메뉴 건너뛰기




Volumn 52, Issue 12, 2008, Pages 1507-1513

Transepithelial transport across Caco-2 cell monolayers of antihypertensive egg-derived peptides. PepT1-mediated flux of Tyr-Pro-Ile

Author keywords

Antihypertensive peptides; Caco 2 cells; Egg proteins; Intestinal transport

Indexed keywords

ANTIHYPERTENSIVE AGENT; COTRANSPORTER; EGG PROTEIN; OLIGOPEPTIDE; SLC15A1 PROTEIN, HUMAN;

EID: 57549088511     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200700503     Document Type: Article
Times cited : (110)

References (40)
  • 1
    • 33747503962 scopus 로고    scopus 로고
    • Bioactive peptides: Production and functionality
    • Korhonen, H., Pihlanto, A., Bioactive peptides: Production and functionality. Int. Dairy J. 2006, 16, 945-960.
    • (2006) Int. Dairy J , vol.16 , pp. 945-960
    • Korhonen, H.1    Pihlanto, A.2
  • 2
    • 6944221879 scopus 로고    scopus 로고
    • Bioavailability of angiotensin I converting enzyme inhibitory peptides
    • Vermeirssen, V., Van Camp, J., Verstraete, W., Bioavailability of angiotensin I converting enzyme inhibitory peptides. Br. J. Nutr. 2004, 92, 357-366.
    • (2004) Br. J. Nutr , vol.92 , pp. 357-366
    • Vermeirssen, V.1    Van Camp, J.2    Verstraete, W.3
  • 3
    • 0037501466 scopus 로고    scopus 로고
    • The impact of fermentation and in vitro digestion on the formation of angiotensin-I-converting enzyme inhibitory activity from pea and whey protein
    • Vermeirssen, V., Van Camp, J., Decroos, K., Van Wijmelbeke, L., Verstraete, W., The impact of fermentation and in vitro digestion on the formation of angiotensin-I-converting enzyme inhibitory activity from pea and whey protein. J. Dairy Sci. 2003, 86, 429-438.
    • (2003) J. Dairy Sci , vol.86 , pp. 429-438
    • Vermeirssen, V.1    Van Camp, J.2    Decroos, K.3    Van Wijmelbeke, L.4    Verstraete, W.5
  • 4
    • 33646798115 scopus 로고    scopus 로고
    • Antihypertensive peptides from egg white proteins
    • Aleixandre, A., Miguel, M., Antihypertensive peptides from egg white proteins. J. Nutr. 2006, 136, 1457-1460.
    • (2006) J. Nutr , vol.136 , pp. 1457-1460
    • Aleixandre, A.1    Miguel, M.2
  • 5
    • 0036195746 scopus 로고    scopus 로고
    • Intestinal transport of the lactokinin Ala-Leu-ProMet-His-Ile-Arg through a Caco-2 monolayer
    • Vermeirssen, V., Deplancke, B., Tappenden, K.-A., Van Camp, J. et al., Intestinal transport of the lactokinin Ala-Leu-ProMet-His-Ile-Arg through a Caco-2 monolayer. J. Pept. Sci. 2002, 8, 95-100.
    • (2002) J. Pept. Sci , vol.8 , pp. 95-100
    • Vermeirssen, V.1    Deplancke, B.2    Tappenden, K.-A.3    Van Camp, J.4
  • 6
    • 0034633086 scopus 로고    scopus 로고
    • Bioactive peptides derived from bovine whey proteins: Opioid and ACE-inhibitory peptides
    • Pihlanto-Leppälä, A., Bioactive peptides derived from bovine whey proteins: Opioid and ACE-inhibitory peptides. Trends Food Sci. Technol. 2001, 11, 347-356.
    • (2001) Trends Food Sci. Technol , vol.11 , pp. 347-356
    • Pihlanto-Leppälä, A.1
  • 7
    • 0036018543 scopus 로고    scopus 로고
    • Transport of peptidomimetic drugs by the intestinal Di/tri-peptide transporter, PepT1
    • Brodin, B., Nielsen, C.-U., Steffansen, B., Frøkjaer, S., Transport of peptidomimetic drugs by the intestinal Di/tri-peptide transporter, PepT1. Pharmacol. Toxicol. 2002, 90, 285-296.
