Is there a role for scintigraphic imaging of bone manifestations in Gaucher disease? A review of the literature

NuklearMedizin

Volumn 47, Issue 6, 2008, Pages 239-247

  Mikosch, Peter ^a   Kohlfurst S ^a   Gallowitsch, H J ^a   Kresnik, E ^a   Lind, P ^a   Mehta, A B ^b   Hughes, D A ^b  

^a GENERAL HOSPITAL KLAGENFURT   (Austria)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Bone infarct; Bone marrow scintigraphy; Bone necrosis; Bone scintigraphy; Gaucher disease; Osteomyelitis

Indexed keywords

GLYCOLIPID; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; LEUKOCYTE IN 111; MEDRONATE TECHNETIUM TC 99M; TECHNETIUM SULFUR COLLOID TC 99M; XENON 133;

BONE MARROW SCINTISCANNING; BONE PAIN; BONE SCINTISCANNING; CLINICAL FEATURE; ENZYME REPLACEMENT; GAUCHER DISEASE; HUMAN; INTERMETHOD COMPARISON; OSTEOPENIA; POSITRON EMISSION TOMOGRAPHY; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

BONE DISEASES; BONE MARROW; GAUCHER DISEASE; HUMANS; MAGNETIC RESONANCE IMAGING; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M SESTAMIBI; TECHNETIUM TC 99M SULFUR COLLOID; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 57549091224     PISSN: 00295566     EISSN: None     Source Type: Journal    
DOI: 10.3413/nukmed-0142     Document Type: Review

References (41)

