Treatment with the specific estrogen receptor antagonist ICI 182,780 demasculinizes neuron soma size in the developing zebra finch brain

Brain Research

Volumn 1246, Issue , 2008, Pages 47-53

  Bender, Andrea T ^a   Veney, Sean L ^a  

^a KENT STATE UNIVERSITY   (United States)

Author keywords

Estrogens; Intracranial injection; Neural song circuit; Sexual differentiation; Songbird; Steroid hormone antagonist

Indexed keywords

ESTROGEN; FULVESTRANT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIRD; BRAIN DEVELOPMENT; BRAIN NUCLEUS; CELL SIZE; CONTROLLED STUDY; FEMALE; HATCHING; HIGH VOCAL CENTER; HISTOPATHOLOGY; MAGNOCELLULAR NUCLEUS; MALE; NERVE CELL; NONHUMAN; POEPHILA CASTANOTIS; PRIORITY JOURNAL; ROBUST NUCLEUS OF THE ARCHOPALLIUM; SEX DIFFERENCE;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; ESTRADIOL; ESTROGEN ANTAGONISTS; FEMALE; FINCHES; MALE; MODELS, ANIMAL; NEURONS; RANDOM ALLOCATION; SEX CHARACTERISTICS; VOCALIZATION, ANIMAL;

ANIMALIA; PASSERI; TAENIOPYGIA GUTTATA;

EID: 57249103354     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.09.089     Document Type: Article

References (59)

