메뉴 건너뛰기




Volumn 93, Issue 12, 2008, Pages 4664-4671

Effects of the selective progesterone receptor modulator asoprisnil on uterine artery blood flow, ovarian activity, and clinical symptoms in patients with uterine leiomyomata scheduled for hysterectomy

Author keywords

[No Author keywords available]

Indexed keywords

ASOPRISNIL; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; PROGESTERONE RECEPTOR MODULATOR; TRANEXAMIC ACID;

EID: 57349169309     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-1104     Document Type: Article
Times cited : (90)

References (33)
  • 1
    • 0035956680 scopus 로고    scopus 로고
    • Uterine fibroids
    • Stewart EA 2001 Uterine fibroids. Lancet 357:293-298
    • (2001) Lancet , vol.357 , pp. 293-298
    • Stewart, E.A.1
  • 2
    • 0037677597 scopus 로고    scopus 로고
    • Etiology and pathogenesis of uterine leiomyomas: A review
    • Flake GP, Andersen J, Dixon D 2003 Etiology and pathogenesis of uterine leiomyomas: a review. Environ Health Perspect 111:1037-1054
    • (2003) Environ Health Perspect , vol.111 , pp. 1037-1054
    • Flake, G.P.1    Andersen, J.2    Dixon, D.3
  • 3
    • 21244463072 scopus 로고    scopus 로고
    • Hysterectomy for benign conditions
    • Edozien LC 2005 Hysterectomy for benign conditions. BMJ 330:1457-1458
    • (2005) BMJ , vol.330 , pp. 1457-1458
    • Edozien, L.C.1
  • 6
    • 0033664553 scopus 로고    scopus 로고
    • Advances in uterine leiomyoma research: The progesterone hypothesis
    • Rein MS 2000 Advances in uterine leiomyoma research: the progesterone hypothesis. Environ Health Perspect 108(Suppl 5):791-793
    • (2000) Environ Health Perspect , vol.108 , Issue.SUPPL. 5 , pp. 791-793
    • Rein, M.S.1
  • 8
    • 0027273447 scopus 로고
    • A prospective, randomized trial of gonadotropin-releasing hormone agonist plus estrogen-progestin or progestin "add-back" regimens for women with leiomyomata uteri
    • Friedman AJ, Daly M, Juneau-Norcross M, Rein MS, Fine C, Gleason R, Leboff M 1993 A prospective, randomized trial of gonadotropin-releasing hormone agonist plus estrogen-progestin or progestin "add-back" regimens for women with leiomyomata uteri. J Clin Endocrinol Metab 76:1439-1445
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 1439-1445
    • Friedman, A.J.1    Daly, M.2    Juneau-Norcross, M.3    Rein, M.S.4    Fine, C.5    Gleason, R.6    Leboff, M.7
  • 10
    • 0028199173 scopus 로고    scopus 로고
    • Reinsch RC, Murphy AA, Morales AJ, Yen SS 1994 The effects of RU 486 and leuprolide acetate on uterine artery blood flow in the fibroid uterus: a prospective, randomized study. Am J Obstet Gynecol 170:1623-1627; discussion 1627-1628
    • Reinsch RC, Murphy AA, Morales AJ, Yen SS 1994 The effects of RU 486 and leuprolide acetate on uterine artery blood flow in the fibroid uterus: a prospective, randomized study. Am J Obstet Gynecol 170:1623-1627; discussion 1627-1628
  • 11
    • 18844440705 scopus 로고    scopus 로고
    • Selective progesterone receptor modulator development and use in the treatment of leiomyomata and endometriosis
    • Chwalisz K, Perez MC, Demanno D, Winkel C, Schubert G, Elger W 2005 Selective progesterone receptor modulator development and use in the treatment of leiomyomata and endometriosis. Endocr Rev 26:423-438
    • (2005) Endocr Rev , vol.26 , pp. 423-438
    • Chwalisz, K.1    Perez, M.C.2    Demanno, D.3    Winkel, C.4    Schubert, G.5    Elger, W.6
  • 12
    • 14744294664 scopus 로고    scopus 로고
    • Discovery, chemistry, and reproductive pharmacology of asoprisnil and related 11β-benzaldoxime substituted selective progesterone receptor modulators (SPRMs)
    • Schubert G, Elger W, Kaufmann G, Schneider B, Reddersen G, Chwalisz K 2005 Discovery, chemistry, and reproductive pharmacology of asoprisnil and related 11β-benzaldoxime substituted selective progesterone receptor modulators (SPRMs). Semin Reprod Med 23:58-73
    • (2005) Semin Reprod Med , vol.23 , pp. 58-73
    • Schubert, G.1    Elger, W.2    Kaufmann, G.3    Schneider, B.4    Reddersen, G.5    Chwalisz, K.6
  • 13
    • 0033656617 scopus 로고    scopus 로고
