Synthesis and structure-activity studies of novel homomorpholine oxazolidinone antibacterial agents

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 2, 2009, Pages 550-553

  Kim, Ji Young ^a   Boyer, Frederick E ^a   Choy, Allison L ^a   Huband, Michael D ^a   Pagano, Paul J ^a   Vara Prasad, J V N ^a  

^a PFIZER INC   (United States)

Author keywords

Antibacterial agents; Gram positive; Homomorpholine; Linezolid; Oxazolidinone; Structure activity relations; Synthesis of analogs

Indexed keywords

ACETAMIDE DERIVATIVE; AMIDE; ANTIINFECTIVE AGENT; HOMOMORPHOLINE OXAZOLIDINONE DERIVATIVE; LINEZOLID; OXAZOLIDINONE DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SUBSTITUTION REACTION;

ANTI-BACTERIAL AGENTS; MORPHOLINES; OXAZOLIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

POSIBACTERIA;

EID: 57749106144     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.02.052     Document Type: Article

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