Acetylation of Rsc4p by Gcn5p is essential in the absence of histone H3 acetylation

Molecular and Cellular Biology

Volumn 28, Issue 23, 2008, Pages 6967-6972

  Choi, Jennifer K ^a   Grimes, Daniel E ^a   Rowe, Keegan M ^a   Howe, LeAnn J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; FUNGAL PROTEIN; GLUTAMINE; HISTONE ACETYLTRANSFERASE; HISTONE H3; LYSINE; PROTEIN GCN5P; PROTEIN RSC4P; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ACETYLATION; AMINO ACID SUBSTITUTION; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ACETYLATION; AMINO ACID SUBSTITUTION; DNA-BINDING PROTEINS; FUNGAL PROTEINS; HISTONE ACETYLTRANSFERASES; HISTONES; MICROBIAL VIABILITY; PHENOTYPE; PROTEIN PROCESSING, POST-TRANSLATIONAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS;

EID: 57349156720     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00570-08     Document Type: Article

References (44)

1. Anderson, J. D., P. T. Lowary, and J. Widom. 2001. Effects of histone acetylation on the equilibrium accessibility of nucleosomal DNA target sites. J. Mol. Biol. 307:977-985.
2. Ausió, J., and K. E. van Holde. 1986. Histone hyperacetylation: its effects on nucleosome conformation and stability. Biochem. 25:1421-1428.
3. Ausubel, F. M. 1987. Current protocols in molecular biology. Greene Publishing Associates/Wiley-Interscience, New York, NY.
4. Babiarz, J. E., J. E. Halley, and J. Rine. 2006. Telomeric heterochromatin boundaries require NuA4-dependent acetylation of histone variant H2A. Z in Saccharomyces cerevisiae. Genes Dev. 20:700-710.
5. Balasubramanian, R., M. G. Pray-Grant, W. Selleck, P. A. Grant, and S. Tan. 2002. Role of the Ada2 and Ada3 transcriptional coactivators in histone acetylation. J. Biol. Chem. 277:7989-7995.
6. Bednar, J., R. A. Horowitz, S. A. Grigoryev, L. M. Carruthers, J. C. Hansen, A. J. Koster, and C. L. Woodcock. 1998. Nucleosomes, linker DNA, and linker histone form a unique structural motif that directs the higher-order folding and compaction of chromatin. Proc. Natl. Acad. Sci. USA 95:14173-14178.
7. Candau, R., J. X. Zhou, C. D. Allis, and S. L. Berger. 1997. Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo. EMBO J. 16:555-565.
8. Duina, A. A., and F. Winston. 2004. Analysis of a mutant histone H3 that perturbs the association of Swi/Snf with chromatin. Mol. Cell. Biol. 24:561-572.
9. Eberharter, A., D. E. Sterner, D. Schieltz, A. Hassan, J. R. Yates III, S. L. Berger, and J. L. Workman. 1999. The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae. Mol. Cell. Biol. 19:6621-6631.
10. Ferreira, H., A. Flaus, and T. Owen-Hughes. 2007. Histone modifications influence the action of Snf2 family remodeling enzymes by different mechanisms. J. Mol. Biol. 374:563-579.
11. Garcia-Ramirez, M., F. Dong, and J. Ausio. 1992. Role of the histone "tails" in the folding of oligonucleosomes depleted of histone H1. J. Biol. Chem. 267:19587-19595.
12. Georgakopoulos, T., N. Gounalaki, and G. Thireos. 1995. Genetic evidence for the interaction of the yeast transcriptional coactivator proteins GCN5 and ADA2. Mol. Gen. Genet. 246:723-728.
13. Grant, P. A., L. Duggan, J. Côté, S. M. Roberts, J. E. Brownell, R. Candau, R. Ohba, T. Owen-Hughes, C. D. Allis, F. Winston, S. L. Berger, and J. L. Workman. 1997. Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev. 11:1640-1650.
14. Grant, P. A., A. Eberharter, S. John, R. G. Cook, B. M. Turner, and J. L. Workman. 1999. Expanded lysine acetylation specificity of Gcn5 in native complexes. J. Biol. Chem. 274:5895-5900.
15. Howe, L., D. Auston, P. Grant, S. John, R. G. Cook, J. L. Workman, and L. Pillus. 2001. Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev. 15:3144-3154.
16. John, S., L. Howe, S. T. Tafrov, P. A. Grant, R. Sternglanz, and J. L. Workman. 2000. The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev. 14:1196-1208.
17. Kristjuhan, A., J. Walker, N. Suka, M. Grunstein, D. Roberts, B. R. Cairns, and J. Q. Svejstrup. 2002. Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region. Mol. Cell 10:925-933.
18. Kuo, M.-H., J. Zhou, P. Jambeck, M. E. A. Churchill, and C. D. Allis. 1998. Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo. Genes Dev. 12:627-639.
19. Lin, Y. Y., Y. Qi, J. Y. Lu, X. Pan, D. S. Yuan, Y. Zhao, J. S. Bader, and J. D. Boeke. 2008. A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev. 22:2062-2074.
