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Volumn 199, Issue 6, 2008, Pages 648.e1-648.e9

Single nucleotide polymorphisms in the progesterone receptor gene and association with uterine leiomyoma tumor characteristics and disease risk

Author keywords

fibroid; leiomyoma; progesterone receptor; single nucleotide polymorphisms

Indexed keywords

PROGESTERONE RECEPTOR; STEROID HORMONE; STEROID RECEPTOR;

EID: 57149132678     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2008.06.015     Document Type: Article
Times cited : (15)

References (68)
  • 1
    • 0025061721 scopus 로고
    • The frequency of uterine leiomyomas
    • Cramer S.F., and Patel A. The frequency of uterine leiomyomas. Am J Clin Pathol 94 (1990) 435-438
    • (1990) Am J Clin Pathol , vol.94 , pp. 435-438
    • Cramer, S.F.1    Patel, A.2
  • 4
    • 0035029723 scopus 로고    scopus 로고
    • Epidemiology of uterine leiomyomata
    • Schwartz S.M. Epidemiology of uterine leiomyomata. Clin Obstet Gynecol 44 (2001) 316-326
    • (2001) Clin Obstet Gynecol , vol.44 , pp. 316-326
    • Schwartz, S.M.1
  • 5
    • 0029156107 scopus 로고
    • Epidemiology of uterine leiomyomas. With an etiologic hypothesis
    • Cramer S.F., Horiszny J.A., and Leppert P. Epidemiology of uterine leiomyomas. With an etiologic hypothesis. J Reprod Med 40 (1995) 595-600
    • (1995) J Reprod Med , vol.40 , pp. 595-600
    • Cramer, S.F.1    Horiszny, J.A.2    Leppert, P.3
  • 6
    • 0033675058 scopus 로고    scopus 로고
    • Pathology and pathophysiology of uterine smooth-muscle tumors
    • Robboy S.J., Bentley R.C., Butnor K., and Anderson M.C. Pathology and pathophysiology of uterine smooth-muscle tumors. Environ Health Perspect 108 Suppl 5 (2000) 779-784
    • (2000) Environ Health Perspect , vol.108 , Issue.SUPPL. 5 , pp. 779-784
    • Robboy, S.J.1    Bentley, R.C.2    Butnor, K.3    Anderson, M.C.4
  • 9
    • 20444389034 scopus 로고    scopus 로고
    • Uterine fibroids: the elephant in the room
    • Walker C.L., and Stewart E.A. Uterine fibroids: the elephant in the room. Science 308 (2005) 1589-1592
    • (2005) Science , vol.308 , pp. 1589-1592
    • Walker, C.L.1    Stewart, E.A.2
  • 10
    • 0141843833 scopus 로고
    • Leiomyosarcoma in situ of the uterus
    • Przybora L.A. Leiomyosarcoma in situ of the uterus. Cancer 14 (1961) 483-492
    • (1961) Cancer , vol.14 , pp. 483-492
    • Przybora, L.A.1
  • 11
    • 0035956680 scopus 로고    scopus 로고
    • Uterine fibroids
    • Stewart E.A. Uterine fibroids. Lancet 357 (2001) 293-298
    • (2001) Lancet , vol.357 , pp. 293-298
    • Stewart, E.A.1
  • 12
    • 0025811554 scopus 로고
    • Clustering of aberrations to specific chromosome regions in benign neoplasms
    • Sreekantaiah C., and Sandberg A.A. Clustering of aberrations to specific chromosome regions in benign neoplasms. Int J Cancer 48 (1991) 194-198
    • (1991) Int J Cancer , vol.48 , pp. 194-198
    • Sreekantaiah, C.1    Sandberg, A.A.2
  • 13
    • 0037677597 scopus 로고    scopus 로고
    • Etiology and pathogenesis of uterine leiomyomas: a review
    • Flake G.P., Andersen J., and Dixon D. Etiology and pathogenesis of uterine leiomyomas: a review. Environ Health Perspect 111 (2003) 1037-1054
