Chlorpyrifos induces apoptosis in human T cells

Toxicology

Volumn 255, Issue 1-2, 2009, Pages 53-57

  Li, Qing ^a   Kobayashi, Maiko ^a   Kawada, Tomoyuki ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Annexin V; Apoptosis; Caspase 3; Chlorpyrifos; DNA fragmentation; Human Jurkat T cell

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 3 INHIBITOR; CHLORPYRIFOS; LIPOCORTIN 5;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CYTOTOXIC T LYMPHOCYTE; DNA FRAGMENTATION; DOSE TIME EFFECT RELATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INSECTICIDAL ACTIVITY; LEUKEMIA CELL LINE; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TOXICOLOGY;

ANNEXIN A5; APOPTOSIS; CASPASE 3; CELL DEATH; CHLORPYRIFOS; DNA; DNA FRAGMENTATION; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HUMANS; INDICATORS AND REAGENTS; INSECTICIDES; JURKAT CELLS; L-LACTATE DEHYDROGENASE; T-LYMPHOCYTES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 57349149007     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.10.003     Document Type: Article

References (27)

1. Berkson J. Patient statement: a canary's tale. Toxicol. Ind. Health 10 (1994) 323-326
2. Blakley B.R., Yole M.J., Brousseau P., Boermans H., and Fournier M. Effect of chlorpyrifos on immune function in rats. Vet. Hum. Toxicol. 41 (1999) 140-144
3. Caroline C. Insecticide fact sheet, Chlorpyrifos, part 1: Toxicology. J. pest. reform 14 (1994) 15-20
4. Caughlan A., Newhouse K., Namgung U., and Xia Z. Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. Toxicol. Sci. 78 (2004) 125-134
5. Dong C., Li Q., Lyu S.C., Krensky A.M., and Clayberger C. A novel apoptosis pathway activated by the carboxyl terminus of p21. Blood 105 (2005) 1187-1194
6. Ellenhorn M.J., and Barceloux D.G. Pesticides. In: Ellenhorn M.J., and Barceloux D.G. (Eds). Medical Toxicology (1988), Elsevier, New York 1069-1077 Chapter 38
7. Kim Y.M., Talanian R.V., and Billiar T.R. Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J. Biol. Chem. 272 (1997) 31138-31148
8. Lambeir A.M., Durinx C., Scharpe S., and De Meester I. Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV. Crit. Rev. Clin. Lab. Sci. 40 (2003) 209-294
9. Li Q., Hirata Y., Piao S., and Minami M. The by-products generated during sarin synthesis in the Tokyo sarin disaster induced inhibition of natural killer and cytotoxic T lymphocyte activity. Toxicology 146 (2000) 209-220
10. Li Q., Nagahara N., Takahashi H., Takeda K., Okumura K., and Minami M. Organophosphorus pesticides markedly inhibit the activities of natural killer, cytotoxic T lymphocyte and lymphokine-activated killer: a proposed inhibiting mechanism via granzyme inhibition. Toxicology 172 (2002) 181-190
11. Li Q., Nakadai A., Takeda K., and Kawada T. Dimethyl 2,2-dichlorovinyl phosphate (DDVP) markedly inhibits activities of natural killer cells, cytotoxic T lymphocytes and lymphokine-activated killer cells via the Fas-ligand/Fas pathway in perforin-knockout (PKO) mice. Toxicology 204 (2004) 41-50
12. Li Q., Nakadai A., Ishizaki M., Morimoto K., Ueda A., Krensky A.M., and Kawada T. Dimethyl 2,2-dichlorovinyl phosphate (DDVP) markedly decreases the expression of perforin, granzyme A and granulysin in human NK-92CI cell line. Toxicology 213 (2005) 107-116
13. Li Q., Dong C., Deng A., Katsumata M., Nakadai A., Kawada T., Okada S., Clayberger C., and Krensky A.M. Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin. Antimicrob. Agents Chemother. 49 (2005) 388-397
14. Li Q., and Kawada T. The new mechanism of organophosphorus pesticides-induced inhibition of cytolytic activity of killer cells. Cell. Mol. Immunol. (CMI) 3 (2006) 171-178
15. Li Q., Nakadai A., Matsushima H., Miyazaki Y., Krensky A.M., Kawada T., and Morimoto K. Phytoncides (wood essential oils) induce human natural killer cell activity. Immunopharmacol. Immunotoxicol. 28 (2006) 319-333
16. Li Q., Kobayashi M., and Kawada T. Organophosphorus pesticides induce apoptosis in human NK cells. Toxicology 239 (2007) 89-95
17. Li Q. New mechanism of organophosphorus pesticide-induced immunotoxicity. J Nippon Med. Sch. 74 (2007) 92-105
18. Li Q., Kobayashi M., and Kawada T. DDVP markedly decreases the expression of granzyme B and granzyme 3/K in human NK cells. Toxicology 243 (2008) 294-302
19. Nakadai A., Li Q., and Kawada T. Chlorpyrifos induces apoptosis in human monocyte cell line U937. Toxicology 224 (2006) 202-209
20. Okada S., Li Q., Whitin J.C., Clayberger C., and Krensky A.M. Intracellular mediators of granulysin-induced cell death. J. Immunol. 171 (2003) 2556-2562
21. Patel T., Gores G.J., and Kaufmann S.H. The role of proteases during apoptosis. FASEB. J. 10 (1996) 587-597
22. Richardson M.L. C309: Chlorpyrifos. In: Richardson M.L. (Ed). The Dictionary of Substances and Their Effects 2 (1993), The Royal Society of Chemistry, Cambridge 460-463
23. Saleh A.M., Vijayasarathy C., Masoud L., Kumar L., Shahin A., and Kambal A. Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways. Toxicol. Appl. Pharmacol. 190 (2003) 47-57
24. Thrasher J.D., Madison R., and Broughton A. Immunologic abnormalities in humans exposed to chlorpyrifos: preliminary observations. Arch. Environ. Health 48 (1993) 89-93
25. Thrasher J.D., Heuser G., and Broughton A. Immunological abnormalities in humans chronically exposed to chlorpyrifos. Arch. Environ. Health 57 (2002) 181-187
26. Youinou P., Jamin C., Pers J.O., Berthou C., Saraux A., and Renaudineau Y. B lymphocytes are required for development and treatment of autoimmune diseases. Ann. N. Y. Acad. Sci. 1050 (2005) 19-33
27. Ziem G., and McTamney J. Profile of patients with chemical injury and sensitivity. Environ. Health Perspect. 105 Suppl 2 (1997) 417-436