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The alcohol and carboxylic acid corresponding to the Cannizzaro products of the aldehydes used were detected by TLC and checked by NMR spectroscopy after separation by silica-gel column chromatography
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The alcohol and carboxylic acid corresponding to the Cannizzaro products of the aldehydes used were detected by TLC and checked by NMR spectroscopy after separation by silica-gel column chromatography.
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10
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57349144550
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3 (3 equiv) in EtOH at 40°C for 25 h in 77% yield.
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3 (3 equiv) in EtOH at 40°C for 25 h in 77% yield.
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11
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57349117948
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Cyclization between chalcone 6 and benzaldehyde 9a (10 equiv) did not occur with pyridine (5 equiv) in EtOH at 40°C.
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Cyclization between chalcone 6 and benzaldehyde 9a (10 equiv) did not occur with pyridine (5 equiv) in EtOH at 40°C.
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