    • (2003) Environ Health Perspect , vol.111 , pp. 1037-1054
    • Flake, G.P.1    Andersen, J.2    Dixon, D.3
  • 16
    • 0014949070 scopus 로고
    • Unicellular histogenesis of uterine leiomyomas as determined by electrophoresis by glucose-6-phosphate dehydrogenase
    • Townsend D.E., Sparkes R.S., Baluda M.C., and McClelland G. Unicellular histogenesis of uterine leiomyomas as determined by electrophoresis by glucose-6-phosphate dehydrogenase. Am J Obstet Gynecol 107 (1970) 1168-1173
    • (1970) Am J Obstet Gynecol , vol.107 , pp. 1168-1173
    • Townsend, D.E.1    Sparkes, R.S.2    Baluda, M.C.3    McClelland, G.4
  • 18
    • 0022961699 scopus 로고
    • Uterine leiomyomata-aetiology, symptomatology and management
    • Buttram Jr. V.C. Uterine leiomyomata-aetiology, symptomatology and management. Prog Clin Biol Res 225 (1986) 275-296
    • (1986) Prog Clin Biol Res , vol.225 , pp. 275-296
    • Buttram Jr., V.C.1
  • 19
    • 0018940352 scopus 로고
    • Myomas of the uterus in pregnancy: ultrasonographic follow-up
    • Muram D., Gillieson M., and Walters J.H. Myomas of the uterus in pregnancy: ultrasonographic follow-up. Am J Obstet Gynecol 138 (1980) 16-19
    • (1980) Am J Obstet Gynecol , vol.138 , pp. 16-19
    • Muram, D.1    Gillieson, M.2    Walters, J.H.3
  • 20
    • 0027097787 scopus 로고
    • Longitudinal evaluation of uterine myoma growth during pregnancy: a sonographic study
    • Rosati P., Exacoustos C., and Mancuso S. Longitudinal evaluation of uterine myoma growth during pregnancy: a sonographic study. J Ultrasound Med 11 (1992) 511-515
    • (1992) J Ultrasound Med , vol.11 , pp. 511-515
    • Rosati, P.1    Exacoustos, C.2    Mancuso, S.3
  • 22
    • 0000800944 scopus 로고
    • The progesterone therapy of human uterine leiomyomas
    • illust
    • Segaloff A., Weed J.C., et al. The progesterone therapy of human uterine leiomyomas. J Clin Endocrinol Metab 9 (1949) 1273-1291 illust
    • (1949) J Clin Endocrinol Metab , vol.9 , pp. 1273-1291
    • Segaloff, A.1    Weed, J.C.2
  • 23
    • 0021856674 scopus 로고
    • The effect of progestins on the mitotic activity of uterine fibromyomas
    • Tiltman A.J. The effect of progestins on the mitotic activity of uterine fibromyomas. Int J Gynecol Pathol 4 (1985) 89-96
    • (1985) Int J Gynecol Pathol , vol.4 , pp. 89-96
    • Tiltman, A.J.1
  • 24
    • 0023836712 scopus 로고
    • A randomized, double-blind trial of a gonadotropin releasing-hormone agonist (leuprolide) with or without medroxyprogesterone acetate in the treatment of leiomyomata uteri
    • Friedman A.J., Barbieri R.L., Doubilet P.M., Fine C., and Schiff I. A randomized, double-blind trial of a gonadotropin releasing-hormone agonist (leuprolide) with or without medroxyprogesterone acetate in the treatment of leiomyomata uteri. Fertil Steril 49 (1988) 404-409
    • (1988) Fertil Steril , vol.49 , pp. 404-409
    • Friedman, A.J.1    Barbieri, R.L.2    Doubilet, P.M.3    Fine, C.4    Schiff, I.5
  • 25
    • 0028064250 scopus 로고
    • Long-term medical therapy for leiomyomata uteri: a prospective, randomized study of leuprolide acetate depot plus either oestrogen-progestin or progestin 'add-back' for 2 years