    • Endocrine pharmacological characterization of progesterone antagonists and progesterone receptor modulators with respect to PR-agonistic and antagonistic activity
    • Elger W, Bartley J, Schneider B, Kaufmann G, Schubert G, Chwalisz K 2000 Endocrine pharmacological characterization of progesterone antagonists and progesterone receptor modulators with respect to PR-agonistic and antagonistic activity. Steroids 65:713-723
    • (2000) Steroids , vol.65 , pp. 713-723
    • Elger, W.1    Bartley, J.2    Schneider, B.3    Kaufmann, G.4    Schubert, G.5    Chwalisz, K.6
  • 14
    • 2542489158 scopus 로고    scopus 로고
    • Therapeutic potential for the selective progesterone receptor modulator asoprisnil in the treatment of leiomyomata
    • Chwalisz K, DeManno D, Garg R, Larsen L, Mattia-Goldberg C, Stickler T 2004 Therapeutic potential for the selective progesterone receptor modulator asoprisnil in the treatment of leiomyomata. Semin Reprod Med 22:113-119
    • (2004) Semin Reprod Med , vol.22 , pp. 113-119
    • Chwalisz, K.1    DeManno, D.2    Garg, R.3    Larsen, L.4    Mattia-Goldberg, C.5    Stickler, T.6
  • 15
    • 34249712002 scopus 로고    scopus 로고
    • A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata
    • Chwalisz K, Larsen L, Mattia-Goldberg C, Edmonds A, Elger W, Winkel CA 2007 A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata. Fertil Steril 87:1399-1412
    • (2007) Fertil Steril , vol.87 , pp. 1399-1412
    • Chwalisz, K.1    Larsen, L.2    Mattia-Goldberg, C.3    Edmonds, A.4    Elger, W.5    Winkel, C.A.6
  • 16
    • 34447305522 scopus 로고    scopus 로고
    • The effects of the selective progesterone receptor modulator asoprisnil on the morphology of uterine tissues after 3 months treatment in patients with symptomatic uterine leiomyomata
    • Williams AR, Critchley HO, Osei J, Ingamells S, Cameron IT, Han C, Chwalisz K 2007 The effects of the selective progesterone receptor modulator asoprisnil on the morphology of uterine tissues after 3 months treatment in patients with symptomatic uterine leiomyomata. Hum Reprod 22:1696-1704
    • (2007) Hum Reprod , vol.22 , pp. 1696-1704
    • Williams, A.R.1    Critchley, H.O.2    Osei, J.3    Ingamells, S.4    Cameron, I.T.5    Han, C.6    Chwalisz, K.7
  • 17
    • 0030075768 scopus 로고    scopus 로고
    • Intraobserver reproducibility of transvaginal Doppler measurements in uterine and intraovarian arteries in regularly menstruating women
    • Tekay A, Jouppila P 1996 Intraobserver reproducibility of transvaginal Doppler measurements in uterine and intraovarian arteries in regularly menstruating women. Ultrasound Obstet Gynecol 7:129-134
    • (1996) Ultrasound Obstet Gynecol , vol.7 , pp. 129-134
    • Tekay, A.1    Jouppila, P.2
  • 18
    • 0034985080 scopus 로고    scopus 로고
    • Intraobserver reproducibility of Doppler measurements of uterine artery blood flow velocity in premenopausal women
    • Valentin L, Sladkevicius P, Bland M 2001 Intraobserver reproducibility of Doppler measurements of uterine artery blood flow velocity in premenopausal women. Ultrasound Obstet Gynecol 17:431-433
    • (2001) Ultrasound Obstet Gynecol , vol.17 , pp. 431-433
    • Valentin, L.1    Sladkevicius, P.2    Bland, M.3
  • 21
    • 0036155211 scopus 로고    scopus 로고
    • The UFS-QOL, a new disease-specific symptom and health-related quality of life questionnaire for leiomyomata
    • Spies JB, Coyne K, Guaou Guaou N, Boyle D, Skyrnarz-Murphy K, Gonzalves SM 2002 The UFS-QOL, a new disease-specific symptom and health-related quality of life questionnaire for leiomyomata. Obstet Gynecol 99:290-300
    • (2002) Obstet Gynecol , vol.99 , pp. 290-300
    • Spies, J.B.1    Coyne, K.2    Guaou Guaou, N.3    Boyle, D.4    Skyrnarz-Murphy, K.5    Gonzalves, S.M.6
  • 24
    • 0036149959 scopus 로고    scopus 로고
    • Daily low-dose mifepristone has contraceptive potential by suppressing ovulation and menstruation: A double-blind randomized control trial of 2 and 5 mg per day for 120 days
    • Brown A, Cheng L, Lin S, Baird DT 2002 Daily low-dose mifepristone has contraceptive potential by suppressing ovulation and menstruation: a double-blind randomized control trial of 2 and 5 mg per day for 120 days. J Clin Endocrinol Metab 87:63-70
