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Volumn 93, Issue 12, 2008, Pages 1890-1893

The allele burden of JAK2 mutations remains stable over several years in patients with myeloproliferative disorders

Author keywords

Hydroxyurea; Interferon; JAK2 V617F; Janus kinase

Indexed keywords

ALPHA2A INTERFERON; ANAGRELIDE; DNA; HYDROXYUREA; JANUS KINASE 2;

EID: 57349118016     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: 10.3324/haematol.13074     Document Type: Article
Times cited : (35)

References (28)
  • 1
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, Staerk J, Delhommeau F, Lacout C, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-8.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3    Staerk, J.4    Delhommeau, F.5    Lacout, C.6
  • 2
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005;365:1054-61.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3    East, C.4    Fourouclas, N.5    Swanton, S.6
  • 3
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005;7:387-97.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3    Ebert, B.L.4    Wernig, G.5    Huntly, B.J.6
  • 6
    • 33748684367 scopus 로고    scopus 로고
    • The JAK2-V617F mutation is frequently present at diagnosis in patients with essential thrombocythemia and polycythemia vera
    • Lippert E, Boissinot M, Kralovics R, Girodon F, Dobo I, Praloran V, et al. The JAK2-V617F mutation is frequently present at diagnosis in patients with essential thrombocythemia and polycythemia vera. Blood 2006;108:1865-7.
    • (2006) Blood , vol.108 , pp. 1865-1867
    • Lippert, E.1    Boissinot, M.2    Kralovics, R.3    Girodon, F.4    Dobo, I.5    Praloran, V.6
  • 8
    • 43549105688 scopus 로고    scopus 로고
    • Clonal heterogeneity in polycythemia vera patients with JAK2 exon12 and JAK2-V617F mutations
    • Li S, Kralovics R, De Libero G, Theocharides A, Gisslinger H, Skoda RC. Clonal heterogeneity in polycythemia vera patients with JAK2 exon12 and JAK2-V617F mutations. Blood 2008;111:3863-6.
    • (2008) Blood , vol.111 , pp. 3863-3866
    • Li, S.1    Kralovics, R.2    De Libero, G.3    Theocharides, A.4    Gisslinger, H.5    Skoda, R.C.6
  • 9
    • 28244442441 scopus 로고    scopus 로고
    • Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: A prospective study
    • Campbell PJ, Scott LM, Buck G, Wheatley K, East CL, Marsden JT, et al. Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study. Lancet 2005;366:1945-53.
    • (2005) Lancet , vol.366 , pp. 1945-1953
    • Campbell, P.J.1    Scott, L.M.2    Buck, G.3    Wheatley, K.4    East, C.L.5    Marsden, J.T.6
  • 10
    • 42949094077 scopus 로고    scopus 로고
    • The presence of JAK2V617F in primary myelofibrosis or its allele burden in polycythemia vera predicts chemosensitivity to hydroxyurea
    • Sirhan S, Lasho TL, Hanson CA, Mesa RA, Pardanani A, Tefferi A. The presence of JAK2V617F in primary myelofibrosis or its allele burden in polycythemia vera predicts chemosensitivity to hydroxyurea. Am J Hematol 2008;83:363-5.
    • (2008) Am J Hematol , vol.83 , pp. 363-365
    • Sirhan, S.1    Lasho, T.L.2    Hanson, C.A.3    Mesa, R.A.4    Pardanani, A.5    Tefferi, A.6
  • 11
    • 33746059048 scopus 로고    scopus 로고
    • High molecular response rate of polycythemia vera patients treated with pegylated interferon alpha-2a
    • Kiladjian JJ, Cassinat B, Turlure P, Cambier N, Roussel M, Bellucci S, et al. High molecular response rate of polycythemia vera patients treated with pegylated interferon alpha-2a. Blood 2006;108:2037-40.
