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Volumn 42, Issue 6, 1993, Pages 801-813

Hyperglycemic pseudohypoxia and diabetic complications

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; FATTY ACID; GALACTOSE; GLUCOSE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NITRIC OXIDE; OXYGEN RADICAL; PROSTAGLANDIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SORBITOL; SUPEROXIDE;

EID: 0027318772     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.42.6.801     Document Type: Review
Times cited : (1058)

References (143)
  • 2
    • 0025814611 scopus 로고
    • Nerve blood flow in early experimental diabetes in rats: Relation to conduction deficits
    • Cameron NE, Cotter MA, Low PA: Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits. Am J Physiol 261:E1-E8, 1991
    • (1991) Am J Physiol , vol.261
    • Cameron, N.E.1    Cotter, M.A.2    Low, P.A.3
  • 3
    • 0001424699 scopus 로고
    • Protein kinase C (PKC) activation is a causal factor for the alteration of retinal blood flow in diabetes of short duration
    • Shiba T, Bursell SE, Clermont A, Sportsman R, Heath W, King GL: Protein kinase C (PKC) activation is a causal factor for the alteration of retinal blood flow in diabetes of short duration (Abstract). Invest Ophthalmol Visual Sci 32:785, 1991
    • (1991) Invest Ophthalmol Visual Sci , vol.32 , pp. 785
    • Shiba, T.1    Bursell, S.E.2    Clermont, A.3    Sportsman, R.4    Heath, W.5    King, G.L.6
  • 4
    • 0018909486 scopus 로고
    • 2 clearance measurement of blood flow: A review of technique and polarographic principles
    • 2 clearance measurement of blood flow: a review of technique and polarographic principles. Stroke 11:552-64, 1980
    • (1980) Stroke , vol.11 , pp. 552-564
    • Young, W.1
  • 5
    • 0026596711 scopus 로고
    • Functional consequences of streptozotocin-induced diabetes mellitus, with particular reference to the cardiovascular system
    • Tomlinson KC, Gardiner SM, Hebden RA, Bennett T: Functional consequences of streptozotocin-induced diabetes mellitus, with particular reference to the cardiovascular system. Pharmacol Rev 44:103-50, 1992
    • (1992) Pharmacol Rev , vol.44 , pp. 103-150
    • Tomlinson, K.C.1    Gardiner, S.M.2    Hebden, R.A.3    Bennett, T.4
  • 6
    • 0022160189 scopus 로고
    • Pressor factors and responsiveness in hypertension accompanying diabetes mellitus
    • Weidmann P, Beretta-Piccoli C, Trost BN: Pressor factors and responsiveness in hypertension accompanying diabetes mellitus. Hypertension 7 (Suppl. 2):33-42, 1985
    • (1985) Hypertension , vol.7 , Issue.2 SUPPL. , pp. 33-42
    • Weidmann, P.1    Beretta-Piccoli, C.2    Trost, B.N.3
  • 9
    • 0026704953 scopus 로고
    • Concurrent increases in regional hematocrit and blood flow in diabetic rats: Prevention by sorbinil
    • Sutera SP, Chang K, Marvel J, Williamson JR: Concurrent increases in regional hematocrit and blood flow in diabetic rats: prevention by sorbinil. Am J Physiol 263:H945-50, 1992
    • (1992) Am J Physiol , vol.263
    • Sutera, S.P.1    Chang, K.2    Marvel, J.3    Williamson, J.R.4
  • 11
    • 0020655710 scopus 로고
    • Response of choroidal vascular resistance to hyperglycemia
    • Ernest JT, Goldstick TK: Response of choroidal vascular resistance to hyperglycemia. Int Ophthalmol 6:119-24, 1983
    • (1983) Int Ophthalmol , vol.6 , pp. 119-124
    • Ernest, J.T.1    Goldstick, T.K.2
  • 15
    • 0026808941 scopus 로고
