Effect of nifedipine on endothelial function in normotensive smokers: Potential contribution of increase in circulating hepatocyte growth factor

Journal of Human Hypertension

Volumn 18, Issue 10, 2004, Pages 701-705

  Yamasaki, K ^a   Aoki, M ^a   Makino, H ^a   Hashiya, N ^a   Shimizu, H ^a   Ohishi, M ^a   Ogihara, T ^a   Morishita, R ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Endothelial function; Forearm reactive hyperaemia; HGF; Nifedipine; Smoking

Indexed keywords

CALCIUM ANTAGONIST; GLYCERYL TRINITRATE; NIFEDIPINE; PLACEBO; SCATTER FACTOR;

ADULT; ARTICLE; ATHEROSCLEROSIS; BLOOD PRESSURE MEASUREMENT; CELL FUNCTION; CIGARETTE SMOKING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; ENDOTHELIUM LESION; FEMALE; FOREARM BLOOD FLOW; HEART RATE; HUMAN; HUMAN EXPERIMENT; HYPEREMIA; HYPERTENSION; MALE; MONOTHERAPY; PLETHYSMOGRAPHY; PROTEIN BLOOD LEVEL; RISK FACTOR; VASODILATATION;

ADULT; CALCIUM CHANNEL BLOCKERS; ENDOTHELIUM, VASCULAR; HEPATOCYTE GROWTH FACTOR; HUMANS; MALE; NIFEDIPINE; SMOKING; VASCULAR DISEASES;

EID: 5744253123     PISSN: 09509240     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jhh.1001727     Document Type: Article

References (29)

1. Kato J et al. Risk factors and predictors of coronary arterial lesions in Japanese hypertensive patients. Hypertens Res 2001; 24: 3-11.
2. Glantz SA, Parmley WW. Passive smoking and heart disease. Epidemiology, physiology, and biochemistry. Circulation 1991; 83 1-12.
3. Zembowicz A, Hatchett RJ, Radziszewski W, Gryglewski RJ. Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase. J Pharmacol Exp Ther 1993; 267: 1112-1118.
4. Benowitz NL. The role of nicotine in smoking-related cardiovascular disease. Prev Med 1997; 26: 412-417.
5. Czernin J et al. Effect of acute and long-term smoking on myocardial blood flow and flow reserve. Circulation 1995; 91 2891-2897.
6. Celermajer DS et al. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation 1993; 88: 2149-2155.
7. Barry J et al. Effect of smoking on the activity of ischemic heart disease. JAMA 1989; 261: 398-402.
8. Raij L, DeMaster EG, Jaimes EA. Cigarette smoke-induced endothelium dysfunction: role of superoxide anion. J Hypertens 2001; 19: 891-897.
9. Snajdar RM, Busuttil SJ, Averbook A, Graham DJ. Inhibition of endothelial cell migration by cigarette smoke condensate. J Surg Res 2001; 96: 10-16.
10. Mak IT, Boehme P, Weglicki WB. Antioxidant effects of calcium channel blockers against free radical injury in endothelial cells. Correlation of protection with preservation of glutathione levels. Circ Res 1992; 70: 1099-1103.
11. Betz E, Hammerle H, Strohschneider T. Inhibition of smooth muscle cell proliferation and endothelial permeability with flunarizine in vitro and in experimental atheroma. Res Exp Med (Berl) 1985; 185: 325-340.
12. Gunther J et al. Nitric oxide (EDRF) enhances the vasorelaxing effect of nitrendipine in various isolated arteries. Basic Res Cardiol 1992; 87: 452-460.
13. Lichtlen PR et al. Retardation of angiographic progression of coronary artery disease by nifedipine. Results of the International Nifedipine Trial on Antiatherosclerotic Therapy (INTACT). INTACT Group Investigators.. Lancet 1990; 335: 1109-1113.
14. Loaldi A et al. Comparison of nifedipine, propranolol and isosorbide dinitrate on angiographic progression and regression of coronary arterial narrowings in angina pectoris. Am J Cardiol 1989; 64: 433-439.
15. Hayashi S et al. Autocrine-paracrine effects of overexpression of hepatocyte growth factor gene on growth of endothelial cells. Biochem Biophys Res Commun 1996; 220: 539-545.
16. Nakamura Y et al. Hepatocyte growth factor is a novel member of the endothelium-specific growth factors: additive stimulatory effect of hepatocyte growth factor with basic fibroblast growth factor but not with vascular endothelial growth factor. J Hypertens 1996; 14: 1067-1072.
17. Iwatsubo H et al. Converting enzyme inhibitor improves forearm reactive hyperaemia in essential hypertension. Hypertension 1997; 29: 286-290.
18. Yamada A et al. Rapid and sensitive enzyme-linked immunosorbent assay for measurement of HGF in rat and human tissues. Biomed Res 1995; 16: 105-114.
19. Nakamura T. Structure and function of hepatocyte growth factor. Prog Growth Factor Res 1991; 3: 67-86.
20. Boros P, Miller CM. Hepatocyte growth factor: a multifunctional cytokine. Lancet 1995; 345: 293-295.
21. Tare M et al. Hyperpolarization and relaxation of atrial smooth muscle caused by nitric oxide derived from the endothelium. Nature 1990; 346: 69-71.
22. Suga S et al. Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-β. Possible existence of 'A vascular natriuretic peptide system'. J Clin Invest 1992; 90: 1145-1149.
23. Dzau VJ. The role of mechanical and humoral factors in growth regulation of vascular smooth muscle cells and cardiac myocytes. Curr Opin Nephrol Hypertens 1993; 2: 27-32.
24. Nakamura Y et al. Expression of local hepatocyte growth factor system in vascular tissues. Biochem Biophys Res Commun 1995; 215: 483-488.
25. Nakano N et al. Increased serum hepatocyte growth factor (HGF) and 13 decreased local HGF in spontaneously hypertensive rats. (abstract) J Hypertens 1996; 14: S67.
26. Hayashi K et al. In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model. Gene Therapy 2000; 7: 1664-1671.
27. Aoki M et al. Inhibition of neointimal formation after balloon injury by Cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model. Diabetologia 2001; 44: 1034-1042.
28. Hayashi S et al. Potential role of hepatocyte growth factor, a novel angiogenic growth factor, in peripheral arterial disease: downregulation of HGF in response to hypoxia in vascular cells. Circulation 1999; 100(Suppl II): II-301-II-308.
29. Morishita R et al. Potential role of endothelium-specific growth factor, hepatocyte growth factor, on endothelial damage in diabetes mellitus. Diabetes 1997; 46: 138-142.