The fragmentation pathway of the nucleosides under the electrospray ionization multi-stage mass spectrometry

Life Science Journal

Volumn 5, Issue 2, 2008, Pages 37-40

  Liu, Ruoyu ^a,c   Ye, Yong ^a,b   Qiang, Liming ^a   Liao, Xincheng ^a   Zhao, Yufen ^a,b  

^a ZHENGZHOU UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

^c NANYANG NORMAL UNIVERSITY   (China)

Author keywords

ESI MSn; Fragmentation pathway; Nucleosides; Retro Diels Alder; Ring contraction

Indexed keywords

ALNUS;

EID: 57549101875     PISSN: 10978135     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Ueno T, Shirasaka T, Mitsuya H. Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2′,3′-dideoxynucleoside 5′-triphosphates. The Journal of Biological Chemistry 1995; 270(40): 23605 - 11.
2. Cyrille B, Valerie ED, Naheed M, et al. Design, synthesis and evaluation of peptide libraries as potential anti-HIV compounds via inhibition of gp120/cell membrane interactions using the gp120/CD4/ Fab17 crystal structure. European Journal of Medicinal Chemistry 2002; 37(11): 883 - 90.
3. Patrick V, Thierry C, Christophe P, et al. Synthesis of new covalently bound-carrageenan-AZT conjugates with improved anti-HIV activities. Journal of Medicinal Chemistry 2002; 45(6): 1275 - 83.
4. Wong A, Toth I. Lipid, sugar and liposaccharide based delivery systems. Current Medicinal Chemistry 2001; 8(9): 1123 - 36.
5. Xiao Q, Ju Y, Yang XP, et al. Electrospray ionization mass spectrometry of AZT H-phosphonates conjugated with steroids. Rapid Commun Mass Spectrom 2003; 17: 1405 - 10.
6. Yin W, Ma Y, and Zhao YF. The fragmentation mechanism of b-(Nalkyl/ arylamino)-a,b-unsaturated carboxylates under electrospray ionization conditions. Amino Acids 2006; 31: 333 - 6.
7. Ma Y, Liu W, Zhao YF. Intramolecular four-membered ring rearrangements of 1-(N-benzyloxycarbonylamino)arylmethyl phosphonate monoesters under electrospray ionization conditions. International Journal of Mass Spectrometry 2006; 248 (1 - 2): 17-20.
8. Cao SX, Liu HM, Xu W, et al. Characterizing the electrospray ionization mass spectral fragmentation pattern of indole derivatives synthesized from 2-keto glycosides. Journal of Mass Spectrometry 2005; 40(4): 452 - 7.
9. Ma Y, Liu W, Chen Y, Zhao YF. Ring contraction reactions of 2,3-dihydro-4H-1,3-oxazin-4-ones under electrospray ionization conditions. Rapid Commun Mass Spectrom 2004; 18: 1116 - 22.