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 63-70
    • Brown, A.1    Cheng, L.2    Lin, S.3    Baird, D.T.4
  • 27
    • 0033168326 scopus 로고    scopus 로고
    • Altered uterine artery blood flow impedance after danazol therapy: Possible mode of action in dysfunctional uterine bleeding
    • Pepper J, Dewart PJ, Oyesanya OA 1999 Altered uterine artery blood flow impedance after danazol therapy: possible mode of action in dysfunctional uterine bleeding. Fertil Steril 72:66-70
    • (1999) Fertil Steril , vol.72 , pp. 66-70
    • Pepper, J.1    Dewart, P.J.2    Oyesanya, O.A.3
  • 28
    • 33646067165 scopus 로고    scopus 로고
    • A novel selective progesterone receptor modulator asoprisnil (J867) inhibits proliferation and induces apoptosis in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells
    • Chen W, Ohara N, Wang J, Xu Q, Liu J, Morikawa A, Sasaki H, Yoshida S, Demanno DA, Chwalisz K, Maruo T 2006 A novel selective progesterone receptor modulator asoprisnil (J867) inhibits proliferation and induces apoptosis in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells. J Clin Endocrinol Metab 91:1296-1304
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1296-1304
    • Chen, W.1    Ohara, N.2    Wang, J.3    Xu, Q.4    Liu, J.5    Morikawa, A.6    Sasaki, H.7    Yoshida, S.8    Demanno, D.A.9    Chwalisz, K.10    Maruo, T.11
  • 29
    • 38749121786 scopus 로고    scopus 로고
    • Comparative effects of SPRM asoprisnil (J867) on proliferation, apoptosis, and the expression of growth factors in cultured uterine leiomyoma cells and normal myometrial cells
    • Ohara N, Morikawa A, Chen W, Wang J, DeManno DA, Chwalisz K, Maruo T 2007 Comparative effects of SPRM asoprisnil (J867) on proliferation, apoptosis, and the expression of growth factors in cultured uterine leiomyoma cells and normal myometrial cells. Reprod Sci 14:20-27
    • (2007) Reprod Sci , vol.14 , pp. 20-27
    • Ohara, N.1    Morikawa, A.2    Chen, W.3    Wang, J.4    DeManno, D.A.5    Chwalisz, K.6    Maruo, T.7
  • 30
    • 0027278471 scopus 로고
    • An evaluation of the effect of gonadotropin-releasing hormone analogs and medroxyprogesterone acetate on uterine leiomyomata volume by magnetic resonance imaging: A prospective, randomized, double blind, placebo-controlled, crossover trial
    • Carr BR, Marshburn PB, Weatherall PT, Bradshaw KD, Breslau NA, Byrd W, Roark M, Steinkampf MP 1993 An evaluation of the effect of gonadotropin-releasing hormone analogs and medroxyprogesterone acetate on uterine leiomyomata volume by magnetic resonance imaging: a prospective, randomized, double blind, placebo-controlled, crossover trial. J Clin Endocrinol Metab 76:1217-1223
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 1217-1223
    • Carr, B.R.1    Marshburn, P.B.2    Weatherall, P.T.3    Bradshaw, K.D.4    Breslau, N.A.5    Byrd, W.6    Roark, M.7    Steinkampf, M.P.8
  • 31
    • 18744409835 scopus 로고    scopus 로고
    • The effects of 1-month administration of asoprisnil (J867), a selective progesterone receptor modulator, in healthy premenopausal women
    • Chwalisz K, Elger W, Stickler T, Mattia-Goldberg C, Larsen L 2005 The effects of 1-month administration of asoprisnil (J867), a selective progesterone receptor modulator, in healthy premenopausal women. Hum Reprod 20:1090-1099
    • (2005) Hum Reprod , vol.20 , pp. 1090-1099
    • Chwalisz, K.1    Elger, W.2    Stickler, T.3    Mattia-Goldberg, C.4    Larsen, L.5
  • 32
    • 0024993499 scopus 로고
    • Efficacy and safety considerations in women with uterine leiomyomas treated with gonadotropin-releasing hormone agonists: The estrogen threshold hypothesis
    • Friedman AJ, Lobel SM, Rein MS, Barbieri RL 1990 Efficacy and safety considerations in women with uterine leiomyomas treated with gonadotropin-releasing hormone agonists: the estrogen threshold hypothesis. Am J Obstet Gynecol 163:1114-1119
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 1114-1119
    • Friedman, A.J.1    Lobel, S.M.2    Rein, M.S.3    Barbieri, R.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.