Basic control of reperfusion effectively protects against reperfusion injury in a realistic rodent model of acute limb ischemia

Circulation

Volumn 118, Issue 19, 2008, Pages 1920-1928

  Dick, Florian ^a,b   Li, Jianhui ^a,c   Giraud, Marie Noëlle ^a   Kalka, Christoph ^a   Schmidli, Juerg ^a   Tevaearai, Hendrik ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b CHARING CROSS HOSPITAL   (United Kingdom)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Inflammation; Ischemia; Peripheral vascular disease; Prevention; Reperfusion

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD FLOW VELOCITY; CIRCULATION; CONTROLLED STUDY; EDEMA; FEMALE; HEART MUSCLE CONTRACTILE FORCE; HEART PROTECTION; LASER DOPPLER FLOWMETRY; LIMB ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; RODENT; VENOUS STASIS;

ACUTE DISEASE; ANIMALS; ANTICOAGULANTS; DISEASE MODELS, ANIMAL; EDEMA; FEMALE; FEMORAL ARTERY; HEPARIN; HINDLIMB; LASER-DOPPLER FLOWMETRY; MALE; MUSCLE CONTRACTION; PERIPHERAL VASCULAR DISEASES; POSTTHROMBOTIC SYNDROME; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; REPERFUSION INJURY; TOURNIQUETS;

EID: 57149139824     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.108.787754     Document Type: Article

References (42)

