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Volumn 11, Issue 5, 2008, Pages 597-609

CNS or classic drugs for the treatment of pain in functional dyspepsia? A systematic review and meta-analysis of the literature

Author keywords

Antianxiety; Antidepressants; Antisecretory agents; Brain activity; Epigastric pain; Functional dyspepsia; Prokinetics

Indexed keywords

12 SULFODEHYDROABIETIC ACID; ALEMCINAL; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; CENTRAL NERVOUS SYSTEM AGENTS; CIMETIDINE; CISAPRIDE; FAMOTIDINE; FLUOXETINE; ITOPRIDE; LANSOPRAZOLE; MOSAPRIDE CITRATE; OMEPRAZOLE; PLACEBO; PROKINETIC AGENT; REBAMIPIDE; SIMETHICONE; STOMACH SECRETION INHIBITOR; SULPIRIDE; TANDOSPIRONE;

EID: 57649181420     PISSN: 15333159     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (22)

References (67)
  • 1
    • 0025900575 scopus 로고
    • Non-ulcer dyspepsia: Myths and realities
    • Talley NJ. Non-ulcer dyspepsia: myths and realities. Aliment Pharmacol Ther 1991; 5 Suppl 1:145-162.
    • (1991) Aliment Pharmacol Ther , vol.5 , Issue.SUPPL. 1 , pp. 145-162
    • Talley, N.J.1
  • 2
    • 0025886249 scopus 로고
    • Spectrum of chronic dyspepsia in the presence of the irritable bowel syndrome
    • Talley NJ. Spectrum of chronic dyspepsia in the presence of the irritable bowel syndrome. Scand J Gastroenterol Suppl 1991; 182:7-10.
    • (1991) Scand J Gastroenterol Suppl , vol.182 , pp. 7-10
    • Talley, N.J.1
  • 4
    • 8744272463 scopus 로고    scopus 로고
    • The prevalence and risk factors of functional dyspepsia in a multiethnic population in the United States
    • Shaib Y, El-Serag HB. The prevalence and risk factors of functional dyspepsia in a multiethnic population in the United States. Am J Gastroenterol 2004; 99:2210-2216.
    • (2004) Am J Gastroenterol , vol.99 , pp. 2210-2216
    • Shaib, Y.1    El-Serag, H.B.2
  • 5
    • 0032845018 scopus 로고    scopus 로고
    • Prevalence and impact of upper gastrointestinal symptoms in the Canadian population: Findings from the DIGEST study. Domestic/International Gastroenterology Surveillance Study
    • Tougas G, Chen Y, Hwang P, Liu MM, Eggleston A. Prevalence and impact of upper gastrointestinal symptoms in the Canadian population: Findings from the DIGEST study. Domestic/International Gastroenterology Surveillance Study. Am J Gastroenterol 1999; 94:2845-2854.
    • (1999) Am J Gastroenterol , vol.94 , pp. 2845-2854
    • Tougas, G.1    Chen, Y.2    Hwang, P.3    Liu, M.M.4    Eggleston, A.5
  • 6
    • 0029125418 scopus 로고
    • Irritable bowel syndrome and dyspepsia in the general population: Overlap and lack of stability over time
    • Agreus L, Svardsudd K, Nyren O, Tibblin G. Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability over time. Gastroenterology 1995; 109:671-680.
    • (1995) Gastroenterology , vol.109 , pp. 671-680
    • Agreus, L.1    Svardsudd, K.2    Nyren, O.3    Tibblin, G.4
  • 9
  • 10
    • 0035172993 scopus 로고    scopus 로고
    • Visceral hypersensitivity: Facts, speculations, and challenges
    • Camilleri M, Coulie B, Tack JF. Visceral hypersensitivity: Facts, speculations, and challenges. Gut 2001; 48:125-131.
