-
1
-
-
0036984640
-
Role of angiogenesis in tumor growth and metastasis
-
Folkman J. Role of angiogenesis in tumor growth and metastasis. Semin Oncol 2002;29:15-18.
-
(2002)
Semin Oncol
, vol.29
, pp. 15-18
-
-
Folkman, J.1
-
2
-
-
32944463899
-
Angiogenesis
-
Folkman J. Angiogenesis. Annu Rev Med 2006;57:1-18.
-
(2006)
Annu Rev Med
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
3
-
-
16844379997
-
Immunosuppressive networks in the tumour environment and their therapeutic relevance
-
Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer 2005;5:263-274.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 263-274
-
-
Zou, W.1
-
4
-
-
0035461919
-
Antiangiogenic scheduling of lower dose cancer chemotherapy
-
Gately S, Kerbel R. Antiangiogenic scheduling of lower dose cancer chemotherapy. Cancer J 2001;7:427-436.
-
(2001)
Cancer J
, vol.7
, pp. 427-436
-
-
Gately, S.1
Kerbel, R.2
-
5
-
-
2942615257
-
The anti-angiogenic basis of metronomic chemotherapy
-
Kerbel RS, Kamen BA. The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 2004;4:423-436.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 423-436
-
-
Kerbel, R.S.1
Kamen, B.A.2
-
6
-
-
0035865363
-
Redefining the target: Chemotherapeutics as antiangiogenics
-
Miller KD, Sweeney CJ, Sledge GW Jr. Redefining the target: Chemotherapeutics as antiangiogenics. J Clin Oncol 2001;19:1195-1206.
-
(2001)
J Clin Oncol
, vol.19
, pp. 1195-1206
-
-
Miller, K.D.1
Sweeney, C.J.2
Sledge Jr., G.W.3
-
7
-
-
11444266441
-
Cancer anti-angiogenic therapy
-
Shimizu K, Oku N. Cancer anti-angiogenic therapy. Biol Pharm Bull 2004;27:599-605.
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 599-605
-
-
Shimizu, K.1
Oku, N.2
-
8
-
-
27644436870
-
Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity
-
Shaked Y, Emmenegger U, Man S, et al. Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity. Blood 2005;106:3058-3061.
-
(2005)
Blood
, vol.106
, pp. 3058-3061
-
-
Shaked, Y.1
Emmenegger, U.2
Man, S.3
-
9
-
-
33646267928
-
From total empiricism to a rational design of metronomic chemotherapy phase I dosing trials
-
Lam T, Hetherington JW, Greenman J, et al. From total empiricism to a rational design of metronomic chemotherapy phase I dosing trials. Anticancer Drugs 2006;17:113-121.
-
(2006)
Anticancer Drugs
, vol.17
, pp. 113-121
-
-
Lam, T.1
Hetherington, J.W.2
Greenman, J.3
-
10
-
-
33745939679
-
Circulating endothelial cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy
-
Mancuso P, Colleoni M, Calleri A, et al. Circulating endothelial cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy. Blood 2006;108:452-459.
-
(2006)
Blood
, vol.108
, pp. 452-459
-
-
Mancuso, P.1
Colleoni, M.2
Calleri, A.3
-
11
-
-
0242331613
-
Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
-
Bocci G, Francia G, Man S, et al. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc Natl Acad Sci USA 2003;100:12917-12922.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12917-12922
-
-
Bocci, G.1
Francia, G.2
Man, S.3
-
12
-
-
10344220521
-
Endogenous angiogenesis inhibitors
-
Folkman J. Endogenous angiogenesis inhibitors. APMIS 2004;112:496-507.
-
(2004)
APMIS
, vol.112
, pp. 496-507
-
-
Folkman, J.1
-
13
-
-
33846441659
-
Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer
-
Kamat AA, Kim TJ, Landen CN Jr., et al. Metronomic chemotherapy enhances the efficacy of antivascular therapy in ovarian cancer. Cancer Res 2007;67:281-288.
-
(2007)
Cancer Res
, vol.67
, pp. 281-288
-
-
Kamat, A.A.1
Kim, T.J.2
Landen Jr., C.N.3
-
14
-
-
33846004208
-
Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: Creation of a beneficial host microenvironment involving type I IFNs and myeloid cells (1997)
-
Salem ML, Kadima AN, El-Naggar SA, et al. Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: Creation of a beneficial host microenvironment involving type I IFNs and myeloid cells (1997). J Immunother 2007;30:40-53.