1. Earnshaw JJ. Demography and etiology of acute leg ischemia. Semin Vasc Surg. 2001;14:86-92.
2. Singh S, Evans L, Datta D, Gaines P, Beard JD. The costs of managing lower limb-threatening ischaemia. Eur J Vasc Endovasc Surg. 1996;12:359-362.
3. Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG. Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). J Vasc Surg. 2007;45(suppl S):S5-S67.
4. Ljungman C, Holmberg L, Bergqvist D, Bergstrom R, Adami HO. Amputation risk and survival after embolectomy for acute arterial ischaemia: time trends in a defined Swedish population. Eur J Vasc Endovasc Surg. 1996;11:176-182.
5. Ouriel K, Veith FJ, Sasahara AA. A comparison of recombinant urokinase with vascular surgery as initial treatment for acute arterial occlusion of the legs: Thrombolysis or Peripheral Arterial Surgery (TOPAS) Investigators. N Engl J Med. 1998;338:1105-1111.
6. Jivegard L, Holm J, Schersten T. Acute limb ischemia due to arterial embolism or thrombosis: influence of limb ischemia versus pre-existing cardiac disease on postoperative mortality rate. J Cardiovasc Surg (Torino). 1988;29:32-36.
7. Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL, Hiratzka LF, Murphy WR. ACC/AHA 2005 practice guidelines for the management of patients with peripheral arterial disease. Circulation. 2006;113:e463-e654.
8. Collard CD, Gelman S. Pathophysiology, clinical manifestations, and prevention of ischemia-reperfusion injury. Anesthesiology. 2001;94:1133-1138.
9. Blaisdell FW. The pathophysiology of skeletal muscle ischemia and the reperfusion syndrome: a review. Cardiovasc Surg. 2002;10:620-630.
10. Garden DL, Granger DN. Pathophysiology of ischaemia-reperfusion injury. J Pathol. 2000;190:255-266.
11. Khalil AA, Aziz FA, Hall JC. Reperfusion injury. Plast Reconstr Surg. 2006;117:1024-1033.
12. Rezkalla SH, Kloner RA. No-reflow phenomenon. Circulation. 2002; 105:656-662.
13. Haimovici H. Proceedings: myopathic-nephrotic-metabolic syndrome associated with massive acute arterial occlusions. J Cardiovasc Surg (Torino). 1973;14:589-600.
14. Pasupathy S, Homer-Vanniasinkam S. Ischaemic preconditioning protects against ischaemia/reperfusion injury: emerging concepts. Eur J Vasc Endovasc Surg. 2005;29:106-115.
15. Cryer HG. Therapeutic approaches for clinical ischemia and reperfusion injury. Shock. 1997;8:26-32.
16. Beyersdorf F, Matheis G, Kruger S, Hanselmann A, Freisleben HG, Zimmer G, Satter P. Avoiding reperfusion injury after limb revascularization: experimental observations and recommendations for clinical application. J Vasc Surg. 1989;9:757-766.
17. Okamoto F, Allen BS, Buckberg GD, Bugyi H, Leaf J. Reperfusion conditions: importance of ensuring gentle versus sudden reperfusion during relief of coronary occlusion. J Thorac Cardiovasc Surg. 1986;92:613-620.
18. Mowlavi A, Neumeister MW, Wilhelmi BJ, Song YH, Suchy H, Russell RC. Local hypothermia during early reperfusion protects skeletal muscle from ischemia-reperfusion injury. Plast Reconstr Surg. 2003;111:242-250.
19. Wright JG, Belkin M, Hobson RW 2nd. Hypothermia and controlled reperfusion: two non-pharmacologic methods which diminish ischemia-reperfusion injury in skeletal muscle. Microcirc Endothelium Lymphatics. 1989;5:315-334.
20. Chun K, Zhang J, Biewer J, Ferguson D, Clemens MG. Microcirculatory failure determines lethal hepatocyte injury in ischemic/reperfused rat livers. Shock. 1994;1:3-9.
21. Byrne JG, Appleyard RF, Lee CC, Couper GS, Scholl FG, Laurence RG, Cohn LH. Controlled reperfusion of the regionally ischemic myocardium with leukocyte-depleted blood reduces stunning, the no-reflow phenomenon, and infarct size. J Thorac Cardiovasc Surg. 1992;103:66-71.
22. Halldorsson AO, Kronon M, Allen BS, Rahman S, Wang T, Layland M, Sidle D. Controlled reperfusion prevents pulmonary injury after 24 hours of lung preservation. Ann Thorac Surg. 1998;66:877-884.
23. Rubin BB, Romaschin A, Walker PM, Gute DC, Korthuis RJ. Mechanisms of postischemic injury in skeletal muscle: intervention strategies. J Appl Physiol. 1996;80:369-387.
24. Beyersdorf F, Mitrev Z, Ihnken K, Schmiedt W, Sarai K, Eckel L, Friesewinkel O, Matheis G, Buckberg GD. Controlled limb reperfusion in patients having cardiac operations. J Thorac Cardiovasc Surg. 1996;111:873-881.
25. Defraigne JO, Pincemail J, Laroche C, Blaffart F, Limet R. Successful controlled limb reperfusion after severe prolonged ischemia. J Vasc Surg. 1997;26:346-350.
26. Walker PM, Romaschin AD, Davis S, Piovesan J. Lower limb ischemia: phase I results of salvage perfusion. J Surg Res. 1999;84:193-198.
27. Wilhelm MP, Schlensak C. Hoh A. Knipping L, Mangold G, Rojas DD, Beyersdorf F. Controlled reperfusion using a simplified perfusion system preserves function after acute and persistent limb ischemia: a preliminary study. J Vasc Surg. 2005;42:690-694.
28. Bonheur JA, Albadawi H, Patton GM, Watkins MT. A noninvasive murine model of hind limb ischemia-reperfusion injury. J Surg Res. 2004;116:55-63.
29. Position of the American Heart Association on research animal use. Circulation. 1985;71:849A-850A.
30. Andrade FH, Hatala DA, McMullen CA. Carbonic anhydrase isoform expression and functional role in rodent extraocular muscle. Pflugers Arch. 2004;448:547-551.
31. Mellors LJ, Barclay CJ. The energetics of rat papillary muscles undergoing realistic strain patterns. J Exp Biol. 2001;204:3765-3777.
32. Buckberg GD. When is cardiac muscle damaged irreversibly? J Thorac Cardiovasc Surg. 1986;92:483-487.
33. Vogt PR, von Segesser LK, Pagotto E, Lijovic T, Turina MI. Simplified, controlled limb reperfusion and simultaneous revascularization for acute aortic occlusion. J Vasc Surg. 1996;23:730-733.
34. Walker PM. Ischemia/reperfusion injury in skeletal muscle. Ann Vasc Surg. 1991;5:399-402.
35. Beyersdorf F, Unger A, Wildhirt A, Kretrer U, Deutschlander N, Kruger S, Matheis G, Hanselmann A, Zimmer G, Satter P. Studies of reperfusion injury in skeletal muscle: preserved cellular viability after extended periods of warm ischemia. J Cardiovasc Surg (Torino). 1991;32:664-676.
36. Walker PM, Lindsay TF, Labbe R, Mickle DA, Romaschin AD. Salvage of skeletal muscle with free radical scavengers. J Vasc Surg. 1987;5:68-75.
37. Matheis G, Beyersdorf F, Hanselmann A, Unger A, Wildhirt A, Kruger S, Zimmer G, Satter P. Reperfusion injury in skeletal muscle: interaction of osmotic and colloid-osmotic pressure in the initial reperfusate for oedema prevention. Cardiovasc Surg. 1994;2:725-736.
38. Hua HT, Albadawi H, Entabi F, Conrad M, Stoner MC, Meriam BT, Sroufe R, Houser S, Lamuraglia GM, Watkins MT. Polyadenosine diphosphate-ribose polymerase inhibition modulates skeletal muscle injury following ischemia reperfusion. Arch Surg. 2005;140:344-351.
39. Crawford RS, Hashmi FF, Jones JE, Albadawi H, McCormack M, Eberlin K, Entabi F, Atkins MD, Conrad MF, Austen WG Jr, Watkins MT. A novel model of acute murine hindlimh ischemia. Am J Physiol Heart Circ Physiol. 2007;292:H830-H837.
40. Hjortdal VE, Hansen ES, Hauge E. Myocutaneous flap ischemia: flow dynamics following venous and arterial obstruction. Plast Reconstr Surg. 1992;89:1083-1091.
41. Mankoff SP, Brander C, Ferrone S, Marincola FM. Lost in translation: obstacles to translational medicine. J Transl Med. 2004;2:14.
42. Arieli D, Nahmany G, Casap N, Ad-El D, Samuni Y. The effect of a nitroxide antioxidant on ischemia-reperfusion injury in the rat in vivo hind limb model. Free Radic Res. 2008;42:114-123.