Knockout of the erythromycin biosynthetic cluster gene, eryBI, blocks isoflavone glucoside bioconversion during erythromycin fermentations in Aeromicrobium erythreum but not in Saccharopolyspora erythraea

Applied and Environmental Microbiology

Volumn 74, Issue 23, 2008, Pages 7383-7390

  Reeves, Andrew R ^a,b   Seshadri, Ramya ^a,c   Brikun, Igor A ^a,d   Cernota, William H ^a   Gonzalez, Melissa C ^a   Weber, J Mark ^a  

^a Fermalogic Inc   (United States)

^b Research Microbiologist   (United States)

^c Abbott Molecular Inc   (United States)

^d Euclid Biosciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; FERMENTATION; METABOLISM;

AGLYCONES; CLUSTER GENES; CO PRODUCTS; ERYTHROMYCIN FERMENTATIONS; ERYTHROMYCIN PRODUCTIONS; GLUCOSIDASE; GROWTH MEDIUMS; ISOFLAVONE; KNOCK OUTS; NUTRACEUTICAL COMPOUNDS; SACCHAROPOLYSPORA ERYTHRAEA; SOY FLOURS;

CARBOHYDRATES;

ERYTHROMYCIN; GLUCOSIDE; ISOFLAVONE DERIVATIVE;

BACTERIUM; BIOTRANSFORMATION; DRUG; ENZYME ACTIVITY; FERMENTATION; GENE EXPRESSION; METABOLISM;

AEROMICROBIUM ERYTHREUM; ARTICLE; BACTERIAL GENE; BACTERIAL METABOLISM; BIOTRANSFORMATION; FERMENTATION; KNOCKOUT GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; SACCHAROPOLYSPORA; STREPTOMYCES ERYTHRAEUS;

ACTINOMYCETALES; BACTERIAL PROTEINS; BIOTRANSFORMATION; ERYTHROMYCIN; GENE DELETION; ISOFLAVONES;

AEROMICROBIUM ERYTHREUM; SACCHAROPOLYSPORA ERYTHRAEA;

EID: 57149096873     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.01759-08     Document Type: Article

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