-
1
-
-
0027983669
-
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
-
Cho Y., Gorina S., Jeffrey P.D., and Pavletich N.P. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science 265 (1994) 346-355
-
(1994)
Science
, vol.265
, pp. 346-355
-
-
Cho, Y.1
Gorina, S.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
4
-
-
34347233807
-
p53 in breast cancer: mutation and countermeasures
-
Kumar S., Walia V., Ray M., and Elble R.C. p53 in breast cancer: mutation and countermeasures. Front. Biosci. 12 (2007) 4168-4178
-
(2007)
Front. Biosci.
, vol.12
, pp. 4168-4178
-
-
Kumar, S.1
Walia, V.2
Ray, M.3
Elble, R.C.4
-
5
-
-
0037217682
-
Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides
-
Soussi T., and Beroud C. Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides. Hum. Mutat. 21 (2003) 192-200
-
(2003)
Hum. Mutat.
, vol.21
, pp. 192-200
-
-
Soussi, T.1
Beroud, C.2
-
6
-
-
0033108231
-
Roles of the functional loss of p53 and other genes in astrocytoma tumorigenesis and progression
-
Nozaki M., Tada M., Kobayashi H., Zhang C.L., Sawamura Y., Abe H., Ishii N., and Van Meir E.G. Roles of the functional loss of p53 and other genes in astrocytoma tumorigenesis and progression. Neuro-oncology 1 (1999) 124-137
-
(1999)
Neuro-oncology
, vol.1
, pp. 124-137
-
-
Nozaki, M.1
Tada, M.2
Kobayashi, H.3
Zhang, C.L.4
Sawamura, Y.5
Abe, H.6
Ishii, N.7
Van Meir, E.G.8
-
7
-
-
33646782954
-
p53 and disease: when the guardian angel fails
-
Royds J.A., and Iacopetta B. p53 and disease: when the guardian angel fails. Cell Death Differ. 13 (2006) 1017-1026
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1017-1026
-
-
Royds, J.A.1
Iacopetta, B.2
-
8
-
-
0030990910
-
Reappraisal of p53 mutations in human malignant astrocytic neoplasms by p53 functional assay: comparison with conventional structural analyses
-
Tada M., Iggo R.D., Waridel F., Nozaki M., Matsumoto R., Sawamura Y., Shinohe Y., Ikeda J., and Abe H. Reappraisal of p53 mutations in human malignant astrocytic neoplasms by p53 functional assay: comparison with conventional structural analyses. Mol. Carcinog. 18 (1997) 171-176
-
(1997)
Mol. Carcinog.
, vol.18
, pp. 171-176
-
-
Tada, M.1
Iggo, R.D.2
Waridel, F.3
Nozaki, M.4
Matsumoto, R.5
Sawamura, Y.6
Shinohe, Y.7
Ikeda, J.8
Abe, H.9
-
9
-
-
0029135340
-
bcl-2 inhibits wild-type p53-triggered apoptosis but not G1 cell cycle arrest and transactivation of WAF1 and bax
-
Wang Y., Okan I., Szekely L., Klein G., and Wiman K.G. bcl-2 inhibits wild-type p53-triggered apoptosis but not G1 cell cycle arrest and transactivation of WAF1 and bax. Cell Growth Differ. 6 (1995) 1071-1075
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 1071-1075
-
-
Wang, Y.1
Okan, I.2
Szekely, L.3
Klein, G.4
Wiman, K.G.5
-
10
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry W.S., Tokino T., Velculescu V.E., Levy D.B., Parsons R., Trent J.M., Lin D., Mercer W.E., Kinzler K.W., and Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell 75 (1993) 817-825
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
el-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
11
-
-
24744453768
-
Identification of novel p53 target genes in ionizing radiation response
-
Jen K.-Y., and Cheung V.G. Identification of novel p53 target genes in ionizing radiation response. Cancer Res. 65 (2005) 7666-7673
-
(2005)
Cancer Res.