    • Relation of skin capillary pressure in patients with insulin-dependent diabetes mellitus to complications and metabolic control
    • Sandeman DD, Shore AC, Tooke JE: Relation of skin capillary pressure in patients with insulin-dependent diabetes mellitus to complications and metabolic control. N Engl J Med 327:760-64, 1992
    • (1992) N Engl J Med , vol.327 , pp. 760-764
    • Sandeman, D.D.1    Shore, A.C.2    Tooke, J.E.3
  • 17
    • 1842362824 scopus 로고
    • Glucose-induced increases in regional blood flow are prevented by aminoguanidine and L-NMMA, inhibitors of nitric oxide synthase
    • Hasan KS, Chang K, Allison W, Faller A, Santiago JV, Tilton RG, Williamson JR: Glucose-induced increases in regional blood flow are prevented by aminoguanidine and L-NMMA, inhibitors of nitric oxide synthase. (Abstract) FASEB J 7(Part I):A105, 1993
    • (1993) FASEB J , vol.7 , Issue.1 PART
    • Hasan, K.S.1    Chang, K.2    Allison, W.3    Faller, A.4    Santiago, J.V.5    Tilton, R.G.6    Williamson, J.R.7
  • 19
    • 0016425953 scopus 로고
    • Relationship between oxygen tension, coronary vasodilation and prostaglandin biosynthesis in the isolated rabbit heart
    • Needleman P, Key SL, Isakson PC, Kulkarni PS: Relationship between oxygen tension, coronary vasodilation and prostaglandin biosynthesis in the isolated rabbit heart. Prostaglandins 9:123-34, 1975
    • (1975) Prostaglandins , vol.9 , pp. 123-134
    • Needleman, P.1    Key, S.L.2    Isakson, P.C.3    Kulkarni, P.S.4
  • 20
    • 0021806702 scopus 로고
    • Retinal vascular autoregulation in conditions of hyperoxia and hypoxia using the blue field entoptic phenomenon
    • Fallon TJ, Maxwell D, Kohner EM: Retinal vascular autoregulation in conditions of hyperoxia and hypoxia using the blue field entoptic phenomenon. Ophthalmology 92:701-705, 1985
    • (1985) Ophthalmology , vol.92 , pp. 701-705
    • Fallon, T.J.1    Maxwell, D.2    Kohner, E.M.3
  • 21
    • 0026518370 scopus 로고
    • Role of nitric oxide in reactive hyperemia of the guinea pig heart
    • Kostic MM, Schrader J: Role of nitric oxide in reactive hyperemia of the guinea pig heart. Circ Res 70:208-12, 1992
    • (1992) Circ Res , vol.70 , pp. 208-212
    • Kostic, M.M.1    Schrader, J.2
  • 22
    • 0026800747 scopus 로고
    • Nitric oxide is a mediator of hypoxic coronary vasodilatation: Relation to adenosine and cyclooxygenase-derived metabolites
    • Park KH, Rubin LE, Gross SS, Levi R: Nitric oxide is a mediator of hypoxic coronary vasodilatation: relation to adenosine and cyclooxygenase-derived metabolites. Circ Res 71:992-1001, 1992
    • (1992) Circ Res , vol.71 , pp. 992-1001
    • Park, K.H.1    Rubin, L.E.2    Gross, S.S.3    Levi, R.4
  • 23
    • 0014082605 scopus 로고
    • The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver
    • Williamson DH, Lund P, Krebs HA: The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochem J 103:514-27, 1967
    • (1967) Biochem J , vol.103 , pp. 514-527
    • Williamson, D.H.1    Lund, P.2    Krebs, H.A.3
  • 24
    • 0015137314 scopus 로고
    • Metabolic alterations in the human erythrocyte produced by increases in glucose concentration: The role of the polyol pathway
    • Travis SF, Morrison AD, Clements RS Jr, Winegrad AI, Oski FA: Metabolic alterations in the human erythrocyte produced by increases in glucose concentration: the role of the polyol pathway. J. Clin Invest 50:2104-12, 1971