    • (2001) Gut , vol.48 , pp. 125-131
    • Camilleri, M.1    Coulie, B.2    Tack, J.F.3
  • 11
    • 33845414928 scopus 로고    scopus 로고
    • Is functional dyspepsia of particular concern in women? A review of gender differences in epidemiology, pathophysiologic mechanisms, clinical presentation, and management
    • Flier SN, Rose S. Is functional dyspepsia of particular concern in women? A review of gender differences in epidemiology, pathophysiologic mechanisms, clinical presentation, and management. Am J Gastroenterol 2006; 101:S644-653.
    • (2006) Am J Gastroenterol , vol.101
    • Flier, S.N.1    Rose, S.2
  • 12
    • 23244455376 scopus 로고    scopus 로고
    • Pathophysiology and treatment of functional dyspepsia
    • Tack J, Lee KJ. Pathophysiology and treatment of functional dyspepsia. J Clin Gastroenterol 2005; 39:S211-216.
    • (2005) J Clin Gastroenterol , vol.39
    • Tack, J.1    Lee, K.J.2
  • 13
    • 0018835149 scopus 로고
    • Dyspepsia, antral motor dysfunction, and gastric stasis of solids
    • Rees WD, Miller LJ, Malagelada JR. Dyspepsia, antral motor dysfunction, and gastric stasis of solids. Gastroenterology 1980; 78:360-365.
    • (1980) Gastroenterology , vol.78 , pp. 360-365
    • Rees, W.D.1    Miller, L.J.2    Malagelada, J.R.3
  • 14
    • 0032466914 scopus 로고    scopus 로고
    • Patterns of symptoms in functional dyspepsia: Role of Helicobacter pylori infection and delayed gastric emptying
    • Perri F, Clemente R, Festa V, Annese V, Quitadamo M, Rutgeerts P, Andriulli A. Patterns of symptoms in functional dyspepsia: Role of Helicobacter pylori infection and delayed gastric emptying. Am J Gastroenterol 1998; 93:2082-2088.
    • (1998) Am J Gastroenterol , vol.93 , pp. 2082-2088
    • Perri, F.1    Clemente, R.2    Festa, V.3    Annese, V.4    Quitadamo, M.5    Rutgeerts, P.6    Andriulli, A.7
  • 17
    • 34247636712 scopus 로고    scopus 로고
    • Regional cerebral blood flow during gastric balloon distention in functional dyspepsia
    • Vandenberghe J, Dupont P, Van Oudenhove L, et al. Regional cerebral blood flow during gastric balloon distention in functional dyspepsia. Gastroenterology 2007; 132:1684-1693.
    • (2007) Gastroenterology , vol.132 , pp. 1684-1693
    • Vandenberghe, J.1    Dupont, P.2    Van Oudenhove, L.3
  • 18
    • 0032487919 scopus 로고    scopus 로고
    • Management of nonulcer dyspepsia
    • Fisher RS, Parkman HP. Management of nonulcer dyspepsia. N Engl J Med 1998; 339:1376-1381.
    • (1998) N Engl J Med , vol.339 , pp. 1376-1381
    • Fisher, R.S.1    Parkman, H.P.2
  • 20
    • 0029870009 scopus 로고    scopus 로고
    • A new pharmacologic treatment of functional gastrointestinal disorder. A double-blind placebo-controlled study with mianserin
    • Tanum L, Malt UF. A new pharmacologic treatment of functional gastrointestinal disorder. A double-blind placebo-controlled study with mianserin. Scand J Gastroenterol 1996; 31:318-325.
    • (1996) Scand J Gastroenterol , vol.31 , pp. 318-325
    • Tanum, L.1    Malt, U.F.2
  • 21
    • 0033978273 scopus 로고    scopus 로고
    • Treatment of functional gastrointestinal disorders with antidepressant medications: A meta-analysis
    • Jackson JL, O'Malley PG, Tomkins G, Balden E, Santoro J, Kroenke K. Treatment of functional gastrointestinal disorders with antidepressant medications: a meta-analysis. Am J Med 2000; 108:65-72.