-
(2007)
J Immunother
, vol.30
, pp. 40-53
-
-
Salem, M.L.1
Kadima, A.N.2
El-Naggar, S.A.3
-
15
-
-
0034030109
-
Mechanism of antimetastatic immunopotentiation by low-dose cyclophosphamide
-
Matar P, Rozados VR, Gonzalez AD, et al. Mechanism of antimetastatic immunopotentiation by low-dose cyclophosphamide. Eur J Cancer 2000;36:1060-1066.
-
(2000)
Eur J Cancer
, vol.36
, pp. 1060-1066
-
-
Matar, P.1
Rozados, V.R.2
Gonzalez, A.D.3
-
16
-
-
33847368549
-
Metronomic cyclophosphamide regimen selectively depletes CD4+ CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
-
Ghiringhelli F, Menard C, Puig PE, et al. Metronomic cyclophosphamide regimen selectively depletes CD4+ CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol Immunother 2007;56:641-648.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 641-648
-
-
Ghiringhelli, F.1
Menard, C.2
Puig, P.E.3
-
17
-
-
0042131613
-
Therapeutic potential of selective cyclooxygenase-2 inhibitors in the management of tumor angiogenesis
-
Gately S, Kerbel R. Therapeutic potential of selective cyclooxygenase-2 inhibitors in the management of tumor angiogenesis. Prog Exp Tumor Res 2003;37:179-192.
-
(2003)
Prog Exp Tumor Res
, vol.37
, pp. 179-192
-
-
Gately, S.1
Kerbel, R.2
-
18
-
-
0034530889
-
The contributions of cyclooxygenase-2 to tumor angiogenesis
-
Gately S. The contributions of cyclooxygenase-2 to tumor angiogenesis. Cancer Metastasis Rev 2000;19:19-27.
-
(2000)
Cancer Metastasis Rev
, vol.19
, pp. 19-27
-
-
Gately, S.1
-
19
-
-
0036468287
-
Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo
-
Leahy KM, Ornberg RL, Wang Y, et al. Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. Cancer Res 2002;62:625-631.
-
(2002)
Cancer Res
, vol.62
, pp. 625-631
-
-
Leahy, K.M.1
Ornberg, R.L.2
Wang, Y.3
-
20
-
-
0034161878
-
Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
-
Masferrer JL, Leahy KM, Koki AT, et al. Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res 2000;60:1306-1311.
-
(2000)
Cancer Res
, vol.60
, pp. 1306-1311
-
-
Masferrer, J.L.1
Leahy, K.M.2
Koki, A.T.3
-
21
-
-
43349104148
-
Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner
-
Yaqub S, Henjum K, Mahic M, et al. Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner. Cancer Immunol Immunother 2007;57:813-821.
-
(2007)
Cancer Immunol Immunother
, vol.57
, pp. 813-821
-
-
Yaqub, S.1
Henjum, K.2
Mahic, M.3
-
22
-
-
20444464066
-
Tumor cyclooxygenase-2/ prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer
-
Sharma S, Yang SC, Zhu L, et al. Tumor cyclooxygenase-2/ prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer. Cancer Res 2005;65:5211-5220.
-
(2005)
Cancer Res
, vol.65
, pp. 5211-5220
-
-
Sharma, S.1
Yang, S.C.2
Zhu, L.3
-
23
-
-
22544436066
-
Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells
-
Baratelli F, Lin Y, Zhu L, et al. Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J Immunol 2005;175:1483-1490.
-
(2005)
J Immunol
, vol.175
, pp. 1483-1490
-
-
Baratelli, F.1
Lin, Y.2
Zhu, L.3
-
24
-
-
33745311263
-
FOXP3+ CD4+ CD25+ adaptive regulatory T cells express cyclooxygenase-2 and suppress effector T cells by a prostaglandin E2-dependent mechanism
-
Mahic M, Yaqub S, Johansson CC, et al. FOXP3+ CD4+ CD25+ adaptive regulatory T cells express cyclooxygenase-2 and suppress effector T cells by a prostaglandin E2-dependent mechanism. J Immunol 2006;177:246-254.
-
(2006)
J Immunol
, vol.177
, pp. 246-254
-
-
Mahic, M.1
Yaqub, S.2
Johansson, C.C.3
-
25
-
-
33745794013
-
High-dose celecoxib and metronomic "low-dose" cyclophosphamide is an effective and safe therapy in patients with relapsed and refractory aggressive histology non-Hodgkin's lymphoma
-
Buckstein R, Kerbel RS, Shaked Y, et al. High-dose celecoxib and metronomic "low-dose" cyclophosphamide is an effective and safe therapy in patients with relapsed and refractory aggressive histology non-Hodgkin's lymphoma. Clin Cancer Res 2006;12:5190-5198.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5190-5198
-
-
Buckstein, R.1
Kerbel, R.S.2
Shaked, Y.3
-
26
-
-
0242329662
-
Metronomic oral low-dose treosulfan chemotherapy combined with cyclooxygenase-2 inhibitor in pretreated advanced melanoma: A pilot study
-
Spieth K, Kaufmann R, Gille J. Metronomic oral low-dose treosulfan chemotherapy combined with cyclooxygenase-2 inhibitor in pretreated advanced melanoma: A pilot study. Cancer Chemother Pharmacol 2003;52:377-382.
