Adverse effects of pentobarbital on cerebral venous oxygenation of comatose patients with acute traumatic brain swelling: Relationship to outcome

Journal of Neurosurgery

Volumn 85, Issue 5, 1996, Pages 758-761

  Cruz, Julio ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

barbiturate therapy; coma; head injury; intracranial pressure; jugular oxyhemoglobin saturation; outcome

Indexed keywords

PENTOBARBITAL;

ADULT; AGED; ARTICLE; BRAIN EDEMA; BRAIN HYPOXIA; BRAIN INJURY; BRAIN OXYGEN CONSUMPTION; CLINICAL TRIAL; COMA; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; HUMAN; INJURY SCALE; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MEAN ARTERIAL PRESSURE; OXYGEN SATURATION; PRIORITY JOURNAL;

EID: 0029828290     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1996.85.5.0758     Document Type: Article

References (16)

1. Cruz J: An additional therapeutic effect of adequate hyperventilation in severe acute brain trauma: normalization of cerebral glucose uptake. J Neurosurg 82:379-385, 1995
2. Cruz J: Combined continuous monitoring of systemic and cerebral oxygenation in acute brain injury: preliminary observations. Crit Care Med 21:1225-1232, 1993
3. Cruz J: On-line monitoring of global cerebral hypoxia in acute brain injury. Relationship to intracranial hypertension. J Neurosurg 79:228-233, 1993
4. Cruz J, Jaggi JL, Hoffstad OJ: Cerebral blood flow and oxygen consumption in acute brain injury with acute anemia: an alternative for the cerebral metabolic rate of oxygen consumption? Crit Care Med 21:1218-1224, 1993
5. Cruz J, Jaggi JL, Hoffstad OJ: Cerebral blood flow, vascular resistance, and oxygen metabolism in acute brain trauma: redefining the role of cerebral perfusion pressure? Crit Care Med 23:1412-1417, 1995
6. Cruz J, Miner ME, Allen SJ, et al: Continuous monitoring of cerebral oxygenation in acute brain injury: injection of mannitol during hyperventilation. J Neurosurg 73:725-730, 1990
7. Eisenberg HM, Frankowski RF, Contant CF, et al: High-dose barbiturate control of elevated intracranial pressure in patients with severe head injury. J Neurosurg 69:15-23, 1988
8. Gennarelli TA, Spielman GM, Langfitt TW, et al: Influence of the type of intracranial lesion on outcome from severe head injury. A multicenter study using a new classification system. J Neurosurg 56:26-32, 1982
9. Jennett B, Bond M: Assessment of outcome after severe brain damage. A practical scale. Lancet 1:480-484, 1975
10. Marion DW, Obrist WD, Carlier PM, et al: The use of moderate therapeutic hypothermia for patients with severe head injuries: a preliminary report. J Neurosurg 79:354-362, 1993
11. Marshall LF, Smith RW, Shapiro HM: The outcome with aggressive treatment in severe head injuries. Part II: Acute and chronic barbiturate administration in the management of head injury. J Neurosurg 50:26-30, 1979
12. Muizelaar JP, Marmarou A, Ward JD, et al: Adverse effects of prolonged hyperventilation in patients with severe head injury: a randomized clinical trial. J Neurosurg 75:731-739, 1991
13. Muizelaar JP, Marmarou A, Young HF, et al: Improving the outcome of severe head injury with the oxygen radical scavenger polyethylene glycol-conjugated superoxide dismutase: a Phase II trial. J Neurosurg 78:375-382, 1993
14. Nordström CH, Messeter K, Sundbärg G, et al: Cerebral blood flow, vasoreactivity, and oxygen consumption during barbiturate therapy in severe traumatic brain lesions. J Neurosurg 68: 424-431, 1988
15. Rosner MJ, Rosner SD, Johnson AH: Cerebral perfusion pressure: management protocol and clinical results. J Neurosurg 83:949-962, 1995
16. Teasdale G, Jennett B: Assessment of coma and impaired consciousness. A practical scale. Lancet 2:81-84, 1974