Effect of vaginal distention on elastic fiber synthesis and matrix degradation in the vaginal wall: Potential role in the pathogenesis of pelvic organ prolapse

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 295, Issue 4, 2008, Pages

  Rahn, D D ^a   Acevedo, J F ^a   Word, R A ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Childbirth trauma; MMP9; Pregnancy; Protease

Indexed keywords

FIBULIN 5; GELATINASE A; GELATINASE B; TROPOELASTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELASTIC FIBER; ENZYME ACTIVITY; FEMALE; HOMEOSTASIS; MOUSE; NONHUMAN; PATHOGENESIS; PELVIC ORGAN PROLAPSE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; VAGINAL DELIVERY;

ANIMALS; BALLOON DILATATION; BIOMECHANICS; ELASTIC TISSUE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME PRECURSORS; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GELATINASES; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; PELVIC FLOOR; PERINEUM; PREGNANCY; PREGNANCY COMPLICATIONS; RECOMBINANT PROTEINS; TROPOELASTIN; UTERINE PROLAPSE; VAGINA;

EID: 57349119031     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.90447.2008     Document Type: Article

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