    • (1971) J. Clin Invest , vol.50 , pp. 2104-2112
    • Travis, S.F.1    Morrison, A.D.2    Clements Jr., R.S.3    Winegrad, A.I.4    Oski, F.A.5
  • 25
    • 0017661507 scopus 로고
    • Regulation of alanine formation and release in rat muscle in vivo: Effect of starvation and diabetes
    • Ruderman NB, Schmahl FW, Goodman MN: Regulation of alanine formation and release in rat muscle in vivo: effect of starvation and diabetes. Am J Physiol 233:E109-14, 1977
    • (1977) Am J Physiol , vol.233
    • Ruderman, N.B.1    Schmahl, F.W.2    Goodman, M.N.3
  • 26
    • 0025767877 scopus 로고
    • Glucose-induced metabolic imbalances in the pathogenesis of diabetic vascular disease
    • Pugliese G, Tilton RG, Williamson JR: Glucose-induced metabolic imbalances in the pathogenesis of diabetic vascular disease. Diabetes Metab Rev 7:35-59, 1991
    • (1991) Diabetes Metab Rev , vol.7 , pp. 35-59
    • Pugliese, G.1    Tilton, R.G.2    Williamson, J.R.3
  • 27
    • 0002107564 scopus 로고
    • Mechanisms of glucose- And diabetes-induced vascular dysfunction
    • Ruderman NB, Williamson JR, Brownlee M, Eds. New York, Oxford Univ. Press
    • Williamson JR, Kilo C, Tilton RG: Mechanisms of glucose- and diabetes-induced vascular dysfunction. In Hyperglycemia, Diabetes, and Vascular Disease. Ruderman NB, Williamson JR, Brownlee M, Eds. New York, Oxford Univ. Press, 1992, p. 107-32
    • (1992) Hyperglycemia, Diabetes, and Vascular Disease , pp. 107-132
    • Williamson, J.R.1    Kilo, C.2    Tilton, R.G.3
  • 28
    • 85034938207 scopus 로고
    • The role of "hyperglycemic (metabolic) hypoxia" in the pathogenesis of diabetic complications
    • Van den Enden M, Ostrow E, Williamson JR: The role of "hyperglycemic (metabolic) hypoxia" in the pathogenesis of diabetic complications (Abstract). Diabetologia 35 (Suppl. 1):A46, 1992
    • (1992) Diabetologia , vol.35 , Issue.1 SUPPL.
    • Van Den Enden, M.1    Ostrow, E.2    Williamson, J.R.3
  • 29
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes JW: Role of oxidative stress in development of complications in diabetes. Diabetes 40:405-12, 1991
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 30
    • 0020427486 scopus 로고
    • Biology of disease: Free radicals and tissue injury
    • Freeman BA, Crapo JD: Biology of disease: free radicals and tissue injury. Lab Invest 47:412-26, 1982
    • (1982) Lab Invest , vol.47 , pp. 412-426
    • Freeman, B.A.1    Crapo, J.D.2
  • 31
    • 0021209872 scopus 로고
    • Amphipathic metabolites and membrane dysfunction in ischemic myocardium
    • Corr PB, Gross RW, Sobel BE. Amphipathic metabolites and membrane dysfunction in ischemic myocardium. Circ Res 55:135-54, 1984
    • (1984) Circ Res , vol.55 , pp. 135-154
    • Corr, P.B.1    Gross, R.W.2    Sobel, B.E.3
  • 32
    • 0022579328 scopus 로고
    • Diabetes-induced abnormalities in the myocardium
    • Tahiliani AG, McNeill JH: Diabetes-induced abnormalities in the myocardium. Life Sci 38:959-74, 1986
    • (1986) Life Sci , vol.38 , pp. 959-974
    • Tahiliani, A.G.1    McNeill, J.H.2
  • 34
    • 0023575388 scopus 로고
    • Does a common mechanism induce the diverse complications of diabetes?
    • Winegrad AI: Does a common mechanism induce the diverse complications of diabetes? Diabetes 36:396-406, 1987
    • (1987) Diabetes , vol.36 , pp. 396-406
    • Winegrad, A.I.1
  • 35
    • 0023892306 scopus 로고
    • Diabetic cardiopathy: Is it a real entity?