, vol.65
, pp. 7666-7673
-
-
Jen, K.-Y.1
Cheung, V.G.2
-
12
-
-
0033991755
-
An overview of the cell cycle arrest protein, p21(WAF1)
-
Harada K., and Ogden G.R. An overview of the cell cycle arrest protein, p21(WAF1). Oral Oncol. 36 (2000) 3-7
-
(2000)
Oral Oncol.
, vol.36
, pp. 3-7
-
-
Harada, K.1
Ogden, G.R.2
-
13
-
-
10244226744
-
The effect of adenovirus expressing wild-type p53 on 5-fluorouracil chemosensitivity is related to p53 status in pancreatic cancer cell lines
-
Eisold S., Linnebacher M., Ryschich E., Antolovic D., Hinz U., Klar E., and Schmidt J. The effect of adenovirus expressing wild-type p53 on 5-fluorouracil chemosensitivity is related to p53 status in pancreatic cancer cell lines. World J. Gastroenterol. 10 (2004) 3583-3589
-
(2004)
World J. Gastroenterol.
, vol.10
, pp. 3583-3589
-
-
Eisold, S.1
Linnebacher, M.2
Ryschich, E.3
Antolovic, D.4
Hinz, U.5
Klar, E.6
Schmidt, J.7
-
14
-
-
0030020689
-
Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis
-
Gomez-Manzano C., Fueyo J., Kyritsis A.P., Steck P.A., Roth J.A., McDonnell T.J., Steck K.D., Levin V.A., and Yung W.K. Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis. Cancer Res. 56 (1996) 694-699
-
(1996)
Cancer Res.
, vol.56
, pp. 694-699
-
-
Gomez-Manzano, C.1
Fueyo, J.2
Kyritsis, A.P.3
Steck, P.A.4
Roth, J.A.5
McDonnell, T.J.6
Steck, K.D.7
Levin, V.A.8
Yung, W.K.9
-
15
-
-
4043126820
-
Differential activation of the Fas/CD95 pathway by Ad-p53 in human gliomas
-
Cerrato J.A., Khan T., Koul D., Lang F.F., Conrad C.A., Yung W.K.A., and Liu T.-J. Differential activation of the Fas/CD95 pathway by Ad-p53 in human gliomas. Int. J. Oncol. 24 (2004) 409-417
-
(2004)
Int. J. Oncol.
, vol.24
, pp. 409-417
-
-
Cerrato, J.A.1
Khan, T.2
Koul, D.3
Lang, F.F.4
Conrad, C.A.5
Yung, W.K.A.6
Liu, T.-J.7
-
16
-
-
0036173666
-
Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation
-
Shono T., Tofilon P.J., Schaefer T.S., Parikh D., Liu T.-J., and Lang F.F. Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation. Cancer Res. 62 (2002) 1069-1076
-
(2002)
Cancer Res.
, vol.62
, pp. 1069-1076
-
-
Shono, T.1
Tofilon, P.J.2
Schaefer, T.S.3
Parikh, D.4
Liu, T.-J.5
Lang, F.F.6
-
17
-
-
0031851002
-
Phenotypic alterations of small cell lung carcinoma induced by different levels of wild-type p53 expression
-
Adachi J., Ookawa K., Kohno T., Tomizawa Y., Tsuchida S., and Yokota J. Phenotypic alterations of small cell lung carcinoma induced by different levels of wild-type p53 expression. Cell Death Differ. 5 (1998) 148-155
-
(1998)
Cell Death Differ.
, vol.5
, pp. 148-155
-
-
Adachi, J.1
Ookawa, K.2
Kohno, T.3
Tomizawa, Y.4
Tsuchida, S.5
Yokota, J.6
-
18
-
-
0029802591
-
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
-
Chen X., Ko L.J., Jayaraman L., and Prives C. p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev. 10 (1996) 2438-2451
-
(1996)
Genes Dev.
, vol.10
, pp. 2438-2451
-
-
Chen, X.1
Ko, L.J.2
Jayaraman, L.3
Prives, C.4
-
20
-
-
1242343925
-
Tsga10 encodes a 65-kilodalton protein that is processed to the 27-kilodalton fibrous sheath protein
-
Modarressi M.H., Behnam B., Cheng M., Taylor K.E., Wolfe J., and van der Hoorn F.A. Tsga10 encodes a 65-kilodalton protein that is processed to the 27-kilodalton fibrous sheath protein. Biol. Reprod. 70 (2004) 608-615
-
(2004)
Biol. Reprod.
