The catalytic activity of protein-disulfide isomerase requires a conformationally flexible molecule

Journal of Biological Chemistry

Volumn 283, Issue 48, 2008, Pages 33630-33640

  Tian, Geng ^a   Kober, Franz Xaver ^b   Lewandrowski, Urs ^b   Sickmann, Albert ^b   Lennarz, William J ^a   Schindelin, Hermann ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASSOCIATION REACTIONS; CATALYST ACTIVITY; CELL MEMBRANES; COVALENT BONDS; DIMERS; ENZYME ACTIVITY; MOLECULES; SULFUR COMPOUNDS;

CONFORMATIONAL CHANGE; ENDOPLASMIC RETICULUM; ENZYMATIC ACTIVITIES; FLEXIBLE MOLECULES; GREEN FLUORESCENT PROTEIN; LIMITED PROTEOLYSIS; MOLECULAR FLEXIBILITY; PROTEIN DISULFIDE ISOMERASES;

CRYSTAL STRUCTURE;

PROTEIN DISULFIDE ISOMERASE;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; DISULFIDE BOND; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME BINDING; ENZYME DEGRADATION; ENZYME MECHANISM; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; ROOM TEMPERATURE;

EID: 57749102824     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M806026200     Document Type: Article

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