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Volumn 2, Issue 4, 2008, Pages 429-439

Primary prophylaxis of gastroesophageal variceal bleeding: Consensus recommendations of the Asian Pacific Association for the Study of the Liver

Author keywords

Cirrhosis; GI bleed; Guidelines; Varices

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; ENBUCRILATE; ISOSORBIDE 5 NITRATE; NADOLOL; NONSTEROID ANTIINFLAMMATORY AGENT; OCTREOTIDE; PLACEBO; PROPRANOLOL; PROTON PUMP INHIBITOR; SUCRALFATE; TIMOLOL;

EID: 57149113717     PISSN: 19360533     EISSN: 19360541     Source Type: Journal    
DOI: 10.1007/s12072-008-9096-8     Document Type: Review
Times cited : (36)

References (106)
  • 1
    • 20444415957 scopus 로고    scopus 로고
    • Evolving Consensus in Portal Hypertension Report of the Baveno IV Consensus Workshop on methodology of diagnosis and therapy in portal hypertension
    • de Franchis R. Evolving Consensus in Portal Hypertension Report of the Baveno IV Consensus Workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol 2005;43:167-176
    • (2005) J Hepatol , vol.43 , pp. 167-176
    • de Franchis, R.1
  • 2
    • 34548802928 scopus 로고    scopus 로고
    • Practice Guidelines Committee of the American Association for the Study of Liver Diseases. Practice Parameters Committee of the American College of Gastroenterology. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis
    • doi: 10.1002/hep.21907
    • Garcia-Tsao G, Sanyal AJ, Grace ND, Carey W. Practice Guidelines Committee of the American Association for the Study of Liver Diseases. Practice Parameters Committee of the American College of Gastroenterology. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Hepatology 2007;46(3):922-938. doi: 10.1002/hep.21907
    • (2007) Hepatology , vol.46 , Issue.3 , pp. 922-938
    • Garcia-Tsao, G.1    Sanyal, A.J.2    Grace, N.D.3    Carey, W.4
  • 3
    • 0030834097 scopus 로고    scopus 로고
    • Diagnosis and treatment of gastrointestinal bleeding secondary to portal hypertension
    • Grace ND. Diagnosis and treatment of gastrointestinal bleeding secondary to portal hypertension. Am J Gastroenterol 1997;92:1081-1091
    • (1997) Am J Gastroenterol , vol.92 , pp. 1081-1091
    • Grace, N.D.1
  • 5
    • 0026773235 scopus 로고
    • Definitions, methodology and therapeutic strategies in portal hypertension. A consensus development workshop
    • doi: 10.1016/0168-8278(92)90044-P
    • de Franchis R, Pascal JP, Burroughs AK, Henderson JM, Fleig W, Groszmann RJ, et al. Definitions, methodology and therapeutic strategies in portal hypertension. A consensus development workshop. J Hepatol 1992;15:256-261. doi: 10.1016/0168-8278(92)90044-P
    • (1992) J Hepatol , vol.15 , pp. 256-261
    • de Franchis, R.1    Pascal, J.P.2    Burroughs, A.K.3    Henderson, J.M.4    Fleig, W.5    Groszmann, R.J.6
  • 6
    • 0031721522 scopus 로고    scopus 로고
    • Portal hypertension and variceal bleeding: An AASLD single topic symposium
    • doi: 10.1002/hep.510280339
    • Grace ND, Groszmann RJ, Garcia-Tsao G, Burroughs AK, Pagliaro L, Makuch RW, et al. Portal hypertension and variceal bleeding: An AASLD single topic symposium. Hepatology 1998;28:868-880. doi: 10.1002/hep.510280339
    • (1998) Hepatology , vol.28 , pp. 868-880
    • Grace, N.D.1    Groszmann, R.J.2    Garcia-Tsao, G.3    Burroughs, A.K.4    Pagliaro, L.5    Makuch, R.W.6
  • 8
    • 0023681215 scopus 로고
    • The North Italian Endoscopic Club for the Study and Treatment of Esophageal Varices. Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. A prospective multicenter study
    • The North Italian Endoscopic Club for the Study and Treatment of Esophageal Varices. Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. A prospective multicenter study. N Engl J Med 1988;319:983-989
    • (1988) N Engl J Med , vol.319 , pp. 983-989
  • 9
    • 0033637225 scopus 로고    scopus 로고
    • Improved survival after variceal hemorrhage over an 11-year period in the Department of Veterans Affairs
    • doi: 10.1111/j.1572-0241.2000.03376.x
    • El-Serag HB, Everhart JE. Improved survival after variceal hemorrhage over an 11-year period in the Department of Veterans Affairs. Am J Gastroenterol 2000;95:3566-3573. doi: 10.1111/j.1572-0241.2000.03376.x
    • (2000) Am J Gastroenterol , vol.95 , pp. 3566-3573
    • El-Serag, H.B.1    Everhart, J.E.2
  • 10
    • 0042322991 scopus 로고    scopus 로고
    • Upper digestive bleeding in cirrhosis. Posttherapeutic outcome and prognostic indicators
    • doi: 10.1053/jhep.2003.50385
    • D'Amico G, de Franchis R. Upper digestive bleeding in cirrhosis. Posttherapeutic outcome and prognostic indicators. Hepatology 2003;38:599-612. doi: 10.1053/jhep.2003.50385
    • (2003) Hepatology , vol.38 , pp. 599-612
    • D'Amico, G.1    de Franchis, R.2
  • 11
    • 4544261930 scopus 로고    scopus 로고
    • Improved survival after variceal bleeding in patients with cirrhosis over the past two decades
    • doi: 10.1002/hep.20339
    • Carbonell N, Pauwels A, Serfaty L, Fourdan O, Levy VG, Poupon R. Improved survival after variceal bleeding in patients with cirrhosis over the past two decades. Hepatology 2004;40:652-659. doi: 10.1002/ hep.20339
    • (2004) Hepatology , vol.40 , pp. 652-659
    • Carbonell, N.1    Pauwels, A.2    Serfaty, L.3    Fourdan, O.4    Levy, V.G.5    Poupon, R.6
  • 12
    • 0032870515 scopus 로고    scopus 로고
    • Prognostic value of early measurements of portal pressure in acute variceal bleeding
    • doi: 10.1016/S0016-5085(99)70455-5
    • Moitinho E, Escorsell A, Bandi JC, Salmeron JM, Garcia-Pagan JC, Rodes J, et al. Prognostic value of early measurements of portal pressure in acute variceal bleeding. Gastroenterology 1999;117:626-631. doi: 10.1016/ S0016-5085(99)70455-5
    • (1999) Gastroenterology , vol.117 , pp. 626-631
    • Moitinho, E.1    Escorsell, A.2    Bandi, J.C.3    Salmeron, J.M.4    Garcia-Pagan, J.C.5    Rodes, J.6
  • 13
    • 28144455912 scopus 로고    scopus 로고
    • Betablockers to prevent gastroesophageal varices in patients with cirrhosis
    • Portal Hypertension Collaborative Group. doi: 10.1056/NEJMoa044456
    • Groszmann RJ, Garcia-Tsao G, Bosch J, Grace ND, Burroughs AK, Planas R, et al. Portal Hypertension Collaborative Group. Betablockers to prevent gastroesophageal varices in patients with cirrhosis. N Engl J Med 2005;353:2254-2261. doi: 10.1056/NEJMoa044456
    • (2005) N Engl J Med , vol.353 , pp. 2254-2261
    • Groszmann, R.J.1    Garcia-Tsao, G.2    Bosch, J.3    Grace, N.D.4    Burroughs, A.K.5    Planas, R.6
  • 14
    • 1442282026 scopus 로고    scopus 로고
    • Noninvasive markers of esophageal varices: Another round, not the last
    • doi: 10.1002/hep.20018
    • D'Amico G, Morabito A. Noninvasive markers of esophageal varices: another round, not the last. Hepatology 2004;39:30-34. doi: 10.1002/ hep.20018
