메뉴 건너뛰기




Volumn 33, Issue 11, 2008, Pages 642-651

Heparin-induced thrombocytopenia: Overview and treatment

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; ANTIDIABETIC AGENT; ANTIINFLAMMATORY AGENT; ANTIVITAMIN K; ARGATROBAN; CARDIOVASCULAR AGENT; CEPHALOSPORIN; CHLORPROPAMIDE; DANAPAROID; DIAZEPAM; DIGOXIN; FONDAPARINUX; HEPARIN; HIRULOG; LEPIRUDIN; LOW MOLECULAR WEIGHT HEPARIN; METHYLDOPA; PARACETAMOL; PENICILLIN G; PHENYTOIN; QUINIDINE; SEDATIVE AGENT; SULFONAMIDE; THIAZIDE DIURETIC AGENT; TOLBUTAMIDE; TRIMETHOPRIM; UNINDEXED DRUG; VALPROIC ACID;

EID: 57649239085     PISSN: 10521372     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (39)
  • 1
    • 33847388520 scopus 로고    scopus 로고
    • Drug-induced immune-mediated thrombocytopenia: From purpura to thrombosis
    • Warkentin TE. Drug-induced immune-mediated thrombocytopenia: From purpura to thrombosis. N Engl J Med 2007;356(9):891-893.
    • (2007) N Engl J Med , vol.356 , Issue.9 , pp. 891-893
    • Warkentin, T.E.1
  • 2
    • 33746637378 scopus 로고    scopus 로고
    • Heparin and low molecular weight heparins
    • Bick RL, ed, 3rd ed. Philadelphia: Lippincott Williams & Wilkins;
    • Bick RL. Heparin and low molecular weight heparins. In: Bick RL, ed. Disorders of Thrombosis and Hemostasis, 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2006:359-378.
    • (2006) Disorders of Thrombosis and Hemostasis , pp. 359-378
    • Bick, R.L.1
  • 3
    • 33846514264 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia, a prothrombotic disease
    • Levy JH, Hursting MJ. Heparin-induced thrombocytopenia, a prothrombotic disease. Hematol Oncol Clin North Am 2007;21(1):65-88.
    • (2007) Hematol Oncol Clin North Am , vol.21 , Issue.1 , pp. 65-88
    • Levy, J.H.1    Hursting, M.J.2
  • 4
    • 0034235911 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: New evidence for the dynamic binding of purified anti-PF4-heparin antibodies to platelets and the resultant platelet activation
    • Newman PM, Chong BH. Heparin-induced thrombocytopenia: New evidence for the dynamic binding of purified anti-PF4-heparin antibodies to platelets and the resultant platelet activation. Blood 2000;96(1):182-187.
    • (2000) Blood , vol.96 , Issue.1 , pp. 182-187
    • Newman, P.M.1    Chong, B.H.2
  • 5
    • 19644398319 scopus 로고    scopus 로고
    • When heparins promote thrombosis: Review of heparin-induced thrombocytopenia
    • Jang IK, Hursting MJ. When heparins promote thrombosis: Review of heparin-induced thrombocytopenia. Circulation 2005;111(20):2671-2683.
    • (2005) Circulation , vol.111 , Issue.20 , pp. 2671-2683
    • Jang, I.K.1    Hursting, M.J.2
  • 6
    • 0035883078 scopus 로고    scopus 로고
    • Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8
    • Arepally GM, Mayer IM. Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8. Blood 2001;98:1252-1254.
    • (2001) Blood , vol.98 , pp. 1252-1254
    • Arepally, G.M.1    Mayer, I.M.2
  • 7
    • 0023109003 scopus 로고
    • Immune endothelial-cell injury in heparin-associated thrombocytopenia
    • Cines DB, Tomaski A, Tannenbaum S. Immune endothelial-cell injury in heparin-associated thrombocytopenia. N Engl J Med 1987;316:581-589.
    • (1987) N Engl J Med , vol.316 , pp. 581-589
    • Cines, D.B.1    Tomaski, A.2    Tannenbaum, S.3
  • 8
    • 6344281156 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Myths and misconceptions (that will cause trouble for you and your patient)
    • Rice L. Heparin-induced thrombocytopenia: Myths and misconceptions (that will cause trouble for you and your patient). Arch Intern Med 2004;164:1961-1964.
    • (2004) Arch Intern Med , vol.164 , pp. 1961-1964
    • Rice, L.1
  • 9
    • 0037948571 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia
    • Warkentin TE. Heparin-induced thrombocytopenia. Curr Hematol Rep 2002;1:63-72.