    • Friedman A.J., Daly M., Juneau-Norcross M., Gleason R., Rein M.S., and LeBoff M. Long-term medical therapy for leiomyomata uteri: a prospective, randomized study of leuprolide acetate depot plus either oestrogen-progestin or progestin 'add-back' for 2 years. Hum Reprod 9 (1994) 1618-1625
    • (1994) Hum Reprod , vol.9 , pp. 1618-1625
    • Friedman, A.J.1    Daly, M.2    Juneau-Norcross, M.3    Gleason, R.4    Rein, M.S.5    LeBoff, M.6
  • 26
    • 0026759278 scopus 로고
    • Proliferative activity of human uterine leiomyoma cells as measured by automatic image analysis
    • Lamminen S., Rantala I., Helin H., Rorarius M., and Tuimala R. Proliferative activity of human uterine leiomyoma cells as measured by automatic image analysis. Gynecol Obstet Invest 34 (1992) 111-114
    • (1992) Gynecol Obstet Invest , vol.34 , pp. 111-114
    • Lamminen, S.1    Rantala, I.2    Helin, H.3    Rorarius, M.4    Tuimala, R.5
  • 28
    • 34548457702 scopus 로고    scopus 로고
    • Transcriptional analysis of steroid hormone receptors in smooth muscle uterine leiomyoma tumors of postmenopausal patients
    • Strissel P.L., Swiatek J., Oppelt P., Renner S.P., Beckmann M.W., and Strick R. Transcriptional analysis of steroid hormone receptors in smooth muscle uterine leiomyoma tumors of postmenopausal patients. J Steroid Biochem Mol Biol 107 (2007) 42-47
    • (2007) J Steroid Biochem Mol Biol , vol.107 , pp. 42-47
    • Strissel, P.L.1    Swiatek, J.2    Oppelt, P.3    Renner, S.P.4    Beckmann, M.W.5    Strick, R.6
  • 31
    • 0023491934 scopus 로고
    • Localization of the human progesterone receptor gene to chromosome 11q22-q23
    • Rousseau-Merck M.F., Misrahi M., Loosfelt H., Milgrom E., and Berger R. Localization of the human progesterone receptor gene to chromosome 11q22-q23. Hum Genet 77 (1987) 280-282
    • (1987) Hum Genet , vol.77 , pp. 280-282
    • Rousseau-Merck, M.F.1    Misrahi, M.2    Loosfelt, H.3    Milgrom, E.4    Berger, R.5
  • 32
    • 0025293539 scopus 로고
    • Progestin regulation of cellular proliferation
    • Clarke C.L., and Sutherland R.L. Progestin regulation of cellular proliferation. Endocr Rev 11 (1990) 266-301
    • (1990) Endocr Rev , vol.11 , pp. 266-301
    • Clarke, C.L.1    Sutherland, R.L.2
  • 33
    • 8544252436 scopus 로고    scopus 로고
    • Physiological action of progesterone in target tissues
    • Graham J.D., and Clarke C.L. Physiological action of progesterone in target tissues. Endocr Rev 18 (1997) 502-519
    • (1997) Endocr Rev , vol.18 , pp. 502-519
    • Graham, J.D.1    Clarke, C.L.2
  • 34
    • 0024365823 scopus 로고
    • The chicken progesterone receptor A and B isoforms are products of an alternate translation initiation event
    • Conneely O.M., Kettelberger D.M., Tsai M.J., Schrader W.T., and O'Malley B.W. The chicken progesterone receptor A and B isoforms are products of an alternate translation initiation event. J Biol Chem 264 (1989) 14062-14064
    • (1989) J Biol Chem , vol.264 , pp. 14062-14064
    • Conneely, O.M.1    Kettelberger, D.M.2    Tsai, M.J.3    Schrader, W.T.4    O'Malley, B.W.5
  • 35
    • 0023545241 scopus 로고
    • The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA
    • Conneely O.M., Maxwell B.L., Toft D.O., Schrader W.T., and O'Malley B.W. The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA. Biochem Biophys Res Commun 149 (1987) 493-501