    • (2000) Am J Med , vol.108 , pp. 65-72
    • Jackson, J.L.1    O'Malley, P.G.2    Tomkins, G.3    Balden, E.4    Santoro, J.5    Kroenke, K.6
  • 22
    • 0031744822 scopus 로고    scopus 로고
    • Treating nonulcer dyspepsia considering both functional disorders of the digestive system and psychiatric conditions
    • Mine K, Kanazawa F, Hosoi M, Kinukawa N, Kubo C. Treating nonulcer dyspepsia considering both functional disorders of the digestive system and psychiatric conditions. Dig Dis Sci 1998; 43:1241-1247.
    • (1998) Dig Dis Sci , vol.43 , pp. 1241-1247
    • Mine, K.1    Kanazawa, F.2    Hosoi, M.3    Kinukawa, N.4    Kubo, C.5
  • 24
    • 0034051862 scopus 로고    scopus 로고
    • Comparative effects of levosulpiride and cisapride on gastric emptying and symptoms in patients with functional dyspepsia and gastroparesis
    • Mansi C, Borro P, Giacomini M, Biagini R, Mele MR, Pandolfo N, Savarino V. Comparative effects of levosulpiride and cisapride on gastric emptying and symptoms in patients with functional dyspepsia and gastroparesis. Aliment Pharmacol Ther 2000; 14:561-569.
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 561-569
    • Mansi, C.1    Borro, P.2    Giacomini, M.3    Biagini, R.4    Mele, M.R.5    Pandolfo, N.6    Savarino, V.7
  • 26
    • 20844442156 scopus 로고    scopus 로고
    • Randomised, double-blind, comparative study to evaluate the efficacy and safety of ganaton (itopride hydrochloride) and mosapride citrate in the management of functional dyspepsia
    • Amarapurkar DN, Rane P. Randomised, double-blind, comparative study to evaluate the efficacy and safety of ganaton (itopride hydrochloride) and mosapride citrate in the management of functional dyspepsia. J Indian Med Assoc 2004; 102:735-737, 760.
    • (2004) J Indian Med Assoc , vol.102 , Issue.735-737 , pp. 760
    • Amarapurkar, D.N.1    Rane, P.2
  • 27
    • 0036736387 scopus 로고    scopus 로고
    • A randomized placebo-controlled trial of simethicone and cisapride for the treatment of patients with functional dyspepsia
    • Holtmann G, Gschossmann J, Mayr P, Talley NJ. A randomized placebo-controlled trial of simethicone and cisapride for the treatment of patients with functional dyspepsia. Aliment Pharmacol Ther 2002; 16:1641-1648.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 1641-1648
    • Holtmann, G.1    Gschossmann, J.2    Mayr, P.3    Talley, N.J.4
  • 28
    • 20544442066 scopus 로고    scopus 로고
    • A prospective study of oesophageal 24-h ambulatory pH monitoring in patients with functional dyspepsia
    • Gerson LB, Triadafilopoulos G. A prospective study of oesophageal 24-h ambulatory pH monitoring in patients with functional dyspepsia. Dig Liver Dis 2005; 37:87-91.
    • (2005) Dig Liver Dis , vol.37 , pp. 87-91
    • Gerson, L.B.1    Triadafilopoulos, G.2
  • 30
    • 20444375508 scopus 로고    scopus 로고
    • Usefulness of famotidine in functional dyspepsia patient treatment: Comparison among prokinetic, acid suppression and antianxiety therapies
    • Seno H, Nakase H, Chiba T. Usefulness of famotidine in functional dyspepsia patient treatment: Comparison among prokinetic, acid suppression and antianxiety therapies. Aliment Pharmacol Ther 2005; 21 Suppl 2:32-36.
    • (2005) Aliment Pharmacol Ther , vol.21 , Issue.SUPPL. 2 , pp. 32-36
    • Seno, H.1    Nakase, H.2    Chiba, T.3
  • 31
    • 0030922816 scopus 로고    scopus 로고
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315:629-634.
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315:629-634.