    • (2002) Curr Hematol Rep , vol.1 , pp. 63-72
    • Warkentin, T.E.1
  • 10
    • 0035953702 scopus 로고    scopus 로고
    • Temporal aspects of heparin-induced thrombocytopenia
    • Warkentin TE, Kelton JG. Temporal aspects of heparin-induced thrombocytopenia. N Engl J Med 2001;344:1286-1292.
    • (2001) N Engl J Med , vol.344 , pp. 1286-1292
    • Warkentin, T.E.1    Kelton, J.G.2
  • 11
    • 13544251729 scopus 로고    scopus 로고
    • New approaches to the diagnosis of heparin-induced thrombocytopenia
    • Warkentin TE. New approaches to the diagnosis of heparin-induced thrombocytopenia. Chest 2005;127(2 Suppl):35S-45S.
    • (2005) Chest , vol.127 , Issue.2 SUPPL.
    • Warkentin, T.E.1
  • 12
    • 34547099318 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia
    • Warkentin TE. Heparin-induced thrombocytopenia. Hematol Oncol Clin North Am 2007;21(4):589-607.
    • (2007) Hematol Oncol Clin North Am , vol.21 , Issue.4 , pp. 589-607
    • Warkentin, T.E.1
  • 13
    • 45949103154 scopus 로고    scopus 로고
    • Warkentin TE, Greinacher A, Koster A, et al. Treatment and pre-vention of heparin-induced thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines, 8th ed. Chest 2008;133(6 Suppl):340S-380S.
    • Warkentin TE, Greinacher A, Koster A, et al. Treatment and pre-vention of heparin-induced thrombocytopenia: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines, 8th ed. Chest 2008;133(6 Suppl):340S-380S.
  • 14
    • 0035797925 scopus 로고    scopus 로고
    • Delayed-onset heparin-induced thrombocytopenia and thrombosis
    • Warkentin TE, Kelton JG. Delayed-onset heparin-induced thrombocytopenia and thrombosis. Ann Intern Med 2001;135(7):502-506.
    • (2001) Ann Intern Med , vol.135 , Issue.7 , pp. 502-506
    • Warkentin, T.E.1    Kelton, J.G.2
  • 15
    • 0037434883 scopus 로고    scopus 로고
    • Delayed-onset heparin-induced thrombocytopenia and cerebral thrombosis after a single administration of unfractionated heparin
    • Warkentin TE, Bernstein RA. Delayed-onset heparin-induced thrombocytopenia and cerebral thrombosis after a single administration of unfractionated heparin. N Engl J Med 2003;348(11):1067-1069.
    • (2003) N Engl J Med , vol.348 , Issue.11 , pp. 1067-1069
    • Warkentin, T.E.1    Bernstein, R.A.2
  • 16
    • 33644971524 scopus 로고    scopus 로고
    • Evaluation of pretest clinical score (4T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings
    • Lo GK, Juhl D, Warkentin TE, et al. Evaluation of pretest clinical score (4T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb Haemost 2006;4:759-765.
    • (2006) J Thromb Haemost , vol.4 , pp. 759-765
    • Lo, G.K.1    Juhl, D.2    Warkentin, T.E.3
  • 17
    • 21344446637 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Diagnosis and management
    • Warkentin TE. Heparin-induced thrombocytopenia: Diagnosis and management. Circulation 2004;110(18):e454-e458.
    • (2004) Circulation , vol.110 , Issue.18
    • Warkentin, T.E.1
  • 18
    • 0036881566 scopus 로고    scopus 로고
    • Platelet count monitoring and laboratory testing for heparin-induced thrombocytopenia
    • Warkentin TE. Platelet count monitoring and laboratory testing for heparin-induced thrombocytopenia. Arch Pathol Lab Med 2002;126(11):1415-1423.
    • (2002) Arch Pathol Lab Med , vol.126 , Issue.11 , pp. 1415-1423
    • Warkentin, T.E.1
  • 20
    • 57649147374 scopus 로고    scopus 로고
    • Hoffbrand AV, Moss PAH, Pettit JE, eds, 5th ed. Malden, MA: Blackwell;
    • Hoffbrand AV, Moss PAH, Pettit JE, eds. Essential Hematology, 5th ed. Malden, MA: Blackwell; 2006:278-289.
