Gene expression of adrenoceptors in the hearts of cold-acclimated rats exposed to a novel stressor

Annals of the New York Academy of Sciences

Volumn 1148, Issue , 2008, Pages 393-399

  Tillinger, Andrej ^a,d   Mysliveček, Jaromír ^b   Nováková, Martina ^b   Krizanova, Olga ^c   Kvetňanský, Richard ^a  

^a INSTITUTE OF EXPERIMENTAL ENDOCRINOLOGY   (Slovakia)

^b CHARLES UNIVERSITY   (Czech Republic)

^c INSTITUTE OF MOLECULAR PHYSIOLOGY AND GENETICS   (Slovakia)

^d INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Adrenoceptors; Cold; Gene expression; Heart; Immobilization

Indexed keywords

ALPHA 1B ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CHRONIC STRESS; COLD ACCLIMATIZATION; COLD STRESS; CONFERENCE PAPER; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HEART CONTRACTION; HEART FUNCTION; HEART LEFT ATRIUM; HEART LEFT VENTRICLE; HEART MUSCLE CONTRACTILE FORCE; HEART PROTECTION; HEART RATE; IMMOBILIZATION STRESS; LONG TERM EXPOSURE; MALE; NONHUMAN; RAT; RECEPTOR GENE;

ANIMALIA; RATTUS;

EID: 57649155881     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1410.024     Document Type: Conference Paper

References (25)

1. Brodde, O.E. & M.C. Michel. 1999. Adrenergic and muscarinic receptors in the human heart. Pharmacol. Rev. 51 : 651 690.
2. Brodde, O.E. & K. Leineweber. 2004. Autonomic receptor systems in the failing and aging human heart: similarities and differences. Eur. J. Pharmacol. 500 : 167 176.
3. Xiao, R.P. et al. 2006. Subtype-specific α1- and β-adrenoceptor signaling in the heart. Trends Pharmacol. Sci. 27 : 330 337.
4. Gauthier, C., D. Langin & J.L. Ballig. 2000. Beta3-adrenoceptors in the cardiovascular system. Trends Pharmacol. Sci. 21 : 426 431.
5. Rozec, B. & C. Gauthier. 2006. β3-Adrenoceptors in the cardiovascular system: Putative roles in human pathologies. Pharmacol. Therap. 111 : 652 673.
6. Li, K. et al. 1997. Myocardial α1-adrenoceptor: inotropic effect and physiologic and pathologic implications. Life Sci. 60 : 1305 1318.
7. Zhang, Y.Y. et al. 1999. α1-adrenoceptor subtypes mediating inotropic responses in rat heart. J. Pharmacol. Exp. Ther. 291 : 829 836.
8. Selye, H. 1936. A syndrome produced by diverse nocuous agents. Nature 138 : 32.
9. Pacak, K. & M. Palkovits. 2001. Stressor specificity of central neuroendocrine responses: implications for stress-related disorders. Endocr. Rev. 22 : 502 548.
10. Kvetnansky, R. & L. Mikulaj. 1970. Adrenal and urinary catecholamines in rats during adaptation to repeated immobilization stress. Endocrinology 87 : 738 743.
11. Myslivecek, J. et al. 2006. Distribution of mRNA and binding sites of adrenoceptors and muscarinic receptors in the rat heart. Life Sci. 79 : 112 120.
12. Esler, M. et al. 1997. Adrenergic nervous system in heart failure. Am. J. Cardiol. 80 : 7 14.
13. Kvetnansky, R. et al. 2002. Novel stressors exaggerate tyrosine hydroxylase gene expression in the adrenal medulla of rats exposed to long-term cold stress. In Stress. Neuronal, Endocrine and Molecular Studies. R. McCarty, G. Aguilera, E.L. Sabban & R. Kvetnansky, Eds 121 128. Taylor & Francis. New York, NY.
14. Dronjak, S. et al. 2002. Effects of novel stressors on plasma catecholamine levels in rats exposed to long-term cold. In Stress. Neuronal, Endocrine and Molecular Studies. R. McCarty, G. Aguilera, E.L. Sabban & R. Kvetnansky, Eds. : 83 89. Taylor & Francis. New York, NY.
15. Liang, W. et al. 2003. Resistance of the human beta1-adrenergic receptor to agonist-mediated down-regulation. Role of the C terminus in determining beta-subtype degradation. J. Biol. Chem. 278 : 39773 39781.
16. Myslivecek, J. et al. 2004. The effects of short-term immobilization stress on muscarinic receptors, beta-adrenoceptors, and adenylyl cyclase in different heart regions. Ann. N. Y. Acad. Sci. 1018 : 315 322.
17. Skeberdis, V.A. 2004. Structure and function of beta3-adrenergic receptors. Medicina (Kaunas) 40 : 407 413.
18. Morimoto, A. et al. 2004. Endogenous beta3-adrenoreceptor activation contributes to left ventricular and cardiomyocyte dysfunction in heart failure. Am. J. Physiol. Heart Circ. Physiol. 286 : H2425 H2433.
19. Zhang, Z.S. et al. 2005. Enhanced inhibition of L-type Ca2+ current by {beta}3-adrenergic stimulation in failing rat heart. J. Pharmacol. Exp. Ther. 315 : 1203 1211.
20. Barbier, J. et al. 2004. Effect of training on beta1 beta2 beta3 adrenergic and M2 muscarinic receptors in rat heart. Med. Sci. Sports Exerc. 36 : 949 954.
21. U'Prichard, D.C. & R. Kvetnansky. 1980. Central and peripheral adrenergic receptors in acute and repeated immobilization stress. In Catecholamines and Stress: Recent Advances. E. Usdin, R. Kvetnansky & I.J. Kopin, Eds. : 299 308. Elsevier. New York, NY.
22. Kvetnansky, R. & T. Torda. 1983. Changes of heart catecholamine levels, metabolism and adrenergic receptors in acutely and repeatedly stressed rats. In Cardiac Adaptation to Hemodynamic Overload Training and Stress. R. Jacob, E. Darmstadt & D. Steinkopf, Eds. : 265 266. Dr. Dietrich Steinkopff Verlag. Darmstadt, Germany.
23. Steinfath, M. et al. 1992. Cardiac α1-adrenoceptor densities in different mammalian species. Br. J. Pharmacol. 107 : 185 188.
24. Price, D.T. et al. 1994. Expression of α1-adrenergic receptor subtype mRNA in rat tissues and human SK-N-MC neuronal cells: Implications for α1-adrenergic subtype classification. Mol. Pharmacol. 46 : 221 226.
25. Wolff, D.W. et al. 1998. Distribution of α1-adrenergic receptor mRNA species in rat heart. J. Cardiovasc. Pharmacol. 32 : 117 122.