    • (2002) Pharmacol. Toxicol , vol.90 , pp. 285-296
    • Brodin, B.1    Nielsen, C.-U.2    Steffansen, B.3    Frøkjaer, S.4
  • 8
    • 0028197288 scopus 로고
    • Absorption of peptide and peptidomimetic drugs
    • Amidon, G.-L., Lee, H.-J., Absorption of peptide and peptidomimetic drugs. Annu. Rev. Pharmacol. Toxicol. 1994, 34, 321-341.
    • (1994) Annu. Rev. Pharmacol. Toxicol , vol.34 , pp. 321-341
    • Amidon, G.-L.1    Lee, H.-J.2
  • 9
    • 0034825921 scopus 로고    scopus 로고
    • Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: Uptake and transport of fosinopril in cell cultures
    • Shu, C., Shen, H., Hopfer, U., Smith, D.-E., Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: Uptake and transport of fosinopril in cell cultures. Drug Metab. Dispos. 2001, 29, 1307-1315.
    • (2001) Drug Metab. Dispos , vol.29 , pp. 1307-1315
    • Shu, C.1    Shen, H.2    Hopfer, U.3    Smith, D.-E.4
  • 10
    • 0036479384 scopus 로고    scopus 로고
    • Transepithelial transport of the bioactive tripeptide, Val-Pro-Pro, in human intestinal Caco-2 cell monolayers
    • Satake, M., Enjoh, M., Nakamura, Y., Takano, T., et al., Transepithelial transport of the bioactive tripeptide, Val-Pro-Pro, in human intestinal Caco-2 cell monolayers. Biosci. Biotechnol. Biochem. 2002, 66, 378-384.
    • (2002) Biosci. Biotechnol. Biochem , vol.66 , pp. 378-384
    • Satake, M.1    Enjoh, M.2    Nakamura, Y.3    Takano, T.4
  • 11
    • 0030469762 scopus 로고    scopus 로고
    • Antihypertensive peptides are present in aorta after oral administration of sour milk containing these peptides to spontaneously hypertensive rats
    • Masuda, O., Nakamura, Y., Takano, T., Antihypertensive peptides are present in aorta after oral administration of sour milk containing these peptides to spontaneously hypertensive rats. J. Nutr. 1996, 126, 3063-3068.
    • (1996) J. Nutr , vol.126 , pp. 3063-3068
    • Masuda, O.1    Nakamura, Y.2    Takano, T.3
  • 12
    • 0026530486 scopus 로고
    • Enhancement of polypeptide and protein absorption by macromolecular carriers via endocytosis and transcytosis
    • Shen, W. C., Wan, J., Ekrami, H., Enhancement of polypeptide and protein absorption by macromolecular carriers via endocytosis and transcytosis. Adv. Drug Deliv. Rev. 1992, 8, 93-113.
    • (1992) Adv. Drug Deliv. Rev , vol.8 , pp. 93-113
    • Shen, W.C.1    Wan, J.2    Ekrami, H.3
  • 14
    • 0030759649 scopus 로고    scopus 로고
    • Shimizu, M., Tsunogai, M., Arai, S., Transepithelial transport of oligopeptides in the human intestinal cell, Caco-2. Peptides 1997, 18, 681-687. Erratum in: Peptides 1998, 19, 791.
    • Shimizu, M., Tsunogai, M., Arai, S., Transepithelial transport of oligopeptides in the human intestinal cell, Caco-2. Peptides 1997, 18, 681-687. Erratum in: Peptides 1998, 19, 791.
  • 15
    • 0029095148 scopus 로고
    • Isolation and characterization of ovokinin, a bradykinin B1 agonist peptide derived from ovalbumin
    • Fujita, H., Usui, H., Kurahashi, K., Yoshikawa, M., Isolation and characterization of ovokinin, a bradykinin B1 agonist peptide derived from ovalbumin. Peptides 1995, 16, 785-790.
    • (1995) Peptides , vol.16 , pp. 785-790
    • Fujita, H.1    Usui, H.2    Kurahashi, K.3    Yoshikawa, M.4
  • 16
    • 4444253706 scopus 로고    scopus 로고
    • Angiotensin I-converting enzyme inhibitory activity of peptides derived from egg white proteins by enzymatic hydrolysis
    • Miguel, M., Recio, I., Gómez-Ruiz, J.-A., Ramos, M., López-Fandiño, R., Angiotensin I-converting enzyme inhibitory activity of peptides derived from egg white proteins by enzymatic hydrolysis. J. Food Prot. 2004, 67, 1914-1920.
