Expression levels of FAS are regulated through an evolutionary conserved element in intron 2, which modulates cystic fibrosis disease severity

Genes and Immunity

Volumn 9, Issue 8, 2008, Pages 689-696

  Kumar, V ^a   Becker, T ^b   Jansen, S ^a   van Barneveld, A ^a   Boztug, K ^a   Wolfl S ^c   Tummler B ^a   Stanke, F ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; TRANSCRIPTION FACTOR REL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; BINDING SITE; CASE CONTROL STUDY; CONTROLLED STUDY; CYSTIC FIBROSIS; DISEASE SEVERITY; EUROPE; GENE EXPRESSION REGULATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; HAPLOTYPE; HOMOZYGOSITY; HUMAN; INTESTINE EPITHELIUM; INTRON; MOLECULAR PHYLOGENY; NUCLEAR FAMILY; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SIBLING; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; ANTIGENS, CD95; BASE SEQUENCE; COHORT STUDIES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EVOLUTION, MOLECULAR; FEMALE; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; INTRONS; MALE; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ALIGNMENT; SIBLINGS;

EID: 57249094345     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2008.63     Document Type: Article

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