Effect of presumptive co-trimoxazole prophylaxis on pneumococcal colonization rates, seroepidemiology and antibiotic resistance in Zambian infants: A longitudinal cohort study

Bulletin of the World Health Organization

Volumn 86, Issue 12, 2008, Pages 929-938

  Gill, Christopher J ^a,d   Mwanakasale, V ^b   Fox, M P ^b   Chilengi, R ^c   Tembo, M ^b   Nsofwa, M ^b   Chalwe, V ^b   Mwananyanda, L ^d   Mukwamataba, D ^b   Malilwe, B ^b   Champo, D ^b   Macleod, W B ^a   Theaa, D M ^a   Hamera, D H ^a  

^a BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^b TROPICAL DISEASES RESEARCH CENTRE   (Zambia)

^c African Malaria Network Trust AMANET   (Tanzania)

^d Zambia Emory HIV Research Project   (Zambia)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL; CLINDAMYCIN; COTRIMOXAZOLE; ERYTHROMYCIN; PENICILLIN G; PNEUMOCOCCUS VACCINE; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; BACTERIAL DISEASE; CHILD HEALTH; COHORT ANALYSIS; EPIDEMIOLOGY; HUMAN IMMUNODEFICIENCY VIRUS; VACCINE; WORLD HEALTH ORGANIZATION;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM DETECTION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; INFANT; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; NASOPHARYNX; PRENATAL EXPOSURE; SEROEPIDEMIOLOGY; SEROTYPE; STATISTICAL SIGNIFICANCE; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE; WORLD HEALTH ORGANIZATION; ZAMBIA;

ANTI-INFECTIVE AGENTS; ANTIBIOTIC PROPHYLAXIS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; LONGITUDINAL STUDIES; MALE; MICROBIAL SENSITIVITY TESTS; PNEUMOCOCCAL INFECTIONS; SEROEPIDEMIOLOGIC STUDIES; STREPTOCOCCUS PNEUMONIAE; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION; ZAMBIA;

STREPTOCOCCUS PNEUMONIAE;

EID: 57149105523     PISSN: 00429686     EISSN: 15640604     Source Type: Journal    
DOI: 10.2471/BLT.07.049668     Document Type: Article

References (33)