    • (2004) Hepatology , vol.39 , pp. 30-34
    • D'Amico, G.1    Morabito, A.2
  • 15
    • 30744441666 scopus 로고    scopus 로고
    • The accuracy of PillCam ESO capsule endoscopy versus conventional upper endoscopy for the diagnosis of esophageal varices: A prospective three-center pilot study
    • doi: 10.1055/s-2005-921189
    • Eisen GM, Eliakim R, Zaman A, Schwartz J, Faigel D, Rondonotti E, et al. The accuracy of PillCam ESO capsule endoscopy versus conventional upper endoscopy for the diagnosis of esophageal varices: A prospective three-center pilot study. Endoscopy 2006;38:31-35. doi: 10.1055/ s-2005-921189
    • (2006) Endoscopy , vol.38 , pp. 31-35
    • Eisen, G.M.1    Eliakim, R.2    Zaman, A.3    Schwartz, J.4    Faigel, D.5    Rondonotti, E.6
  • 16
    • 30744446764 scopus 로고    scopus 로고
    • Esophageal capsule endoscopy versus esophagogastroduodenoscopy for evaluating portal hypertension: A prospective comparative study of performance and tolerance
    • doi: 10.1055/s-2006-924975
    • Lapalus MG, Dumortier J, Fumex F, Roman S, Lot M, Prost B, et al. Esophageal capsule endoscopy versus esophagogastroduodenoscopy for evaluating portal hypertension: A prospective comparative study of performance and tolerance. Endoscopy 2006;38:36-41. doi: 10.1055/ s-2006-924975
    • (2006) Endoscopy , vol.38 , pp. 36-41
    • Lapalus, M.G.1    Dumortier, J.2    Fumex, F.3    Roman, S.4    Lot, M.5    Prost, B.6
  • 17
    • 0023143115 scopus 로고
    • Reliability of endoscopy in the assessment of variceal features: The Italian Liver Cirrhosis Project
    • doi: 10.1016/S0168-8278(87)80015-6
    • Reliability of endoscopy in the assessment of variceal features: The Italian Liver Cirrhosis Project. J Hepatol 1987;4:93-98. doi: 10.1016/ S0168-8278(87)80015-6
    • (1987) J Hepatol , vol.4 , pp. 93-98
  • 18
    • 0033118990 scopus 로고    scopus 로고
    • Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding
    • doi: 10.1056/NEJM199904013401302
    • Sarin S, Lamba GS, Kumar M, Misra A, Murthy NS. Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding. N Engl J Med 1999;340:988-993. doi: 10.1056/NEJM199904013401302
    • (1999) N Engl J Med , vol.340 , pp. 988-993
    • Sarin, S.1    Lamba, G.S.2    Kumar, M.3    Misra, A.4    Murthy, N.S.5
  • 19
    • 0037336548 scopus 로고    scopus 로고
    • Incidence and natural history of small esophageal varices in cirrhotic patients
    • doi: 10.1016/S0168-8278(02)00420-8
    • Merli M, Nicolini G, Angeloni S, Rinaldi V, De Santis A, Merkel C, et al. Incidence and natural history of small esophageal varices in cirrhotic patients. J Hepatol 2003;38:266-272. doi: 10.1016/ S0168-8278(02)00420-8
    • (2003) J Hepatol , vol.38 , pp. 266-272
    • Merli, M.1    Nicolini, G.2    Angeloni, S.3    Rinaldi, V.4    De Santis, A.5    Merkel, C.6
  • 20
    • 0025830767 scopus 로고
    • Propranolol in the prevention of the first hemorrhage from esophagogastric varices: A multicenter, randomized clinical trial
    • Conn HO, Grace ND, Bosch J, Groszmann J, Rodes J, Wright SC, et al. Propranolol in the prevention of the first hemorrhage from esophagogastric varices: A multicenter, randomized clinical trial. Hepatology 1991;13:902-912
    • (1991) Hepatology , vol.13 , pp. 902-912
    • Conn, H.O.1    Grace, N.D.2    Bosch, J.3    Groszmann, J.4    Rodes, J.5    Wright, S.C.6
  • 21
    • 0026337703 scopus 로고
    • Prophylaxis of first hemorrhage from esophageal varices by sclerotherapy, propranolol or both in cirrhotic patients. A randomized multicenter trial
    • The PROVA Study Group
    • The PROVA Study Group. Prophylaxis of first hemorrhage from esophageal varices by sclerotherapy, propranolol or both in cirrhotic patients. A randomized multicenter trial. Hepatology 1991;14:1016-1024
    • (1991) Hepatology , vol.14 , pp. 1016-1024
  • 22
    • 0030781407 scopus 로고    scopus 로고
    • Effects of isosorbide-5-mononitrate compared with propranolol on first bleeding and long-term survival in cirrhosis
    • doi: 10.1053/gast.1997.v113.pm9352866
    • Angelico M, Carli L, Piat C, Gentile S, Capocaccia L. Effects of isosorbide-5-mononitrate compared with propranolol on first bleeding and long-term survival in cirrhosis. Gastroenterology 1997;113:1632-1639. doi: 10.1053/gast.1997.v113.pm9352866
    • (1997) Gastroenterology , vol.113 , pp. 1632-1639
    • Angelico, M.1    Carli, L.2    Piat, C.3    Gentile, S.4    Capocaccia, L.5
  • 23
    • 0034792003 scopus 로고    scopus 로고
    • Mononitrato Varices Esofagicas: Isosorbide mononitrate in the prevention of first variceal bleed in patients who cannot receive beta-blockers
    • doi: 10.1053/gast.2001.27993
    • Garcia-Pagan JC, Villanueva C, Vila MC, Albillos A, Genesca J, Ruiz del Arbol L, et al. Mononitrato Varices Esofagicas: Isosorbide mononitrate in the prevention of first variceal bleed in patients who cannot receive beta-blockers. Gastroenterology 2001;121:908-914. doi: 10.1053/ gast.2001.27993
    • (2001) Gastroenterology , vol.121 , pp. 908-914
    • Garcia-Pagan, J.C.1    Villanueva, C.2    Vila, M.C.3    Albillos, A.4    Genesca, J.5    Ruiz del Arbol, L.6
  • 24
    • 17544362526 scopus 로고    scopus 로고
    • Long-term results of a clinical trial of nadolol with or without isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis
    • doi: 10.1002/hep.510310210
    • Merkel C, Marin R, Sacerdoti D, Donada C, Cavallarin G, Torboli P, et al. Long-term results of a clinical trial of nadolol with or without isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis. Hepatology 2000;31:324-329. doi: 10.1002/hep.510310210
    • (2000) Hepatology , vol.31 , pp. 324-329
    • Merkel, C.1    Marin, R.2    Sacerdoti, D.3    Donada, C.4    Cavallarin, G.5    Torboli, P.6
  • 25
    • 0032785468 scopus 로고    scopus 로고
    • Lack of effect of propranolol in the prevention of large oesophageal varices in patients with cirrhosis: A randomized trial. French-speaking Club for the study of portal hypertension
    • doi: 10.1097/00042737-199907000-00011
    • Cales P, Oberti F, Payen JL, Naveau S, Guyader D, Blanc P, et al. Lack of effect of propranolol in the prevention of large oesophageal varices in patients with cirrhosis: A randomized trial. French-speaking Club for the study of portal hypertension. Eur J Gastroenterol Hepatol 1999;11:741-745. doi: 10.1097/00042737-199907000-00011
    • (1999) Eur J Gastroenterol Hepatol , vol.11 , pp. 741-745
    • Cales, P.1    Oberti, F.2    Payen, J.L.3    Naveau, S.4    Guyader, D.5    Blanc, P.6
  • 26
    • 4143109070 scopus 로고    scopus 로고
    • A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis
    • doi: 10.1053/j.gastro.2004.05.004
    • Merkel C, Marin R, Angeli P, Zanella P, Felder M, Bernardinello E, et al. A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis. Gastroenterology 2004;127:476-484. doi: 10.1053/j.gastro.2004.05.004 476-484.
