Barbiturate infusion for intractable intracranial hypertension and its effect on brain oxygenation

Neurosurgery

Volumn 63, Issue 5, 2008, Pages 880-886

  Chen, H Isaac ^a   Malhotra, Neil R ^a,b   Oddo, Mauro ^a   Heuer, Gregory G ^a   Levine, Joshua M ^a   Leroux, Peter D ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Barbiturates; Brain tissue oxygen; Cerebral oxygenation; Intracranial hypertension

Indexed keywords

FENTANYL; MANNITOL; MIDAZOLAM; NIMODIPINE; PENTOBARBITAL; PROPOFOL; SODIUM CHLORIDE; VECURONIUM;

ADULT; AGED; ANALGESIA; ARTERIAL OXYGEN SATURATION; ARTICLE; ARTIFICIAL VENTILATION; BODY TEMPERATURE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN OXYGEN CONSUMPTION; BRAIN OXYGEN TENSION; BRAIN PERFUSION; BRAIN TEMPERATURE; BRAIN TISSUE; BRAIN TUMOR; CLINICAL ARTICLE; COMA; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG DOSE TITRATION; DRUG INFUSION; EMERGENCY HEALTH SERVICE; ENDOVASCULAR SURGERY; FEMALE; HEART RATE; HUMAN; INTENSIVE CARE UNIT; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; INTRACRANIAL PRESSURE MONITORING; LOADING DRUG DOSE; LOGISTIC REGRESSION ANALYSIS; MALE; MEAN ARTERIAL PRESSURE; NEUROSURGERY; OXYGEN SATURATION; PRIORITY JOURNAL; RESUSCITATION; SEDATION; SUBARACHNOID HEMORRHAGE; TRAUMATIC BRAIN INJURY;

ADULT; AGED; BARBITURATES; BRAIN; BRAIN INJURIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; INTENSIVE CARE; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; MALE; MIDDLE AGED; MONITORING, PHYSIOLOGIC; OXYGEN; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 57649138105     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000327882.10629.06     Document Type: Article

References (35)