    • Crepaldi G, Nosadini R: Diabetic cardiopathy: Is it a real entity? Diabetes Metab Rev 4:273-88, 1988
    • (1988) Diabetes Metab Rev , vol.4 , pp. 273-288
    • Crepaldi, G.1    Nosadini, R.2
  • 36
    • 0023913225 scopus 로고
    • The involvement of aldose reductase in diabetic complications
    • Kinoshita JH, Nishimura C: The involvement of aldose reductase in diabetic complications. Diabetes Metab Rev 4:323-37, 1988
    • (1988) Diabetes Metab Rev , vol.4 , pp. 323-337
    • Kinoshita, J.H.1    Nishimura, C.2
  • 37
    • 0023803371 scopus 로고
    • Advanced products of nonenzymatic glycosylation and the pathogenesis of diabetic vascular disease
    • Brownlee M, Cerami A, Vlassara H: Advanced products of nonenzymatic glycosylation and the pathogenesis of diabetic vascular disease. Diabetes Metab Rev 4:437-51, 1988
    • (1988) Diabetes Metab Rev , vol.4 , pp. 437-451
    • Brownlee, M.1    Cerami, A.2    Vlassara, H.3
  • 43
    • 0024395624 scopus 로고
    • Contractile properties of cardiac papillary muscle in streptozotocin-diabetic rats and the effects of aldose reductase inhibition
    • Cameron NE, Cotter MA, Robertson S: Contractile properties of cardiac papillary muscle in streptozotocin-diabetic rats and the effects of aldose reductase inhibition. Diabetologia 32:365-70, 1989
    • (1989) Diabetologia , vol.32 , pp. 365-370
    • Cameron, N.E.1    Cotter, M.A.2    Robertson, S.3
  • 44
    • 0025343707 scopus 로고
    • Changes in skeletal muscle contractile properties in streptozocin-induced diabetic rats and role of polyol pathway and hypoinsulinemia
    • Cameron NE, Cotter MA, Robertson S: Changes in skeletal muscle contractile properties in streptozocin-induced diabetic rats and role of polyol pathway and hypoinsulinemia. Diabetes 39:460-65, 1990
    • (1990) Diabetes , vol.39 , pp. 460-465
    • Cameron, N.E.1    Cotter, M.A.2    Robertson, S.3
  • 45
    • 0025956755 scopus 로고
    • Characterization of a novel aldose reductase inhibitor, FR74366, and its effects on diabetic cataract and neuropathy in the rat
    • Ao S, Shingu Y, Kikuchi C, Takano Y, Nomura K, Fujiwara T, Ohkubo Y, Notsu Y, Yamaguchi I: Characterization of a novel aldose reductase inhibitor, FR74366, and its effects on diabetic cataract and neuropathy in the rat. Metabolism 40:77-87, 1991
    • (1991) Metabolism , vol.40 , pp. 77-87
    • Ao, S.1    Shingu, Y.2    Kikuchi, C.3    Takano, Y.4    Nomura, K.5    Fujiwara, T.6    Ohkubo, Y.7    Notsu, Y.8    Yamaguchi, I.9
  • 46
    • 0026738167 scopus 로고
    • Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: Role of polyol pathway
    • Cameron NE, Cotter MA: Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: role of polyol pathway. Diabetologia 35:1011-19, 1992
    • (1992) Diabetologia , vol.35 , pp. 1011-1019
    • Cameron, N.E.1    Cotter, M.A.2
  • 47
    • 0026438753 scopus 로고
    • Dissociation between biochemical and functional effects of the aldose reductase inhibitor, ponalrestat, on peripheral nerve in diabetic rats
    • Cameron NE, Cotter MA: Dissociation between biochemical and functional effects of the aldose reductase inhibitor, ponalrestat, on peripheral nerve in diabetic rats. Br J Pharmacol 107:939-44, 1992
    • (1992) Br J Pharmacol , vol.107 , pp. 939-944
    • Cameron, N.E.1    Cotter, M.A.2
  • 48
    • 0002749064 scopus 로고
    • Diabetes mellitus and the vascular endothelium
    • Ruderman NB, Williamson JR, Brownlee M, Eds. New York, Oxford Univ. Press
    • Cohen RA, Tesfamariam B: Diabetes mellitus and the vascular endothelium. In Hyperglycemia, Diabetes, and Vascular Disease Ruderman NB, Williamson JR, Brownlee M, Eds. New York, Oxford Univ. Press, 1992, p. 48-58