    • (2004) Gastroenterology , vol.127 , pp. 476-484
    • Merkel, C.1    Marin, R.2    Angeli, P.3    Zanella, P.4    Felder, M.5    Bernardinello, E.6
  • 27
    • 0021878556 scopus 로고
    • Intravascular oesophageal variceal pressure (IOVP) assessed by endoscopic fine needle puncture under basal conditions, Valsalva's manoeuvre and after glyceryltrinitrate application
    • doi: 10.1136/gut.26.5.525
    • Staritz M, Poralla T, Meyer zum Büschenfelde KH. Intravascular oesophageal variceal pressure (IOVP) assessed by endoscopic fine needle puncture under basal conditions, Valsalva's manoeuvre and after glyceryltrinitrate application. Gut 1985;26(5):525-530. doi: 10.1136/ gut.26.5.525
    • (1985) Gut , vol.26 , Issue.5 , pp. 525-530
    • Staritz, M.1    Poralla, T.2    Meyer zum Büschenfelde, K.H.3
  • 28
    • 0031012354 scopus 로고    scopus 로고
    • Total volume paracentesis decreases variceal pressure, size, and variceal wall tension in cirrhotic patients
    • doi: 10.1002/hep.510250111
    • Kravetz D, Romero G, Argonz J, Guevara M, Suarez A, Abecasis R, et al. Total volume paracentesis decreases variceal pressure, size, and variceal wall tension in cirrhotic patients. Hepatology 1997;25(1):59-62. doi: 10.1002/hep.510250111
    • (1997) Hepatology , vol.25 , Issue.1 , pp. 59-62
    • Kravetz, D.1    Romero, G.2    Argonz, J.3    Guevara, M.4    Suarez, A.5    Abecasis, R.6
  • 29
    • 0028237009 scopus 로고
    • Favorable effects of total paracentesis on splanchnic hemodynamics in cirrhotic patients with tense ascites
    • Luca A, Feu F, García-Pagán JC, Jiménez W, Arroyo V, Bosch J, et al. Favorable effects of total paracentesis on splanchnic hemodynamics in cirrhotic patients with tense ascites. Hepatology 1994;20(1 Pt 1):30-33
    • (1994) Hepatology , vol.20 , Issue.1 PART 1 , pp. 30-33
    • Luca, A.1    Feu, F.2    García-Pagán, J.C.3    Jiménez, W.4    Arroyo, V.5    Bosch, J.6
  • 30
    • 0036787603 scopus 로고    scopus 로고
    • Increasing intra-abdominal pressure increases pressure, volume, and wall tension in esophageal varices
    • Escorsell A, Ginès A, Llach J, García-Pagán JC, Bordas JM, Bosch J, et al. Increasing intra-abdominal pressure increases pressure, volume, and wall tension in esophageal varices. Hepatology 2002;36(4 Pt 1):936-940
    • (2002) Hepatology , vol.36 , Issue.4 PART 1 , pp. 936-940
    • Escorsell, A.1    Ginès, A.2    Llach, J.3    García-Pagán, J.C.4    Bordas, J.M.5    Bosch, J.6
  • 31
    • 0027509995 scopus 로고
    • Hemodynamic effects of acute changes in intra-abdominal pressure in patients with cirrhosis
    • Luca A, Cirera I, García-Pagán JC, Feu F, Pizcueta P, Bosch J, et al. Hemodynamic effects of acute changes in intra-abdominal pressure in patients with cirrhosis. Gastroenterology 1993;104(1):222-227
    • (1993) Gastroenterology , vol.104 , Issue.1 , pp. 222-227
    • Luca, A.1    Cirera, I.2    García-Pagán, J.C.3    Feu, F.4    Pizcueta, P.5    Bosch, J.6
  • 32
    • 0029827013 scopus 로고    scopus 로고
    • Physical exercise increases portal pressure in patients with cirrhosis and portal hypertension
    • doi: 10.1053/gast.1996.v111.pm8898644
    • García-Pagàn JC, Santos C, Barberá JA, Luca A, Roca J, Rodriguez-Roisin R, et al. Physical exercise increases portal pressure in patients with cirrhosis and portal hypertension. Gastroenterology 1996;111(5):1300-1306. doi: 10.1053/ gast.1996.v111.pm8898644
    • (1996) Gastroenterology , vol.111 , Issue.5 , pp. 1300-1306
    • García-Pagàn, J.C.1    Santos, C.2    Barberá, J.A.3    Luca, A.4    Roca, J.5    Rodriguez-Roisin, R.6
  • 33
    • 0031721142 scopus 로고    scopus 로고
    • Effects of propranolol on the hepatic hemodynamic response to physical exercise in patients with cirrhosis
    • doi: 10.1002/hep.510280312
    • Bandi JC, García-Pagán JC, Escorsell A, François E, Moitinho E, Rodés J, et al. Effects of propranolol on the hepatic hemodynamic response to physical exercise in patients with cirrhosis. Hepatology 1998;28(3):677-682. doi: 10.1002/hep.510280312
    • (1998) Hepatology , vol.28 , Issue.3 , pp. 677-682
    • Bandi, J.C.1    García-Pagán, J.C.2    Escorsell, A.3    François, E.4    Moitinho, E.5    Rodés, J.6
  • 34
    • 0027378835 scopus 로고
    • Reduction of variceal pressure by propranolol: Comparison of the effects on portal pressure and azygos blood flow in patients with cirrhosis
    • Feu F, Bordas JM, Luca A, García-Pagán JC, Escorsell A, Bosch J, et al. Reduction of variceal pressure by propranolol: comparison of the effects on portal pressure and azygos blood flow in patients with cirrhosis. Hepatology 1993;18(5):1082-1089
    • (1993) Hepatology , vol.18 , Issue.5 , pp. 1082-1089
    • Feu, F.1    Bordas, J.M.2    Luca, A.3    García-Pagán, J.C.4    Escorsell, A.5    Bosch, J.6
  • 35
    • 0031006514 scopus 로고    scopus 로고
    • Effects of ethanol consumption on hepatic hemodynamics in patients with alcoholic cirrhosis
    • doi: 10.1016/S0016-5085(97)70142-2
    • Luca A, García-Pagán JC, Bosch J, Feu F, Caballeráa J, Groszmann RJ, et al. Effects of ethanol consumption on hepatic hemodynamics in patients with alcoholic cirrhosis. Gastroenterology 1997;112(4):1284-1289. doi: 10.1016/S0016-5085(97)70142-2
    • (1997) Gastroenterology , vol.112 , Issue.4 , pp. 1284-1289
    • Luca, A.1    García-Pagán, J.C.2    Bosch, J.3    Feu, F.4    Caballeráa, J.5    Groszmann, R.J.6
  • 36
    • 0025355599 scopus 로고
    • The effects of ethanol administration on portal pressure and gastroesophageal collateral blood flow in patients with alcoholic cirrhosis
    • doi: 10.1002/hep.1840110422
    • Ready JB, Hossack KF, Rector WG Jr. The effects of ethanol administration on portal pressure and gastroesophageal collateral blood flow in patients with alcoholic cirrhosis. Hepatology 1990;11(4):674-677. doi: 10.1002/hep.1840110422
    • (1990) Hepatology , vol.11 , Issue.4 , pp. 674-677
    • Ready, J.B.1    Hossack, K.F.2    Rector Jr., W.G.3
  • 37
    • 33847008087 scopus 로고    scopus 로고
    • The extent of the collateral circulation influences the postprandial increase in portal pressure in patients with cirrhosis
    • doi: 10.1136/gut.2006.095240
    • Albillos A, Bañares R, González M, Catalina MV, Pastor O, Gonzalez R, et al. The extent of the collateral circulation influences the postprandial increase in portal pressure in patients with cirrhosis. Gut 2007;56(2):259-264. doi: 10.1136/gut.2006.095240
    • (2007) Gut , vol.56 , Issue.2 , pp. 259-264
    • Albillos, A.1    Bañares, R.2    González, M.3    Catalina, M.V.4    Pastor, O.5    Gonzalez, R.6
  • 38
    • 0027932941 scopus 로고
    • Octreotide prevents postprandial splanchnic hyperemia in patients with portal hypertension
    • doi: 10.1016/S0168-8278(94)80142-8