    • (2006) Essential Hematology , pp. 278-289
  • 21
    • 0004544546 scopus 로고    scopus 로고
    • Shinton NK, ed, 2nd ed. Boca Raton, FL: CRC Press;
    • Shinton NK, ed. Desk Reference for Hematology, 2nd ed. Boca Raton, FL: CRC Press; 2008:218.
    • (2008) Desk Reference for Hematology , pp. 218
  • 22
    • 33645446965 scopus 로고    scopus 로고
    • Disorders of the platelet and vessel wall
    • Kasper DL, Braunwald E, Fauchi AS, et al, eds, 16th ed. New York: McGraw-Hill;
    • Hanin RI. Disorders of the platelet and vessel wall. In: Kasper DL, Braunwald E, Fauchi AS, et al., eds. Harrison's Principles of Internal Medicine, 16th ed. New York: McGraw-Hill; 2005:674.
    • (2005) Harrison's Principles of Internal Medicine , pp. 674
    • Hanin, R.I.1
  • 23
    • 34247127070 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia in intensive care patients
    • Selleng K, Warkentin TE, Greinacher A. Heparin-induced thrombocytopenia in intensive care patients. Crit Care Med 2007;35(4):1165-1176.
    • (2007) Crit Care Med , vol.35 , Issue.4 , pp. 1165-1176
    • Selleng, K.1    Warkentin, T.E.2    Greinacher, A.3
  • 24
    • 0030281338 scopus 로고    scopus 로고
    • A 14-year study of heparin-induced thrombocytopenia
    • Warkentin TE, Kelton JG. A 14-year study of heparin-induced thrombocytopenia. Am J Med 1996;101:502-507.
    • (1996) Am J Med , vol.101 , pp. 502-507
    • Warkentin, T.E.1    Kelton, J.G.2
  • 25
    • 33750611336 scopus 로고    scopus 로고
    • Antiplatelet, anticoagulant, and fibrinolytic therapy
    • Kasper DL, Braunwald E, Fauchi AS, et al, eds, 16th ed. New York: McGraw-Hill;
    • Deitcher SRI. Antiplatelet, anticoagulant, and fibrinolytic therapy. In: Kasper DL, Braunwald E, Fauchi AS, et al., eds. Harrison's Principles of Internal Medicine, 16th ed. New York: McGraw-Hill; 2005:687-693.
    • (2005) Harrison's Principles of Internal Medicine , pp. 687-693
    • Deitcher, S.R.I.1
  • 26
    • 57649147376 scopus 로고    scopus 로고
    • Refludan lepirudin injection, package insert. Wayne, NJ: Bayer HealthCare Pharmaceuticals, Inc, December 2006
    • Refludan (lepirudin injection), package insert. Wayne, NJ: Bayer HealthCare Pharmaceuticals, Inc., December 2006.
  • 27
    • 0345369740 scopus 로고    scopus 로고
    • Recombinant hirudin (lepirudin) provides safe and effective anticoagulation in patients with heparin-induced thrombocytopenia: A prospective study
    • Greinacher A, Volpel H, Janssens U, et al. Recombinant hirudin (lepirudin) provides safe and effective anticoagulation in patients with heparin-induced thrombocytopenia: A prospective study. Circulation 1999;99(1):73-80.
    • (1999) Circulation , vol.99 , Issue.1 , pp. 73-80
    • Greinacher, A.1    Volpel, H.2    Janssens, U.3
  • 28
    • 28444447383 scopus 로고    scopus 로고
    • Lepirudin in patients with heparin-induced thrombocytopenia: Results of the third prospective study (HAT-3) and a combined analysis of HAT-1, HAT-2, and HAT-3
    • Lubenow N, Eichler P, Lietz T, et al. Lepirudin in patients with heparin-induced thrombocytopenia: Results of the third prospective study (HAT-3) and a combined analysis of HAT-1, HAT-2, and HAT-3. J Thromb Haemost 2005;3(11):2428-2436.
    • (2005) J Thromb Haemost , vol.3 , Issue.11 , pp. 2428-2436
    • Lubenow, N.1    Eichler, P.2    Lietz, T.3
  • 29
    • 57649145240 scopus 로고    scopus 로고
    • Argatroban Novastan, package insert. Research Triangle Park, NC: GlaxoSmithKline; July 2005
    • Argatroban (Novastan), package insert. Research Triangle Park, NC: GlaxoSmithKline; July 2005.
  • 30
    • 0025146426 scopus 로고
    • Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors
    • Weitz JI, Hudoba M, Massel D, et al. Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors. J Clin Invest 1990;86(2):385-391.