  • 32
    • 0031987329 scopus 로고    scopus 로고
    • Effect of amitriptyline on symptoms, sleep, and visceral perception in patients with functional dyspepsia
    • Mertz H, Fass R, Kodner A, Yan-Go F, Fullerton S, Mayer EA. Effect of amitriptyline on symptoms, sleep, and visceral perception in patients with functional dyspepsia. Am J Gastroenterol 1998; 93:160-165.
    • (1998) Am J Gastroenterol , vol.93 , pp. 160-165
    • Mertz, H.1    Fass, R.2    Kodner, A.3    Yan-Go, F.4    Fullerton, S.5    Mayer, E.A.6
  • 33
    • 0031988876 scopus 로고    scopus 로고
    • Effects of levosulpiride in patients with functional dyspepsia accompanied by delayed gastric emptying
    • Song CW, Chun HJ, Kim CD, Ryu HS, Choe JG, Hyun JH. Effects of levosulpiride in patients with functional dyspepsia accompanied by delayed gastric emptying. Korean J Intern Med 1998; 13:15-21.
    • (1998) Korean J Intern Med , vol.13 , pp. 15-21
    • Song, C.W.1    Chun, H.J.2    Kim, C.D.3    Ryu, H.S.4    Choe, J.G.5    Hyun, J.H.6
  • 34
    • 0037263305 scopus 로고    scopus 로고
    • Effect of fluoxetine on symptoms and gastric dysrhythmia in patients with functional dyspepsia
    • Wu CY, Chou LT, Chen HP, Chang CS, Wong PG, Chen GH. Effect of fluoxetine on symptoms and gastric dysrhythmia in patients with functional dyspepsia. Hepatogastroenterology 2003; 50:278-283.
    • (2003) Hepatogastroenterology , vol.50 , pp. 278-283
    • Wu, C.Y.1    Chou, L.T.2    Chen, H.P.3    Chang, C.S.4    Wong, P.G.5    Chen, G.H.6
  • 35
    • 0036188737 scopus 로고    scopus 로고
    • Effect of acute and chronic levosulpiride administration on gastric tone and perception in functional dyspepsia
    • Distrutti E, Fiorucci S, Hauer SK, Pensi MO, Vanasia M, Morelli A. Effect of acute and chronic levosulpiride administration on gastric tone and perception in functional dyspepsia. Aliment Pharmacol Ther 2002; 16:613-622.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 613-622
    • Distrutti, E.1    Fiorucci, S.2    Hauer, S.K.3    Pensi, M.O.4    Vanasia, M.5    Morelli, A.6
  • 38
    • 21044441006 scopus 로고    scopus 로고
    • Dyspeptic patients with visceral hypersensitivity: Sensitisation of pain specific or multimodal pathways?
    • Vandenberghe J, Vos R, Persoons P, Demyttenaere K, Janssens J, Tack J. Dyspeptic patients with visceral hypersensitivity: Sensitisation of pain specific or multimodal pathways? Gut 2005; 54:914-919.
    • (2005) Gut , vol.54 , pp. 914-919
    • Vandenberghe, J.1    Vos, R.2    Persoons, P.3    Demyttenaere, K.4    Janssens, J.5    Tack, J.6
  • 39
    • 35348889820 scopus 로고    scopus 로고
    • Functional dyspepsia: Mechanisms of symptom generation and appropriate management of patients
    • Camilleri M. Functional dyspepsia: Mechanisms of symptom generation and appropriate management of patients. Gastroenterol Clin North Am 2007; 36:649-664.
    • (2007) Gastroenterol Clin North Am , vol.36 , pp. 649-664
    • Camilleri, M.1
  • 41
    • 33748306032 scopus 로고    scopus 로고
    • Review article: Modulation of the brain-gut axis as a therapeutic approach in gastrointestinal disease
    • Mayer EA, Tillisch K, Bradesi S. Review article: Modulation of the brain-gut axis as a therapeutic approach in gastrointestinal disease. Aliment Pharmacol Ther 2006; 24:919-933.