    • Albillos A, Rossi I, Iborra J, Lledó JL, Calleja JL, Barrios C, et al. Octreotide prevents postprandial splanchnic hyperemia in patients with portal hypertension. J Hepatol 1994;21(1):88-94. doi: 10.1016/ S0168-8278(94)80142-8
    • (1994) J Hepatol , vol.21 , Issue.1 , pp. 88-94
    • Albillos, A.1    Rossi, I.2    Iborra, J.3    Lledó, J.L.4    Calleja, J.L.5    Barrios, C.6
  • 39
    • 0034006836 scopus 로고    scopus 로고
    • 48-hour hemodynamic effects of octreotide on postprandial splanchnic hyperemia in patients with liver cirrhosis and portal hypertension: Double-blind, placebo-controlled study
    • doi: 10.1023/A:1005553914878
    • Ludwig D, Schädel S, Brúning A, Schiefer B, Stange EF. 48-hour hemodynamic effects of octreotide on postprandial splanchnic hyperemia in patients with liver cirrhosis and portal hypertension: double-blind, placebo-controlled study. Dig Dis Sci 2000;45(5):1019-1027. doi: 10.1023/A:1005553914878
    • (2000) Dig Dis Sci , vol.45 , Issue.5 , pp. 1019-1027
    • Ludwig, D.1    Schädel, S.2    Brúning, A.3    Schiefer, B.4    Stange, E.F.5
  • 40
    • 0028874266 scopus 로고
    • Octreotide blunts postprandial splanchnic hyperemia in cirrhotic patients: A double-blind randomized echo-Doppler study
    • Buonamico P, Sabbá C, Garcia-Tsao G, Berardi E, Antonica G, Ferraioli G, et al. Octreotide blunts postprandial splanchnic hyperemia in cirrhotic patients: A double-blind randomized echo-Doppler study. Hepatology 1995;21(1):134-139
    • (1995) Hepatology , vol.21 , Issue.1 , pp. 134-139
    • Buonamico, P.1    Sabbá, C.2    Garcia-Tsao, G.3    Berardi, E.4    Antonica, G.5    Ferraioli, G.6
  • 41
    • 17344375338 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs and variceal bleeding: A case-control study
    • doi: 10.1016/S0168-8278(96)80142-5
    • de Lédinghen V, Mannant PR, Foucher J, Perault MC, Barrioz T, Ingrand P, et al. Non-steroidal anti-inflammatory drugs and variceal bleeding: A case-control study. J Hepatol 1996;24(5):570-573. doi: 10.1016/S0168-8278(96)80142-5
    • (1996) J Hepatol , vol.24 , Issue.5 , pp. 570-573
    • de Lédinghen, V.1    Mannant, P.R.2    Foucher, J.3    Perault, M.C.4    Barrioz, T.5    Ingrand, P.6
  • 43
    • 1542499818 scopus 로고    scopus 로고
    • Systemic and splanchnic haemodynamic effects of sildenafil in an in vivo animal model of cirrhosis support for a risk in cirrhotic patients
    • doi: 10.1111/j.1478-3231.2004.00892.x
    • Colle I, De Vriese AS, Van Vlierberghe H, Lameire NH, DeVos M. Systemic and splanchnic haemodynamic effects of sildenafil in an in vivo animal model of cirrhosis support for a risk in cirrhotic patients. Liver Int 2004;24(1):63-68. doi: 10.1111/j.1478-3231.2004.00892.x
    • (2004) Liver Int , vol.24 , Issue.1 , pp. 63-68
    • Colle, I.1    De Vriese, A.S.2    Van Vlierberghe, H.3    Lameire, N.H.4    DeVos, M.5
  • 44
    • 0025810312 scopus 로고
    • Betaadrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices. An analysis of data and prognostic factors in 589 patients from four randomized clinical trials
    • Franco-Italian Multicenter Study Group
    • Poynard T, Cales P, Pasta L, Ideo G, Pascal JP, Pagliaro L, et al. Betaadrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices. An analysis of data and prognostic factors in 589 patients from four randomized clinical trials, Franco-Italian Multicenter Study Group. N Engl J Med 1991;324:1532-1538
    • (1991) N Engl J Med , vol.324 , pp. 1532-1538
    • Poynard, T.1    Cales, P.2    Pasta, L.3    Ideo, G.4    Pascal, J.P.5    Pagliaro, L.6
  • 45
    • 0026762376 scopus 로고
    • Prevention of first bleeding in cirrhosis. A meta-analysis of randomized trials of nonsurgical treatment
    • Pagliaro L, D'Amico G, Sorensen TI, Lebrec D, Burroughs AK, Morabito A, et al. Prevention of first bleeding in cirrhosis. A meta-analysis of randomized trials of nonsurgical treatment. Ann Intern Med 1992;117:59-70
    • (1992) Ann Intern Med , vol.117 , pp. 59-70
    • Pagliaro, L.1    D'Amico, G.2    Sorensen, T.I.3    Lebrec, D.4    Burroughs, A.K.5    Morabito, A.6
  • 46
    • 0033403318 scopus 로고    scopus 로고
    • Pharmacological treatment of portal hypertension: An evidence-based approach
    • D'Amico G, Pagliaro L, Bosch J. Pharmacological treatment of portal hypertension: An evidence-based approach. Semin Liver Dis 1999;19:475-505
    • (1999) Semin Liver Dis , vol.19 , pp. 475-505
    • D'Amico, G.1    Pagliaro, L.2    Bosch, J.3
  • 47
    • 0033765377 scopus 로고    scopus 로고
    • The hemodynamic response to medical treatment of portal hypertension as a predictor of clinical effectiveness in the primary prophylaxis of variceal bleeding in cirrhosis
    • doi: 10.1053/jhep.2000.19322
    • Merkel C, Bolognesi M, Sacerdoti D, et al. The hemodynamic response to medical treatment of portal hypertension as a predictor of clinical effectiveness in the primary prophylaxis of variceal bleeding in cirrhosis. Hepatology 2000;32:930-934. doi: 10.1053/jhep.2000.19322
    • (2000) Hepatology , vol.32 , pp. 930-934
    • Merkel, C.1    Bolognesi, M.2    Sacerdoti, D.3
  • 48
    • 0036895678 scopus 로고    scopus 로고
    • A la carte or menu fixed: Improving pharmacologic therapy of portal hypertension
    • Bosch J. A la carte or menu fixed: Improving pharmacologic therapy of portal hypertension. Hepatology 2002;36:1330-1332
    • (2002) Hepatology , vol.36 , pp. 1330-1332
    • Bosch, J.1
  • 49
    • 0028790232 scopus 로고
    • Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis
    • doi: 10.1016/S0140-6736(95)91740-3
    • Feu F, Garcia-Pagan JC, Bosch J, Luca A, Teres J, Escorsell A, et al. Relation between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis. Lancet 1995;346:1056-1059. doi: 10.1016/S0140-6736(95)91740-3
    • (1995) Lancet , vol.346 , pp. 1056-1059
    • Feu, F.1    Garcia-Pagan, J.C.2    Bosch, J.3    Luca, A.4    Teres, J.5    Escorsell, A.6
  • 50
    • 0030003919 scopus 로고    scopus 로고
    • Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal rebleeding
    • doi: 10.1056/NEJM199606203342502
    • Villanueva C, Balanzo J, Novella MT, Soriano G, Sainz S, Torras X, et al. Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal rebleeding. N Engl J Med 1996;334:1624-1629. doi: 10.1056/NEJM199606203342502
    • (1996) N Engl J Med , vol.334 , pp. 1624-1629
    • Villanueva, C.1    Balanzo, J.2    Novella, M.T.3    Soriano, G.4    Sainz, S.5    Torras, X.6
  • 51
    • 0036896603 scopus 로고    scopus 로고
    • "A la carte" treatment of portal hypertension: Adapting medical therapy to hemodynamic response for the prevention of bleeding
    • Bureau C, Peron JM, Alric L, Morales J, Sanchez J, Barange K, et al. "A la carte" treatment of portal hypertension: Adapting medical therapy to hemodynamic response for the prevention of bleeding. Hepatology 2002;36:1361-1366