    • (1990) J Clin Invest , vol.86 , Issue.2 , pp. 385-391
    • Weitz, J.I.1    Hudoba, M.2    Massel, D.3
  • 31
    • 0035836541 scopus 로고    scopus 로고
    • Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia
    • Lewis BE, Wallis DE, Berkowitz SD, et al. Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation 2001;103(14):1838-1843.
    • (2001) Circulation , vol.103 , Issue.14 , pp. 1838-1843
    • Lewis, B.E.1    Wallis, D.E.2    Berkowitz, S.D.3
  • 32
    • 0038285887 scopus 로고    scopus 로고
    • Argatroban anticoagulation in patients with heparin-induced thrombocytopenia
    • Lewis BE, Wallis DE, Leya F, et al. Argatroban anticoagulation in patients with heparin-induced thrombocytopenia. Arch Intern Med 2003;163(15):1849-1856.
    • (2003) Arch Intern Med , vol.163 , Issue.15 , pp. 1849-1856
    • Lewis, B.E.1    Wallis, D.E.2    Leya, F.3
  • 33
    • 57649206095 scopus 로고    scopus 로고
    • Angiomax bivalirudin, package insert. Bedford, OH: BenVenue Laboratories; December 2005
    • Angiomax (bivalirudin), package insert. Bedford, OH: BenVenue Laboratories; December 2005.
  • 34
    • 33645694284 scopus 로고    scopus 로고
    • Evaluation of bivalirudin treatment for heparin induced thrombocytopenia in critically ill patients with hepatic and/or renal dysfunction
    • Kiser TH, Fish DN. Evaluation of bivalirudin treatment for heparin induced thrombocytopenia in critically ill patients with hepatic and/or renal dysfunction. Pharmacotherapy 2006;26(4):452-460.
    • (2006) Pharmacotherapy , vol.26 , Issue.4 , pp. 452-460
    • Kiser, T.H.1    Fish, D.N.2
  • 35
    • 0000503379 scopus 로고    scopus 로고
    • (Orgaran) for the treatment of heparin-induced thrombocytopenia (HIT) and thrombosis: Effects of in vivo thrombin and cross-linked fibrin generations, and evaluation of the clinical significance of in vitro cross-reactivity (XR) of danaparoid for HIT-IgG
    • Warkentin TE. Danaparoid (Orgaran) for the treatment of heparin-induced thrombocytopenia (HIT) and thrombosis: Effects of in vivo thrombin and cross-linked fibrin generations, and evaluation of the clinical significance of in vitro cross-reactivity (XR) of danaparoid for HIT-IgG. Blood 1996;88(Suppl I):626a.
    • (1996) Blood , vol.88 , Issue.SUPPL. I
    • Danaparoid, W.T.E.1
  • 36
    • 57649142122 scopus 로고    scopus 로고
    • Arixtra fondaparinux, package insert. Research Triangle Park, NC: GlaxoSmithKline; April 2008
    • Arixtra (fondaparinux), package insert. Research Triangle Park, NC: GlaxoSmithKline; April 2008.
  • 37
    • 34249804158 scopus 로고    scopus 로고
    • Fondaparinux as a treatment option for heparin-induced thrombocytopenia
    • Papadopoulos S, Flynn JD, Lewis DA. Fondaparinux as a treatment option for heparin-induced thrombocytopenia. Pharmacotherapy 2007;27(6):921-926.
    • (2007) Pharmacotherapy , vol.27 , Issue.6 , pp. 921-926
    • Papadopoulos, S.1    Flynn, J.D.2    Lewis, D.A.3
  • 38
    • 0347949656 scopus 로고    scopus 로고
    • Warfarin-induced skin necrosis and venous limb gangrene in the setting of heparin-induced thrombocytopenia
    • Srinivasan AF, Rice L, Bartholomew JR, et al. Warfarin-induced skin necrosis and venous limb gangrene in the setting of heparin-induced thrombocytopenia. Arch Intern Med 2004;12;164(1):66-70.
    • (2004) Arch Intern Med , vol.164 , Issue.1 , pp. 66-70
    • Srinivasan, A.F.1    Rice, L.2    Bartholomew, J.R.3
  • 39
    • 33747817651 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia
    • Arepally GM, Ortel TL. Heparin-induced thrombocytopenia. N Engl J Med 2006;355(8):809-817.
    • (2006) N Engl J Med , vol.355 , Issue.8 , pp. 809-817
    • Arepally, G.M.1    Ortel, T.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.