Quantitative dynamic contrast enhanced MRI of experimental synovitis in the rabbit knee: Comparison of macromolecular blood pool agents vs. Gadolinium-DOTA

Bio-Medical Materials and Engineering

Volumn 18, Issue 4-5, 2008, Pages 261-272

  Watrin Pinzano, Astrid ^a   Loeuille, Damien ^a   Goebel, Jean Christophe ^a   Lapicque, Françoise ^a   Walter, Fredéric ^b   Robert, Philippe ^c   Netter, Patrick ^a   Corot, Claire ^c   Gillet, Pierre ^a   Blum, Alain ^a,b  

^a UNIVERSITÉ DE LORRAINE   (France)

^b UNIVERSITY HOSPITAL OF NANCY   (France)

^c Laboratoire Guerbet   (France)

Author keywords

Contrast medium; Experimental synovitis; Inflammation; MRI

Indexed keywords

BLOOD; BODY FLUIDS; CONTRAST MEDIA; DIFFUSION; EXPERIMENTS; GADOLINIUM; LAKES; MACROMOLECULES; MEDICAL IMAGING; PATHOLOGY;

BLOOD POOLS; CARRAGEENAN; CONTRAST AGENTS; CONTRAST MEDIUM; EXPERIMENTAL SYNOVITIS; EXTRACELLULAR; INFLAMMATION; INTRAVASCULAR; MR IMAGING; MRI; QUANTITATIVE DYNAMICS; RABBIT KNEES; RESTRICTED DIFFUSIONS; SYNOVIAL FLUIDS; VASCULAR PERMEABILITIES;

AGENTS;

GADOMELITOL; GADOTERATE MEGLUMINE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; P 717; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIFFUSION; DRUG ELIMINATION; DRUG HALF LIFE; HISTOPATHOLOGY; IMAGE ENHANCEMENT; KNEE; KNEE ARTHROGRAPHY; MALE; MEAN RESIDENCE TIME; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLASMA VOLUME; PRIORITY JOURNAL; RABBIT; SYNOVIAL FLUID; SYNOVITIS; SYNOVIUM;

ANIMALS; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; HETEROCYCLIC COMPOUNDS; IMAGE ENHANCEMENT; KNEE JOINT; MAGNETIC RESONANCE IMAGING; MALE; ORGANOMETALLIC COMPOUNDS; RABBITS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SYNOVITIS;

ORYCTOLAGUS CUNICULUS;

EID: 57649186717     PISSN: 09592989     EISSN: None     Source Type: Journal    
DOI: 10.3233/BME-2008-0535     Document Type: Conference Paper

References (33)

