves' disease. N Engl JMed 343:1236-1248.
41. Younger RM, Amadou C, Bethel G, et al. (2001) Characterization of clustered MHC-linked olfactory receptor genes in human and mouse. Genome Res 11:519-530.
42. Zhao Z, Fu YX, Hewett-Emmett D, Boerwinkle E (2003) Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution. Gene 312:207-213.
43. Ziegler A, Uchańska-Ziegler B (2006) Rheumatoid arthritis etiology and HLA-linked odorant receptor gene polymorphisms: comment on the article by Klareskog et al. Arthritis Rheum 54:2705-2706.