Live single-cell video-mass spectrometry for cellular and subcellular molecular detection and cell classification

Journal of Mass Spectrometry

Volumn 43, Issue 12, 2008, Pages 1692-1700

  Mizuno, Hajime ^a   Tsuyama, Naohiro ^a   Harada, Takanori ^a   Masujima, Tsutomu ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Cell typing; Live single cell mass spectrometry; Nano ESI; Organelle; Principal components analysis; Single cell; t test; Video mass spectrometry

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; CELLS; ELECTROSPRAY IONIZATION; MAMMALS; MASS SPECTROMETRY;

CELL TYPING; LIVE SINGLE-CELL MASS SPECTROMETRY; NANO-ESI; ORGANELLE; PRINCIPAL COMPONENTS ANALYSIS; SINGLE CELLS; T-TESTS; VIDEO-MASS SPECTROMETRY;

PRINCIPAL COMPONENT ANALYSIS;

ARTICLE; CELL LINE; ELECTROSPRAY; MASS SPECTROMETRY; MAST CELL; MULTIVARIATE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; STUDENT T TEST;

MAMMALIA;

EID: 57149112146     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1460     Document Type: Article

References (35)

1. Alberts B, Johnson A, Walter P, Lewis J, Raff M, Roberts K. Molecular Biology of the Cell, 5th ed. Garland Science: London, 2008.
2. Masujima T. Visualized single cell dynamics and analysis of molecular tricks. Analytica Chimica Acta 1999; 400: 33.
3. Rizzuto R, Carrington W, Tuft RA. Digital imaging microscopy of living cells. Trends in Cell Biology 1998; 8: 288.
4. Tsien RY. Fluorescent indicators of ion concentrations. Methods in Cell Biology 1989; 30: 127.
5. Caprioli RM, Farmer TB, Gile J. Molecular imaging of biological samples: localization of peptides and proteins using MALDITOF MS. Analytical Chemistry 1997; 69: 4751.
6. Garden RW, Sweedler JV. Heterogeneity within MALDI samples as revealed by mass spectrometric imaging. Analytical Chemistry 2000; 72: 30.
7. Koomen JM, Stoeckli M, Caprioli RM. Mapping of surrogate markers of cellular components and structures using laser desorption/ionization mass spectrometry. Journal of Mass Spectrometry 2000; 35: 258.
8. Stoeckli M, Chaurand P, Hallahan DE, Caprioli RM. Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues. Nature Medicine 2001; 7: 493.
9. Todd PJ, Schaaff TG, Chaurand P, Caprioli RM. Organic ion imaging of biological tissue with secondary ion mass spectrometry and matrix-assisted laser desorption/ionization. Journal of Mass Spectrometry 2001; 36: 355.
10. Kruse RA, Rubakhin SS, Romanova EV, Bohn PW, Sweedler JV. Direct assay of Aplysia tissues and cells with laser desorption/ionization mass spectrometry on porous silicon. Journal of Mass Spectrometry 2001; 36: 1317.
11. McDonnell LA, Heeren RM. Imaging mass spectrometry. Mass Spectrometry Reviews 2007; 26: 606.
12. Wiseman JM, Ifa DR, Song Q, Cooks RG. Tissue imaging at atmospheric pressure using desorption electrospray ionization (DESI) mass spectrometry. Angewandte Chemie International Edition in English 2006; 45: 7188.
13. Wiseman JM, Ifa DR, Venter A, Cooks RG. Ambient molecular imaging by desorption electrospray ionization mass spectrometry. Nature Protocols 2008; 3: 517.
14. Clarke NJ, Rindgen D, Korfmacher WA, Cox KA. Systematic LC/MS metabolite identification in drug discovery. Analytical Chemistry 2001; 73: 430A.
15. Breitling R, Pitt AR, Barrett MP. Precision mapping of the metabolome. Trends in Biotechnology 2006; 24: 543.
16. Aebersold R, Mann M. Mass spectrometry-based proteomics. Nature 2003; 422: 198.
