메뉴 건너뛰기




Volumn 5, Issue 12, 2008, Pages 2780-2792

Sexually dimorphic effects of testosterone administration on brain allopregnanolone in gonadectomized rats

Author keywords

Allopregnanolone; Gonadectomized Rats; Sex Dimorphism; Testosterone

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ANDROSTANOLONE; ESTRADIOL VALERATE; TESTOSTERONE;

EID: 57449112085     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2008.00999.x     Document Type: Article
Times cited : (8)

References (46)
  • 1
    • 0034913017 scopus 로고    scopus 로고
    • Behavioural effects of androgen in men and women
    • Christiansen K. Behavioural effects of androgen in men and women. J. Endocrinol 2001;170:39-48.
    • (2001) J. Endocrinol , vol.170 , pp. 39-48
    • Christiansen, K.1
  • 2
    • 26044461651 scopus 로고    scopus 로고
    • The endocrinology of sexual arousal
    • Bancroft J. The endocrinology of sexual arousal. J. Endocrinol 2005;186:411-27.
    • (2005) J. Endocrinol , vol.186 , pp. 411-427
    • Bancroft, J.1
  • 3
    • 33744721757 scopus 로고    scopus 로고
    • Testosterone and aggression: Berthold, birds and beyond
    • Soma KK. Testosterone and aggression: Berthold, birds and beyond. J. Neuroendocrinol 2006;18:543-51.
    • (2006) J. Neuroendocrinol , vol.18 , pp. 543-551
    • Soma, K.K.1
  • 4
    • 13844276633 scopus 로고    scopus 로고
    • Testosterone's anti-anxiety and analgesic effects may be due in part to actions of its 5alpha-reduced metabolites in the hippocampus
    • Edinger KL, Frye CA. Testosterone's anti-anxiety and analgesic effects may be due in part to actions of its 5alpha-reduced metabolites in the hippocampus. Psychoneuroendocrinology 2005;30:418-30.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 418-430
    • Edinger, K.L.1    Frye, C.A.2
  • 5
    • 33644558050 scopus 로고    scopus 로고
    • The role of androgens in cognition and brain aging in men
    • Janowsky JS. The role of androgens in cognition and brain aging in men. Neuroscience 2006;138:1015-20.
    • (2006) Neuroscience , vol.138 , pp. 1015-1020
    • Janowsky, J.S.1
  • 7
    • 33745790118 scopus 로고    scopus 로고
    • Testosterone replacement therapy for the treatment of neurological and neuropsychiatric disorders
    • Gold SM, Voskuhl RR. Testosterone replacement therapy for the treatment of neurological and neuropsychiatric disorders. Curr Opin Investig Drugs 2006;7:625-30.
    • (2006) Curr Opin Investig Drugs , vol.7 , pp. 625-630
    • Gold, S.M.1    Voskuhl, R.R.2
  • 8
    • 0035663215 scopus 로고    scopus 로고
    • The role of neurosteroids and non-genomic effects of progestins and androgens in mediating sexual receptivity of rodents
    • Frye CA. The role of neurosteroids and non-genomic effects of progestins and androgens in mediating sexual receptivity of rodents. Brain Res Brain Res Rev 2001;37:201-22.
    • (2001) Brain Res Brain Res Rev , vol.37 , pp. 201-222
    • Frye, C.A.1
  • 9
    • 0030007556 scopus 로고    scopus 로고
    • Ovarian steroids modify the behavioral and neurochemical responses of the central benzodiazepine receptor
    • Bitran D, Dowd JA. Ovarian steroids modify the behavioral and neurochemical responses of the central benzodiazepine receptor. Psychopharmacology 1996;125:65-73.
    • (1996) Psychopharmacology , vol.125 , pp. 65-73
    • Bitran, D.1    Dowd, J.A.2
  • 10
    • 33847150143 scopus 로고    scopus 로고
    • Self-administration of 3alpha-androstanediol increases locomotion and analgesia and decreases aggressive behavior of male hamsters
    • Frye CA, Babson A, Walf AA. Self-administration of 3alpha-androstanediol increases locomotion and analgesia and decreases aggressive behavior of male hamsters. Pharmacol Biochem Behav 2007;86:415-21.
    • (2007) Pharmacol Biochem Behav , vol.86 , pp. 415-421
    • Frye, C.A.1    Babson, A.2    Walf, A.A.3
  • 11
    • 3142634522 scopus 로고    scopus 로고
    • Testosterone metabolism in the hippocampus may mediate its anti-anxiety effects in male rats
    • Frye CA, Edinger KL. Testosterone metabolism in the hippocampus may mediate its anti-anxiety effects in male rats. Pharmacol Biochem Behav 2004;78:473-81.
    • (2004) Pharmacol Biochem Behav , vol.78 , pp. 473-481
    • Frye, C.A.1    Edinger, K.L.2
  • 12
    • 0030699924 scopus 로고    scopus 로고