    • (1992) Hyperglycemia, Diabetes, and Vascular Disease , pp. 48-58
    • Cohen, R.A.1    Tesfamariam, B.2
  • 49
    • 0018383065 scopus 로고
    • Effects of ischemia on rat myocardial function and metabolism in diabetes
    • Feuvray D, Idell-Wenger JA, Neely JR: Effects of ischemia on rat myocardial function and metabolism in diabetes. Circ Res 44:322-29, 1979
    • (1979) Circ Res , vol.44 , pp. 322-329
    • Feuvray, D.1    Idell-Wenger, J.A.2    Neely, J.R.3
  • 50
    • 0024463232 scopus 로고
    • Myocyte contracture, vascular resistance, and vascular permeability after global ischemia in isolated hearts from alloxan-induced diabetic rabbits
    • Tilton R, Daugherty A, Sutera SP, Larson KB, Land MP, Rateri DL, Kilo C, Williamson JR: Myocyte contracture, vascular resistance, and vascular permeability after global ischemia in isolated hearts from alloxan-induced diabetic rabbits. Diabetes 38:1484-91, 1989
    • (1989) Diabetes , vol.38 , pp. 1484-1491
    • Tilton, R.1    Daugherty, A.2    Sutera, S.P.3    Larson, K.B.4    Land, M.P.5    Rateri, D.L.6    Kilo, C.7    Williamson, J.R.8
  • 53
    • 0023117669 scopus 로고
    • Recent advances in the pathogenesis of diabetic neuropathy
    • Low PA: Recent advances in the pathogenesis of diabetic neuropathy. Muscle Nerve 10:121-28, 1987
    • (1987) Muscle Nerve , vol.10 , pp. 121-128
    • Low, P.A.1
  • 54
    • 0014811206 scopus 로고
    • + content on the pathways of carbohydrate metabolism and lipogenesis in rat liver
    • + content on the pathways of carbohydrate metabolism and lipogenesis in rat liver. Eur J Biochem 15:179-90, 1970
    • (1970) Eur J Biochem , vol.15 , pp. 179-190
    • Lagunas, R.1    McLean, P.2    Greenbaum, A.L.3
  • 55
    • 0022650672 scopus 로고
    • The effect of high glucose and oxidative stress on lens metabolism, aldose reductase, and senile cataractogenesis
    • Cheng HM, González RG: The effect of high glucose and oxidative stress on lens metabolism, aldose reductase, and senile cataractogenesis. Metabolism 35 (Suppl. 1):10-14, 1986
    • (1986) Metabolism , vol.35 , Issue.1 SUPPL. , pp. 10-14
    • Cheng, H.M.1    González, R.G.2
  • 56
    • 0023079264 scopus 로고
    • Characterization of aldose reductase activities from human and animal sources by a sensitive fluorescence assay
    • Weiner H, Ed. New York, Liss
    • Griffin BW, McNatt LG, York BM Jr: Characterization of aldose reductase activities from human and animal sources by a sensitive fluorescence assay. In Enzymology and Molecular Biology and Carbonyl Metabolism Weiner H, Ed. New York, Liss, 1987, p. 325-40
    • (1987) Enzymology and Molecular Biology and Carbonyl Metabolism , pp. 325-340
    • Griffin, B.W.1    McNatt, L.G.2    York Jr., B.M.3
  • 57
    • 0014011574 scopus 로고
    • Control of glycolysis in the human red blood cell
    • Rose IA, Warms JVB: Control of glycolysis in the human red blood cell. J Biol Chem 241:4848-54, 1966
    • (1966) J Biol Chem , vol.241 , pp. 4848-4854
    • Rose, I.A.1    Warms, J.V.B.2
  • 58
    • 0018371606 scopus 로고
    • Control of maximum rates of glycolysis in rat cardiac muscle
    • Kobayashi K, Neely JR: Control of maximum rates of glycolysis in rat cardiac muscle. Circ Res 44:166-75, 1979
    • (1979) Circ Res , vol.44 , pp. 166-175
    • Kobayashi, K.1    Neely, J.R.2
  • 59
    • 24444446046 scopus 로고
    • Sorbitol-induced imbalances in glycolysis in human erythrocytes are reduced by pyruvate
    • Frangos M, Smith S, Santiago J, Kilo C: Sorbitol-induced imbalances in glycolysis in human erythrocytes are reduced by pyruvate (Abstract). Diabetes 39 (Suppl. 1):274A, 1990
    • (1990) Diabetes , vol.39 , Issue.1 SUPPL.