1. Allen CH, Ward JD: An evidence-based approach to management of increased intracranial pressure. Crit Care Clin 14:485-495, 1998.
2. Anonymous: The Brain Trauma Foundation. The American Association of Neurological Surgeons. The Joint Section on Neurotrauma and Critical Care. Use of barbiturates in the control of intracranial hypertension. J Neurotrauma 17:527-530, 2000.
3. 2 reactivity and barbiturate reactivity in patients with severe head injury. Acta Neurochir (Wien) 98:153-163, 1989.
4. Cormio M, Gopinath SP, Valadka A, Robertson CS: Cerebral hemodynamic effects of pentobarbital coma in head-injured patients. J Neurotrauma 16:927-936, 1999,
5. Cruz J: Adverse effects of pentobarbital on cerebral venous oxygenation of comatose patients with acute traumatic brain swelling: Relationship to outcome. J Neurosurg 85:758-761, 1996.
6. Ehrnebo M: Pharmacokinetics and distribution properties of pentobarbital in humans following oral and intravenous administration. J Pharm Sci 63:1114-1118, 1974.
7. 2, ICP, and CPP in severe brain injury. Neurosurg Rev 23:94-97, 2000.
8. Goodman JC, Valadka AB, Gopinath SP, Cormio M, Robertson CS: Lactate and excitatory amino acids measured by microdialysis are decreased by pentobarbital coma in head-injured patients. J Neurotrauma 13:549-556, 1996.
9. Gopinath SP, Robertson CS, Contant CF, Hayes C, Feldman Z, Narayan RK, Grossman RG: Jugular venous desaturation and outcome after head injury. J Neurol Neurosurg Psychiatry 57:717-723, 1994.
10. Harbaugh RD, James HE, Marshall LF, Shapiro HM, Laurin R: Acute therapeutic modalities for experimental vasogenic edema. Neurosurgery 5:656-665, 1979.
11. Hoff JT, Marshall L: Barbiturates in neurosurgery. Clin Neurosurg 26:637-642, 1979.
12. Imberti R, Bellinzona G, Riccardi F, Pagani M, Langer M: Cerebral perfusion pressure and cerebral tissue oxygen tension in a patient during cardiopulmonary resuscitation. Intensive Care Med 29:1016-1019, 2003.
13. Le Roux PD, Newell DW, Lam AM, Grady MS, Winn HR: Cerebral arteriovenous oxygen difference: A predictor of cerebral infarction and outcome in patients with severe head injury. J Neurosurg 87:1-8, 1997.
14. Marshall LF, Smith RW, Shapiro HM: The outcome with aggressive treatment in severe head injuries. Part I: The significance of intracranial pressure monitoring. J Neurosurg 50:20-25, 1979.
15. Marshall LF, Smith RW, Shapiro HM: The outcome with aggressive treatment in severe head injuries. Part II: Acute and chronic barbiturate administration in the management of head injury. J Neurosurg 50:26-30, 1979.
16. McKhann GM, Mayer S, Le Roux PD: Perioperative and ICU care of patients with aneurysmal subarachnoid hemorrhage, in Le Roux PD, Newell DW, Winn HR (eds): Management of Cerebral Aneurysms. Philadelphia, Elsevier Science, 2004, pp 431-454.
17. Menon DK, Coles JP, Gupta AK, Fryer TD, Smielewski P, Chatfield DA, Aigbirhio F, Skepper JN, Minhas PS, Hutchinson PJ, Carpenter TA, Clark JC, Pickard JD: Diffusion limited oxygen delivery following head injury. Crit Care Med 32:1384-1390, 2004.
18. Narayan RK, Kishore PR, Becker DP, Ward JD, Enas GG, Greenberg RP, Domingues Da Silva A, Lipper MH, Choi SC, Mayhall CG, Lutz HA 3rd, Young HF: Intracranial pressure: To monitor or not to monitor? A review of our experience with severe head injury. J Neurosurg 56:650-659, 1982.
19. Nordström CH: Assessment of critical thresholds for cerebral perfusion pressure by performing bedside monitoring of cerebral energy metabolism. Neurosurg Focus 15:E5, 2003.
20. Nordström CH, Messeter K, Sundbärg G, Schalén W, Werner M, Ryding E: Cerebral blood flow, vasoreactivity, and oxygen consumption during barbiturate therapy in severe traumatic brain lesions. J Neurosurg 68:424-431, 1988.
21. Pérez-Bárcena J, Barceló B, Homar J, Abadal JM, Molina FJ, de la Peña A, Sahuquillo J, Ibáñez J: Comparison of the effectiveness of pentobarbital and thiopental in patients with refractory intracranial hypertension. Preliminary report of 20 patients [in Spanish]. Neurocirugia (Astur) 16:5-13, 2005.
22. Rea GL, Rockswold GL: Barbiturate therapy in uncontrolled intracranial hypertension. Neurosurgery 12:401-404, 1983.
23. Robertson C: Critical care management of traumatic brain injury, in Winn HR (ed): Youmans Neurological Surgery. Philadelphia, Saunders, 2004, pp 5103-5144.
24. Rockoff MA, Marshall LF, Shapiro HM: High-dose barbiturate therapy in humans: A clinical review of 60 patients. Ann Neurol 6:194-199, 1979.
25. Rutigliano D, Egnor MR, Priebe CJ, McCormack JE, Strong N, Scriven RJ, Lee TK: Decompressive craniectomy in pediatric patients with traumatic brain injury with intractable elevated intracranial pressure. J Pediatr Surg 41:83-87, 2006.
26. Schwartz ML, Tator CH, Rowed DW, Reid SR, Meguro K, Andrews DF: The University of Toronto head injury treatment study: A prospective, randomized comparison of pentobarbital and mannitol. Can J Neurol Sci 11:434-440, 1984.
27. Selman WR, Spetzler RF, Roski RA, Roessmann U, Crumrine R, Macko R: Barbiturate coma in focal cerebral ischemia. Relationship of protection to timing of therapy. J Neurosurg 56:685-6690, 1982.
28. Shapiro HM, Wyte SR, Loeser J: Barbiturate-augmented hypothermia for reduction of persistent intracranial hypertension. J Neurosurg 40:90-100, 1974.
29. Stiefel MF, Heuer CC, Abrahams JM, Bloom S, Smith MJ, Maloney-Wilensky E, Grady MS, LeRoux PD: The effect of nimodipine on cerebral oxygenation in patients with poor-grade subarachnoid hemorrhage. J Neurosurg 101:594-599, 2004.
30. Stiefel MF, Heuer CC, Smith MJ, Bloom S, Maloney-Wilensky E, Gracias VH, Grady MS, LeRoux PD: Cerebral oxygenation following decompressive hemicraniectomy for the treatment of refractory intracranial hypertension. J Neurosurg 101:241-247, 2004.
31. Stiefel MF, Spiotta A, Gracias VH, Garuffe AM, Guillamondegui O, Maloney-Wilensky E, Bloom S, Grady MS, LeRoux PD: Reduced mortality rate in patients with severe traumatic brain injury treated with brain tissue oxygen monitoring. J Neurosurg 103:805-811, 2005.
32. van den Brink WA, van Santbrink H, Steyerberg EW, Avezaat CJ, Suazo JA, Hogesteeger C, Jansen WJ, Kloos LM, Vermeulen J, Maas AI: Brain oxygen tension in severe head injury. Neurosurgery 46:868-878, 2000.
33. van Santbrink H, vd Brink WA, Steyerberg EW, Carmona Suazo JA, Avezaat CJ, Maas AI: Brain tissue oxygen response in severe traumatic brain injury. Acta Neurochir (Wien) 145:429-438, 2003.
34. Ward JD, Becker DP, Miller JD, Choi SC, Marmarou A, Wood C, Newlon PG, Keenan R: Failure of prophylactic barbiturate coma in the treatment of severe head injury. J Neurosurg 62:383-388, 1985.
35. Wilensky EM, Bloom S, Leichter D, Verdiramo AM, Ledwith M, Stiefel M, LeRoux P, Grady MS: Brain tissue oxygen practice guidelines using the LICOX CMP monitoring system. J Neurosci Nurs 37:278-288, 2005.