    • (1987) Biochem Biophys Res Commun , vol.149 , pp. 493-501
    • Conneely, O.M.1    Maxwell, B.L.2    Toft, D.O.3    Schrader, W.T.4    O'Malley, B.W.5
  • 36
    • 0025239785 scopus 로고
    • Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B
    • Kastner P., Krust A., Turcotte B., Stropp U., Tora L., Gronemeyer H., et al. Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J 9 (1990) 1603-1614
    • (1990) EMBO J , vol.9 , pp. 1603-1614
    • Kastner, P.1    Krust, A.2    Turcotte, B.3    Stropp, U.4    Tora, L.5    Gronemeyer, H.6
  • 37
    • 0028073682 scopus 로고
    • A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform
    • Sartorius C.A., Melville M.Y., Hovland A.R., Tung L., Takimoto G.S., and Horwitz K.B. A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform. Mol Endocrinol 8 (1994) 1347-1360
    • (1994) Mol Endocrinol , vol.8 , pp. 1347-1360
    • Sartorius, C.A.1    Melville, M.Y.2    Hovland, A.R.3    Tung, L.4    Takimoto, G.S.5    Horwitz, K.B.6
  • 38
    • 0028033988 scopus 로고
    • The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells
    • Wen D.X., Xu Y.F., Mais D.E., Goldman M.E., and McDonnell D.P. The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells. Mol Cell Biol 14 (1994) 8356-8364
    • (1994) Mol Cell Biol , vol.14 , pp. 8356-8364
    • Wen, D.X.1    Xu, Y.F.2    Mais, D.E.3    Goldman, M.E.4    McDonnell, D.P.5
  • 39
    • 0027178707 scopus 로고
    • Progesterone receptor messenger ribonucleic acid and protein are overexpressed in human uterine leiomyomas
    • Brandon D.D., Bethea C.L., Strawn E.Y., Novy M.J., Burry K.A., Harrington M.S., et al. Progesterone receptor messenger ribonucleic acid and protein are overexpressed in human uterine leiomyomas. Am J Obstet Gynecol 169 (1993) 78-85
    • (1993) Am J Obstet Gynecol , vol.169 , pp. 78-85
    • Brandon, D.D.1    Bethea, C.L.2    Strawn, E.Y.3    Novy, M.J.4    Burry, K.A.5    Harrington, M.S.6
  • 40
    • 0030918035 scopus 로고    scopus 로고
    • Distribution of the A and B forms of the progesterone receptor messenger ribonucleic acid and protein in uterine leiomyomata and adjacent myometrium
    • Viville B., Charnock-Jones D.S., Sharkey A.M., Wetzka B., and Smith S.K. Distribution of the A and B forms of the progesterone receptor messenger ribonucleic acid and protein in uterine leiomyomata and adjacent myometrium. Hum Reprod 12 (1997) 815-822
    • (1997) Hum Reprod , vol.12 , pp. 815-822
    • Viville, B.1    Charnock-Jones, D.S.2    Sharkey, A.M.3    Wetzka, B.4    Smith, S.K.5
  • 41
    • 19944428552 scopus 로고    scopus 로고
    • Progesterone receptor promoter +331A polymorphism is associated with a reduced risk of endometrioid and clear cell ovarian cancers
    • Berchuck A., Schildkraut J.M., Wenham R.M., Calingaert B., Ali S., Henriott A., et al. Progesterone receptor promoter +331A polymorphism is associated with a reduced risk of endometrioid and clear cell ovarian cancers. Cancer Epidemiol Biomarkers Prev 13 (2004) 2141-2147
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 2141-2147
    • Berchuck, A.1    Schildkraut, J.M.2    Wenham, R.M.3    Calingaert, B.4    Ali, S.5    Henriott, A.6
