Differential analysis of effect of high glucose level in the development of neuropathy in a tissue culture model of diabetes mellitus: Role of hyperosmolality

Experimental and Clinical Endocrinology and Diabetes

Volumn 116, Issue 10, 2008, Pages 582-591

  Ozturk G ^a   Erdogan E ^a   Ozturk M ^a   Cengiz, N ^a   Him, A ^a  

^a YUZUNCU YIL UNIVERSITY   (Turkey)

Author keywords

Diabetic neuropathy; Dorsal root ganglion; High glucose; Hyperosmolality; Mannitol

Indexed keywords

COLLAGEN GEL; GLUCOSE; MANNITOL;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CULTURE MEDIUM; DIABETES MELLITUS; DIABETIC NEUROPATHY; HYPEROSMOLALITY; MITOSIS RATE; MOUSE; NERVE CELL NECROSIS; NERVE FIBER GROWTH; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPINAL GANGLION; TISSUE CULTURE;

ANIMALS; APOPTOSIS; AXONS; CELL DEATH; CELL MOVEMENT; DIABETIC NEUROPATHIES; DISEASE MODELS, ANIMAL; GANGLIA, SPINAL; GLUCOSE; HYPERGLYCEMIA; IN SITU NICK-END LABELING; MANNITOL; MICE; NEURONS; PERIPHERAL NERVES; REGENERATION;

EID: 57049163061     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1065334     Document Type: Article

References (45)