1. Aharoni D, Krausz Y, Elstein D et al. Tc-99m sestamibi bone marrow scintigraphy in Gaucher disease. Clin Nucl Med 2002; 27: 503-509.
2. Allen MJ, Meyer BJ, Khokher AM et al. Pro-inflammatory cytokines and the pathogenesis of Gaucher's disease: increased release of interleukin-6 and interleukin-10. Qu J Med 1997; 90: 19-25.
3. Babyn PS, Ranson M, McCarvile ME. Normal bone marrow: signal characteristics and fatty conversion. Magn Reson Imaging Clin N Am 1998; 6: 473-495.
4. Barak V, Acker M, Nisman B et al. Cytokines in Gaucher's disease. Eur Cytokine Netw 1999; 10: 205-210.
5. Bembi B, Ciana G, Mengel E et al. Bone complications in children with Gaucher disease. Br J Radiol 2002; 75 (Suppl 1): A137-A144.
6. Bilchik TR, Heyman S. Skeletal scintigraphy of pseudo-osteomyelitis in Gaucher's disease. Two case reports and a review of the literature. Clin Nucl Med 1992; 17: 279-282.
7. Blocklet D, Abramowicz M, Schoutens A. Bone, bone marrow, and MIBI scintigraphy findings in Gaucher's disease "bone crisis". Clin Nucl Med 2001; 26: 765-769.
8. Brady RO, Kanfer JN, Bradley RM et al. Demonstration of a deficiency of glucoceribroside-cleaving enzyme in Gaucher's disease. J Clin Invest 1966; 45: 1112-1115.
9. Braun HS, Nürnberg P, Tinschert S. Metaphyseal dysplasia: a new autosomal dominant type in a large German kindred. Am J Med Genet 2001; 101: 74-77.
10. Charrow J, Dulisse B, Grabowski GA et al. The effect of enzyme replacement therapy on bone crisis and bone pain in patients with type 1 Gaucher disease. Clin Genet 2007; 71: 205-211.
11. Cheng TH, Holman BL. Radionuclide assessment of Gaucher's disease. J Nucl Med 1978; 19: 1333-1336.
12. Demina A, Beutler E. Six new Gaucher disease mutations. Acta Haematol 1998; 99: 80-82.
13. Dolen EG, Berdon WE, Rzal-Shapiro C. "Cold bone scans" as a sign of hemorrhagic infarcts of the spine in Gaucher's disease. Pediatr Radiol 1997; 27: 514-516.
14. Farahati J, Trenn G, John-Mikolajewski V et al. Use of various diagnostic methods in a patient with Gaucher disease Type I. Clin Nucl Med 1996; 21: 619-625.
15. Germain DP. Gaucher's disease: a paradigm for interventional genetics. Clin Genet 2004; 65: 77-86.
16. Hermann G, Goldblatt J, Levy RN et al. Gaucher's disease type 1: Assessment of bone involvement by CT and scintigraphy. Am J Roentgenol 1986; 147: 943-948.
17. Hermann G, Pastores GM, Abdelwahab IF et al. Gaucher disease: assessment of skeletal involvement and therapeutic responses to enzyme replacement. Skeletal Radiol 1997; 26: 687-696.
18. Hollak CE, Evers L, Aerts JM et al. Elevated levels of M-CSF, sCD14 and IL8 in type 1 Gaucher disease. Blood Cells Mol Dis 1997; 23: 201-212.
19. Hollak CE, Pastores GM. Type I Gaucher disease. In: Zimran A (ed). Glycolipid storage disorders. Adis Communications 2004, Abington: 17-26.
20. Israel O, Jerushalmi, Front D. Scintigraphic findings in Gaucher's disease. J Nucl Med 1986; 27: 1557-1563.
21. Katz K, Mechlis-Frish S, Cohen IJ et al. Bone scans in the diagnosis of bone crisis in patients who have Gaucher disease. J Bone Joint Surg Am 1991; 73: 513-517.
22. La Civita L, Mariani G, Porciello G et al. Bone involvement in Gaucher's disease: "bone crisis" or disease complication? Clin Exp Rheumatol 1996; 14: 195-198.
23. Lorberboym M, Pastores GM, Kim CK et al. Scintigraphic monitoring of reticuloendothelial system in patients with type 1 Gaucher disease on enzyme replacement therapy. J Nucl Med 1997; 38: 890-895.
24. Maas M, Poll LW, Terk MR. Imaging and quantifying skeletal involvement in Gaucher disease. Br J Radiol 2002; 75 (Suppl 1): A13-A24.
25. 99mTc-sestamibi. J Nucl Med 2003; 44: 1253-1262.
26. 99mTc-HMPAO images in Gaucher's disease. Eur J Nucl Med 1996; 23: 466-470.
27. McHugh K, Olsen E ØE, Vellodi A. Gaucher disease in children: radiology of non-central nervous manifestations. Clin Radiol 2004; 59: 117-123.
28. Mistry PK, Wraight EP, Cox TM. Therapeutic delivery of proteins to macrophages: implications for treatment of Gaucher's disease. Lancet 1996; 348: 1555-1559.
29. Moore SG, Dawson KL. Red and yellow marrow in the femur: age-related changes in appearance at MR imaging. Radiology 1990; 175: 219-213.
30. Palestro CJ, Finn C. Indium-111-leucocyte imaging in Gaucher's disease. J Nucl Med 1993; 34: 818-820.
31. Pastores G, Wallenstein S, Desnick RJ et al. Bone density in Type 1 Gaucher disease. J Bone Min Res 1996; 11: 1801-1807.
32. Pastores GM, Hermann G, Norton KI et al. Regression of skeletal changes in type 1 Gaucher disease with enzyme replacement therapy. Skeletal Radiol 1996; 25: 485-488.
33. Rademakers RP. Radiologic evaluation of gaucher bone disease. Semin Haematol 1995 :32 (Suppl 1): 14-19.
34. Rao S, Solomon N, Millier S et al. Scintigraphic differentiation of bone infarction from osteomyelitis in children with sickle disease. J Pediatr 1985; 107: 685-688.
35. Rosenthal DI, Barton NW, McKusick KA et al. Quantitiative imaging of Gaucher disease. Radiology 1992; 185: 841-845.
36. Skaggs DL, Kim SK, Greene NW et al. Differentiation between bone infarction and acute osteomyelitis in children with sickle-cell disease with use of sequential radionuclide bone-marrow and bone scans. J Bone Joint Surg Am 2001; 83: 1810-1813.
37. Umans H, Haramati N, Flusser G. The diagnostic role of gadolinium enhanced MRI in distinguishing between acute medullary bone infarct and osteomyelitis. Magn Reson Imaging 2000; 18: 255-262.
38. Vom Dahl S, Poll L, Di Rocco M et al. Evidencebased recommendations for monitoring bone disease and the response to enzyme replacement therapy in Gaucher patients. Curr Med Res Opin 2006; 22: 1045-1064.
39. Weinreb N, Brady RO, Tappel AL. The lysosomal localization of spingolipid hydrolases. Biochim Biophys Acta 1968; 159: 141-146.
40. Wenstrup RJ, Roca-Espiau M, Weinreb NJ et al. Skeletal aspects of Gaucher disease: a review. Br J Radiol 2002; 75 (Suppl 1): A2-A12.
41. Zanzi I, Taylor S, Gould E et al. Scintigraphic and magnetic resonance studies in a patient with Gaucher's disease. Clin Nucl Med 1998; 13: 491-495.