    • Steroid metabolism in the mammalian brain: 5alpha-reduction and aromatization
    • Celotti F, Negri-Cesi P, Poletti A. Steroid metabolism in the mammalian brain: 5alpha-reduction and aromatization. Brain Res Bull 1997;44:365-75.
    • (1997) Brain Res Bull , vol.44 , pp. 365-375
    • Celotti, F.1    Negri-Cesi, P.2    Poletti, A.3
  • 14
    • 0026509649 scopus 로고
    • Neurosteroids: Endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance
    • Majewska MD. Neurosteroids: Endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance. Prog Neurobiol 1992;38:379.
    • (1992) Prog Neurobiol , vol.38 , pp. 379
    • Majewska, M.D.1
  • 15
    • 0032922384 scopus 로고    scopus 로고
    • Neuropsychopharmacological properties of neuroactive steroids
    • Rupprecht R, Holsboer F. Neuropsychopharmacological properties of neuroactive steroids. Steroids 1999;64:83-91.
    • (1999) Steroids , vol.64 , pp. 83-91
    • Rupprecht, R.1    Holsboer, F.2
  • 16
    • 0347418151 scopus 로고    scopus 로고
    • Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex
    • Djebaili M, Hoffman SW, Stein DG. Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex. Neuroscience 2004;123:349-59.
    • (2004) Neuroscience , vol.123 , pp. 349-359
    • Djebaili, M.1    Hoffman, S.W.2    Stein, D.G.3
  • 17
    • 12544255204 scopus 로고    scopus 로고
    • The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats
    • Djebaili M, Guo Q, Pettus EH, Hoffman SW, Stein DG. The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats. J Neurotrauma 2005;22:106-18.
    • (2005) J Neurotrauma , vol.22 , pp. 106-118
    • Djebaili, M.1    Guo, Q.2    Pettus, E.H.3    Hoffman, S.W.4    Stein, D.G.5
  • 18
    • 0041730324 scopus 로고    scopus 로고
    • Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum
    • Ghoumari AM, Ibanez C. Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum. J Neurochem 2003;86:848-59.
    • (2003) J Neurochem , vol.86 , pp. 848-859
    • Ghoumari, A.M.1    Ibanez, C.2
  • 19
    • 33644514957 scopus 로고    scopus 로고
    • 3-Hydroxy-5-Pregnan-20-One in the midbrain ventral tegmental area mediates social, sexual, and affective behaviors
    • Frye CA, Rhodes ME, Petralia SM, Walf AA, Sumida K, Edinger KL. 3-Hydroxy-5-Pregnan-20-One in the midbrain ventral tegmental area mediates social, sexual, and affective behaviors. Neuroscience 2006;138:1007-14.
    • (2006) Neuroscience , vol.138 , pp. 1007-1014
    • Frye, C.A.1    Rhodes, M.E.2    Petralia, S.M.3    Walf, A.A.4    Sumida, K.5    Edinger, K.L.6
  • 24
    • 13844307763 scopus 로고    scopus 로고
    • Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior
    • Pinna G, Costa E, Guidotti A. Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior. Proc Natl Acad Sci U S A 2005;102:2135-40.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2135-2140
    • Pinna, G.1    Costa, E.2    Guidotti, A.3
  • 25
    • 0033818180 scopus 로고    scopus 로고
    • Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression
    • Zhou J, Ng S, Adesanya-Famuiya O, Anderson K, Bondy CA. Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression. FASEB J 2000;14:1725-30.
    • (2000) FASEB J , vol.14 , pp. 1725-1730
    • Zhou, J.1    Ng, S.2    Adesanya-Famuiya, O.3    Anderson, K.4    Bondy, C.A.5
  • 26
    • 0037337028 scopus 로고    scopus 로고
    • MacLusky NJ Gonadal hormones affect spine synaptic density in the CA1 hippocampal subfield of male rats
    • Leranth C, Petnehazy O. MacLusky NJ Gonadal hormones affect spine synaptic density in the CA1 hippocampal subfield of male rats. J Neurosci 2003;23:1588-92.
    • (2003) J Neurosci , vol.23 , pp. 1588-1592
    • Leranth, C.1    Petnehazy, O.2
  • 27
    • 1642540035 scopus 로고    scopus 로고
    • Androgens increase spine synapse density in the CA1 hippocampal subfield of ovariectomized female rats
    • Leranth C, Hajszan T, MacLusky NJ. Androgens increase spine synapse density in the CA1 hippocampal subfield of ovariectomized female rats. J Neurosci 2004;24:495-9.
    • (2004) J Neurosci , vol.24 , pp. 495-499
    • Leranth, C.1    Hajszan, T.2    MacLusky, N.J.3
  • 28
    • 33846576950 scopus 로고    scopus 로고
    • Testosterone replacement increases vasodilatory reserve in androgen-deficient female rats