17. vanVeelen PA, Jiminez CR, Li KW, Wildering WC, Geraerts PM, Tjaden UR, van der Greef J. Direct peptide profiling of single neurons by matrix-assisted laser-desorption ionization mass-spectrometry. Organic Mass Spectrometry 1993; 28: 1542.
18. Jimenez CR, van Veelen PA, Li KW, Wildering WC, Geraerts WP, Tjaden UR, van der Greef J. Neuropeptide expression and processing as revealed by direct matrix-assisted laser desorption ionizationmass spectrometry of single neurons. Journal of Neurochemistry 1994; 62: 404.
19. Shimizu M, Levi-Schaffer F, Ojima N, Shinagaki T, Masujima T. A single-cell matrix-assisted laser desorption/ionization time-of-flight mass-spectroscopic assay of the cell-maturation process. Analytical Sciences 2002; 18: 107.
20. Rubakhin SS, Sweedler JV. Characterizing peptides in individual mammalian cells using mass spectrometry. Nature Protocols 2007; 2: 1987.
21. Masujima T, Tsuyama N, Hasegawa T. Videovisualization of dynamic cell responses and its molecular analysis for nanomedicine. Nanomedicine 2006; 1: 331.
22. Sirikatitham A, Yamamoto T, Shimizu M, Hasegawa T, Tsuyama N, Masujima T. Resin-packed nanoelectrospray in combination with video andmass spectrometry for the direct and real-time molecular analysis of mast cells. Rapid Communications in Mass Spectrometry 2007; 21: 385.
23. Tsuyama N, Mizuno H, Tokunaga E, Masujima T. Live single-cell molecular analysis by video-mass spectrometry. Analytical Sciences 2008; 24: 559.
24. Takahashi N, Tsuyama N, Sasaki K, Kodaira M, Satoh Y, Kodama Y, Sugita K, Katayama H. Segmental copy-number variation observed in Japanese by array-CGH. Annals of Human Genetics 2008; 72: 193.
25. Eccleston E, Leonard BJ, Lowe JS, Welford HJ. Basophilic leukaemia in the albino rat and a demonstration of the basopoietin. Nature: New Biology 1973; 244: 73.
26. Kotani S, Murofushi H, Maekawa S, Aizawa H, Kaji K, Sakai H. Identification of the 190 kD microtubule-associated protein in cultured fibroblasts and its association with interphase and mitotic microtubules. Cell Structure and Function 1987; 12: 1.
27. Aden DP, Fogel A, Plotkin S, Damjanov I, Knowles BB. Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature 1979; 282: 615.
28. Kochevar J. Blockage of autonomous growth of ACHN cells by anti-renal cell carcinoma monoclonal antibody 5F4. Cancer Research 1990; 50: 2968.
29. Fogh J, Wright WC, Loveless JD. Absence of HeLa cell contamination in 169 cell lines derived from human tumors. Journal of the National Cancer Institute 1977; 58: 209.
30. McBurney MW, Rogers BJ. Isolation of male embryonal carcinoma cells and their chromosome replication patterns. Developmental Biology 1982; 89: 503.
31. Todaro GJ, Green H. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. Journal of Cell Biology 1963; 17: 299.
32. Gao J, Opiteck GJ, Friedrichs MS, Dongre AR, Hefta SA. Changes in the protein expression of yeast as a function of carbon source. Journal of Proteome Research 2003; 2: 643.
33. Fiehn O, Kopka J, Dörmann P, Altmann T, Trethewey RN, Willmitzer L. Metabolite profiling for plant functional genomics. Nature Biotechnology 2000; 18: 1157.
34. Tanaka S, Nemoto K, Yamamura E, Ichikawa A. Intracellular localization of the 74- and 53-kDa forms of L-histidine decarboxylase in a rat basophilic/mast cell line, RBL-2H3. Journal of Biological Chemistry 1998; 273: 8177.
35. Wellner VP, Sekura R, Meister A, Larsson A. Glutathione synthetase deficiency, an inborn error of metabolism involving the γ glutamyl cycle in patients with 5-oxoprolinuria (pyroglutamic aciduria). Proceedings of the National Academy of Sciences of the United States of America 1974; 71: 2505.