    • (2004) J. Food Prot , vol.67 , pp. 1914-1920
    • Miguel, M.1    Recio, I.2    Gómez-Ruiz, J.-A.3    Ramos, M.4    López-Fandiño, R.5
  • 17
    • 27944465326 scopus 로고    scopus 로고
    • Short-term effect of egg-white hydrolysate products on the arterial blood pressure of hypertensive rats
    • Miguel, M., López-Fandiño, R., Ramos, M., Aleixandre, A., Short-term effect of egg-white hydrolysate products on the arterial blood pressure of hypertensive rats. Br. J. Nutr. 2005, 94, 731-737.
    • (2005) Br. J. Nutr , vol.94 , pp. 731-737
    • Miguel, M.1    López-Fandiño, R.2    Ramos, M.3    Aleixandre, A.4
  • 18
    • 33244487664 scopus 로고    scopus 로고
    • Effect of simulated gastrointestinal digestion on the antihypertensive properties of ACE-inhibitory peptides derived from ovalbumin
    • Miguel, M., Aleixandre, M.-A., Ramos, M., López-Fandiño, R., Effect of simulated gastrointestinal digestion on the antihypertensive properties of ACE-inhibitory peptides derived from ovalbumin. J. Agric. Food Chem. 2006, 54, 726-731.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 726-731
    • Miguel, M.1    Aleixandre, M.-A.2    Ramos, M.3    López-Fandiño, R.4
  • 20
    • 33745647021 scopus 로고    scopus 로고
    • Specific effects of denaturation, hydrolysis and exposure to Lactococcus lactis on bovine beta-lactoglobulin transepithelial transport, antigenicity and allergenicity
    • Bernasconi, E., Fritsche, R., Corthesy, B., Specific effects of denaturation, hydrolysis and exposure to Lactococcus lactis on bovine beta-lactoglobulin transepithelial transport, antigenicity and allergenicity. Clin. Exp. Allergy 2006, 36, 803-814.
    • (2006) Clin. Exp. Allergy , vol.36 , pp. 803-814
    • Bernasconi, E.1    Fritsche, R.2    Corthesy, B.3
  • 22
    • 2642581484 scopus 로고    scopus 로고
    • Interaction of ovokinin(2-7) with vascular bradykinin 2 receptors
    • Scruggs, P., Filipeanu, C.-M., Yang, J., Chang, J.-K., Dun, N.-J., Interaction of ovokinin(2-7) with vascular bradykinin 2 receptors. Regul. Pept. 2004, 120, 85-91.
    • (2004) Regul. Pept , vol.120 , pp. 85-91
    • Scruggs, P.1    Filipeanu, C.-M.2    Yang, J.3    Chang, J.-K.4    Dun, N.-J.5
  • 23
    • 0029442621 scopus 로고
    • Potentiation of the antihypertensive activity of orally administerd Ovokinin, a vasorelaxing peptide derived from ovalbumin, by emulsification in egg phosphatidyl-choline
    • Fujita, H., Sasaki, R., Yoshikawa, M., Potentiation of the antihypertensive activity of orally administerd Ovokinin, a vasorelaxing peptide derived from ovalbumin, by emulsification in egg phosphatidyl-choline. Biosci. Biotech. Biochem. 1995, 59, 2344-2345.
    • (1995) Biosci. Biotech. Biochem , vol.59 , pp. 2344-2345
    • Fujita, H.1    Sasaki, R.2    Yoshikawa, M.3
  • 24
    • 0033042906 scopus 로고    scopus 로고
    • A novel antihypertensive peptide derived from ovalbumin induces nitric oxide-mediated vasorelaxation in an isolated SHR mesenteric artery
    • Matoba, N., Usui, H., Fujita, H., Yoshikawa, M., A novel antihypertensive peptide derived from ovalbumin induces nitric oxide-mediated vasorelaxation in an isolated SHR mesenteric artery. FEBS Lett. 1999, 452, 181-184.
    • (1999) FEBS Lett , vol.452 , pp. 181-184
    • Matoba, N.1    Usui, H.2    Fujita, H.3    Yoshikawa, M.4
  • 25
    • 0027316815 scopus 로고
    • Effects of bradykinin on the canine proximal colon
    • Rangachari, P.-K., Berezin, M., Prior, T., Effects of bradykinin on the canine proximal colon. Regul. Pept. 1993, 46, 511-522.