  • 43
    • 0037126067 scopus 로고    scopus 로고
    • A functional polymorphism in the promoter of the progesterone receptor gene associated with endometrial cancer risk
    • De Vivo I., Huggins G.S., Hankinson S.E., Lescault P.J., Boezen M., Colditz G.A., et al. A functional polymorphism in the promoter of the progesterone receptor gene associated with endometrial cancer risk. Proc Natl Acad Sci U S A 99 (2002) 12263-12268
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 12263-12268
    • De Vivo, I.1    Huggins, G.S.2    Hankinson, S.E.3    Lescault, P.J.4    Boezen, M.5    Colditz, G.A.6
  • 44
  • 47
    • 33646414784 scopus 로고    scopus 로고
    • Two functionally relevant polymorphisms in the human progesterone receptor gene (+331 G/A and progins) and the predisposition for breast and/or ovarian cancer
    • Romano A., Lindsey P.J., Fischer D.C., Delvoux B., Paulussen A.D., Jansenn R.G., et al. Two functionally relevant polymorphisms in the human progesterone receptor gene (+331 G/A and progins) and the predisposition for breast and/or ovarian cancer. Gynecol Oncol 101 (2006) 287-295
    • (2006) Gynecol Oncol , vol.101 , pp. 287-295
    • Romano, A.1    Lindsey, P.J.2    Fischer, D.C.3    Delvoux, B.4    Paulussen, A.D.5    Jansenn, R.G.6
  • 48
    • 33845604568 scopus 로고    scopus 로고
    • Progesterone receptor polymorphism +331G/A is associated with a decreased risk of deep infiltrating endometriosis
    • van Kaam K.J., Romano A., Schouten J.P., Dunselman G.A., and Groothuis P.G. Progesterone receptor polymorphism +331G/A is associated with a decreased risk of deep infiltrating endometriosis. Hum Reprod 22 (2007) 129-135
    • (2007) Hum Reprod , vol.22 , pp. 129-135
    • van Kaam, K.J.1    Romano, A.2    Schouten, J.P.3    Dunselman, G.A.4    Groothuis, P.G.5
  • 49
    • 21644468552 scopus 로고    scopus 로고
    • The progesterone receptor Val660->Leu polymorphism and breast cancer risk
    • De Vivo I., Hankinson S.E., Colditz G.A., and Hunter D.J. The progesterone receptor Val660->Leu polymorphism and breast cancer risk. Breast Cancer Res 6 (2004) R636-R639
    • (2004) Breast Cancer Res , vol.6
    • De Vivo, I.1    Hankinson, S.E.2    Colditz, G.A.3    Hunter, D.J.4
  • 51
    • 0035026849 scopus 로고    scopus 로고
    • No significant association between progesterone receptor exon 4 Val660Leu G/T polymorphism and risk of ovarian cancer
    • Spurdle A.B., Webb P.M., Purdie D.M., Chen X., Green A., and Chenevix-Trench G. No significant association between progesterone receptor exon 4 Val660Leu G/T polymorphism and risk of ovarian cancer. Carcinogenesis 22 (2001) 717-721
    • (2001) Carcinogenesis , vol.22 , pp. 717-721
    • Spurdle, A.B.1    Webb, P.M.2    Purdie, D.M.3    Chen, X.4    Green, A.5    Chenevix-Trench, G.6
  • 53
    • 33847624062 scopus 로고    scopus 로고
    • The PROGINS polymorphism of the human progesterone receptor diminishes the response to progesterone
    • Romano A., Delvoux B., Fischer D.C., and Groothuis P. The PROGINS polymorphism of the human progesterone receptor diminishes the response to progesterone. J Mol Endocrinol 38 (2007) 331-350
    • (2007) J Mol Endocrinol , vol.38 , pp. 331-350
