Radioprotective effects of fucoidan on bone marrow cells: Improvement of the cell survival and immunoreactivity

Journal of Veterinary Science

Volumn 9, Issue 4, 2008, Pages 359-365

  Byon, Yun Young ^a,b   Kim, Mi Hyoung ^a   Yoo, Eun Sook ^b   Hwang, Kyu Kye ^a   Jee, Youngheun ^a   Shin, Taekyun ^a   Joo, Hong Gu ^a  

^a Jeju National University   (South Korea)

^b Jeju National University School of Medicine   (South Korea)

Author keywords

Bone marrow cells; Fucoidan; Immunoreactivity; Radioprotection

Indexed keywords

FUCUS; FUCUS VESICULOSUS; PHAEOPHYCEAE;

EID: 57349129515     PISSN: 1229845X     EISSN: None     Source Type: Journal    
DOI: 10.4142/jvs.2008.9.4.359     Document Type: Article

References (22)

1. Arora R, Gupta D, Chawla R, Sagar R, Sharma A, Kumar R, Prasad J, Singh S, Samanta N, Sharma RK. Radioprotection by plant products: present status and future prospects. Phytother Res 2005, 19, 1-22.
2. Choi EM, Kim AJ, Kim YO, Hwang JK. Immunomodulating activity of arabinogalactan and fucoidan in vitro. J Med Food 2005, 8, 446-453.
3. Frenette PS, Weiss L. Sulfated glycans induce rapid hematopoietic progenitor cell mobilization: evidence for selectin-dependent and independent mechanisms. Blood 2000, 96, 2460-2468.
4. Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999, 13, 1899-1911.
5. Hosseinimehr SJ. Trends in the development of radioprotective agents. Drug Discov Today 2007, 12, 794-805.
6. Irhimeh MR, Fitton JH, Lowenthal RM. Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells. Exp Hematol 2007, 35, 989-994.
7. Ivanova T, Han Y, Son HJ, Yun YS, Song JY. Antimutagenic effect of polysaccharide ginsan extracted from Panax ginseng. Food Chem Toxicol 2006, 44, 517-521.
8. Joo HG, Goedegebuure PS, Sadanaga N, Nagoshi M, von Bernstorff W, Eberlein TJ. Expression and function of galectin-3, a β-galactoside- binding protein in activated T lymphocytes. J Leukoc Biol 2001, 69, 555-564.
9. Kim HJ, Kim MH, Byon YY, Park JW, Jee Y, Joo HG. Radioprotective effects of an acidic polysaccharide of Panax ginseng on bone marrow cells. J Vet Sci 2007, 8, 39-44.
10. Kim MH, Joo HG. Immunostimulatory effects of fucoidan on bone marrow-derived dendritic cells. Immunol Lett 2008, 115, 138-143.
11. Lake AC, Vassy R, Di Benedetto M, Lavigne D, Le Visage C, Perret GY, Letourneur D. Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1. J Biol Chem 2006, 281, 37844-37852.
12. Liston P, Fong WG, Korneluk RG. The inhibitors of apoptosis: there is more to life than Bcl2. Oncogene 2003, 22, 8568-8580.
13. Maruyama H, Tamauchi H, Iizuka M, Nakano T. The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu). Planta Med 2006, 72, 1415-1417.
14. Opferman JT, Korsmeyer SJ. Apoptosis in the development and maintenance of the immune system. Nat Immunol 2003, 4, 410-415.
15. Rades D, Fehlauer F, Bajrovic A, Mahlmann B, Richter E, Alberti W. Serious adverse effects of amifostine during radiotherapy in head and neck cancer patients. Radiother Oncol 2004, 70, 261-264.
16. Rothe M, Pan MG, Henzel WJ, Ayres TM, Goeddel DV. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 1995, 83, 1243-1252.
17. Santini V, Giles FJ. The potential of amifostine: from cytoprotectant to therapeutic agent. Haematologica 1999, 84, 1035-1042.
18. Subramanian M, Chintalwar GJ, Chattopadhyay S. Antioxidant and radioprotective properties of an Ocimum sanctum polysaccharide. Redox Rep 2005, 10, 257-264.
19. Sweeney EA, Lortat-Jacob H, Priestley GV, Nakamoto B, Papayannopoulou T. Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells. Blood 2002, 99, 44-51.
20. Uren AG, Pakusch M, Hawkins CJ, Puls KL, Vaux DL. Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc Natl Acad Sci USA 1996, 93, 4974-4978.
21. Wang ZW, Zhou JM, Huang ZS, Yang AP, Liu ZC, Xia YF, Zeng YX, Zhu XF. Aloe polysaccharides mediated radioprotective effect through the inhibition of apoptosis. J Radiat Res 2004, 45, 447-454.
22. Wrembel-Wargocka J, Jabłońska H, Chomiczewski K. Clinical use of amifostine (WR-2721) as a preparation protecting healthy tissues from the cytotoxic effects of chemotherapy and radiation therapy. Przegl Lek 1996, 53, 820-825.