, vol.70
, pp. 608-615
-
-
Modarressi, M.H.1
Behnam, B.2
Cheng, M.3
Taylor, K.E.4
Wolfe, J.5
van der Hoorn, F.A.6
-
21
-
-
0842343437
-
Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins
-
Grill B., Wilson G.M., Zhang K.-X., Wang B., Doyonnas R., Quadroni M., and Schrader J.W. Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins. J. Immunol. 172 (2004) 2389-2400
-
(2004)
J. Immunol.
, vol.172
, pp. 2389-2400
-
-
Grill, B.1
Wilson, G.M.2
Zhang, K.-X.3
Wang, B.4
Doyonnas, R.5
Quadroni, M.6
Schrader, J.W.7
-
22
-
-
25444467166
-
Absence of caprin-1 results in defects in cellular proliferation
-
Wang B., David M.D., and Schrader J.W. Absence of caprin-1 results in defects in cellular proliferation. J. Immunol. 175 (2005) 4274-4282
-
(2005)
J. Immunol.
, vol.175
, pp. 4274-4282
-
-
Wang, B.1
David, M.D.2
Schrader, J.W.3
-
23
-
-
33947210861
-
Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs
-
Solomon S., Xu Y., Wang B., David M.D., Schubert P., Kennedy D., and Schrader J.W. Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs. Mol. Cell. Biol. 27 (2007) 2324-2342
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 2324-2342
-
-
Solomon, S.1
Xu, Y.2
Wang, B.3
David, M.D.4
Schubert, P.5
Kennedy, D.6
Schrader, J.W.7
-
24
-
-
0018945601
-
Identification of a cellular protein substrate phosphorylated by the avian sarcoma virus-transforming gene product
-
Erikson E., and Erikson R.L. Identification of a cellular protein substrate phosphorylated by the avian sarcoma virus-transforming gene product. Cell 21 (1980) 829-836
-
(1980)
Cell
, vol.21
, pp. 829-836
-
-
Erikson, E.1
Erikson, R.L.2
-
25
-
-
0036083696
-
Annexins: from structure to function
-
Gerke V., and Moss S.E. Annexins: from structure to function. Physiol. Rev. 82 (2002) 331-371
-
(2002)
Physiol. Rev.
, vol.82
, pp. 331-371
-
-
Gerke, V.1
Moss, S.E.2
-
26
-
-
0035966011
-
Neuritogenesis and the nerve growth factor-induced differentiation of PC-12 cells requires annexin II-mediated plasmin generation
-
Jacovina A.T., Zhong F., Khazanova E., Lev E., Deora A.B., and Hajjar K.A. Neuritogenesis and the nerve growth factor-induced differentiation of PC-12 cells requires annexin II-mediated plasmin generation. J. Biol. Chem. 276 (2001) 49350-49358
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 49350-49358
-
-
Jacovina, A.T.1
Zhong, F.2
Khazanova, E.3
Lev, E.4
Deora, A.B.5
Hajjar, K.A.6
-
27
-
-
16644384603
-
Annexin 2 expression is reduced in human osteosarcoma metastases
-
Gillette J.M., Chan D.C., and Nielsen-Preiss S.M. Annexin 2 expression is reduced in human osteosarcoma metastases. J. Cell. Biochem. 92 (2004) 820-832
-
(2004)
J. Cell. Biochem.
, vol.92
, pp. 820-832
-
-
Gillette, J.M.1
Chan, D.C.2
Nielsen-Preiss, S.M.3
-
28
-
-
0035418338
-
Loss of annexin II heavy and light chains in prostate cancer and its precursors
-
Chetcuti A., Margan S.H., Russell P., Mann S., Millar D.S., Clark S.J., Rogers J., Handelsman D.J., and Dong Q. Loss of annexin II heavy and light chains in prostate cancer and its precursors. Cancer Res. 61 (2001) 6331-6334
-
(2001)
Cancer Res.
