Endocrine pharmacological characterization of progesterone antagonists and progesterone receptor modulators with respect to PR-agonistic and antagonistic activity

Steroids

Volumn 65, Issue 10-11, 2000, Pages 713-723

  Elger, Walter ^a   Bartley, Julia ^b   Schneider, Birgitt ^a   Kaufmann, Günther ^c   Schubert, Gerd ^c   Chwalisz, Kristof ^c  

^a EnTec GmbH   (Germany)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c BAYER PHARMA AG   (Germany)

Author keywords

Animal models; Comparative pharmacology; Endometrium; Mesoprogestins; Ovulation; PGF(2 ) secretion; Progesterone receptor modulators

Indexed keywords

11BETA (4 ACETYLPHENYL) 17BETA HYDROXY 17ALPHA (1,1,2,2,2 PENTAFLUOROETHYL)ESTRA 4,9 DIEN 3 ONE; ANTIGESTAGEN; ASOPRISNIL; HORMONE RECEPTOR AFFECTING AGENT; J 1042; J 912; J 956; MIFEPRISTONE; ONAPRISTONE; PROGESTERONE; PROGESTERONE RECEPTOR; PROGESTERONE RECEPTOR MODULATOR; PROMEGESTONE; PROSTAGLANDIN F2 ALPHA; UNCLASSIFIED DRUG; ZK 137316;

ABORTION; ANIMAL EXPERIMENT; ANIMAL MODEL; BIOASSAY; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENDOMETRIUM CELL; FEMALE; GUINEA PIG; LABOR INDUCTION; LUTEOLYSIS; MENSTRUATION; MONKEY; NONHUMAN; OVULATION INHIBITION; PREGNANCY; PROGESTERONE RELEASE; PROSTAGLANDIN RELEASE; RABBIT; RAT;

ABORTION, INDUCED; ANIMALS; DRUG EVALUATION, PRECLINICAL; ENDOCRINE SYSTEM; FEMALE; GUINEA PIGS; MODELS, ANIMAL; PREGNANCY; PREGNANCY RATE; PROGESTERONE; RABBITS; RECEPTORS, PROGESTERONE;

ANIMALIA; CAVIA; CAVIA PORCELLUS; ORYCTOLAGUS CUNICULUS; RODENTIA; SUS SCROFA;

EID: 0033656617     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(00)00178-1     Document Type: Conference Paper

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