    • Romano, A.1    Delvoux, B.2    Fischer, D.C.3    Groothuis, P.4
  • 54
    • 34447261413 scopus 로고    scopus 로고
    • Association of progesterone receptor gene polymorphism (PROGINS) with endometriosis, uterine fibroids and breast cancer
    • Govindan S., Ahmad S.N., Vedicherla B., Kodati V., Jahan P., Rao K.P., et al. Association of progesterone receptor gene polymorphism (PROGINS) with endometriosis, uterine fibroids and breast cancer. Cancer Biomark 3 (2007) 73-78
    • (2007) Cancer Biomark , vol.3 , pp. 73-78
    • Govindan, S.1    Ahmad, S.N.2    Vedicherla, B.3    Kodati, V.4    Jahan, P.5    Rao, K.P.6
  • 56
    • 0037277601 scopus 로고    scopus 로고
    • Analysis of estrogen receptor (ERalpha and ERbeta) and progesterone receptor (PR) polymorphisms in uterine leiomyomas
    • Massart F., Becherini L., Marini F., Noci I., Piciocchi L., Del Monte F., et al. Analysis of estrogen receptor (ERalpha and ERbeta) and progesterone receptor (PR) polymorphisms in uterine leiomyomas. Med Sci Monit 9 (2003) BR25-BR30
    • (2003) Med Sci Monit , vol.9
    • Massart, F.1    Becherini, L.2    Marini, F.3    Noci, I.4    Piciocchi, L.5    Del Monte, F.6
  • 57
    • 17044380849 scopus 로고    scopus 로고
    • PROGINS Alu sequence insertion is associated with hyperprolactinaemia but not leiomyoma susceptibility
    • Hsieh Y.Y., Chan I.P., Wang H.I., Chang C.C., Huang C.W., and Lin C.S. PROGINS Alu sequence insertion is associated with hyperprolactinaemia but not leiomyoma susceptibility. Clin Endocrinol (Oxf) 62 (2005) 492-497
    • (2005) Clin Endocrinol (Oxf) , vol.62 , pp. 492-497
    • Hsieh, Y.Y.1    Chan, I.P.2    Wang, H.I.3    Chang, C.C.4    Huang, C.W.5    Lin, C.S.6
  • 58
    • 34247497261 scopus 로고    scopus 로고
    • The progesterone receptor gene polymorphism, PROGINS, may be a factor related to the development of uterine fibroids
    • Gomes M.T., Castro Rde A., Villanova F.E., da Silva I.D., Baracat E.C., de Lima G.R., et al. The progesterone receptor gene polymorphism, PROGINS, may be a factor related to the development of uterine fibroids. Fertil Steril 87 (2007) 1116-1121
    • (2007) Fertil Steril , vol.87 , pp. 1116-1121
    • Gomes, M.T.1    Castro Rde, A.2    Villanova, F.E.3    da Silva, I.D.4    Baracat, E.C.5    de Lima, G.R.6
  • 59
    • 12444331009 scopus 로고    scopus 로고
    • DNA sequence variations of the entire anti-Mullerian hormone (AMH) gene promoter and AMH protein expression in patients with the Mayer-Rokitanski-Kuster-Hauser syndrome
    • Oppelt P., Strissel P.L., Kellermann A., Seeber S., Humeny A., Beckmann M.W., et al. DNA sequence variations of the entire anti-Mullerian hormone (AMH) gene promoter and AMH protein expression in patients with the Mayer-Rokitanski-Kuster-Hauser syndrome. Hum Reprod 20 (2005) 149-157
    • (2005) Hum Reprod , vol.20 , pp. 149-157
    • Oppelt, P.1    Strissel, P.L.2    Kellermann, A.3    Seeber, S.4    Humeny, A.5    Beckmann, M.W.6
  • 60
    • 32544453015 scopus 로고    scopus 로고
    • Evaluation of clinical parameters and estrogen receptor alpha gene polymorphisms for patients with endometriosis
    • Renner S.P., Strick R., Oppelt P., Fasching P.A., Engel S., Baumann R., et al. Evaluation of clinical parameters and estrogen receptor alpha gene polymorphisms for patients with endometriosis. Reproduction 131 (2006) 153-161