    • (2002) Hepatology , vol.36 , pp. 1361-1366
    • Bureau, C.1    Peron, J.M.2    Alric, L.3    Morales, J.4    Sanchez, J.5    Barange, K.6
  • 52
    • 24344439597 scopus 로고    scopus 로고
    • Hemodynamic response to beta-blockers and prediction of clinical efficacy in the primary prophylaxis of variceal bleeding in patients with cirrhosis
    • abstract doi: 10.1016/S0270-9139(03)80334-8
    • Aracil C, Lopez-Balaguer JM, Monfort D, Piqueras M, Gonzalez B, Minana J, et al. Hemodynamic response to beta-blockers and prediction of clinical efficacy in the primary prophylaxis of variceal bleeding in patients with cirrhosis. Hepatology 2003;38:296A. abstract doi: 10.1016/ S0270-9139(03)80334-8
    • (2003) Hepatology , vol.38
    • Aracil, C.1    Lopez-Balaguer, J.M.2    Monfort, D.3    Piqueras, M.4    Gonzalez, B.5    Minana, J.6
  • 53
    • 0029893927 scopus 로고    scopus 로고
    • A randomized controlled trial of endoscopic variceal band ligation for primary prophylaxis of variceal bleeding
    • doi: 10.1097/00042737-199604000-00010
    • Sarin SK, Guptan RC, Jain AK, Sundaram KR. A randomized controlled trial of endoscopic variceal band ligation for primary prophylaxis of variceal bleeding. Eur J Gastroenterol Hepatol 1996;8:337-342. doi: 10.1097/ 00042737-199604000-00010
    • (1996) Eur J Gastroenterol Hepatol , vol.8 , pp. 337-342
    • Sarin, S.K.1    Guptan, R.C.2    Jain, A.K.3    Sundaram, K.R.4
  • 54
    • 1542619403 scopus 로고    scopus 로고
    • Endoscopic ligation vs. nadolol in the prevention of first variceal bleeding in patients with cirrhosis
    • doi: 10.1016/S0016-5107(03)02819-0
    • Lo GH, Chen WC, Chen MH, Lin CP, Lo CC, Hsu PI, et al. Endoscopic ligation vs. nadolol in the prevention of first variceal bleeding in patients with cirrhosis. Gastrointest Endosc 2004;59:333-338. doi: 10.1016/S0016-5107(03)02819-0
    • (2004) Gastrointest Endosc , vol.59 , pp. 333-338
    • Lo, G.H.1    Chen, W.C.2    Chen, M.H.3    Lin, C.P.4    Lo, C.C.5    Hsu, P.I.6
  • 55
    • 3042700818 scopus 로고    scopus 로고
    • Ligation versus propranolol for the primary prophylaxis of variceal bleeding in cirrhosis
    • doi: 10.1002/hep.20284
    • Schepke M, Kleber G, Nurnberg D, Willert J, Koch L, Veltzke-Schlieker W, et al. Ligation versus propranolol for the primary prophylaxis of variceal bleeding in cirrhosis. Hepatology 2004;40:65-72. doi: 10.1002/ hep.20284
    • (2004) Hepatology , vol.40 , pp. 65-72
    • Schepke, M.1    Kleber, G.2    Nurnberg, D.3    Willert, J.4    Koch, L.5    Veltzke-Schlieker, W.6
  • 56
    • 33645230748 scopus 로고    scopus 로고
    • Endoscopic variceal ligation versus propranolol in prophylaxis of first variceal bleeding in patients with cirrhosis
    • doi: 10.1111/j.1440-1746.2005.04071.x
    • Lay CS, Tsai YT, Lee FY, Lai YL, Yu CJ, Chen CB, et al. Endoscopic variceal ligation versus propranolol in prophylaxis of first variceal bleeding in patients with cirrhosis. J Gastroenterol Hepatol 2006;21:413-419. doi: 10.1111/j.1440-1746.2005.04071.x
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 413-419
    • Lay, C.S.1    Tsai, Y.T.2    Lee, F.Y.3    Lai, Y.L.4    Yu, C.J.5    Chen, C.B.6
  • 57
    • 17144412520 scopus 로고    scopus 로고
    • Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices
    • doi: 10.1053/j.gastro.2005.01.047
    • Jutabha R, Jensen DM, Martin P, Savides T, Han SH, Gornbein J. Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices. Gastroenterology 2005;128:870-881. doi: 10.1053/j.gastro.2005.01.047
    • (2005) Gastroenterology , vol.128 , pp. 870-881
    • Jutabha, R.1    Jensen, D.M.2    Martin, P.3    Savides, T.4    Han, S.H.5    Gornbein, J.6
  • 58
    • 0035083039 scopus 로고    scopus 로고
    • A meta-analysis of endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleeding
    • doi: 10.1053/jhep.2001.23054
    • Imperiale TF, Chalasani N. A meta-analysis of endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleeding. Hepatology 2001;33:802-807. doi: 10.1053/jhep.2001.23054
    • (2001) Hepatology , vol.33 , pp. 802-807
    • Imperiale, T.F.1    Chalasani, N.2
  • 59
    • 0031047355 scopus 로고    scopus 로고
    • Primary prophylaxis of variceal bleeding in cirrhosis: A cost-effectiveness analysis
    • doi: 10.1053/gast.1997.v112.pm9024301
    • Teran JC, Imperiale TF, Mullen KD, Tavill AS, McCullough AJ. Primary prophylaxis of variceal bleeding in cirrhosis: A cost-effectiveness analysis. Gastroenterology 1997;112:473-482. doi: 10.1053/ gast.1997.v112.pm9024301
    • (1997) Gastroenterology , vol.112 , pp. 473-482
    • Teran, J.C.1    Imperiale, T.F.2    Mullen, K.D.3    Tavill, A.S.4    McCullough, A.J.5
  • 60
    • 14244253315 scopus 로고    scopus 로고
    • Pantoprazole reduces the size of post banding ulcers after variceal band ligation: A randomized controlled trial
    • doi: 10.1002/hep.20593
    • Shaheen NJ, Stuart E, Scmidt SM, Mitchell K, Fried M, et al. Pantoprazole reduces the size of post banding ulcers after variceal band ligation: A randomized controlled trial. Hepatology 2005;41:588-594. doi: 10.1002/hep.20593
    • (2005) Hepatology , vol.41 , pp. 588-594
    • Shaheen, N.J.1    Stuart, E.2    Scmidt, S.M.3    Mitchell, K.4    Fried, M.5
  • 61
    • 27744492401 scopus 로고    scopus 로고
    • A randomized control trial of bi-monthly versus bi-weekly endoscopic variceal ligation of oesophageal varices
    • doi: 10.1111/j.1572-0241.2005.41864.x
    • Yoshida H, Mamada Y, Taniai N, Yamamoto K, Kawano Y, Mizuguchi Y, et al. A randomized control trial of bi-monthly versus bi-weekly endoscopic variceal ligation of oesophageal varices. Am J Gastroenterol 2005;100(9):2005-2009. doi: 10.1111/j.1572-0241.2005.41864.x
    • (2005) Am J Gastroenterol , vol.100 , Issue.9 , pp. 2005-2009
    • Yoshida, H.1    Mamada, Y.2    Taniai, N.3    Yamamoto, K.4    Kawano, Y.5    Mizuguchi, Y.6
  • 62
    • 33644794426 scopus 로고    scopus 로고
    • Endoscopy critics vs endoscopy enthusiasts for primary prophylaxis of variceal bleeding
    • doi: 10.1002/hep.21026
    • De Franchis R. Endoscopy critics vs endoscopy enthusiasts for primary prophylaxis of variceal bleeding. Hepatology 2006;43:24-26. doi: 10.1002/ hep.21026
    • (2006) Hepatology , vol.43 , pp. 24-26
    • De Franchis, R.1
  • 63
    • 0001211870 scopus 로고    scopus 로고
    • Prophylactic endoscopic variceal ligation (EVL) with multiple band ligator for esophageal varices
    • abstract
    • Chen CY, Sheu MZ, Su SY. Prophylactic endoscopic variceal ligation (EVL) with multiple band ligator for esophageal varices. Gastroenterology 1998;114(Suppl):A1224. abstract
    • (1998) Gastroenterology , vol.114 , Issue.SUPPL.
