Re-evaluation of an animal model for ADHD using a free-operant choice task

Journal of Neuroscience Methods

Volumn 176, Issue 2, 2009, Pages 166-171

  Pardey, Margery C ^a   Homewood, Judi ^a   Taylor, Alan ^a   Cornish, Jennifer L ^a  

^a MACQUARIE UNIVERSITY   (Australia)

Author keywords

Animal model; Attention Deficit Hyperactivity Disorder; Delayed reinforcement; Locomotor activity; Spontaneously Hypertensive Rat

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENTION DEFICIT DISORDER; CONTROLLED STUDY; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; REINFORCEMENT; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

ANALYSIS OF VARIANCE; ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CHOICE BEHAVIOR; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; EVALUATION STUDIES AS TOPIC; EXTINCTION, PSYCHOLOGICAL; MALE; MOTOR ACTIVITY; NEUROPSYCHOLOGICAL TESTS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; REINFORCEMENT (PSYCHOLOGY); TIME FACTORS;

EID: 57749098654     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2008.09.009     Document Type: Article

References (26)

1. Alsop B. Problems with spontaneously hypertensive rats (SHR) as a model of Attention-Deficit/Hyperactivity Disorder (AD/HD). J Neurosci Meth 162 (2007) 42-48
2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed., text revision ed. (2000), American Psychiatric Association, Washington, DC
3. Berger D., and Sagvolden T. Sex differences in operant discrimination behaviour in an animal model of Attention-Deficit Hyperactivity Disorder. Behav Brain Res 94 (1998) 73-82
4. Biederman J., Faranone S.V., Keenan K., Knee D., and Tsuang M.T. Family-genetic and psychosocial risk factors in DSM-III Attention-Deficit Disorder. J Am Acad Child Adolesc Psychiatry 29 (1990) 526-533
5. Boix F., Qiao S., Kolpus T., and Sagvolden T. Chronic l-deprenyl treatment alters brain monoamine levels and reduces impulsiveness in an animal model of Attention-Deficit/Hyperactivity Disorder. Behav Brain Res 94 (1998) 153-162
6. Bucci D.J., Hopkins M.E., Keene C.S., Sharma M., and Orr L.E. Sex differences in learning and inhibition in spontaneously hypertensive rats. Behav Brain Res 187 (2008) 27-32
7. Cook E.H.J., Stein M.A., Krasowski M.D., Cox N.J., Olkon D.M., Kieffer J.E., et al. Associations of Attention-Deficit Disorder and the dopamine transporter gene. Am J Hum Genet 56 (1995) 993-998
8. Davids E., Zhang K., Tarazi F.I., and Baldessarini R.J. Animal models of Attention-Deficit Hyperactivity Disorder. Brain Res Rev 42 (2003) 1-21
9. Drolet G., Proulx K., Pearson D., Rochford J., and Deschepper C.F. Comparisons of behavioral and neurochemical characteristics between WKY, WKHA, and Wistar rat strains. Neuropsychopharmacology 27 (2002) 400-409
10. Evenden J.L., and Ryan C.N. The pharmacology of impulsive behaviour in rats: the effects of drugs on response choice with varying delays of reinforcement. Psychopharmacology 128 (1996) 161-170
11. Fox A.T., Hand D.J., and Reilly M.P. Impulsive choice in a rodent model of Attention-Deficit/Hyperactivity Disorder. Behav Brain Res 187 (2008) 146-152
12. Johansen E.B., and Sagvolden T. Behavioral effects of intra-cranial self-stimulation in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD). Behav Brain Res 162 (2005) 32-46
13. Johansen E.B., Aase H., Meyer A., Sagvolden T., and Attention-Deficit/Hyperactivity Disorder (ADHD) behavior explained by dysfunctioning reinforcement and extinction processes. Behav Brain Res 130 (2002) 37-45
14. Johansen E.B., Sagvolden T., and Kvande G. Effects of delayed reinforcers on the behavior of an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD). Behav Brain Res 162 (2005) 47-61
15. Johansen E.B., Killeen P.R., and Sagvolden T. Behavioral variability, elimination of responses, and delay-of-reinforcement gradients in SHR and WKY rats. Behav Brain Funct 3 (2007) 60-90
16. Mook D.M., Jeffrey J., and Neuringer A. Spontaneously hypertensive rats (SHR) readily learn to vary but not repeat instrumental responses. Behav Neural Biol 59 (1993) 126-135
17. National Health and Medical Research Council. Australian code of practice for the care and use of animals for scientific purposes, 7th ed. 2004.
18. Sagvolden T. Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of Attention-Deficit/Hyperactivity Disorder (AD/HD). Neurosci Biobehav Rev 24 (2000) 31-39
19. Sagvolden T., Metzger M.A., Schiorbeck H.K., Rugland A.-L., Spinnangr I., and Sagvolden G. The spontaneously hypertensive rat (SHR) as an animal model of childhood hyperactivity (ADHD): changed reactivity to reinforcers and to psychomotor stimulants. Behav Neural Biol 58 (1992) 103-112
20. Sagvolden T., Petterson M.B., and Larsen M.C. Spontaneously hypertensive rats (SHR) as a putative animal model of childhood hyperkinesis: SHR behavior compared to four other rat strains. Physiol Behav 54 (1993) 1047-1055
21. Sagvolden T., Aase H., Zeiner P., and Berger D. Altered reinforcement mechanisms in Attention-Deficit/Hyperactivity Disorder. Behav Brain Res 94 (1998) 61-71
22. Sagvolden T., Russell V.A., Aase H., Johansen E.B., and Farshbaf M. Rodent models of Attention-Deficit/Hyperactivity Disorder. Biol Psychiatry 57 (2005) 1239-1247
23. Sonuga-Barke E.J.S., Taylor E., Sembi S., and Smith J. Hyperactivity and delay aversion. I. The effect of delay on choice. J Child Psychol Psychiatry 33 (1992) 387-398
24. Tannock R. Attention Deficit Hyperactivity Disorder: advances in cognitive, neurobiological and genetic research. J Child Psychol Psychiatry 39 (1998) 65-99
25. van den Bergh F.S., Bloemarts E., Chan J.S.W., Groenink L., Olivier B., and Oosting R.S. Spontaneously hypertensive rats do not predict symptoms of Attention-Deficit Hyperactivity Disorder. Pharmacol Biochem Behav 83 (2006) 380-390
26. Volkow N.D., Wang G., Fowler J.S., Logan J., Gerasimov M., Maynard L., et al. Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain. J Neurosci 21 (2001) RC121