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, pp. 377-382
-
-
Spieth, K.1
Kaufmann, R.2
Gille, J.3
-
27
-
-
34547486126
-
Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults
-
Kesari S, Schiff D, Doherty L, et al. Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults. Neuro Oncol 2007;9:354-363.
-
(2007)
Neuro Oncol
, vol.9
, pp. 354-363
-
-
Kesari, S.1
Schiff, D.2
Doherty, L.3
-
28
-
-
0037081169
-
Effects of the cyclooxygenase inhibitor, piroxicam, on tumor response, apoptosis, and angiogenesis in a canine model of human invasive urinary bladder cancer
-
Mohammed SI, Bennett PF, Craig BA, et al. Effects of the cyclooxygenase inhibitor, piroxicam, on tumor response, apoptosis, and angiogenesis in a canine model of human invasive urinary bladder cancer. Cancer Res 2002;62:356-358.
-
(2002)
Cancer Res
, vol.62
, pp. 356-358
-
-
Mohammed, S.I.1
Bennett, P.F.2
Craig, B.A.3
-
29
-
-
0038784210
-
Antitumor effects of piroxicam in spontaneous canine invasive urinary bladder cancer, a relevant model of human invasive bladder cancer
-
Knapp DW, Glickman NW, Mohammed SI, et al. Antitumor effects of piroxicam in spontaneous canine invasive urinary bladder cancer, a relevant model of human invasive bladder cancer. Adv Exp Med Biol 2002;507:377-380.
-
(2002)
Adv Exp Med Biol
, vol.507
, pp. 377-380
-
-
Knapp, D.W.1
Glickman, N.W.2
Mohammed, S.I.3
-
30
-
-
0028477323
-
Piroxicam therapy in 34 dogs with transitional cell carcinoma of the urinary bladder
-
Knapp DW, Richardson RC, Chan TC, et al. Piroxicam therapy in 34 dogs with transitional cell carcinoma of the urinary bladder. J Vet Intern Med 1994;8:273-278.
-
(1994)
J Vet Intern Med
, vol.8
, pp. 273-278
-
-
Knapp, D.W.1
Richardson, R.C.2
Chan, T.C.3
-
31
-
-
0029066652
-
Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells
-
Knapp DW, Chan TC, Kuczek T, et al. Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells. Am J Vet Res 1995;56:801-805.
-
(1995)
Am J Vet Res
, vol.56
, pp. 801-805
-
-
Knapp, D.W.1
Chan, T.C.2
Kuczek, T.3
-
32
-
-
35548986259
-
Evaluation of cisplatin administered with piroxicam in dogs with transitional cell carcinoma of the urinary bladder
-
Greene SN, Lucroy MD, Greenberg CB, et al. Evaluation of cisplatin administered with piroxicam in dogs with transitional cell carcinoma of the urinary bladder. J Am Vet Med Assoc 2007;231:1056-1060.
-
(2007)
J Am Vet Med Assoc
, vol.231
, pp. 1056-1060
-
-
Greene, S.N.1
Lucroy, M.D.2
Greenberg, C.B.3
-
33
-
-
34547818190
-
Continuous low-dose oral chemotherapy for adjuvant therapy of splenic hemangiosarcoma in dogs
-
Lana S, U'Ren L, Plaza S, et al. Continuous low-dose oral chemotherapy for adjuvant therapy of splenic hemangiosarcoma in dogs. J Vet Intern Med 2007;21:764-769.
-
(2007)
J Vet Intern Med
, vol.21
, pp. 764-769
-
-
Lana, S.1
U'Ren, L.2
Plaza, S.3
-
36
-
-
0031604963
-
Soft tissue sarcomas
-
Withrow SJ. Soft tissue sarcomas. Vet Q 1998;20(Suppl 1):S16-S17.
-
(1998)
Vet Q
, vol.20
, Issue.SUPPL. 1
-
-
Withrow, S.J.1
-
37
-
-
0034328522
-
Postoperative radiotherapy for canine soft tissue sarcoma
-
Forrest LJ, Chun R, Adams WM, et al. Postoperative radiotherapy for canine soft tissue sarcoma. J Vet Intern Med 2000;14:578-582.