1. C. Baudelet, G.O. Cron and B. Gallez, Determination of the maturity and functionality of tumor vasculature by MRI: correlation between BOLD-MRI and DCE-MRI using P792 in experimental fibrosarcoma tumors, Magn. Reson. Med. 56(5) (2006), 1041-1049.
2. A. Blum, D. Loeuille, S. Iochum, R. Kohlmann, B. Grignon and H. Coudane, MR-arthrography: general principles and applications, J. Radiol. 84(6) (2003), 639-657.
3. E. Bogoch, N. Gschwend, B. Bogoch, B. Rahn and S. Perren, Juxtaarticular bone loss in experimental inflammatory arthritis, J. Orthop. Res. 6(5) (1988), 648-656.
4. E. Bogoch, N. Gschwend, B. Bogoch, B. Rahn and S. Perren, Changes in the metaphysis and diaphysis of the femur proximal to the knee in rabbits with experimentally induced inflammatory arthritis, Arthritis Rheum. 32(5) (1989), 617-624.
5. E. Bogoch, N. Gschwend, B. Rahn, E. Moran and S. Perren, Healing of cancellous bone osteotomy in rabbits - Part II: Local reversal of arthritis-induced osteopenia after osteotomy, J. Orthop. Res. 11(2) (1993), 292-298.
6. C. Brochot, B. Bessoud, D. Balvay, C.A. Cuenod, N. Siauve and F.Y. Bois, Evaluation of antiangiogenic treatment effects on tumors' microcirculation by Bayesian physiological pharmacokinetic modeling and magnetic resonance imaging, Magn. Reson. Imaging 24(8) (2006), 1059-1067.
7. C. Corot, X. Violas, P. Robert and M. Port, Pharmacokinetics of three gadolinium chelates with different molecular sizes shortly after intravenous injection in rabbits: relevance to MR angiography, Invest. Radiol. 35(4) (2000), 213-218.
8. J. Dawson, S. Gustard and N. Beckmann, High-resolution three-dimensional magnetic resonance imaging for the investigation of knee joint damage during the time course of antigen-induced arthritis in rabbits, Arthritis Rheum. 42(1) (1999), 119-128.
9. P. Durez, J. Malghem, A.N. Toukap, G. Depresseux, B.R. Lauwerys, R. Westhovens et al., Treatment of early rheumatoid arthritis: A randomized magnetic resonance imaging study comparing the effects of methotrexate alone, methotrexate in combination with infliximab, and methotrexate in combination with intravenous pulse methylprednisolone, Arthritis Rheum. 56(12) (2007), 3919-3927.
10. J.M. Farrant, A.J. Grainger and P.J. O'Connor, Advanced imaging in rheumatoid arthritis. Part 2: erosions, Skeletal Radiol. 36(5) (2007), 381-389.
11. J.M. Farrant, P.J. O'Connor and A.J. Grainger, Advanced imaging in rheumatoid arthritis. Part 1: synovitis, Skeletal Radiol. 36(4) (2007), 269-279.
12. D.L. Gardner, Production of arthritis in the rabbit by the local injection of the mucopolysaccharide caragheenin, Ann. Rheum. Dis. 19 (1960), 369-376.
13. R.J. Hodgson, T. Barnes, S. Connolly, B. Eyes, R.S. Campbell and R. Moots, Changes underlying the dynamic contrast-enhanced MRI response to treatment in rheumatoid arthritis, Skeletal Radiol. 37(3) (2008), 201-207.
14. R.J. Hodgson, S. Connolly, T. Barnes, B. Eyes, R.S. Campbell and R. Moots, Pharmacokinetic modeling of dynamic contrast-enhanced MRI of the hand and wrist in rheumatoid arthritis and the response to anti-tumor necrosis factor-alpha therapy, Magn. Reson. Med. 58(3) (2007), 482-489.
15. R.J. Hodgson, P. O'Connor and R. Moots, MRI of rheumatoid arthritis image quantitation for the assessment of disease activity, progression and response to therapy, Rheumatology (Oxford) 47(1) (2008), 13-21.
16. Q. Kang, Y.H. An and H.F. Butehorn, 3rd and R.J. Friedman, Morphological and mechanical study on the effects of experimentally induced inflammatory knee arthritis in rabbit long bones, J. Mater. Sci. Mater. Med. 9(8) (1998), 463-473.