    • (1993) Regul. Pept , vol.46 , pp. 511-522
    • Rangachari, P.-K.1    Berezin, M.2    Prior, T.3
  • 26
    • 36549037733 scopus 로고    scopus 로고
    • Transepithelial flux of HLPLP
    • Bioavailability of the antihypertensive peptide LHLPLP
    • Quirós, A., Dávalos, A., Lasunción, M.-A., Ramos, M., Recio, I., Bioavailability of the antihypertensive peptide LHLPLP: Transepithelial flux of HLPLP. Int. Dairy J. 2008, 18, 279-286.
    • (2008) Int. Dairy J , vol.18 , pp. 279-286
    • Quirós, A.1    Dávalos, A.2    Lasunción, M.-A.3    Ramos, M.4    Recio, I.5
  • 27
    • 11944257758 scopus 로고    scopus 로고
    • Efflux properties of basolateral peptide transporter in human intestinal cell line Caco-2
    • Irie, M., Terada, T., Okuda, M., Inui, K., Efflux properties of basolateral peptide transporter in human intestinal cell line Caco-2. Pflugers Arch. 2004, 449, 186-194.
    • (2004) Pflugers Arch , vol.449 , pp. 186-194
    • Irie, M.1    Terada, T.2    Okuda, M.3    Inui, K.4
  • 28
    • 0033042420 scopus 로고    scopus 로고
    • Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2
    • Terada, T., Sawada, K., Saito, H., Hashimoto, Y., Inui, K., Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2. Am. J. Physiol. 1999, 276, G1435-G1441.
    • (1999) Am. J. Physiol , vol.276
    • Terada, T.1    Sawada, K.2    Saito, H.3    Hashimoto, Y.4    Inui, K.5
  • 29
    • 0028905095 scopus 로고
    • Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2
    • Thwaites, D.-T., Cavet, M., Hirst, B.-H., Simmons, N.-L., Functional characteristics of basolateral peptide transporter in the human intestinal cell line Caco-2. Br. J. Pharmacol. 1995, 114, 981-986.
    • (1995) Br. J. Pharmacol , vol.114 , pp. 981-986
    • Thwaites, D.-T.1    Cavet, M.2    Hirst, B.-H.3    Simmons, N.-L.4
  • 30
    • 0037990704 scopus 로고    scopus 로고
    • Differential recognition of ACE inhibitors in Xenopus laevis oocytes expressing rat PEPT1 and PEPT2
    • Zhu, T., Chen, X.-Z., Steel, A., Hediger, M. A., Smith, D. E., Differential recognition of ACE inhibitors in Xenopus laevis oocytes expressing rat PEPT1 and PEPT2. Pharm. Res. 2000, 17, 526-532.
    • (2000) Pharm. Res , vol.17 , pp. 526-532
    • Zhu, T.1    Chen, X.-Z.2    Steel, A.3    Hediger, M.A.4    Smith, D.E.5
  • 31
    • 0022451875 scopus 로고
    • Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: Further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity
    • Madara, J.-L., Barenberg, D., Carlson, S., Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: Further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity. J. Cell Biol. 1986, 102, 2125-2136.
    • (1986) J. Cell Biol , vol.102 , pp. 2125-2136
    • Madara, J.-L.1    Barenberg, D.2    Carlson, S.3
  • 32
    • 0028862325 scopus 로고
    • Wortmannin, an inhibitor of phosphoinositide 3-kinase, inhibits transcytosis in polarized epithelial cells
    • Hansen, S.-H., Olsson, A., Casanova, J.-E., Wortmannin, an inhibitor of phosphoinositide 3-kinase, inhibits transcytosis in polarized epithelial cells. J. Biol. Chem. 1995, 270, 28425-28432.
    • (1995) J. Biol. Chem , vol.270 , pp. 28425-28432
    • Hansen, S.-H.1    Olsson, A.2    Casanova, J.-E.3
  • 33
    • 0025322615 scopus 로고
    • Glycyl-L-Proline transport in rabbit enterocyte basolateral-membrane vesicles
    • Dyer, J., Beechey, R. B., Gorvel, J.-P., Smith, R.-T., et al., Glycyl-L-Proline transport in rabbit enterocyte basolateral-membrane vesicles. Biochem. J. 1990, 269, 565-571.
