Ribosome affinity and the prolonged molecular postantibiotic effect of cethromycin (ABT-773) in Haemophilus influenzae

International Journal of Antimicrobial Agents

Volumn 24, Issue 4, 2004, Pages 362-368

  Cao, Zhensheng ^a   Zhong, Ping ^a   Ruan, Xiaoan ^a   Merta, Phil ^a   Capobianco, John O ^a   Flamm, Robert K ^a   Nilius, Angela M ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

ABT 773; Cethromycin; Haemophilus influenzae; MIC; minimum inhibitory concentration; PAE; Postantibiotic effect; postantibiotic effect; Ribosome binding

Indexed keywords

11 AMINO 11 DEOXY 5 O DESOSAMINYL 3 OXO 6 O [3 (3 QUINOLYL)ALLYL] ERYTHRONOLIDE A 11,12 CYCLIC CARBAMATE; CETHROMYCIN; ERYTHROMYCIN; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CONTROLLED STUDY; DISSOCIATION; DRUG BINDING; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; HAEMOPHILUS INFLUENZAE TYPE A; NONHUMAN; POSTANTIBIOTIC EFFECT; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RIBOSOME;

ANTI-BACTERIAL AGENTS; ERYTHROMYCIN; GENE EXPRESSION REGULATION, BACTERIAL; HAEMOPHILUS INFLUENZAE; HUMANS; KETOLIDES; PROTEIN BIOSYNTHESIS; RIBOSOMES; RNA, RIBOSOMAL, 23S; TRANSCRIPTION, GENETIC;

EID: 5744239021     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2004.04.013     Document Type: Article

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