17. D. Loeuille, I. Chary-Valckenaere, J. Champigneulle, A.C. Rat, F. Toussaint, A. Pinzano-Watrin et al., Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee: correlating magnetic resonance imaging findings with disease severity, Arthritis Rheum. 52(11) (2005), 3492-3501.
18. A.M. Lutz, C. Seemayer, C. Corot, R.E. Gay, K. Goepfert, B.A. Michel et al., Detection of synovial macrophages in an experimental rabbit model of antigen-induced arthritis: ultrasmall superparamagnetic iron oxide-enhanced MR imaging, Radiology 233(1) (2004), 149-157.
19. P. Netter, B. Bannwarth, F. Lapicque, F. Demotes-Mainard, T. Schceverbeke and P. Gillet, Pharmacokinetics and pharmacodynamics of non steroidal anti-inflammatory drugs in synovial fluid, Agents Actions Suppl. 44 (1993), 45-50.
20. M. Ostergaard and M. Klarlund, Importance of timing of post-contrast MRI in rheumatoid arthritis: what happens during the first 60 minutes after IV gadolinium-DTPA?, Ann. Rheum. Dis. 60(11) (2001), 1050-1054.
21. M. Ostergaard, M. Stoltenberg, P. Lovgreen-Nielsen, B. Volck, S. Sonne-Holm and I. Lorenzen, Quantification of synovistis by MRI: correlation between dynamic and static gadolinium-enhanced magnetic resonance imaging and microscopic and macroscopic signs of synovial inflammation, Magn. Reson. Imaging 16(7) (1998), 743-754.
22. C.G. Peterfy, S. Majumdar, P. Lang, C.F. van Dijke, K. Sack and H.K. Genant, MR imaging of the arthritic knee: improved discrimination of cartilage, synovium, and effusion with pulsed saturation transfer and fat-suppressed T1-weighted sequences, Radiology 191(2) (1994), 413-419.
23. M. Port, C. Corot, O. Rousseaux, I. Raynal, L. Devoldere, J.M. Idee et al., P792: a rapid clearance blood pool agent for magnetic resonance imaging: preliminary results, MAGMA 12(2/3) (2001), 121-127.
24. S.T. Proulx, E. Kwok, Z. You, M.O. Papuga, C.A. Beck, D.J. Shealy et al., Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography, Arthritis Rheum. 56(12) (2007), 4024-4037.
25. S.G. Ruehm, H. Christina, X. Violas, C. Corot and J.F. Debatin, MR angiography with a new rapid-clearance blood pool agent: Initial experience in rabbits, Magn. Reson. Med. 48(5) (2002), 844-851.
26. O. Saborowski, G.H. Simon, H.J. Raatschen, M.F. Wendland, Y. Fu, T. Henning et al., MR imaging of antigen-induced arthritis with a new, folate receptor-targeted contrast agent, Contrast Media Mol. Imaging 2(2) (2007), 72-81.
27. P.A. Simkin and J.E. Pizzorno, Transynovial exchange of small molecules in normal human subjects, J. Appl. Physiol. 36(5) (1974), 581-587.
28. G.H. Simon, J. von Vopelius-Feldt, M.F. Wendland, Y. Fu, G. Piontek, J. Schlegel et al., MRI of arthritis: comparison of ultrasmall superparamagnetic iron oxide vs. Gd-DTPA, J. Magn. Reson. Imaging 23(5) (2006), 720-727.
29. J.S. Smolen, D. Aletaha, M. Koeller, M.H. Weisman and P. Emery, New therapies for treatment of rheumatoid arthritis, Lancet 370(9602) (2007), 1861-1874.
30. K. Tamai, M. Yamato, T. Yamaguchi and W. Ohno, Dynamic magnetic resonance imaging for the evaluation of synovitis in patients with rheumatoid arthritis, Arthritis Rheum. 37(8) (1994), 1151-1157.
31. B.E. Van Beers, R. Materne, L. Annet, L. Hermoye, C. Sempoux, F. Peeters et al., Capillarization of the sinusoids in liver fibrosis: noninvasive assessment with contrast-enhanced MRI in the rabbit, Magn. Reson. Med. 49(4) (2003), 692-699.
32. C.F. van Dijke, C.G. Peterfy, R.C. Brasch, P. Lang, T.P. Roberts, D. Shames et al., MR imaging of the arthritic rabbit knee joint using albumin-(Gd-DTPA)30 with correlation to histopathology, Magn. Reson. Imaging 17(2) (1999), 237-245.
33. C.S. Winalski, P. Aliabadi, R.J. Wright, S. Shortkroff, C.B. Sledge and B.N. Weissman, Enhancement of joint fluid with intravenously administered gadopentetate dimeglumine: technique, rationale, and implications, Radiology 187(1) (1993), 179-185.