Preparation of new 2-amino- and 2,3-diamino-pyridine trifluoroacetyl enamine derivatives and their application to the synthesis of trifluoromethyl-containing 3H-pyrido[2,3-b][1,4] diazepinols

Journal of Heterocyclic Chemistry

Volumn 45, Issue 6, 2008, Pages 1679-1686

  Bonacorso, Helio G ^a   Lourega, Rogério V ^a   Righi, Fernando J ^a   Deon, Everton D ^a   Zanatta, Nilo ^a   Martins, Marcos A P ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 BROMOPHENYL) 4 TRIFLUOROMETHYL 4,5 DIHYDRO 3H PYRIDO[2,3 BETA]DIAZEPIN 4 OL; 2 (4 CHLOROPHENYL) 4 TRIFLUOROMETHYL 4,5 DIHYDRO 3H PYRIDO[2,3 BETA]DIAZEPIN 4 OL; 2 (4 FLUOROPHENYL) 4 TRIFLUOROMETHYL 4,5 DIHYDRO 3H PYRIDO[2,3 BETA]DIAZEPIN 4 OL; 2 (4 METHOXYPHENYL) 4 TRIFLUOROMETHYL 4,5 DIHYDRO 3H PYRIDO[2,3 BETA]DIAZEPIN 4 OL; 2 (4 METHYLPHENYL) 4 TRIFLUOROMETHYL 4,5 DIHYDRO 3H PYRIDO[2,3 BETA]DIAZEPIN 4 OL; 2 (4,4' BIPHENYL) 4 TRIFLUOROMETHYL 4,5 DIHYDRO 3H PYRIDO[2,3BETA]DIAZEPIN 4 OL; 2 PHENYL 4 TRIFLUOROMETHYL 4,5 DIHYDRO 3H PYRIDO[2,3BETA]DIAZEPIN 4 OL; ENAMINE; N 3 [1 (1 NAPHTHYL) 3 OXO 4,4,4 TRIFLUOROPENT 1 EN 1 YL] 2,3 DIAMINOPYRIDINE; N 3 [1 (2 THIENYL) 3 OXO 4,4,4 TRIFLUOROPENT 1 EN 1 YL] 2,3 DIAMINOPYRIDINE; N 3 [1 (4 FLUOROPHENYL) 3 OXO 4,4,4 TRIFLUOROPENT 1 EN 1 YL] 2,3 DIAMINOPYRIDINE; N 3 [1 (4 METHOXYPHENYL) 3 OXO 4,4,4 TRIFLUOROPENT 1 EN 1 YL] 2,3 DIAMINOPYRIDINE; N 3 [1 (4 METHYLPHENYL) 3 OXO 4,4,4 TRIFLUOROPENT 1 EN 1 YL] 2,3 DIAMINOPYRIDINE; N 3 [1 PHENYL 3 OXO 4,4,4 TRIFLUOROPENT 1 EN 1 YL] 2,3 DIAMINOPYRIDINE; N 3 [2 METHYL 5 OXO 6,6,6 TRIFLUOROPENT 3 EN 3 YL] 2,3 DIAMINOPYRIDINE; N 3 [2 METHYL 6 OXO 7,7,7 TRIFLUOROPENT 4 EN 4 YL] 2,3 DIAMINOPYRIDINE; N 3 [2 METHYL 7 OXO 8,8,8 TRIFLUOROPENT 5 EN 5 YL] 2,3 DIAMINOPYRIDINE; N 3 [3 OXO 4,4,4 TRIFLUOROPENT 2 EN 2 YL] 2,3 DIAMINOPYRIDINE; N 3 [6 OXO 7,7,7 TRIFLUOROPENT 4 EN 4 YL] 2,3 DIAMINOPYRIDINE; N 3 [9 OXO 10,10,10 TRIFLUOROPENT 7 EN 7 YL] 2,3 DIAMINOPYRIDINE; N [1 (4 BROMOPHENYL) 3 OXO 4,4,4 TRIFLUOROBUT 1 EN 1 YL] 2 AMINOPYRIDINE; N [1 (4 CHLOROPHENYL) 3 OXO 4,4,4 TRIFLUOROBUT 1 EN 1 YL] 2 AMINOPYRIDINE; N [1 (4 FLUOROPHENYL) 3 OXO 4,4,4 TRIFLUOROBUT 1 EN 1 YL] 2 AMINOPYRIDINE; N [1 (4 METHOXYPHENYL) 3 OXO 4,4,4 TRIFLUOROBUT 1 EN 1 YL] 2 AMINOPYRIDINE; N [1 (4 METHYLPHENYL) 3 OXO 4,4,4 TRIFLUOROBUT 1 EN 1 YL] 2 AMINOPYRIDINE; N [1 PHENYL 3 OXO 4,4,4 TRIFLUOROBUT 1 EN 1 YL] 2 AMINOPYRIDINE; N [3 OXO 4,4,4 TRIFLUOROBUT 1 EN 1 YL] 2 AMINOPYRIDINE; N [4 OXO 5,5,5 TRIFLUOROBUT 2 EN 2 YL] 2 AMINOPYRIDINE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; NUCLEAR MAGNETIC RESONANCE; POLYMERIZATION; SYNTHESIS;

EID: 57749083378     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570450619     Document Type: Article

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40. Crystallographic data for compound 3i, reported in this paper, have been deposited with the Cambridge Crystallographic Data Center (CCDC 687400). Copies of the data can be obtained, free of charge, on application to CCDC 12 Union Road, Cambridge CB2 1EZ, UK (Fax: +44-1223-336033 or e-mail: deposit@ccdc.cam.ac.uk).