    • (2006) Blood , vol.108 , pp. 2037-2040
    • Kiladjian, J.J.1    Cassinat, B.2    Turlure, P.3    Cambier, N.4    Roussel, M.5    Bellucci, S.6
  • 12
    • 33645740979 scopus 로고    scopus 로고
    • Minimal molecular response in polycythemia vera patients treated with imatinib or interferon alpha
    • Jones AV, Silver RT, Waghorn K, Curtis C, Kreil S, Zoi K, et al. Minimal molecular response in polycythemia vera patients treated with imatinib or interferon alpha. Blood 2006;107:3339-41.
    • (2006) Blood , vol.107 , pp. 3339-3341
    • Jones, A.V.1    Silver, R.T.2    Waghorn, K.3    Curtis, C.4    Kreil, S.5    Zoi, K.6
  • 13
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasms
    • Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood 2002;100:2292-302.
    • (2002) Blood , vol.100 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 14
    • 0032901326 scopus 로고    scopus 로고
    • Diagnostic criteria and prognosis in polycythemia vera and essential thrombocythemia
    • Murphy S. Diagnostic criteria and prognosis in polycythemia vera and essential thrombocythemia. Semin Hematol 1999;36(1 Suppl 2):9-13.
    • (1999) Semin Hematol , vol.36 , Issue.1 SUPPL. 2 , pp. 9-13
    • Murphy, S.1
  • 15
    • 0035108768 scopus 로고    scopus 로고
    • Evaluation of diagnostic criteria in polycythemia vera
    • Pearson TC. Evaluation of diagnostic criteria in polycythemia vera. Semin Hematol 2001;38(1 Suppl 2):21-4.
    • (2001) Semin Hematol , vol.38 , Issue.1 SUPPL. 2 , pp. 21-24
    • Pearson, T.C.1
  • 16
    • 33747199312 scopus 로고    scopus 로고
    • Acquisition of the V617F mutation of JAK2 is a late genetic event in a subset of patients with myeloproliferative disorders
    • Kralovics R, Teo SS, Li S, Theocharides A, Buser AS, Tichelli A, et al. Acquisition of the V617F mutation of JAK2 is a late genetic event in a subset of patients with myeloproliferative disorders. Blood 2006;108:1377-80.
    • (2006) Blood , vol.108 , pp. 1377-1380
    • Kralovics, R.1    Teo, S.S.2    Li, S.3    Theocharides, A.4    Buser, A.S.5    Tichelli, A.6
  • 18
    • 33846880278 scopus 로고    scopus 로고
    • Monitoring of the JAK2-V617F mutation by highly sensitive quantitative real-time PCR after allogeneic stem cell transplantation in patients with myelofibrosis
    • Kroger N, Badbaran A, Holler E, Hahn J, Kobbe G, Bornhauser M, et al. Monitoring of the JAK2-V617F mutation by highly sensitive quantitative real-time PCR after allogeneic stem cell transplantation in patients with myelofibrosis. Blood 2007;109:1316-21.
    • (2007) Blood , vol.109 , pp. 1316-1321
    • Kroger, N.1    Badbaran, A.2    Holler, E.3    Hahn, J.4    Kobbe, G.5    Bornhauser, M.6
  • 19
    • 34250624828 scopus 로고    scopus 로고
    • Use of the activating gene mutation of the tyrosine kinase (VAL617Phe) JAK2 as a minimal residual disease marker in patients with myelofibrosis and myeloid metaplasia after allogeneic stem cell transplantation
    • Steckel NK, Koldehoff M, Ditschkowski M, Beelen DW, Elmaagacli AH. Use of the activating gene mutation of the tyrosine kinase (VAL617Phe) JAK2 as a minimal residual disease marker in patients with myelofibrosis and myeloid metaplasia after allogeneic stem cell transplantation. Transplantation 2007; 83:1518-20.
    • (2007) Transplantation , vol.83 , pp. 1518-1520
    • Steckel, N.K.1    Koldehoff, M.2    Ditschkowski, M.3    Beelen, D.W.4    Elmaagacli, A.H.5
  • 20
    • 25844447519 scopus 로고    scopus 로고
    • JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia
    • Jelinek J, Oki Y, Gharibyan V, Bueso-Ramos C, Prchal JT, Verstovsek S, et al. JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia. Blood 2005;106:3370-3.
    • (2005) Blood , vol.106 , pp. 3370-3373
    • Jelinek, J.1    Oki, Y.2    Gharibyan, V.3    Bueso-Ramos, C.4    Prchal, J.T.5    Verstovsek, S.6
  • 21
    • 33749434271 scopus 로고    scopus 로고
    • Mutation of JAK2 in the myeloproliferative disorders: Timing, clonality studies, cytogenetic associations, and role in leukemic transformation
    • Campbell PJ, Baxter EJ, Beer PA, Scott LM, Bench AJ, Huntly BJ, et al. Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation. Blood 2006;108:3548-55.
    • (2006) Blood , vol.108 , pp. 3548-3555
    • Campbell, P.J.1    Baxter, E.J.2    Beer, P.A.3    Scott, L.M.4    Bench, A.J.5    Huntly, B.J.6
  • 22
    • 34347394712 scopus 로고    scopus 로고
    • Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation
    • Theocharides A, Boissinot M, Girodon F, Garand R, Teo SS, Lippert E, et al. Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation. Blood 2007;110:375-9.
    • (2007) Blood , vol.110 , pp. 375-379
    • Theocharides, A.1    Boissinot, M.2    Girodon, F.3    Garand, R.4    Teo, S.S.5    Lippert, E.6
  • 23
    • 43749106920 scopus 로고    scopus 로고
    • NPM1-mutated acute myeloid leukaemia occurring in JAK2-V617F+ primary myelofibrosis: Denovo origin?
    • Pasqualucci L, Li S, Meloni G, Schnittger S, Gattenlohner S, Liso A, et al. NPM1-mutated acute myeloid leukaemia occurring in JAK2-V617F+ primary myelofibrosis: denovo origin? Leukemia 2008;22:1459-63.
    • (2008) Leukemia , vol.22 , pp. 1459-1463
    • Pasqualucci, L.1    Li, S.2    Meloni, G.3    Schnittger, S.4    Gattenlohner, S.5    Liso, A.6
  • 24
    • 33846007215 scopus 로고    scopus 로고
    • Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis
    • Delhommeau F, Dupont S, Tonetti C, Masse A, Godin I, Le Couedic JP, et al. Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis. Blood 2007;109:71-7.
    • (2007) Blood , vol.109 , pp. 71-77
    • Delhommeau, F.1    Dupont, S.2    Tonetti, C.3    Masse, A.4    Godin, I.5    Le Couedic, J.P.6
  • 25
    • 33750611344 scopus 로고    scopus 로고
    • Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera
    • Ishii T, Bruno E, Hoffman R, Xu M. Involvement of various hematopoietic-cell lineages by the JAK2V617F mutation in polycythemia vera. Blood 2006;108:3128-34.
    • (2006) Blood , vol.108 , pp. 3128-3134
    • Ishii, T.1    Bruno, E.2    Hoffman, R.3    Xu, M.4
  • 26
    • 48749127301 scopus 로고    scopus 로고
    • Rapid decline of JAK2V617F levels during hydroxyurea treatment in patients with polycythemia vera and essential thrombocythemia
    • Ricksten A, Palmqvist L, Johansson P, Andreasson B. Rapid decline of JAK2V617F levels during hydroxyurea treatment in patients with polycythemia vera and essential thrombocythemia. Haematologica 2008;93:1260-1.
    • (2008) Haematologica , vol.93 , pp. 1260-1261
    • Ricksten, A.1    Palmqvist, L.2    Johansson, P.3    Andreasson, B.4
  • 27
    • 34547953018 scopus 로고    scopus 로고
    • Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera or essential thrombocythemia
    • Vannucchi AM, Antonioli E, Guglielmelli P, Rambaldi A, Barosi G, Marchioli R, et al. Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera or essential thrombocythemia. Blood 2007;110:840-6.
    • (2007) Blood , vol.110 , pp. 840-846
    • Vannucchi, A.M.1    Antonioli, E.2    Guglielmelli, P.3    Rambaldi, A.4    Barosi, G.5    Marchioli, R.6


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