, vol.61
, pp. 6331-6334
-
-
Chetcuti, A.1
Margan, S.H.2
Russell, P.3
Mann, S.4
Millar, D.S.5
Clark, S.J.6
Rogers, J.7
Handelsman, D.J.8
Dong, Q.9
-
29
-
-
0037435040
-
Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration
-
Liu J.-W., Shen J.-J., Tanzillo-Swarts A., Bhatia B., Maldonado C.M., Person M.D., Lau S.S., and Tang D.G. Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration. Oncogene 22 (2003) 1475-1485
-
(2003)
Oncogene
, vol.22
, pp. 1475-1485
-
-
Liu, J.-W.1
Shen, J.-J.2
Tanzillo-Swarts, A.3
Bhatia, B.4
Maldonado, C.M.5
Person, M.D.6
Lau, S.S.7
Tang, D.G.8
-
30
-
-
8044250876
-
A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease
-
Mackay E.A., Ehrhard A., Moniatte M., Guenet C., Tardif C., Tarnus C., Sorokine O., Heintzelmann B., Nay C., Remy J.M., Higaki J., Van Dorsselaer A., Wagner J., Danzin C., and Mamont P. A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease. Eur. J. Biochem. 244 (1997) 414-425
-
(1997)
Eur. J. Biochem.
, vol.244
, pp. 414-425
-
-
Mackay, E.A.1
Ehrhard, A.2
Moniatte, M.3
Guenet, C.4
Tardif, C.5
Tarnus, C.6
Sorokine, O.7
Heintzelmann, B.8
Nay, C.9
Remy, J.M.10
Higaki, J.11
Van Dorsselaer, A.12
Wagner, J.13
Danzin, C.14
Mamont, P.15
-
31
-
-
1342344183
-
Overexpression of cathepsin B correlates with angiogenesis in colon adenocarcinoma
-
Kruszewski W.J., Rzepko R., Wojtacki J., Skokowski J., Kopacz A., Jaskiewicz K., and Drucis K. Overexpression of cathepsin B correlates with angiogenesis in colon adenocarcinoma. Neoplasma 51 (2004) 38-43
-
(2004)
Neoplasma
, vol.51
, pp. 38-43
-
-
Kruszewski, W.J.1
Rzepko, R.2
Wojtacki, J.3
Skokowski, J.4
Kopacz, A.5
Jaskiewicz, K.6
Drucis, K.7
-
32
-
-
1842538729
-
Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis
-
Yanamandra N., Gumidyala K.V., Waldron K.G., Gujrati M., Olivero W.C., Dinh D.H., Rao J.S., and Mohanam S. Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis. Oncogene 23 (2004) 2224-2230
-
(2004)
Oncogene
, vol.23
, pp. 2224-2230
-
-
Yanamandra, N.1
Gumidyala, K.V.2
Waldron, K.G.3
Gujrati, M.4
Olivero, W.C.5
Dinh, D.H.6
Rao, J.S.7
Mohanam, S.8
-
33
-
-
2942718949
-
Inhibition of cathepsin B MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis
-
Lakka S.S., Gondi C.S., Yanamandra N., Olivero W.C., Dinh D.H., Gujrati M., and Rao J.S. Inhibition of cathepsin B MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis. Oncogene 23 (2004) 4681-4689
-
(2004)
Oncogene
, vol.23
, pp. 4681-4689
-
-
Lakka, S.S.1
Gondi, C.S.2
Yanamandra, N.3
Olivero, W.C.4
Dinh, D.H.5
Gujrati, M.6
Rao, J.S.7
-
34
-
-
3042551389
-
Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor antisense cathepsin B inhibits tumor growth invasion and angiogenesis in gliomas
-
Gondi C.S., Lakka S.S., Yanamandra N., Olivero W.C., Dinh D.H., Gujrati M., Tung C.H., Weissleder R., and Rao J.S. Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor antisense cathepsin B inhibits tumor growth invasion and angiogenesis in gliomas. Cancer Res. 64 (2004) 4069-4077
-
(2004)
Cancer Res.