    • Chen, C.Y.1    Sheu, M.Z.2    Su, S.Y.3
  • 64
    • 0032917565 scopus 로고    scopus 로고
    • Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleed: Preliminary report of a randomized controlled trial
    • doi: 10.1046/j.1440-1746.1999.01800.x
    • De BK, Ghoshal UK, Das T, Santra A, Biswas PK. Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleed: preliminary report of a randomized controlled trial. J Gastroenterol Hepatol 1999;14:220-224. doi: 10.1046/j.1440-1746.1999.01800.x
    • (1999) J Gastroenterol Hepatol , vol.14 , pp. 220-224
    • De, B.K.1    Ghoshal, U.K.2    Das, T.3    Santra, A.4    Biswas, P.K.5
  • 65
    • 0036731212 scopus 로고    scopus 로고
    • Primary prophylaxis of variceal haemorrhage: A randomized controlled trial comparing band ligation, propranolol, and isosorbide mononitrate
    • doi: 10.1053/gast.2002.35385
    • Lui HF, Stanley AJ, Forrest EH, Jalan R, Hislop WS, Mills PR, et al. Primary prophylaxis of variceal haemorrhage: A randomized controlled trial comparing band ligation, propranolol, and isosorbide mononitrate. Gastroenterology 2002;123:735-744. doi: 10.1053/gast.2002.35385
    • (2002) Gastroenterology , vol.123 , pp. 735-744
    • Lui, H.F.1    Stanley, A.J.2    Forrest, E.H.3    Jalan, R.4    Hislop, W.S.5    Mills, P.R.6
  • 66
    • 12144271585 scopus 로고    scopus 로고
    • A randomized controlled trial of β-blockers versus endoscopic band ligation for primary prophylaxis: A large sample size is required to show a difference in bleeding rates
    • doi: 10.1007/s10620-005-1619-8
    • Thuluvath PJ, Maheshwari A, Jagannath S, Arepally A. A randomized controlled trial of β-blockers versus endoscopic band ligation for primary prophylaxis: A large sample size is required to show a difference in bleeding rates. Dig Dis Sci 2005;50:407-410. doi: 10.1007/ s10620-005-1619-8
    • (2005) Dig Dis Sci , vol.50 , pp. 407-410
    • Thuluvath, P.J.1    Maheshwari, A.2    Jagannath, S.3    Arepally, A.4
  • 67
    • 26444508494 scopus 로고    scopus 로고
    • Endoscopic variceal ligation vs. propranolol for prevention of first variceal bleeding: A randomized controlled trial
    • doi: 10.1097/00042737-200510000-00016
    • Psilopoulos D, Galanis P, Goulas S, Papanikolaou IS, Elefsiniotis I, Liatsos C, et al. Endoscopic variceal ligation vs. propranolol for prevention of first variceal bleeding: A randomized controlled trial. Eur J Gastroenterol Hepatol 2005;17(10):1111-1117. doi: 10.1097/ 00042737-200510000-00016
    • (2005) Eur J Gastroenterol Hepatol , vol.17 , Issue.10 , pp. 1111-1117
    • Psilopoulos, D.1    Galanis, P.2    Goulas, S.3    Papanikolaou, I.S.4    Elefsiniotis, I.5    Liatsos, C.6
  • 68
    • 14644399798 scopus 로고    scopus 로고
    • Meta-analysis: Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleeding
    • doi: 10.1111/j.1365-2036.2005.02346.x
    • Khuroo MS, Khuroo NS, Farahat KLC, Khuroo YS, Sofi AA, Dahab ST. Meta-analysis: Endoscopic variceal ligation for primary prophylaxis of oesophageal variceal bleeding. Aliment Pharmacol Ther 2005;21:347-361. doi: 10.1111/j.1365-2036.2005.02346.x
    • (2005) Aliment Pharmacol Ther , vol.21 , pp. 347-361
    • Khuroo, M.S.1    Khuroo, N.S.2    Farahat, K.L.C.3    Khuroo, Y.S.4    Sofi, A.A.5    Dahab, S.T.6
  • 69
    • 17144419769 scopus 로고    scopus 로고
    • Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleeding
    • doi: 10.1111/j.1572-0241.2005.40468.x
    • Sarin SK, Wadhawan M, Agarwal SR, Tyagi P, Sharma BC. Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleeding. Am J Gastroenterol 2005;100:797-804. doi: 10.1111/j.1572-0241.2005.40468.x
    • (2005) Am J Gastroenterol , vol.100 , pp. 797-804
    • Sarin, S.K.1    Wadhawan, M.2    Agarwal, S.R.3    Tyagi, P.4    Sharma, B.C.5
  • 70
    • 0027301591 scopus 로고
    • Isosorbide-5-mononitrate versus propranolol in the prevention of first bleeding in cirrhosis
    • Angelico M, Carli L, Piat C, Gentile S, Rinaldi V, Bologna E, et al. Isosorbide-5-mononitrate versus propranolol in the prevention of first bleeding in cirrhosis. Gastroenterology 1993;104:1460-1465
    • (1993) Gastroenterology , vol.104 , pp. 1460-1465
    • Angelico, M.1    Carli, L.2    Piat, C.3    Gentile, S.4    Rinaldi, V.5    Bologna, E.6
  • 71
    • 0030775671 scopus 로고    scopus 로고
    • Beta-adrenergic blockers and nitrovasodilators for the treatment of portal hypertension: The good, the bad, the ugly
    • doi: 10.1053/gast.1997.v113.agast971131794
    • Groszmann RJ. Beta-adrenergic blockers and nitrovasodilators for the treatment of portal hypertension: The good, the bad, the ugly. Gastroenterology 1998;113:1794-1797. doi: 10.1053/ gast.1997.v113.agast971131794
    • (1998) Gastroenterology , vol.113 , pp. 1794-1797
    • Groszmann, R.J.1
  • 72
    • 0036708280 scopus 로고    scopus 로고
    • Nadolol is superior to isosorbide mononitrate for the prevention of the first variceal bleeding in cirrhotic patients with ascites
    • doi: 10.1016/S0168-8278(02)00174-5
    • Borroni G, Salerno F, Cazzaniga M, Bissoli F, Lorenzano E, Maggi A, et al. Nadolol is superior to isosorbide mononitrate for the prevention of the first variceal bleeding in cirrhotic patients with ascites. J Hepatol 2002;37:315-321. doi: 10.1016/S0168-8278(02)00174-5
    • (2002) J Hepatol , vol.37 , pp. 315-321
    • Borroni, G.1    Salerno, F.2    Cazzaniga, M.3    Bissoli, F.4    Lorenzano, E.5    Maggi, A.6
  • 73
    • 0030597496 scopus 로고    scopus 로고
    • Randomised trial of nadolol alone or with isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis
    • doi: 10.1016/S0140-6736(96)05406-2
    • Merkel C, Marin R, Enzo E, Donada C, Cavallarin G, Torboli P, et al. Randomised trial of nadolol alone or with isosorbide mononitrate for primary prophylaxis of variceal bleeding in cirrhosis. Lancet 1996;348:1677-1681. doi: 10.1016/S0140-6736(96)05406-2
    • (1996) Lancet , vol.348 , pp. 1677-1681
    • Merkel, C.1    Marin, R.2    Enzo, E.3    Donada, C.4    Cavallarin, G.5    Torboli, P.6
  • 74
    • 0037806032 scopus 로고    scopus 로고
    • Propranolol plus placebo versus propranolol plus isosorbide-5-mononitrate in the prevention of a first variceal bleed: A double-blind RCT
    • doi: 10.1053/jhep.2003.50211
    • Garcia-Pagan JC, Morillas R, Banares R, Albillos A, Villanueva C, Vila C, et al. Propranolol plus placebo versus propranolol plus isosorbide-5-mononitrate in the prevention of a first variceal bleed: A double-blind RCT. Hepatology 2003;37:1260-1266. doi: 10.1053/ jhep.2003.50211
    • (2003) Hepatology , vol.37 , pp. 1260-1266
    • Garcia-Pagan, J.C.1    Morillas, R.2    Banares, R.3    Albillos, A.4    Villanueva, C.5    Vila, C.6
  • 75
    • 0141681316 scopus 로고    scopus 로고