    • Cooper BC, Gokina NI, Osol G. Testosterone replacement increases vasodilatory reserve in androgen-deficient female rats. Fertil Steril 2007;87:422-5.
    • (2007) Fertil Steril , vol.87 , pp. 422-425
    • Cooper, B.C.1    Gokina, N.I.2    Osol, G.3
  • 29
    • 0025656531 scopus 로고
    • Neuroendocrine metabolism of progesterone and related progestins
    • Karavolas HJ, Hodges DR. Neuroendocrine metabolism of progesterone and related progestins. Ciba Found Symp 1990;153:22-44.
    • (1990) Ciba Found Symp , vol.153 , pp. 22-44
    • Karavolas, H.J.1    Hodges, D.R.2
  • 30
    • 0042209613 scopus 로고    scopus 로고
    • Differential regulation of steroid 5-reductase isozymes expression by androgens in the adult rat brain
    • Torres JM, Ortega E. Differential regulation of steroid 5-reductase isozymes expression by androgens in the adult rat brain. FASEB J 2003;17:1428-33.
    • (2003) FASEB J , vol.17 , pp. 1428-1433
    • Torres, J.M.1    Ortega, E.2
  • 32
    • 33646121282 scopus 로고    scopus 로고
    • Steroid 5alpha-reductase isozymes in the adult female rat brain: Central role of dihydrotestosterone
    • Torres JM, Ortega E. Steroid 5alpha-reductase isozymes in the adult female rat brain: Central role of dihydrotestosterone. J Mol Endocrinol 2006;36:239-45.
    • (2006) J Mol Endocrinol , vol.36 , pp. 239-245
    • Torres, J.M.1    Ortega, E.2
  • 33
    • 0031789616 scopus 로고    scopus 로고
    • Sexual differentiation of aromatase activity in the rat brain: Effects of perinatal steroid exposure
    • Roselli CE, Klosterman SA. Sexual differentiation of aromatase activity in the rat brain: Effects of perinatal steroid exposure. Endocrinology 1998;139:3193-201.
    • (1998) Endocrinology , vol.139 , pp. 3193-3201
    • Roselli, C.E.1    Klosterman, S.A.2
  • 34
    • 0023546559 scopus 로고
    • Genetic evidence for androgen-dependent and independent control of aromatase activity in the rat brain
    • Roselli CE, Salisbury RL, Resko JA. Genetic evidence for androgen-dependent and independent control of aromatase activity in the rat brain. Endocrinology 1987;121:2205-10.
    • (1987) Endocrinology , vol.121 , pp. 2205-2210
    • Roselli, C.E.1    Salisbury, R.L.2    Resko, J.A.3
  • 35
    • 34548446343 scopus 로고    scopus 로고
    • Brain aromatase: Roles in reproduction and neuroprotection
    • Roselli F. Brain aromatase: Roles in reproduction and neuroprotection. J Steroid Biochem Mol Biol 2007;106:143-50.
    • (2007) J Steroid Biochem Mol Biol , vol.106 , pp. 143-150
    • Roselli, F.1
  • 36
    • 0029760469 scopus 로고    scopus 로고
    • Sex differences in androgen regulated cytochrome P450 aromatase mRNA in the rat brain
    • Roselli CE, Abdelgadir SE, Jorgensen E, Resko JA. Sex differences in androgen regulated cytochrome P450 aromatase mRNA in the rat brain. Endocrine 1996;5:59-65.
    • (1996) Endocrine , vol.5 , pp. 59-65
    • Roselli, C.E.1    Abdelgadir, S.E.2    Jorgensen, E.3    Resko, J.A.4
  • 37
    • 0017624809 scopus 로고
    • Metabolism of [14C]Testosterone by human foetal and adult brain tissue
    • Jenkins JS, Hall CJ. Metabolism of [14C]Testosterone by human foetal and adult brain tissue. Endocrinol 1977;74:425-9.
    • (1977) Endocrinol , vol.74 , pp. 425-429
    • Jenkins, J.S.1    Hall, C.J.2
  • 43
    • 33645962531 scopus 로고    scopus 로고
    • Are androgens critical for penile erections in humans? Examining the clinical and preclinical evidence
    • Traish AM, Guay AT. Are androgens critical for penile erections in humans? Examining the clinical and preclinical evidence. J Sex Med 2006;3:382-404.
    • (2006) J Sex Med , vol.3 , pp. 382-404
    • Traish, A.M.1    Guay, A.T.2
  • 44
    • 33748102836 scopus 로고    scopus 로고
    • The effect of gonadal hormones and gender on anxiety and emotional learning
    • Toufexis DJ, Myers KM, Davis M. The effect of gonadal hormones and gender on anxiety and emotional learning. Horm Behav 2006;50:539-49.
    • (2006) Horm Behav , vol.50 , pp. 539-549
    • Toufexis, D.J.1    Myers, K.M.2    Davis, M.3
  • 45
    • 0026579057 scopus 로고
    • Neuroactive steroids
    • Paul SM, Purdy RH. Neuroactive steroids. FASEB J 1992;6:2311-22.
    • (1992) FASEB J , vol.6 , pp. 2311-2322
    • Paul, S.M.1    Purdy, R.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.