Synthesis and properties of 3-acyl-γ-pyrones, a novel class of flavones and chromones

Tetrahedron Letters

Volumn 46, Issue 23, 2005, Pages 4119-4121

  Ganguly, A K ^a   Kaur, S ^a   Mahata, P K ^a   Biswas, D ^a   Pramanik, B N ^b   Chan, T M ^b  

^a STEVENS INSTITUTE OF TECHNOLOGY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Heterocycles; Synthesis

Indexed keywords

CHROMONE DERIVATIVE; FLAVONE; FLAVONOID; PYRONE DERIVATIVE;

ANTIOXIDANT ACTIVITY; ARTICLE; PRECURSOR; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

EID: 18844411635     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.04.010     Document Type: Article

References (10)

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6. C. Riva, C. De Toma, L. Donadd, C. Boi, R. Pennini, G. Motta, and A. Leonardi Synthesis 1997 195 and references cited therein
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8. 4 and evaporated under reduced pressure. The crude product was purified by silica-gel column chromatography using hexane-EtOAc (60:40) as eluent. The compound crystallised from hexane-dichloromethane or ethanol
9. NMR and high-resolution mass spectra of all the compounds described in this paper were consistent with the assigned structures. Assignments were further confirmed using HMBC, HSQC and COSY experiments
10. All compounds described in this paper were crystalline. Crystals were obtained from dichloromethane-hexane or ethanol. The melting points of compounds 9a, 9b, 9c, 9d, 9e, 9f, 9g, 9h, 9i, 10a, 10b, 11, 15a, 15b, 15c, 15d and 16 were 250-251, 144-145, 193-194, 224-225, 215-216, 304-305, 270-271, 121-122, 162-163, 241-242, 284-285, 151-152, 126-127, 100-102, 64-65, 132-133 and 150-151°C. Yields were indicated in the parenthesis