    • (1990) Biochem. J , vol.269 , pp. 565-571
    • Dyer, J.1    Beechey, R.B.2    Gorvel, J.-P.3    Smith, R.-T.4
  • 34
    • 0027319297 scopus 로고
    • Dipeptide transporters in apical and basolateral membranes of the human intestinal cell line Caco-2
    • Saito, H., Inui, K., Dipeptide transporters in apical and basolateral membranes of the human intestinal cell line Caco-2. Am. J. Physiol. 1993, 265, G289-G294.
    • (1993) Am. J. Physiol , vol.265
    • Saito, H.1    Inui, K.2
  • 35
    • 0034570845 scopus 로고    scopus 로고
    • Grimble, G.-K., Mechanisms of peptide and amino acid transport and their regulation. in: Furst, P., Young, V. (Eds.), Proteins, Peptides and Amino Acids in Enteral Nutrition, Nestle Nutrition Workshop Series Clinical & Performance Program. Nestec Ltd., Basel, 2000, pp. 63-88.
    • Grimble, G.-K., Mechanisms of peptide and amino acid transport and their regulation. in: Furst, P., Young, V. (Eds.), Proteins, Peptides and Amino Acids in Enteral Nutrition, Nestle Nutrition Workshop Series Clinical & Performance Program. Nestec Ltd., Basel, 2000, pp. 63-88.
  • 36
    • 0001166311 scopus 로고
    • Transmembrane transport of small peptides
    • Bronner, F, Kleinzeller, A, Eds, Academic Press, New York
    • Matthews, D. M., Payne, J. W., Transmembrane transport of small peptides. in: Bronner, F., Kleinzeller, A. (Eds.), Current Topics in Membrane and Transport, Academic Press, New York 1980, pp. 331-425.
    • (1980) Current Topics in Membrane and Transport , pp. 331-425
    • Matthews, D.M.1    Payne, J.W.2
  • 37
    • 34447579220 scopus 로고    scopus 로고
    • Transport of a tripeptide, Gly-ProHyp, across the porcine intestinal brush-border membrane
    • Aito-Inoue, M., Lackeyram, D., Fan, M.-Z., Sato, K., Mine, Y., Transport of a tripeptide, Gly-ProHyp, across the porcine intestinal brush-border membrane. J. Pept. Sci. 2007, 13, 468-474.
    • (2007) J. Pept. Sci , vol.13 , pp. 468-474
    • Aito-Inoue, M.1    Lackeyram, D.2    Fan, M.-Z.3    Sato, K.4    Mine, Y.5
  • 38
    • 31344453213 scopus 로고    scopus 로고
    • In vitro intestinal transport and antihypertensive activity of ACE inhibitory pea and whey digests
    • Vermeirssen, V., Augustijns, P., Morel, N., Van Camp, J., et al., In vitro intestinal transport and antihypertensive activity of ACE inhibitory pea and whey digests. Int. J. Food Sci. Nutr. 2005, 56, 415-430.
    • (2005) Int. J. Food Sci. Nutr , vol.56 , pp. 415-430
    • Vermeirssen, V.1    Augustijns, P.2    Morel, N.3    Van Camp, J.4
  • 39
    • 57549112561 scopus 로고    scopus 로고
    • Correlation of in vitro and in vivo models for the oral absorption of peptide drugs
    • Föger, F., Kopf, A., Loretz, B., Albrecht, K., Bernkop- Schnürch, A., Correlation of in vitro and in vivo models for the oral absorption of peptide drugs. Amino Acids 2008, 348, 169-174.
    • (2008) Amino Acids , vol.348 , pp. 169-174
    • Föger, F.1    Kopf, A.2    Loretz, B.3    Albrecht, K.4    Bernkop- Schnürch, A.5
  • 40
    • 33748124256 scopus 로고    scopus 로고
    • Identification and characterization of novel angiotensin-onverting enzyme inhibitors obtained from goat milk
    • Geerlings, A., Villar, I.-C., Hidalgo Zarco, F., Sánchez, M. et al., Identification and characterization of novel angiotensin-onverting enzyme inhibitors obtained from goat milk. J. Dairy Sci. 2006, 89, 3326-3335.
    • (2006) J. Dairy Sci , vol.89 , pp. 3326-3335
    • Geerlings, A.1    Villar, I.-C.2    Hidalgo Zarco, F.3    Sánchez, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.