1. Adkins-Regan E., and Ascenzi M. Sexual differentiation of behavior in the zebra finch: effect of early gonadectomy or androgen treatment. Horm. Behav. 24 (1990) 114-127
2. Adkins-Regan E., Mansukhani V., Seiwert C., and Thompson R. Sexual differentiation of brain and behavior in the zebra finch: critical periods for effects of early estrogen treatment. J. Neurobiol. 25 (1994) 865-877
3. Alfinito P.D., Xiaohong C., Atherton J., Cosmi S., and Deecher D.C. ICI 182,780 penetrates brain and hypothalamic tissue and has functional effects in the brain after systemic dosing. Endocrinology 149 (2008) 5219-5226
4. Anderson W.A., Kang Y., and DeSombre E. Estrogen and antagonist-induced changes in endometrial topography of immature and cycling rats. J. Cell Biol. 64 (1975) 692-703
5. Anderson W.A., Kang Y., and DeSombre E. Endogenous peroxidase: specific marker enzyme for tissues displaying growth dependency on estrogen. J. Cell Biol. 64 (1975) 668-681
6. Arnold A.P. Effects of androgens on volumes of sexually dimorphic brain regions in the zebra finch. Brain Res. 185 (1980) 441-444
7. Balthazart J., Absil P., Fiasse V., and Ball G.F. Effects of the aromatase inhibitor R76713 on sexual differentiation of brain and behavior in zebra finches. Behaviour 131 (1994) 225-259
8. Beato M. Gene regulation by steroid hormones. Cell 56 (1989) 335-344
9. Bernard D.J., Bentley G.E., Balthazart J., Turek F.W., and Ball G.F. Androgen receptor, estrogen receptor α, and estrogen receptor β show distinct patterns of expression in forebrain song control nuclei of European starlings. Endocrinology 140 (1999) 4633-4643
10. Berry M., Metzger D., and Chambon P. Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-complex dependent agonistic activity of the antioestrogen 4-hydroxytamoxifen. Eur. Mol. Biol. Organ. J. 9 (1990) 2811-2818
11. Bottjer S.W., and Hewer S.J. Castration and antisteroid treatment impair vocal learning in male zebra finches. J. Neurobiol. 23 (1992) 337-353
12. Bottjer S.W., Miesner E.A., and Arnold A.P. Forebrain lesions disrupt development but not maintenance of song in passerine birds. Science 224 (1984) 901-903
13. Dauvois S., White R., and Parker M.G. The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling. J. Cell Sci. 106 (1993) 1377-1388
14. Dayan G., Lupien M., Auger A., Anghel S.I., Rocha W., Croisetiere S., Katzenellenbogen J.A., and Mader S. Tamoxifen and raloxifene differ in their functional interactions with aspartate 351 of estrogen receptor α. Mol. Pharmacol. 70 (2006) 579-588
15. Feder H. Perinatal hormones and their role in the development of sexually dimorphic behaviors. In: Adler N.T. (Ed). Neuroendocrinology of Reproduction (1981), Plenum Press, New York, NY 127-157
16. Gahr M., and Konishi M. Developmental changes in estrogen-sensitive neurons in the forebrain of the zebra finch. Proc. Natl. Acad. Sci. 85 (1988) 7380-7383
17. Grisham W., Mathews G.A., and Arnold A.P. Local intracerebral implants of estrogen masculinize some aspects of the zebra finch song system. J. Neurobiol. 25 (1994) 185-196
18. Gurney M.E. Hormonal control of cell form and number in the zebra finch song system. J. Neurosci. 1 (1981) 658-673
19. Gurney M.E. Behavioral correlates of sexual differentiation in the zebra finch song system. Brain Res. 231 (1982) 153-172
20. Gurney M.E., and Konishi M. Hormone-induced sexual differentiation of brain and behavior in zebra finches. Science 208 (1980) 1380-1383
21. Henry E.C., and Miller R.K. The antiestrogen LY117018 is estrogenic in the fetal rat. Teratology 34 (1986) 59-63
22. Holloway C.C., and Clayton D.F. Estrogen synthesis in the male brain triggers development of the avian song control pathway in vitro. Nat. Neurosci. 4 (2001) 170-175
23. Howell A., Kent-Osborne C., Morris C., and Wakeling A. ICI 182,780 (faslodex): development of a novel, "pure" antiestrogen. Cancer 89 (2000) 817-825
24. Hutchison J.B., Wingfield J.C., and Hutchinson R.E. Sex differences in plasma concentrations of steroids during the sensitive period for brain differentiation in the zebra finch. J. Endocrinol. 103 (1984) 363-369
25. Jacobs E.C., Arnold A.P., and Campagnoni A.T. Developmental regulation of the distribution of aromatase- and estrogen-receptor-mRNA-expressing cells in the zebra finch brain. Dev. Neurosci. 21 (1999) 453-472
26. Jacobs E.C., Grisham W., and Arnold A.P. Lack of a synergistic effect between estradiol and dihydrotestosterone in the masculinization of the zebra finch song system. J. Neurobiol. 27 (1995) 513-519
27. Jordan V.C., and Gosden B. Importance of the alkylaminoethoxy side-chain for the estrogenic and antiestrogenic actions of tamoxifen and trioxifene in the immature rat fetus. Mol. Cell. Endocrinol. 27 (1982) 291-306
28. Konishi M., and Akutagawa E. Neuronal growth, atrophy and death in a sexually dimorphic song nucleus in the zebra finch brain. Nature 315 (1985) 145-147
29. Lundeen S.G., Carver J.M., McKean M.L., and Winneker R.C. Characterization of the ovariectomized rat model for the evaluation of estrogen effects on plasma cholesterol levels. Endocrinology 138 (1997) 1552-1558
30. MacGregor J.I., and Jordan V.C. Basic guide to the mechanisms of antiestrogen action. Pharmacol. Rev. 50 (1998) 151-196
31. Martin L.C., and Veney S.L. The specific estrogen receptor antagonist ICI 182,780 masculinizes development of the zebra finch syrinx. Gen. and Comp. Endocrinol. 156 (2008) 434-439