    • Isosorbide mononitrate with nadolol compared to nadolol alone for prevention of the first bleeding in cirrhosis. A double-blind placebo-controlled randomized trial
    • D'Amico G, Pasta L, Politi F, Vizzini G, Traina M, Caltagirone M, et al. Isosorbide mononitrate with nadolol compared to nadolol alone for prevention of the first bleeding in cirrhosis. A double-blind placebo-controlled randomized trial. Gastroenterol Int 2002;15:40-50
    • (2002) Gastroenterol Int , vol.15 , pp. 40-50
    • D'Amico, G.1    Pasta, L.2    Politi, F.3    Vizzini, G.4    Traina, M.5    Caltagirone, M.6
  • 76
    • 0026469124 scopus 로고
    • Prevalence, classification and natural history of gastric varices: A long-term follow-up study in 568 portal hypertension patients
    • doi: 10.1002/hep.1840160607
    • Sarin SK, Lahoti D, Saxena SP, Murthy NS, Makwana UK. Prevalence, classification and natural history of gastric varices: A long-term follow-up study in 568 portal hypertension patients. Hepatology 1992;16:1343-1349. doi: 10.1002/hep.1840160607
    • (1992) Hepatology , vol.16 , pp. 1343-1349
    • Sarin, S.K.1    Lahoti, D.2    Saxena, S.P.3    Murthy, N.S.4    Makwana, U.K.5
  • 78
    • 0023935479 scopus 로고
    • Gastric varices: A proposed classification leading to management
    • doi: 10.1002/bjs.1800750303
    • Hosking SW, Johnson AG. Gastric varices: A proposed classification leading to management. Br J Surg 1988;75:195-196. doi: 10.1002/ bjs.1800750303
    • (1988) Br J Surg , vol.75 , pp. 195-196
    • Hosking, S.W.1    Johnson, A.G.2
  • 79
    • 12644288352 scopus 로고    scopus 로고
    • Risk factors for hemorrhage from gastric fundal varices
    • doi: 10.1002/hep.510250209
    • Kim T, Shijo H, Kokawa H, Tokumitsu H, Kubara K, Ota K, et al. Risk factors for hemorrhage from gastric fundal varices. Hepatology 1997;25:307-312. doi: 10.1002/hep.510250209
    • (1997) Hepatology , vol.25 , pp. 307-312
    • Kim, T.1    Shijo, H.2    Kokawa, H.3    Tokumitsu, H.4    Kubara, K.5    Ota, K.6
  • 81
    • 0036051104 scopus 로고    scopus 로고
    • Pathology of fundic varices of the stomach and rupture
    • doi: 10.1046/j.1440-1746.2002.02855.x
    • Arakawa M, Masuzaki T, Okuda K. Pathology of fundic varices of the stomach and rupture. J Gastroenterol Hepatol 2002;17:1064-1069. doi: 10.1046/j.1440-1746.2002.02855.x
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 1064-1069
    • Arakawa, M.1    Masuzaki, T.2    Okuda, K.3
  • 82
    • 0029134073 scopus 로고
    • The treatment of portal hypertension: A meta-analytic review
    • D'Amico G, Pagliaro L, Bosch J. The treatment of portal hypertension: A meta-analytic review. Hepatology 1995;22:332-354
    • (1995) Hepatology , vol.22 , pp. 332-354
    • D'Amico, G.1    Pagliaro, L.2    Bosch, J.3
  • 83
    • 0024350019 scopus 로고
    • Successful endoscopic obturation of gastric varices with butyl cyanoacrylate
    • doi: 10.1002/hep.1840100415
    • Ramond MJ, Valla D, Mosnier JF, Degott C, Bernuau J, Rueff B, et al. Successful endoscopic obturation of gastric varices with butyl cyanoacrylate. Hepatology 1989;10:488-493. doi: 10.1002/hep.1840100415
    • (1989) Hepatology , vol.10 , pp. 488-493
    • Ramond, M.J.1    Valla, D.2    Mosnier, J.F.3    Degott, C.4    Bernuau, J.5    Rueff, B.6
  • 84
    • 0029088430 scopus 로고
    • Ethanolamine oleate versus butyl cyanoacrylate for bleeding gastric varices: A nonrandomized study
    • Oho K, Iwao T, Sumino M, Toyonaga A, Tanikawa K. Ethanolamine oleate versus butyl cyanoacrylate for bleeding gastric varices: A nonrandomized study. Endoscopy 1995;27:349-354
    • (1995) Endoscopy , vol.27 , pp. 349-354
    • Oho, K.1    Iwao, T.2    Sumino, M.3    Toyonaga, A.4    Tanikawa, K.5
  • 85
    • 0036123739 scopus 로고    scopus 로고
    • A randomized controlled trial of cyanoacrylate versus alcohol injection in patients with isolated fundic varices
    • doi: 10.1111/j.1572-0241.2002.05622.x
    • Sarin SK, Jain AK, Jain M, Gupta R. A randomized controlled trial of cyanoacrylate versus alcohol injection in patients with isolated fundic varices. Am J Gastroenterol 2002;97:1010-1015. doi: 10.1111/ j.1572-0241.2002.05622.x
    • (2002) Am J Gastroenterol , vol.97 , pp. 1010-1015
    • Sarin, S.K.1    Jain, A.K.2    Jain, M.3    Gupta, R.4
  • 86
    • 1842591036 scopus 로고    scopus 로고
    • A pilot study of 2-octyl-cyanoacrylate injection for treatment of gastric fundal varices in humans
    • doi: 10.1016/S0016-5107(03)02865-7
    • Rengstorff DS, Binmoeller KF. A pilot study of 2-octyl-cyanoacrylate injection for treatment of gastric fundal varices in humans. Gastrointest Endosc 2004;59:553-558. doi: 10.1016/S0016-5107(03)02865-7
    • (2004) Gastrointest Endosc , vol.59 , pp. 553-558
    • Rengstorff, D.S.1    Binmoeller, K.F.2
  • 87
    • 0031763191 scopus 로고    scopus 로고
    • Pulmonary, cerebral and coronary emboli during bucrylate injection of bleeding fundic varices
    • Roesch W, Rexroth G. Pulmonary, cerebral and coronary emboli during bucrylate injection of bleeding fundic varices. Endoscopy 1998;30:S89-S90
    • (1998) Endoscopy , vol.30
    • Roesch, W.1    Rexroth, G.2
  • 88
    • 0022542418 scopus 로고
    • Cerebrovascular accidents after endoscopic obturation of oesophageal varices with isobutyl-2-cyanoacrylate in 2 patients
    • See A, Florent C, Lamy P, Levy VG, Bouvry M. Cerebrovascular accidents after endoscopic obturation of oesophageal varices with isobutyl-2-cyanoacrylate in 2 patients. Gastroenterol Clin Biol 1986;10:604-607
    • (1986) Gastroenterol Clin Biol , vol.10 , pp. 604-607
    • See, A.1    Florent, C.2    Lamy, P.3    Levy, V.G.4    Bouvry, M.5
  • 89
    • 0029976161 scopus 로고    scopus 로고
    • Treatment of gastric fundal varices by balloon-occluded retrograde transvenous obliteration
    • doi: 10.1111/j.1440-1746.1996.tb00010.x
    • Kanagawa H, Mima H, Kouyama H, Gotoh K, Uchida T, Okuda K. Treatment of gastric fundal varices by balloon-occluded retrograde transvenous obliteration. J Gastroenterol Hepatol 1996;11:51-58. doi: 10.1111/ j.1440-1746.1996.tb00010.x
    • (1996) J Gastroenterol Hepatol , vol.11 , pp. 51-58
    • Kanagawa, H.1    Mima, H.2    Kouyama, H.3    Gotoh, K.4    Uchida, T.5    Okuda, K.6
  • 90
    • 0033053108 scopus 로고    scopus 로고
    • Treatment of gastric fundal varices by balloon endoscopic sclerotherapy
    • doi: 10.1016/S0016-5107(99)70459-1
    • Hamamoto N, Matsumoto A, Nomura T, Kayazawa M, Hirata I, Morikawa H, et al. Treatment of gastric fundal varices by balloon endoscopic sclerotherapy. Gastrointest Endosc 1999;49:115-118. doi: 10.1016/ S0016-5107(99)70459-1
    • (1999) Gastrointest Endosc , vol.49 , pp. 115-118
    • Hamamoto, N.1    Matsumoto, A.2    Nomura, T.3    Kayazawa, M.4    Hirata, I.5    Morikawa, H.6
  • 91
    • 0036780981 scopus 로고    scopus 로고