    • (2006) Aliment Pharmacol Ther , vol.24 , pp. 919-933
    • Mayer, E.A.1    Tillisch, K.2    Bradesi, S.3
  • 42
    • 0036084196 scopus 로고    scopus 로고
    • Evolving concepts in the pathophysiology of functional gastrointestinal disorder
    • Hunt RH. Evolving concepts in the pathophysiology of functional gastrointestinal disorder. J Clin Gastroenterol 2002; 35:S2-6.
    • (2002) J Clin Gastroenterol , vol.35
    • Hunt, R.H.1
  • 44
    • 34447133497 scopus 로고    scopus 로고
    • Mechanisms of serotonergic agents for treatment of gastrointestinal motility and functional bowel disorders
    • Kindt S, Tack J. Mechanisms of serotonergic agents for treatment of gastrointestinal motility and functional bowel disorders. Neurogastroenterol Motil 2007; 19 Suppl 2:32-39.
    • (2007) Neurogastroenterol Motil , vol.19 , Issue.SUPPL. 2 , pp. 32-39
    • Kindt, S.1    Tack, J.2
  • 45
    • 37549025463 scopus 로고    scopus 로고
    • Gastric fundic distension activates fronto-limbic structures but not primary somatosensory cortex: A functional magnetic resonance imaging study
    • Ladabaum U, Roberts TP, McGonigle DJ. Gastric fundic distension activates fronto-limbic structures but not primary somatosensory cortex: a functional magnetic resonance imaging study. Neuroimage 2007; 34:724-732.
    • (2007) Neuroimage , vol.34 , pp. 724-732
    • Ladabaum, U.1    Roberts, T.P.2    McGonigle, D.J.3
  • 47
    • 0030471692 scopus 로고    scopus 로고
    • Quality of life in functional dyspepsia
    • Talley NJ. Quality of life in functional dyspepsia. Scand J Gastroenterol Suppl 1996; 221:21-22.
    • (1996) Scand J Gastroenterol Suppl , vol.221 , pp. 21-22
    • Talley, N.J.1
  • 48
    • 0031730388 scopus 로고    scopus 로고
    • Are psychosocial factors of aetiological importance in functional dyspepsia?
    • Olden KW. Are psychosocial factors of aetiological importance in functional dyspepsia? Baillieres Clin Gastroenterol 1998; 12:557-571.
    • (1998) Baillieres Clin Gastroenterol , vol.12 , pp. 557-571
    • Olden, K.W.1
  • 49
    • 1442350424 scopus 로고    scopus 로고
    • Psychosocial factors and the disorders of GI function: What is the link?
    • Drossman DA. Psychosocial factors and the disorders of GI function: What is the link? Am J Gastroenterol 2004; 99:358-360.
    • (2004) Am J Gastroenterol , vol.99 , pp. 358-360
    • Drossman, D.A.1
  • 51
    • 0024520544 scopus 로고
    • Drug treatment of functional dyspepsia. A meta-analysis of randomized controlled clinical trials
    • Dobrilla G, Comberlato M, Steele A, Vallaperta P. Drug treatment of functional dyspepsia. A meta-analysis of randomized controlled clinical trials. J Clin Gastroenterol 1989; 11:169-177.
    • (1989) J Clin Gastroenterol , vol.11 , pp. 169-177
    • Dobrilla, G.1    Comberlato, M.2    Steele, A.3    Vallaperta, P.4
  • 53
    • 0034916957 scopus 로고    scopus 로고
    • Treatment of non-ulcer dyspepsia: A meta-analysis of placebo-controlled prospective studies
    • Allescher HD, Bockenhoff A, Knapp G, Wienbeck M, Hartung J. Treatment of non-ulcer dyspepsia: A meta-analysis of placebo-controlled prospective studies. Scand J Gastroenterol 2001; 36:934-941.
    • (2001) Scand J Gastroenterol , vol.36 , pp. 934-941
    • Allescher, H.D.1    Bockenhoff, A.2    Knapp, G.3    Wienbeck, M.4    Hartung, J.5
  • 55
    • 1842586719 scopus 로고    scopus 로고
    • Systematic review: The methodological quality of trials affects estimates of treatment efficacy in functional (non-ulcer) dyspepsia
    • Abraham NS, Moayyedi P, Daniels B, Veldhuyzen Van Zanten SJ. Systematic review: The methodological quality of trials affects estimates of treatment efficacy in functional (non-ulcer) dyspepsia. Aliment Pharmacol Ther 2004; 19:631-641.
