Characterization of progesterone derivatives by LC-DAD-ESI/MSn and its application to the identification of impurities in flurogestone acetate

Chromatographia

Volumn 68, Issue 11-12, 2008, Pages 903-909

  Zhang, Yufeng ^a   Wang, Zunyuan ^b   Ma, Zhen ^b   Cheng, Yiyu ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Column liquid chromatography; Flurogestone acetate; Impurities; Progesterone derivatives; Tandem mass spectrometry

Indexed keywords

11,17 DIHYDROXYPROGESTONE; 16,17 EPOXY 11 HYDROXYPREGNA 1,4 DIENE 3,20 DIONE; 16,17 EPOXY 11 HYDROXYPROGESTERONE; 17 ACETOXY 6 METHYLPREGNA 4,6 DIENE 3,20 DIONE; 17 ACETYLOXYPREGNA 4,9(11) DIENE 3,20 DIONE; 17 HYDROXYPREGNA 4,6 DIENE 3,20 DIONE; 17 HYDROXYPREGNA 4,9(11) DIENE 3,20 DIONE; 9,11 EPOXY 17 ACETYLOXYPROGESTERONE; FLUGESTONE ACETATE; PROGESTERONE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMICAL BOND; DIODE ARRAY DETECTION; DRUG DEGRADATION; DRUG IMPURITY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRAVIOLET RADIATION;

EID: 57349169231     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1365/s10337-008-0838-5     Document Type: Article

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