32. Mathews G.A. Tamoxifen's effects on the zebra finch song system are estrogenic, not antiestrogenic. J. Neurobiol. 22 (1991) 957-969
33. Mathews G.A., and Arnold A.P. Antiestrogens fail to prevent the masculine ontogeny of the zebra finch song system. Gen. Comp. Endocrinol. 80 (1990) 48-58
34. Mathews G.A., Brenowitz E.A., and Arnold A.P. Paradoxical hypermasculinization of the zebra finch song system by an antiestrogen. Horm. Behav. 22 (1988) 540-551
35. McMurray R., Islamov R., and Murashov A.K. Raloxifene analog LY117018 enhances the regeneration of sciatic nerve in ovariectomized female mice. Brain Res. 980 (2003) 140-145
36. Naftolin F., and MacLusky N. Aromatization hypothesis revisited. In: Serio M. (Ed). Sexual Differentiation: Basic and Clinical Aspects (1984), Raven Press, New York, NY 79-91
37. Nordeen E.J., and Nordeen K.W. Estrogen stimulates the incorporation of new neurons into avian song nuclei during adolescence. Brain Res. 49 (1989) 27-32
38. Nordeen K.W., Nordeen E.J., and Arnold A.P. Estrogen accumulation in zebra finch song control nuclei: implications for sexual differentiation and adult activation of song behavior. J. Neurobiol. 18 (1987) 569-582
39. Nottebohm F., and Arnold A.P. Sexual dimorphism in vocal control areas of the songbird brain. Science 194 (1976) 211-213
40. Nottebohm F., Stokes T.M., and Leonard C.M. Central control of song in the canary, Serinus canarius. J. Comp. Neurol. 165 (1976) 457-486
41. Perlman W.R., and Arnold A.P. Expression of estrogen receptor and aromatase mRNAs in embryonic and posthatch zebra finch brain. J. Neurobiol. 55 (2003) 2003
42. Saldanha C.J., Tuerk M.J., Kim Y.-H., Fernandes A.O., Arnold A.P., and Schlinger B.A. Distribution and regulation of telencephalic aromatase expression in the zebra finch revealed with a specific antibody. J. Comp. Neurol. 423 (2000) 619-630
43. Scharff C., and Nottebohm F. A comparative study of the behavioral deficits following lesions of various parts of the zebra finch song system: implications for vocal learning. J. Neurosci. 11 (1991) 2896-2913
44. Schlinger B.A., and Arnold A.P. Plasma sex steroid and tissue aromatization in hatchling zebra finches: implications for the sexual differentiation of singing behavior. Endocrinology 130 (1992) 289-299
45. Simpson H.B. Early estrogen treatment alone causes female zebra finches to produce learned, male-like vocalizations. J. Neurobiol. 22 (1991) 755-776
46. Simpson H.B., and Vicario D.S. Brain pathways for learned and unlearned vocalizations differ in zebra finches. J. Neurosci. 10 (1990) 1541-1556
47. Steyn F.J., Anderson G.M., and Grattan D.R. Differential effects of centrally administered oestrogen antagonist ICI 182,780 on oestrogen-sensitive functions in the hypothalamus. J. Neuroendo. 19 (2006) 26-33
48. Sun J., Huang Y.R., Harrington W.R., Sheng S., Katzenellenbogen J.A., and Katzenellenbogen B.S. ICI 182,780 penetrates brain and hypothalamic tissue and has functional effects in the brain after systemic dosing. Endocrinology 149 (2008) 5219-5226
49. Tolon R.M., Castillo A.I., Jimenez-Lara A.M., and Aranda A. Association with Ets-1 causes ligand- and AF-2 independent activation of nuclear receptors. Mol. Cell Biol. 20 (2000) 8793-8802
50. Tzukerman M.T., Esty A., Santiso-Mere D., Danielian P., Parker M.G., Stein R.B., Pike J.W., and McDonnell D.P. Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. Mol. Endocrinol. 8 (1994) 21-30
51. Van Den Bemd G.J.C.M., Kuiper G.G.J.M., Pois H.A.P., and Van Leeuwen J.P.T.M. Distinct effects on the conformation of estrogen receptor alpha and beta by both the antiestrogens ICI 164,384 and ICI 182,780 leading to opposite effects on receptor stability. Biochem. Biophys Res. Commun. 261 (1999) 1-5
52. Vockel A., Prove E., and Balthazart J. Sex- and age-related differences in the activity of testosterone-metabolizing enzymes in microdissected nuclei of the zebra finch brain. Brain Res. 511 (1990) 291-302
53. Wade G.N., Blaustein J.D., Gray J.M., and Merideth J.M. ICI 182,780: a pure antiestrogen that affects behaviors and energy balance in rats without acting in the brain. Amer. J. Phys. 265 (1993) 1392-1398
54. Wade J. Zebra finch sexual differentiation: the aromatization hypothesis revisited. Microsc. Res. Tech. 54 (2001) 354-363
55. Wade J., and Arnold A.P. Sexual Differentiation of the Zebra Finch Song System. In: Ziegler H.P., and Marler P. (Eds). Behavioral Neuroendocrinology of Birdsong (2004), Annals of the New York Academy of Sciences, New York, NY 540-559
56. Wade J., and Arnold A.P. Post-hatching inhibition of aromatase activity does not alter sexual differentiation of the zebra finch song system. Brain Res. 639 (1994) 347-350
57. Wade J., Schlinger B.A., and Arnold A.P. Aromatase and 5-β reductase activity in cultures of developing zebra finch brain: an investigation of sex and regional differences. J. Neurobiol. 27 (1995) 240-251
58. Wakeling A.E., Dukes M., and Bowler J. A potent specific pure antiestrogen with clinical potential. Cancer Res. 51 (1991) 3867-3873
59. Wijayaratne A.L., Nagel S.C., Paige L.A., Christensen D.J., Norris J.D., Fowlkes D.M., and McDonnell D.P. Comparative analysis of mechanistic differences among antiestrogens. Endocrinology 140 (1999) 5828-5840