Estrogen synthesis in the male brain triggers development of the avian song control pathway in vitro

Nature Neuroscience

Volumn 4, Issue 2, 2001, Pages 170-175

  Holloway, Carl Clayton ^a   Clayton, David F ^b  

^a Strategic Analysis   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; ESTROGEN; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN SLICE; CONTROLLED STUDY; ESTROGEN SYNTHESIS; FEMALE; GONAD; MALE; NERVE TRACT; NONHUMAN; PRIORITY JOURNAL; SEX DIFFERENCE; SEX DIFFERENTIATION; SONGBIRD; SYNAPSE; TELENCEPHALON;

ANIMALS; BRAIN; CULTURE MEDIA; ESTROGEN RECEPTOR MODULATORS; ESTROGENS; FEMALE; MALE; NEURAL PATHWAYS; SONGBIRDS; SYNAPSES; TAMOXIFEN; TELENCEPHALON; VIRILISM; VOCALIZATION, ANIMAL;

EID: 0035140595     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/84001     Document Type: Article

References (46)

1. Sexual differentiation of the vertebrate brain: Principles and mechanisms
2. Sensitive periods and circuits for learned birdsong
3. Sex steroids and their actions on the birdsong system
4. An introduction to birdsong and the avian song system
5. Building a bird brain - Sculpting neural circuits for a learned behavior
6. Central control of song in the canary
7. Waiting periods versus early innervation: The development of axonal connections in the zebra finch song system
8. Neuronal growth, atrophy and death in a sexually dimorphic song nucleus in the zebra finch
9. Sexual differentiation of the zebra finch song system - Positive evidence, negative evidence, null hypotheses, and a paradigm shift
10. The sexually dimorphic expression of androgen receptors in the song nucleus hyperstriatalis ventrale pars caudale of the zebra finch develops independently of gonadal steroids
11. Sexual differentiation of androgen accumulation within the zebra finch brain through selective cell loss and addition
12. Developmental changes in estrogen-sensitive neurons in the forebrain of the zebra finch
13. Developmental regulation of the distribution of aromatase- and estrogen-receptor- mRNA-expressing cells in the zebra finch brain
14. Hormone induced sexual differentiation of brain and behavior in zebra finches
15. Early estrogen treatment of female zebra finches masculinizes the brain pathway for learned vocalizations
16. Early estrogen treatment alone causes female zebra finches to produce learned, male-like vocalizations
17. Estrogen-inducible, sex-specific expression of brain-derived neurotrophic factor mRNA in a forebrain song control nucleus of the juvenile zebra finch
18. Post-hatching inhibition of aromatase activity does not alter sexual differentiation of the zebra finch song system
19. Antiestrogens fail to prevent the masculine ontogeny of the zebra finch song system
20. Tamoxifen's effects on the zebra finch song system are estrogenic, not antiestrogenic
21. Effects of the aromatase inhibitor r76713 on sexual differentiation of brain and behavior in zebra finches
22. Behavior of male and female zebra finches treated with an estrogen synthesis inhibitor as nestlings
23. Sex steroid levels in developing and adult male and female zebra finches (Poephila guttata)
24. Plasma sex steroids and tissue aromatization in hatchling zebra finches: Implications for the sexual differentiation of singing behavior
25. Sex differences in plasma concentrations of steroids during the sensitive period for brain differentiation in the zebra finch
26. Aromatase and 5 beta-reductase activity in cultures of developing zebra finch brain: An investigation of sex and regional differences
27. Sex- and age-related differences in the activity of testosterone-metabolizing enzymes in microdissected nuclei of the zebra finch brain
28. Development of AChE-positive neuronal projections from basal forebrain to cerebral cortex in organotypic tissue slice cultures
29. The dynamics of dendritic structure in developing hippocampal slices
30. Development of signals influencing the growth and termination of thalamocortical axons in organotypic culture
31. Organotypic culture of the developing cerebral cortex and hypothalamus: Relevance to sexual differentiation
32. Characterization of the suprachiasmatic nucleus in organotypic slice explant cultures
33. A simple method for organotypic cultures of nervous tissue
34. In vitro neurogenesis by neuronal precursor cells derived from the adult songbird brain
35. Fluorescent carbocyanine dyes allow living neurons of identified origin to be studied in long-term cultures
36. Fiber outgrowth and pathfinding in the developing auditory brainstem
37. Axonal connections of the high vocal center and surrounding cortical regions in juvenile and adult male zebra finches
38. Fadrozole: A potent and specific inhibitor of aromatase in the zebra finch brain
39. Basic guide to the mechanisms of antiestrogen action
40. Functional testicular tissue does not masculinize development of the zebra finch song system
41. Novel mechanisms of estrogen action in the brain: New players in an old story
42. Aromatase in the cerebral cortex, hippocampus, and mid-brain: Ontogeny and developmental implications
43. Circulating estrogens in a male songbird originate in the brain
44. Brain is the major site of estrogen synthesis in a male songbird
45. 3-Beta-hydroxysteroid dehydrogenase/isomerase and aromatase activity in primary cultures of developing zebra finch telencephalon - Dehydroepiandrosterone as substrate for synthesis of androstenedione and estrogens
46. Neuronal and non-neuronal aromatase in primary cultures of developing zebra finch telencephalon