1. Almhanna K, Wilkins PL, Bavis JR, Harwalkar S, Berti-Mattera LN. Hyperglycemia triggers abnormal signaling and proliferative responses in Schwann cells. Neurochem Res 2002; 27: 1341-1347
2. Bagnasco SM, Uchida S, Balaban RS, Kador PF, Burg MB. Induction of aldose reductase and sorbitol in renal inner medullary cells by elevated extracellular NaCl. Proc Natl Acad Sci USA 1987; 84: 1718-1720
3. Bhardwaj A, Harukuni I, Murphy SJ et al. Hypertonic saline worsens infarct volume after transient focal ischemia in rats. Stroke 2000; 31: 1694-1701
4. Bisby MA. Axonal transport of labeled protein and regeneration rate in nerves of streptozocin-diabetic rats. Exp Neurol 1980; 69: 74-84
5. Braaten JT. Hyperosmolar nonketotic diabetic coma: diagnosis and management. Geriatrics 1987; 42: 83-88,92
6. Burg MB. Role of aldose reductase and sorbitol in maintaining the medullary intracellular milieu. Kidney Int 1988; 33: 635-641
7. Busik JV, Hootman SR, Greenidge CA, Henry DN. Glucose-specific regulation of aldose reductase in capan-1 human pancreatic duct cells in vitro. J Clin Invest 1997; 100: 1685-1692
8. Chakrabarti S, Sima AA, Nakajima T, Yagihashi S, Greene DA. Aldose reductase in the BB rat: isolation, immunological identification and localization in the retina and peripheral nerve. Diabetologia 1987; 30: 244-251
9. Chung SS, Ho EC, Lam KS, Chung SK. Contribution of polyol pathway to diabetes-induced oxidative stress. J Am Soc Nephrol 2003; 14: S233-S236
10. Copp J, Wiley S, Ward MW, Geer P Van Der. Hypertonic shock inhibits growth factor receptor signaling, induces caspase 3 activation, and causes reversible fragmentation of the mitochondrial network. Am J Physiol Cell Physiol 2004
11. Ekstrom AR, Kanje M, Skottner A. Nerve regeneration and serum levels of insulin-like growth factor-I in rats with streptozotocin-induced insulin deficiency. Brain Res 1989; 496: 141-147
12. Faradji V, Sotelo J. Low serum levels of nerve growth factor in diabetic neuropathy. Acta Neurol Scand 1990; 81: 402-406
13. Flyvbjerg A, Orskov H. Diabetic angiopathy: new experimental and clinical aspects. Horm Metab Res 2005; 37 Suppl 1: 1-3
14. Fu SY, Gordon T. The cellular and molecular basis of peripheral nerve regeneration. Mol Neurobiol 1997; 14: 67-116
15. Fulop M, Rosenblatt A, Kreitzer SM, Gerstenhaber B. Hyperosmolar nature of diabetic coma. Diabetes 1975; 24: 594-599
16. Hellweg R, Hartung HD. Endogenous levels of nerve growth factor (NGF) are altered in experimental diabetes mellitus: a possible role for NGF in the pathogenesis of diabetic neuropathy. J Neurosci Res 1990; 26: 258-267
17. Humpert PM, Papadopoulos G, Schaefer K et al. sRAGE and esRAGE are not associated with peripheral or autonomic neuropathy in type 2 diabetes. Horm Metab Res 2007; 39: 899-902
18. Jakobsen J, Brimijoin S, Skau K, Sidenius P, Wells D. Retrograde axonal transport of transmitter enzymes, fucose-labeled protein, and nerve growth factor in streptozotocin-diabetic rats. Diabetes 1981; 30: 797-803
19. Kasalova Z, Prazny M, Skrha J. Relationship between peripheral diabetic neuropathy and microvascular reactivity in patients with type 1 and type 2 diabetes mellitus - neuropathy and microcirculation in diabetes. Exp Clin Endocrinol Diabetes 2006; 114: 52-57
20. Kennedy JM, Zochodne DW. The regenerative deficit of peripheral nerves in experimental diabetes: its extent, timing and possible mechanisms. Brain 2000; 123 (Pt 10): 2118-2129
21. Kim B, Feldman EL. Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt. J Biol Chem 2002; 277: 27393-27400
22. Ko BC, Ruepp B, Bohren KM, Gabbay KH, Chung SS. Identification and characterization of multiple osmotic response sequences in the human aldose reductase gene. J Biol Chem 1997; 272: 16431-16437
23. Maekawa K, Tanimoto T, Okada S, Suzuki T, Yabe-Nishimura C. Expression of aldose reductase and sorbitol dehydrogenase genes in Schwann cells isolated from rat: effects of high glucose and osmotic stress. Brain Res Mol Brain Res 2001; 87: 251-256
24. Matsuka Y, Spigelman I. Hyperosmolar solutions selectively block action potentials in rat myelinated sensory fibers: implications for diabetic neuropathy. J Neurophysiol 2004; 91: 48-56
25. Matthews CC, Feldman EL. Insulin-like growth factor I rescues SH-SY5Y human neuroblastoma cells from hyperosmotic induced programmed cell death. J Cell Physiol 1996; 166: 323-331
26. Mizisin AP, Li L, Calcutt NA. Sorbitol accumulation and transmembrane efflux in osmotically stressed JS1 schwannoma cells. Neurosci Lett 1997; 229: 53-56
27. Mizisin AP, Li L, Perello M, Freshwater JD, Kalichman MW, Roux L, Calcutt NA. Polyol pathway and osmoregulation in JS1 Schwann cells grown in hyperglycemic and hyperosmotic conditions. Am J Physiol 1996; 270: F90-97
28. Mohiuddin L, Tomlinson DR. Impaired molecular regenerative responses in sensory neurones of diabetic rats: gene expression changes in dorsal root ganglia after sciatic nerve crush. Diabetes 1997; 46: 2057-2062
29. Nukada H, Dyck PJ, Low PA, Lais AC, Sparks MF. Axonal caliber and neurofilaments are proportionately decreased in galactose neuropathy. J Neuropathol Exp Neurol 1986; 45: 140-150
30. Öztürk G, Şekeroǧlu MR, Erdoǧan E, Öztürk M. The effect of non-enzymatic glycation of extracellular matrix proteins on axonal regeneration in vitro. Acta Neuropathol 2006; 112: 627-632
31. Öztürk G, Erdoǧan E. Multidimensional long-term time-lapse microscopy of in vitro peripheral nerve regeneration. Microsc Res Tech 2004; 64: 228-242
32. Raghavendra S, Ashalatha R, Thomas SV, Kesavadas C. Focal neuronal loss, reversible subcortical focal T2 hypointensity in seizures with a nonketotic hyperglycemic hyperosmolar state. Neuroradiology 2007; 49: 299-305
33. Reinehr R, Haussinger D. Hyperosmotic activation of the CD95 system. Methods in enzymology 2007; 428: 145-160
34. Ruepp B, Bohren KM, Gabbay KH. Characterization of the osmotic response element of the human aldose reductase gene promoter. Proc Natl Acad Sci U S A 1996; 93: 8624-8629
35. Russell JW, Sullivan KA, Windebank AJ, Herrmann DN, Feldman EL. Neurons undergo apoptosis in animal and cell culture models of diabetes. Neurobiol Dis 1999; 6: 347-363
36. Scott JN, Clark AW, Zochodne DW. Neurofilament and tubulin gene expression in progressive experimental diabetes: failure of synthesis and export by sensory neurons. Brain 1999; 122 (Pt 11): 2109-2118
37. Sima AA, Sugimoto K. Experimental diabetic neuropathy: an update. Diabetologia 1999; 42: 773-788
38. Sugimura K, Windebank AJ, Natarajan V et al. Interstitial hyperosmolarity may cause axis cylinder shrinkage in streptozotocin diabetic nerve. J Neuropathol Exp Neurol 1980; 39: 710-721
39. Sugimoto K, Murakawa Y, Sima AA. Diabetic neuropathy - a continuing enigma. Diabetes Metab Res Rev 2000; 16: 408-433
40. Tilton RG, Chang K, Nyengaard JR, Enden M Van den, Ido Y, Williamson JR. Inhibition of sorbitol dehydrogenase. Effects on vascular and neural dysfunction in streptozocin-induced diabetic rats. Diabetes 1995; 44: 234-242
41. Tonge D, Edstrom A, Ekstrom P. Use of explant cultures of peripheral nerves of adult vertebrates to study axonal regeneration in vitro. Prog Neurobiol 1998; 54: 459-480
42. Unger JW, Klitzsch T, Pera S, Reiter R. Nerve growth factor (NGF) and diabetic neuropathy in the rat: morphological investigations of the sural nerve, dorsal root ganglion, and spinal cord. Exp Neurol 1998; 153: 23-34
43. Williamson JR, Chang K, Frangos M, Hasan KS, Ido Y, Kawamura T, Nyengaard JR, Enden M van den, Kilo C, Tilton RG. Hyperglycemic pseudohypoxia and diabetic complications. Diabetes 1993; 42: 801-813
44. Zhuang HX, Wuarin L, Fei ZJ, Ishii DN. Insulin-like growth factor (IGF) gene expression is reduced in neural tissues and liver from rats with non-insulin-dependent diabetes mellitus, and IGF treatment ameliorates diabetic neuropathy. J Pharmacol Exp Ther 1997; 283: 366-374
45. Zochodne DW, Verge VM, Cheng C, Sun H, Johnston J. Does diabetes target ganglion neurones? Progressive sensory neurone involvement in long-term experimental diabetes. Brain 2001; 124: 2319-2334