20. Ling, X., T. A. A. Harkness, M. C. Schultz, G. Fisher-Adams, and M. Grunstein. 1996. Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene regulation. Genes Dev. 10:686-699.
21. Longtine, M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953-961.
22. Mann, M., S. E. Ong, M. Gronborg, H. Steen, O. N. Jensen, and A. Pandey. 2002. Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome. Trends Biotechnol. 20:261-268.
23. Martin, D. G. E., D. E. Grimes, K. Baetz, and Howe, L. 2006. Methylation of histone H3 mediates the association of the NuA3 histone acetyltransferase with chromatin. Mol. Biol. Cell 26:3018-3028.
24. Millar, C. B., F. Xu, K. Zhang, and M. Grunstein. 2006. Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast. Genes Dev. 20:711-722.
25. Morgan, B. A., B. A. Mittman, and M. M. Smith. 1991. The highly conserved N-terminal domains of histones H3 and H4 are required for normal cell cycle progression. Mol. Cell. Biol. 11:4111-4120.
26. Morris, S. A., B. Rao, B. A. Garcia, S. B. Hake, R. L. Diaz, J. Shabanowitz, D. F. Hunt, C. D. Allis, J. D. Lieb, and B. D. Strahl. 2007. Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. J. Biol. Chem. 282:7632-7640.
27. Patterton, H. G., C. C. Landel, D. Landsman, C. L. Peterson, and R. T. Simpson. 1998. The biochemical and phenotypic characterization of Hho1p, the putative linker histone H1 of Saccharomyces cerevisiae. J. Biol. Chem. 273:7268-7276.
28. Polevoda, B., and F. Sherman. 2002. The diversity of acetylated proteins. Genome Biol. 3:reviews0006.
29. Pollard, K. J., and C. L. Peterson. 1997. Role of ADA/GCN5 products in antagonizing chromatin-mediated transcriptional repression. Mol. Cell. Biol. 17:6212-6222.
30. Pray-Grant, M. G., D. Schieltz, S. J. McMahon, J. M. Wood, E. L. Kennedy, R. G. Cook, J. L. Workman, J. R. Yates III, and P. A. Grant. 2002. The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway. Mol. Cell. Biol. 22:8774-8786.
31. Puig, O., F. Caspary, G. Rigaut, B. Rutz, E. Bouveret, E. Bragado-Nilsson, M. Wilm, and B. Seraphin. 2001. The tandem affinity purification (TAP) method: a general procedure of protein complex purification. Methods 24:218-229.
32. Rosaleny, L. E., A. B. Ruiz-Garcia, J. Garcia-Martinez, J. E. Perez-Ortin, and V. Tordera. 2007. The Sas3p and Gcn5p histone acetyltransferases are recruited to similar genes. Genome Biol. 8:R119.
33. Shogren-Knaak, M., H. Ishii, J. M. Sun, M. J. Pazin, J. R. Davie, and C. L. Peterson. 2006. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science 311:844-847.
34. Simpson, R. T. 1978. Structure of chromatin containing extensively acetylated H3 and H4. Cell 13:691-699.
35. Spellman, P. T., G. Sherlock, M. Q. Zhang, V. R. Iyer, K. Anders, M. B. Eisen, P. O. Brown, D. Botstein, and B. Futcher. 1998. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol. Biol. Cell 9:3273-3297.
36. Sterner, D. E., R. Belotserkovskaya, and S. L. Berger. 2002. SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription. Proc. Natl. Acad. Sci. USA 99:11622-11627.
37. Suka, N., Y. Suka, A. A. Carmen, J. Wu, and M. Grunstein. 2001. Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin. Mol. Cell 8:473-479.
38. Syntichaki, P., and G. Thireos. 1998. The Gcn5-Ada complex potentiates the histone acetyltransferase activity of Gcn5. J. Biol. Chem. 273:24414-24419.
39. Toth, K., N. Brun, and J. Langowski. 2006. Chromatin compaction at the mononucleosome level. Biochemistry 45:1591-1598.
40. VanDemark, A. P., M. M. Kasten, E. Ferris, A. Heroux, C. P. Hill, and B. R. Cairns. 2007. Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation. Mol. Cell 27:817-828.
41. Wittschieben, B. O., G. Otero, T. de Bizemont, J. Fellows, H. Erdjument-Bromage, R. Ohba, Y. Li, C. D. Allis, P. Tempst, and J. Q. Svejstrup. 1999. A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme. Mol. Cell 4:123-128.
42. Yang, X. J. 2004. Lysine acetylation and the bromodomain: a new partnership for signaling. Bioessays 26:1076-1087.
43. Zanton, S. J., and B. F. Pugh. 2006. Full and partial genome-wide assembly and disassembly of the yeast transcription machinery in response to heat shock. Genes Dev. 20:2250-2265.
44. Zhang, W., J. R. Bone, D. G. Edmondson, B. M. Turner, and S. Y. Roth. 1998. Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase. EMBO J. 17:3155-3167.