1. Guidelines on co-trimoxazole prophylaxis for HIV-related infections among children, adolescents and adults in resource-limited settings: recommendations for a public health approach. Geneva: WHO/UNAIDS; 2006.
2. UNAIDS/WHO hail consensus on use of co-trimoxazole for prevention of HIV-related infections in Africa, 2000 [Press release]. Geneva: WHO; 2000. Available from: http//who.int/inf-pr-2000/en/pr2000-23.html [accessed on 4 August 2008].
3. Guay LA, Musoke P, Fleming T, Bagenda D, Allen M, Nakabiito C, et al. Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial. Lancet 1999;354:795-802. PMID:10485720
4. Gill CJ, Sabin LL, Tham J, Hamer DH. Reconsidering empirical co-trimoxazole prophylaxis for infants exposed to HIV infection. Bull World Health Organ 2004;82:290-7. PMID:15259258
5. Porat N, Leibovitz E, Dagan R, Coman G, Sfartz S, Peled N, et al. Molecular typing of Streptococcus pneumoniae in northeastern Romania: unique clones of S. pneumoniae isolated from children hospitalized for infections and from healthy and human immunodeficiency virus-infected children in the community. J Infect Dis 2000;181:966-74. PMID:10720519 doi:10.1086/315316
6. Leibovitz E, Dragomir C, Sfartz S, Porat N, Yagupsky P, Jica S, et al. Nasopharyngeal carriage of multidrug-resistant Streptococcus pneumoniae in institutionalized HIV-infected and HIV-negative children in northeastern Romania. Int J Infect Dis 1999;3:211-5. PMID:10575151 doi:10.1016/S1201-9712(99)90027-9
7. Tarasi A, Chong Y, Lee K, Tomasz A. Spread of the serotype 23F multidrug-resistant Streptococcus pneumoniae clone to South Korea. Microb Drug Resist 1997;3:105-9. PMID:9109101
8. Barnes DM, Whittier S, Gilligan PH, Soares S, Henderson FW, Tomasz A, et al. Transmission of multidrug-resistant serotype 23F Streptococcus pneumoniae in group day care: evidence suggesting capsular transformation of the resistant strain in vivo. J Infect Dis 1995;171:890-6. PMID:7706816
9. Kellner JD, McGeer A, Cetron MS, Low DE, Butler JC, Matlow A, et al. The use of Streptococcus pneumoniae nasopharyngeal isolates from healthy children to predict features of invasive disease. Pediatr Infect Dis J 1998;17:279-86. PMID:9576381 doi:10.1097/00006454-199804000-00004
10. Scott JA, Hall AJ, Hannington A, Edwards R, Mwarumba S, Lowe B, et al. Serotype distribution and prevalence of resistance to benzylpenicillin in three representative populations of Streptococcus pneumoniae isolates from the coast of Kenya. Clin Infect Dis 1998;27:1442-50. PMID:9868658 doi:10.1086/515013
11. Rusen ID, Fraser-Roberts L, Slaney L, Ombette J, Lovgren M, Datta P, et al. Nasopharyngeal pneumococcal colonization among Kenyan children: antibiotic resistance, strain types and associations with human immunodeficiency virus type 1 infection. Pediatr Infect Dis J 1997;16:656-62. PMID:9239769 doi:10.1097/00006454-199707000-00007
12. Gratten M, Nimmo G, Carlisle J, Schooneveldt J, Seneviratne E, Kelly R, et al. Emergence of further serotypes of multiple drug-resistant Streptococcus pneumoniae in Queensland. Commun Dis Intell 1997;21:133-6. PMID:9170700
13. McKenna SL, Muyinda GK, Roth D, Mwali M, Ng'andu N, Myrick A, et al. Rapid HIV testing and counseling for voluntary testing centers in Africa. AIDS 1997;11 Suppl 1;S103-10. PMID:9376093
14. Phili R, Vardas E. Evaluation of a rapid human immunodeficiency virus test at two community clinics in Kwazulu-Natal. S Afr Med J 2002;92:818-21. PMID:12432808
15. O'Brien KL, Nohynek H. Report from a WHO Working Group: standard method for detecting upper respiratory carriage of Streptococcus pneumoniae. Pediatr Infect Dis J 2003;22:e1-11. PMID:12586987 doi:10.1097/00006454-200302000- 00010
16. Converse GM 3rd, Dillon HC Jr. Epidemiological studies of Streptococcus pneumoniae in infants: methods of isolating pneumococci. J Clin Microbiol 1977;5:293-6. PMID:16032
17. Sondag JE, Morgens RK, Hoppe JE, Marr JJ. Detection of pneumococci in respiratory secretions: clinical evaluation of gentamicin blood agar. J Clin Microbiol 1977;5:397-400. PMID:16034
18. Performance standards for antimicrobial susceptibility testing: 9th informational supplement [NCCLS document M100-S9]. Villanova, PA: National Committee for Clinical Laboratory Standards; 1991.
19. Pikis A, Campos JM, Rodriguez WJ, Keith JM. Optochin resistance in Streptococcus pneumoniae: mechanism, significance, and clinical implications. J Infect Dis 2001;184:582-90. PMID:11474432 doi:10.1086/322803
20. Kacou-N'Douba A, Bouzid SA, Guessennd KN, Kouassi-M'Bengue AA, Faye-Kette AY, Dosso M. Antimicrobial resistance of nasopharyngeal isolates of Streptococcus pneumoniae in healthy carriers: report of a study in 5-year-olds in Marcory, Abidjan, Cote d'Ivoire. Ann Trop Paediatr 2001;21:149-54. PMID:11471259
21. Giger O, Mortensen JE, Clark RB, Evangelista A. Comparison of five different susceptibility test methods for detecting antimicrobial agent resistance among Haemophilus influenzae isolates. Diagn Microbiol Infect Dis 1996;24:145-53. PMID:8724400 doi:10.1016/0732-8893(96)00026-0
22. Ramsey FL, Schafer DW. The statistical sleuth - a course in methods of data analysis. Belmont, CA: Duxbury Press; 1997.
23. Feikin DR, Dowell SF, Nwanyanwu OC, Klugman KP, Kazembe PN, Barat LM, et al. Increased carriage of trimethoprim/sulfamethoxazole-resistant Streptococcus pneumoniae in Malawian children after treatment for malaria with sulfadoxine/pyrimethamine. J Infect Dis 2000;181:1501-5. PMID:10762585 doi:10.1086/315382
24. Yomo A, Subramanyam VR, Fudzulani R, Kamanga H, Graham SM, Broadhead RL, et al. Carriage of penicillin-resistant pneumococci in Malawian children. Ann Trop Paediatr 1997;17:239-43. PMID:9425380
25. Gray BM, Converse GM 3rd, Dillon HC Jr. Epidemiologic studies of Streptococcus pneumoniae in infants: acquisition, carriage, and infection during the first 24 months of life. J Infect Dis 1980;142:923-33. PMID:7462701
26. Gray BM, Dillon HC Jr. Clinical and epidemiologic studies of pneumococcal infection in children. Pediatr Infect Dis 1986;5:201-7. PMID:3952010 doi:10.1097/00006454-198605010-00011
27. Courvalin P, Carlier C. Transposable multiple antibiotic resistance in Streptococcus pneumoniae. Mol Gen Genet 1986;205:291-7. PMID:3027505 doi:10.1007/BF00430441
28. Puopolo KM, Klinzing DC, Lin MP, Yesucevitz DL, Cieslewicz MJ. A composite transposon associated with erythromycin and clindamycin resistance in group B Streptococcus. J Med Microbiol 2007;56:947-55. PMID:17577061 doi:10.1099/jmm.0.47131-0
29. Montanari MP, Cochetti I, Mingoia M, Varaldo PE. Phenotypic and molecular characterization of tetracycline- and erythromycin-resistant strains of Streptococcus pneumoniae. Antimicrob Agents Chemother 2003;47:2236-41. PMID:12821474 doi:10.1128/AAC.47.7.2236-2241.2003
30. Abdel-Haq N, Abuhammour W, Asmar B, Thomas R, Dabbagh S, Gonzalez R. Nasopharyngeal colonization with Streptococcus pneumoniae in children receiving trimethoprim-sulfamethoxazole prophylaxis. Pediatr Infect Dis J 1999;18:647-9. PMID:10440445 doi:10.1097/00006454-199907000-00017
31. Simell B, Kilpi TM, Käyhty H. Pneumococcal carriage and otitis media induce salivary antibodies to pneumococcal capsular polysaccharides in children. J Infect Dis 2002;186:1106-14. PMID:12355361 doi:10.1086/344235
32. Zar HJ, Hanslo D, Tannenbaum E, Klein M, Argent A, Eley B, et al. Aetiology and outcome of pneumonia in human immunodeficiency virus-infected children hospitalized in South Africa. Acta Paediatr 2001;90:119-25. PMID:11236037 doi:10.1080/080352501300049163
33. Thera MA, Sehdev PS, Coulibaly D, Traore K, Garba MN, Cissoko Y, et al. Impact of trimethoprim-sulfamethoxazole prophylaxis on falciparum malaria infection and disease. J Infect Dis 2005;192:1823-9. PMID:16235184 doi:10.1086/498249