    • Efficacy and safety of balloon-occluded endoscopic injection for sclerotherapy as a prophylactic treatment for high-risk gastric varices: A prospective, randomized, comparative clinical trial
    • doi: 10.1016/S0016-5107(02)70437-9
    • Shiba M, Higuchi K, Nakamura K, Itani A, Kuga T, Okazaki H, et al. Efficacy and safety of balloon-occluded endoscopic injection for sclerotherapy as a prophylactic treatment for high-risk gastric varices: a prospective, randomized, comparative clinical trial. Gastrointest Endosc 2002;56:522-528. doi: 10.1016/S0016-5107(02)70437-9
    • (2002) Gastrointest Endosc , vol.56 , pp. 522-528
    • Shiba, M.1    Higuchi, K.2    Nakamura, K.3    Itani, A.4    Kuga, T.5    Okazaki, H.6
  • 92
    • 0032810322 scopus 로고    scopus 로고
    • Balloon endoscopic sclerotherapy, a novel treatment for high-risk gastric fundal varices: A pilot study
    • doi: 10.1053/gast.1999.0029900515
    • Matsumoto A, Hamamoto N, Kayazawa M. Balloon endoscopic sclerotherapy, a novel treatment for high-risk gastric fundal varices: A pilot study. Gastroenterology 1999;117:515-516. doi: 10.1053/gast.1999.0029900515
    • (1999) Gastroenterology , vol.117 , pp. 515-516
    • Matsumoto, A.1    Hamamoto, N.2    Kayazawa, M.3
  • 93
    • 0035104581 scopus 로고    scopus 로고
    • Long-term results of balloon occluded retrograde transvenous obliteration for the treatment of gastric varices and hepatic encephalopathy
    • doi: 10.1016/S1051-0443(07)61912-5
    • Fukuda T, Hirota S, Sugimura K. Long-term results of balloon occluded retrograde transvenous obliteration for the treatment of gastric varices and hepatic encephalopathy. J Vasc Interv Radiol 2001;12:327-336. doi: 10.1016/S1051-0443(07)61912-5
    • (2001) J Vasc Interv Radiol , vol.12 , pp. 327-336
    • Fukuda, T.1    Hirota, S.2    Sugimura, K.3
  • 94
    • 38449094157 scopus 로고    scopus 로고
    • Balloon-occluded retrograde transvenous obliteration of gastric varices: Outcomes and complications in 49 patients
    • doi: 10.2214/AJR.07.2266
    • Cho SK, Shin SW, Lee IH, Do YS, Choo SW, Park KB, et al. Balloon-occluded retrograde transvenous obliteration of gastric varices: outcomes and complications in 49 patients. AJR Am J Roentgenol 2007;189(6):W365-W372. doi: 10.2214/AJR.07.2266
    • (2007) AJR Am J Roentgenol , vol.189 , Issue.6
    • Cho, S.K.1    Shin, S.W.2    Lee, I.H.3    Do, Y.S.4    Choo, S.W.5    Park, K.B.6
  • 95
    • 33745810935 scopus 로고    scopus 로고
    • Efficacy of balloon-occluded retrograde transvenous obliteration, percutaneous transhepatic obliteration and combined techniques for the management of gastric fundal varices
    • Arai H, Abe T, Takagi H, Mori M. Efficacy of balloon-occluded retrograde transvenous obliteration, percutaneous transhepatic obliteration and combined techniques for the management of gastric fundal varices. World J Gastroenterol 2006;12(24):3866-3873
    • (2006) World J Gastroenterol , vol.12 , Issue.24 , pp. 3866-3873
    • Arai, H.1    Abe, T.2    Takagi, H.3    Mori, M.4
  • 96
    • 0028537558 scopus 로고
    • Diagnostic upper GI endoscopy for hematemesis in children: Experience from a pediatric gastroenterology centre in north India
    • doi: 10.1007/BF02751973
    • Mittal SK, Kalra KK, Aggarwal V. Diagnostic upper GI endoscopy for hematemesis in children: Experience from a pediatric gastroenterology centre in north India. Indian J Pediatr 1994;61:651-654. doi: 10.1007/ BF02751973
    • (1994) Indian J Pediatr , vol.61 , pp. 651-654
    • Mittal, S.K.1    Kalra, K.K.2    Aggarwal, V.3
  • 98
    • 0018383478 scopus 로고
    • Upper gastrointestinal bleeding in children and adolescents
    • Cox K, Ament ME. Upper gastrointestinal bleeding in children and adolescents. Pediatrics 1979;63:408-413
    • (1979) Pediatrics , vol.63 , pp. 408-413
    • Cox, K.1    Ament, M.E.2
  • 99
    • 0023993172 scopus 로고
    • Extrahepatic portal venous obstruction
    • doi: 10.1136/gut.29.4.554
    • Dilawari JB, Chawla YK. Extrahepatic portal venous obstruction. Gut 1988;29:554-555. doi: 10.1136/gut.29.4.554
    • (1988) Gut , vol.29 , pp. 554-555
    • Dilawari, J.B.1    Chawla, Y.K.2
  • 101
    • 0021324776 scopus 로고
    • Management of esophageal varices in children by injection sclerotherapy
    • Howard ER, Stamatakis JD, Mowat AP. Management of esophageal varices in children by injection sclerotherapy. J Pediatr Surg 1984;19:2-5
    • (1984) J Pediatr Surg , vol.19 , pp. 2-5
    • Howard, E.R.1    Stamatakis, J.D.2    Mowat, A.P.3
  • 102
    • 0023909510 scopus 로고
    • Assessment of injection sclerotherapy in the management of 152 children with esophageal varices
    • Howard ER, Stringer MD, Mowat AP. Assessment of injection sclerotherapy in the management of 152 children with esophageal varices. Br J Surg 1988;75:404-408
    • (1988) Br J Surg , vol.75 , pp. 404-408
    • Howard, E.R.1    Stringer, M.D.2    Mowat, A.P.3
  • 103
    • 0034014753 scopus 로고    scopus 로고
    • Prophylactic sclerotherapy in children with esophageal varices: Long-term results of a controlled prospective randomized trial
    • Goncalves MEP, Cardoso SR, Maksoud JG. Prophylactic sclerotherapy in children with esophageal varices: Long-term results of a controlled prospective randomized trial. J Pediatr Surg 2000;35:401-405
    • (2000) J Pediatr Surg , vol.35 , pp. 401-405
    • Goncalves, M.E.P.1    Cardoso, S.R.2    Maksoud, J.G.3
  • 104
    • 0032106012 scopus 로고    scopus 로고
    • Portal hypertension in north Indian children
    • Arora NK, Lodha R, Gulati S, et al. Portal hypertension in north Indian children. Indian J Pediatr 1998;65:585-591
    • (1998) Indian J Pediatr , vol.65 , pp. 585-591
    • Arora, N.K.1    Lodha, R.2    Gulati, S.3
  • 105
    • 0037999952 scopus 로고    scopus 로고
    • Endoscopic ligation of esophageal varices for prophylaxis of first bleeding in children and adolescents with portal hypertension: Preliminary results of a prospective study
    • Celinska-Cedro D, Teisseyre M, Woynarowski M, et al. Endoscopic ligation of esophageal varices for prophylaxis of first bleeding in children and adolescents with portal hypertension: Preliminary results of a prospective study. J Pediatr Surg 2003;38:1008-1011
    • (2003) J Pediatr Surg , vol.38 , pp. 1008-1011
    • Celinska-Cedro, D.1    Teisseyre, M.2    Woynarowski, M.3
  • 106
    • 0033511314 scopus 로고    scopus 로고
    • Propanolol in prevention of portal hypertensive hemorrhage in children: A pilot study
    • Shashidhar H, Langhans N, Grand RJ. Propanolol in prevention of portal hypertensive hemorrhage in children: A pilot study. J Pediatr Gastroenterol Nutr 1999;29:12-17
    • (1999) J Pediatr Gastroenterol Nutr , vol.29 , pp. 12-17
    • Shashidhar, H.1    Langhans, N.2    Grand, R.J.3


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