    • (2006) Reproduction , vol.131 , pp. 153-161
    • Renner, S.P.1    Strick, R.2    Oppelt, P.3    Fasching, P.A.4    Engel, S.5    Baumann, R.6
  • 61
    • 0031466273 scopus 로고    scopus 로고
    • Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor
    • Giangrande P.H., Pollio G., and McDonnell D.P. Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor. J Biol Chem 272 (1997) 32889-32900
    • (1997) J Biol Chem , vol.272 , pp. 32889-32900
    • Giangrande, P.H.1    Pollio, G.2    McDonnell, D.P.3
  • 62
    • 1642332240 scopus 로고    scopus 로고
    • Estrogen signaling: a subtle balance between ER alpha and ER beta
    • Matthews J., and Gustafsson J.A. Estrogen signaling: a subtle balance between ER alpha and ER beta. Mol Interv 3 (2003) 281-292
    • (2003) Mol Interv , vol.3 , pp. 281-292
    • Matthews, J.1    Gustafsson, J.A.2
  • 64
    • 0344586933 scopus 로고    scopus 로고
    • Uterine leiomyoma in the Eker rat: a unique model for important diseases of women
    • Walker C.L., Hunter D., and Everitt J.I. Uterine leiomyoma in the Eker rat: a unique model for important diseases of women. Genes Chromosomes Cancer 38 (2003) 349-356
    • (2003) Genes Chromosomes Cancer , vol.38 , pp. 349-356
    • Walker, C.L.1    Hunter, D.2    Everitt, J.I.3
  • 65
    • 34648843470 scopus 로고    scopus 로고
    • Identification of a sensitive period for developmental programming that increases risk for uterine leiomyoma in Eker rats
    • Cook J.D., Davis B.J., Goewey J.A., Berry T.D., and Walker C.L. Identification of a sensitive period for developmental programming that increases risk for uterine leiomyoma in Eker rats. Reprod Sci 14 (2007) 121-136
    • (2007) Reprod Sci , vol.14 , pp. 121-136
    • Cook, J.D.1    Davis, B.J.2    Goewey, J.A.3    Berry, T.D.4    Walker, C.L.5
  • 66
    • 23744513316 scopus 로고    scopus 로고
    • Expression profile of the tumorigenic factors associated with tumor size and sex steroid hormone status in uterine leiomyomata
    • Wei J.J., Chiriboga L., and Mittal K. Expression profile of the tumorigenic factors associated with tumor size and sex steroid hormone status in uterine leiomyomata. Fertil Steril 84 (2005) 474-484
    • (2005) Fertil Steril , vol.84 , pp. 474-484
    • Wei, J.J.1    Chiriboga, L.2    Mittal, K.3
  • 67
    • 0033664553 scopus 로고    scopus 로고
    • Advances in uterine leiomyoma research: the progesterone hypothesis
    • Rein M.S. Advances in uterine leiomyoma research: the progesterone hypothesis. Environ Health Perspect 108 Suppl 5 (2000) 791-793
    • (2000) Environ Health Perspect , vol.108 , Issue.SUPPL. 5 , pp. 791-793
    • Rein, M.S.1
  • 68
    • 17144409001 scopus 로고    scopus 로고
    • Aberrations in the progesterone receptor gene and the risk of recurrent endometrial carcinoma
    • Pijnenborg J.M., Romano A., Dam de Veen G.C., et al. Aberrations in the progesterone receptor gene and the risk of recurrent endometrial carcinoma. J Pathol 205 (2005) 597-605
    • (2005) J Pathol , vol.205 , pp. 597-605
    • Pijnenborg, J.M.1    Romano, A.2    Dam de Veen, G.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.