Posttreatment with the Ca2+-Mg2+-dependent endonuclease inhibitor aurintricarboxylic acid abolishes genotoxic agent-induced nuclear condensation and DNA fragmentation and decreases death of astrocytes

Journal of Neuroscience Research

Volumn 86, Issue 13, 2008, Pages 2925-2931

  Lu, Huafei ^a   Wei, Gangwei ^a   Wang, Dongmin ^a   Yung, Patrick ^a   Ying, Weihai ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Astrocyte; Ca2+ Mg2+ endonucleases; Cell death; DNA fragmentation; Nuclear condensation

Indexed keywords

ADENOSINE TRIPHOSPHATE; AURINTRICARBOXYLIC ACID; CALCIUM ION; DNA; ENDONUCLEASE; MAGNESIUM ION; METHYLNITRONITROSOGUANIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CELL NUCLEUS; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; ENZYME INHIBITION; GENOTOXICITY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION;

ANIMALS; APOPTOSIS; ASTROCYTES; AURINTRICARBOXYLIC ACID; CELL NUCLEUS; CELLS, CULTURED; DNA DAMAGE; DNA FRAGMENTATION; ENDONUCLEASES; ENZYME INHIBITORS; IMMUNOHISTOCHEMISTRY; METHYLNITRONITROSOGUANIDINE; MICE; NECROSIS; POLY(ADP-RIBOSE) POLYMERASES;

EID: 57049175874     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21733     Document Type: Article

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