-
(2000)
J Vet Intern Med
, vol.14
, pp. 578-582
-
-
Forrest, L.J.1
Chun, R.2
Adams, W.M.3
-
38
-
-
0033671255
-
Spontaneously occurring tumors of companion animals as models for human cancer
-
Vail DM, MacEwen EG. Spontaneously occurring tumors of companion animals as models for human cancer. Cancer Invest 2000;18:781-792.
-
(2000)
Cancer Invest
, vol.18
, pp. 781-792
-
-
Vail, D.M.1
MacEwen, E.G.2
-
39
-
-
33751218313
-
A pilot pharmacokinetic and antiangiogenic biomarker study of celecoxib and low-dose metronomic vinblastine or cyclophosphamide in pediatric recurrent solid tumors
-
Stempak D, Gammon J, Halton J, et al. A pilot pharmacokinetic and antiangiogenic biomarker study of celecoxib and low-dose metronomic vinblastine or cyclophosphamide in pediatric recurrent solid tumors. J Pediatr Hematol Oncol 2006;28:720-728.
-
(2006)
J Pediatr Hematol Oncol
, vol.28
, pp. 720-728
-
-
Stempak, D.1
Gammon, J.2
Halton, J.3
-
40
-
-
33745213573
-
Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation
-
Lamerato-Kozicki AR, Helm KM, Jubala CM, et al. Canine hemangiosarcoma originates from hematopoietic precursors with potential for endothelial differentiation. Exp Hematol 2006;34:870-878.
-
(2006)
Exp Hematol
, vol.34
, pp. 870-878
-
-
Lamerato-Kozicki, A.R.1
Helm, K.M.2
Jubala, C.M.3
-
41
-
-
18944379083
-
Can a rational design for metronomic chemotherapy dosing be devised?
-
Maraveyas A, Lam T, Hetherington JW, et al. Can a rational design for metronomic chemotherapy dosing be devised? Br J Cancer 2005;92:1588-1590.
-
(2005)
Br J Cancer
, vol.92
, pp. 1588-1590
-
-
Maraveyas, A.1
Lam, T.2
Hetherington, J.W.3
-
42
-
-
34548070466
-
Pharmacodynamic and pharmacokinetic study of chronic low-dose metronomic cyclophosphamide therapy in mice
-
Emmenegger U, Shaked Y, Man S, et al. Pharmacodynamic and pharmacokinetic study of chronic low-dose metronomic cyclophosphamide therapy in mice. Mol Cancer Ther 2007;6:2280-2289.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2280-2289
-
-
Emmenegger, U.1
Shaked, Y.2
Man, S.3
-
43
-
-
33847152638
-
Use of FoxP3 expression to identify regulatory T cells in healthy dogs and dogs with cancer
-
Biller BJ, Elmslie RE, Burnett RC, et al. Use of FoxP3 expression to identify regulatory T cells in healthy dogs and dogs with cancer. Vet Immunol Immunopathol 2007;116:69-78.
-
(2007)
Vet Immunol Immunopathol
, vol.116
, pp. 69-78
-
-
Biller, B.J.1
Elmslie, R.E.2
Burnett, R.C.3
-
44
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel TJ, Coukos G, Zou L, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 2004;10:942-949.
-
(2004)
Nat Med
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
-
45
-
-
0037950422
-
Risk factors for sterile hemorrhagic cystitis in dogs with lymphoma receiving cyclophosphamide with or without concurrent administration of furosemide: 216 cases (1990-1996)
-
Charney SC, Bergman PJ, Hohenhaus AE, et al. Risk factors for sterile hemorrhagic cystitis in dogs with lymphoma receiving cyclophosphamide with or without concurrent administration of furosemide: 216 cases (1990-1996). J Am Vet Med Assoc 2003;222:1388-1393.
-
(2003)
J Am Vet Med Assoc
, vol.222
, pp. 1388-1393
-
-
Charney, S.C.1
Bergman, P.J.2
Hohenhaus, A.E.3
-
46
-
-
23844538059
-
Low-dose metronomic combined with intermittent bolus-dose cyclophosphamide is an effective long-term chemotherapy treatment strategy
-
Shaked Y, Emmenegger U, Francia G, et al. Low-dose metronomic combined with intermittent bolus-dose cyclophosphamide is an effective long-term chemotherapy treatment strategy. Cancer Res 2005;65:7045-7051.
-
(2005)
Cancer Res
, vol.65
, pp. 7045-7051
-
-
Shaked, Y.1
Emmenegger, U.2
Francia, G.3
|