    • (2004) Aliment Pharmacol Ther , vol.19 , pp. 631-641
    • Abraham, N.S.1    Moayyedi, P.2    Daniels, B.3    Veldhuyzen Van Zanten, S.J.4
  • 57
    • 7644242215 scopus 로고    scopus 로고
    • The efficacy of proton pump inhibitors in nonulcer dyspepsia: A systematic review and economic analysis
    • Moayyedi P, Delaney BC, Vakil N, Forman D, Talley NJ. The efficacy of proton pump inhibitors in nonulcer dyspepsia: A systematic review and economic analysis. Gastroenterology 2004; 127:1329-1337.
    • (2004) Gastroenterology , vol.127 , pp. 1329-1337
    • Moayyedi, P.1    Delaney, B.C.2    Vakil, N.3    Forman, D.4    Talley, N.J.5
  • 58
    • 33947586728 scopus 로고    scopus 로고
    • Proton pump inhibitors: Effective first-line treatment for management of dyspepsia
    • Peura DA, Gudmundson J, Siepman N, Pilmer BL, Freston J. Proton pump inhibitors: Effective first-line treatment for management of dyspepsia. Dig Dis Sci 2007; 52:983-987.
    • (2007) Dig Dis Sci , vol.52 , pp. 983-987
    • Peura, D.A.1    Gudmundson, J.2    Siepman, N.3    Pilmer, B.L.4    Freston, J.5
  • 60
    • 0033799936 scopus 로고    scopus 로고
    • Short course acid suppressive treatment for patients with functional dyspepsia: Results depend on Helicobacter pylori status. The Frosch Study Group
    • Blum AL, Arnold R, Stolte M, Fischer M, Koelz HR. Short course acid suppressive treatment for patients with functional dyspepsia: Results depend on Helicobacter pylori status. The Frosch Study Group. Gut 2000; 47:473-480.
    • (2000) Gut , vol.47 , pp. 473-480
    • Blum, A.L.1    Arnold, R.2    Stolte, M.3    Fischer, M.4    Koelz, H.R.5
  • 63
    • 0031038729 scopus 로고    scopus 로고
    • Effect of cisapride on functional dyspepsia in patients with and without histological gastritis: A double-blind placebo-controlled trial
    • Yeoh KG, Kang JY, Tay HH, Gwee KA, Tan CC, Teh M, Choo HF, Chintana-Wilde W. Effect of cisapride on functional dyspepsia in patients with and without histological gastritis: A double-blind placebo-controlled trial. J Gastroenterol Hepatol 1997; 12:13-18.
    • (1997) J Gastroenterol Hepatol , vol.12 , pp. 13-18
    • Yeoh, K.G.1    Kang, J.Y.2    Tay, H.H.3    Gwee, K.A.4    Tan, C.C.5    Teh, M.6    Choo, H.F.7    Chintana-Wilde, W.8
  • 65
    • 33750433592 scopus 로고    scopus 로고
    • Effect of a gastro-protective agent, rebamipide, on symptom improvement in patients with functional dyspepsia: A double-blind placebo-controlled study in Japan
    • Miwa H, Osada T, Nagahara A, Ohkusa T, Hojo M, Tomita T, Hori K, Matsumoto T, Sato N. Effect of a gastro-protective agent, rebamipide, on symptom improvement in patients with functional dyspepsia: a double-blind placebo-controlled study in Japan. J Gastroenterol Hepatol 2006; 21:1826-1831.
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 1826-1831
    • Miwa, H.1    Osada, T.2    Nagahara, A.3    Ohkusa, T.4    Hojo, M.5    Tomita, T.6    Hori, K.7    Matsumoto, T.8    Sato, N.9


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