Impact of contamination from scattered photons in singles-mode transmission data on quantitative small-animal PET imaging

Journal of Nuclear Medicine

Volumn 49, Issue 11, 2008, Pages 1852-1861

  Vandervoort, Eric ^a,b   Sossi, Vesna ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b OTTAWA REGIONAL CANCER CENTRE   (Canada)

Author keywords

Attenuation correction; Postinjection transmission; Quantitative PET; Singles mode transmission; Small animal PET

Indexed keywords

COBALT 57; FLUORODEOXYGLUCOSE F 18; GERMANIUM 68; GERMANIUM DERIVATIVE; LUTETIUM; LUTETIUM 176; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; AUTOANALYSIS; CONTROLLED STUDY; IMAGE RECONSTRUCTION; IMAGING SYSTEM; LIGHT SCATTERING; MACACA; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT;

ANIMALS; ARTIFACTS; INJECTIONS; PHANTOMS, IMAGING; PHOTONS; POSITRON-EMISSION TOMOGRAPHY; RATS;

EID: 57349162402     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.108.051193     Document Type: Article

References (20)

1. Smith R, Karp J, Muehllehner G, Gualtieri E, Benard F. Singles transmission scans performed post-injection for quantitative whole body PET imaging. IEEE Trans Nucl Sci. 1997;44:1329-1335.
2. Vandervoort E, Sossi V. An analytical scatter correction for singles-mode transmission data in PET. IEEE Trans Med Imaging. 2008;27:402-412.
3. Laforest R, Longford D, Siegel S, Newport DF, Yap J. Performance evaluation of the microPET® - FOCUS-F120. IEEE Trans Nucl Sci. 2007;54:42-49.
4. Kim JS, Lee JS, Im KC, et al. Performance measurement of the microPET focus 120 scanner. J Nucl Med. 2007;48:1527-1535.
5. Tai Y, Ruangma A, Rowland D, et al. Performance evaluation of the microPET Focus: a third generation microPET scanner dedicated to animal imaging. J Nucl Med. 2005;46:455-463.
6. Zaidi H, Diaz-Gomez M, Boudraa A, Slosman D. Fuzzy clustering-based segmented attenuation correction in whole-body PET imaging. Phys Med Biol. 2002;47:1143-1160.
7. Nuyts J, Dupont P, Stroobants S, Maes A, Mortelmans L, Suetens P. Evaluation of maximum-likelihood based attenuation correction in positron emission tomography. IEEE Trans Nucl Sci. 1999;46:1136-1141.
8. Daube-Witherspoon ME, Muehllehner G. Treatment of axial data in threedimensional PET. J Nucl Med. 1987;28:1717-1724.
9. Erdogan H, Fessler J. Ordered subsets algorithms for transmission tomography. Phys Med Biol. 1999;44:2835-2851.
10. Huber P. Robust Statistics, New York, NY: Wiley; 1981.
11. Watson CC. New, faster, image-based scatter correction for 3D PET. IEEE Trans Nucl Sci. 2000;47:1587-1594.
12. Vandervoort E, Camborde ML, Jan S, Sossi V. Monte Carlo modelling of singles-mode transmission data for small animal PET scanners. Phys Med Biol. 2007;52:3169-3184.
13. 18F-FDG microPET studies in mouse tumor xenografts. J Nucl Med. 2007;48:602-607.
14. Humm JL, Lee J, O'Donoghue J, et al. Changes in FDG tumor uptake during and after fractionated radiation therapy in a rodent tumor xenograft: the effects of stereotactic radiotherapy. Clin Positron Imaging. 1999;2:289-296.
15. Badawi RD, Miller M, Bailey DL, Marsden P. Developments in componentbased normalization for 3D PET. Phys Med Biol. 1999;44:571-594.
16. Defrise M, Kinahan P, Townsend D, Michel C, Sibomana M, Newport D. Exact and approximate rebinning algorithms for 3-D PET data. IEEE Trans Med Imaging. 1997;16:145-158.
17. Burger C, Goerres G, Schoenes S, Buck A, Lonn A, von Schulthess G. PET attenuation coefficients from CT images: experimental evaluation of the transformation of CT into PET 511-keV attenuation coefficients. Eur J Nucl Med Mol Imaging. 2002;29:922-927.
18. Bai C, Shao L, Silva AD, Zuo Z. A generalized model for the conversion from CT numbers to linear attenuation coefficients. IEEE Trans Nucl Sci. 2003;50:1510-1515.
19. Berger M, Hubbell J, Seltzer S, et al. XCOM: photon cross section database. Gaithersburg, MD: National Institute of Standards and Technology; 2006. Available at: http://physics.nist.gov/xcom. Accessed August 22, 2008
20. Hume SP, Meyers R, Bloomfield P, et al. Quantitation of carbon-11-labeled raclopride in rat striatum using positron emission tomography. Synapse. 1992;12:47-54.