, vol.64
, pp. 4069-4077
-
-
Gondi, C.S.1
Lakka, S.S.2
Yanamandra, N.3
Olivero, W.C.4
Dinh, D.H.5
Gujrati, M.6
Tung, C.H.7
Weissleder, R.8
Rao, J.S.9
-
35
-
-
0036754586
-
Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas
-
Mai J., Sameni M., Mikkelsen T., and Sloane B.F. Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas. Biol. Chem. 383 (2002) 1407-1413
-
(2002)
Biol. Chem.
, vol.383
, pp. 1407-1413
-
-
Mai, J.1
Sameni, M.2
Mikkelsen, T.3
Sloane, B.F.4
-
36
-
-
33750619248
-
Unique neuronal functions of cathepsin L and cathepsin B in secretory vesicles: biosynthesis of peptides in neurotransmission and neurodegenerative disease
-
Hook V.Y.H. Unique neuronal functions of cathepsin L and cathepsin B in secretory vesicles: biosynthesis of peptides in neurotransmission and neurodegenerative disease. Biol. Chem. 387 (2006) 1429-1439
-
(2006)
Biol. Chem.
, vol.387
, pp. 1429-1439
-
-
Hook, V.Y.H.1
-
37
-
-
0024322516
-
Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues
-
Qian F., Bajkowski A.S., Steiner D.F., Chan S.J., and Frankfater A. Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues. Cancer Res. 49 (1989) 4870-4875
-
(1989)
Cancer Res.
, vol.49
, pp. 4870-4875
-
-
Qian, F.1
Bajkowski, A.S.2
Steiner, D.F.3
Chan, S.J.4
Frankfater, A.5
-
38
-
-
0026575258
-
Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues
-
Buck M.R., Karustis D.G., Day N.A., Honn K.V., and Sloane B.F. Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues. Biochem. J. 282 Pt. 1 (1992) 273-278
-
(1992)
Biochem. J.
, vol.282
, Issue.PART 1
, pp. 273-278
-
-
Buck, M.R.1
Karustis, D.G.2
Day, N.A.3
Honn, K.V.4
Sloane, B.F.5
-
39
-
-
33746255613
-
Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice
-
Sevenich L., Pennacchio L.A., Peters C., and Reinheckel T. Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice. Biol. Chem. 387 (2006) 885-891
-
(2006)
Biol. Chem.
, vol.387
, pp. 885-891
-
-
Sevenich, L.1
Pennacchio, L.A.2
Peters, C.3
Reinheckel, T.4
-
40
-
-
1542513776
-
Identification of p53 regulators by genome-wide functional analysis
-
Huang Q., Raya A., DeJesus P., Chao S.-H., Quon K.C., Caldwell J.S., Chanda S.K., Izpisua-Belmonte J.C., and Schultz P.G. Identification of p53 regulators by genome-wide functional analysis. Proc. Natl. Acad. Sci. USA 101 (2004) 3456-3461
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3456-3461
-
-
Huang, Q.1
Raya, A.2
DeJesus, P.3
Chao, S.-H.4
Quon, K.C.5
Caldwell, J.S.6
Chanda, S.K.7
Izpisua-Belmonte, J.C.8
Schultz, P.G.9
-
41
-
-
27144540980
-
Characterisation of a novel p53 down-regulated promoter in intron 3 of the human MDM2 oncogene
-
Liang H., and Lunec J. Characterisation of a novel p53 down-regulated promoter in intron 3 of the human MDM2 oncogene. Gene 361 (2005) 112-118
-
(2005)
Gene
, vol.361
, pp. 112-118
-
-
Liang, H.1
Lunec, J.2
-
42
-
-
0346729917
-
Multiple response elements and differential p53 binding control Perp expression during apoptosis
-
Reczek E.E., Flores E.R., Tsay A.S., Attardi L.D., and Jacks T. Multiple response elements and differential p53 binding control Perp expression during apoptosis. Mol. Cancer Res. 1 (2003) 1048-1057
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 1048-1057
-
-
Reczek, E.E.1
Flores, E.R.2
Tsay, A.S.3
Attardi, L.D.4
Jacks, T.5
|