    • Frangos, M.1    Smith, S.2    Santiago, J.3    Kilo, C.4
  • 60
    • 85034941753 scopus 로고
    • Inhibition of retinal vascular dysfunction in diabetic rats by S-0773, an inhibitor of sorbitol dehydrogenase
    • Williamson JR, Chang K, Allison W, Burgan J, Tilton RG: Inhibition of retinal vascular dysfunction in diabetic rats by S-0773, an inhibitor of sorbitol dehydrogenase (Abstract). Invest Ophthalmol Visual Sci 34:712, 1993
    • (1993) Invest Ophthalmol Visual Sci , vol.34 , pp. 712
    • Williamson, J.R.1    Chang, K.2    Allison, W.3    Burgan, J.4    Tilton, R.G.5
  • 61
    • 85034937412 scopus 로고    scopus 로고
    • Sorbitol dehydrogenase inhibition (SDI) attenuates sciatic nerve vascular dysfunction in diabetic rats
    • In press
    • Williamson JR, Chang K, Allison W, Smith SR, Burgan J, Tilton RG: Sorbitol dehydrogenase inhibition (SDI) attenuates sciatic nerve vascular dysfunction in diabetic rats (Abstract). Diabetes. In press
    • Diabetes
    • Williamson, J.R.1    Chang, K.2    Allison, W.3    Smith, S.R.4    Burgan, J.5    Tilton, R.G.6
  • 62
    • 0026035977 scopus 로고
    • Diacylglycerol accumulation and microvascular abnormalities induced by elevated glucose levels
    • Wolf BA, Williamson JR, Easom RA, Chang K, Sherman WR, Turk J: Diacylglycerol accumulation and microvascular abnormalities induced by elevated glucose levels. J Clin Invest 87:31-38, 1990
    • (1990) J Clin Invest , vol.87 , pp. 31-38
    • Wolf, B.A.1    Williamson, J.R.2    Easom, R.A.3    Chang, K.4    Sherman, W.R.5    Turk, J.6
  • 63
    • 85034935528 scopus 로고    scopus 로고
    • Acute hyperglycemia-induced increases in regional blood flow are prevented by pyruvate and by tolrestat
    • In press
    • Hasan KS, Santiago JV, Williamson JR: Acute hyperglycemia-induced increases in regional blood flow are prevented by pyruvate and by tolrestat (Abstract). Diabetes. In press
    • Diabetes
    • Hasan, K.S.1    Santiago, J.V.2    Williamson, J.R.3
  • 64
    • 12644250181 scopus 로고
    • Sorbitol-induced increases in vascular albumin clearance (VAC) are prevented by pyruvate but not myo-inositol
    • Williamson JR, Chang K, Ostrow E, Allison W, Harlow J, Kilo C: Sorbitol-induced increases in vascular albumin clearance (VAC) are prevented by pyruvate but not myo-inositol (Abstract). Diabetes 38:94A, 1989
    • (1989) Diabetes , vol.38
    • Williamson, J.R.1    Chang, K.2    Ostrow, E.3    Allison, W.4    Harlow, J.5    Kilo, C.6
  • 67
    • 0024563795 scopus 로고
    • Protein kinase C is activated in glomeruli from streptozotocin diabetic rats
    • Craven PA, DeRubertis FR: Protein kinase C is activated in glomeruli from streptozotocin diabetic rats. J Clin Invest 83:1667-75, 1989
    • (1989) J Clin Invest , vol.83 , pp. 1667-1675
    • Craven, P.A.1    DeRubertis, F.R.2
  • 68
    • 0000358508 scopus 로고
    • Activation of protein kinase C by elevation of glucose concentration: Proposal for a mechanism in the development of diabetic vascular complications
    • Lee T-S, Saltsman KA, Ohashi H, King GL: Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications. Proc Natl Acad Sci USA 86:5141-45, 1989
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5141-5145
    • Lee, T.-S.1    Saltsman, K.A.2    Ohashi, H.3    King, G.L.4
  • 69
    • 0025313272 scopus 로고
    • Increase in diacylglycerol mass in isolated glomeruli by glucose from de novo synthesis of glycerolipids
    • Craven PA, Davidson CM, DeRubertis FR: Increase in diacylglycerol mass in isolated glomeruli by glucose from de novo synthesis of glycerolipids. Diabetes 39:667-74, 1990
    • (1990) Diabetes , vol.39 , pp. 667-674
    • Craven, P.A.1    Davidson, C.M.2    DeRubertis, F.R.3
  • 70
    • 0027526475 scopus 로고
    • +-ATPase activity in sciatic nerve of diabetic mice by administration of H7 or callphostin C, inhibitors of protein kinase C
    • +-ATPase activity in sciatic nerve of diabetic mice by administration of H7 or callphostin C, inhibitors of protein kinase C. Diabetes 42:257-62,1993
    • (1993) Diabetes , vol.42 , pp. 257-262
    • Hermenegildo, C.1    Felipo, V.2    Miñana, M.D.3    Romero, F.J.4    Grisolia, S.5
  • 71
    • 0011779134 scopus 로고
    • Cell culture model for the study of vascular complications of diabetes: The effect of high glucose levels on metabolism and growth of vascular cells
    • Ruderman NB, Williamson JR, Brownlee M, Eds. New York, Oxford Univ. Press
    • King GL, Shiba T, Feener EP, Nayak R: Cell culture model for the study of vascular complications of diabetes: the effect of high glucose levels on metabolism and growth of vascular cells. In Hyperglycemia, Diabetes, and Vascular Disease Ruderman NB, Williamson JR, Brownlee M, Eds. New York, Oxford Univ. Press, 1992, p. 162-77
    • (1992) Hyperglycemia, Diabetes, and Vascular Disease , pp. 162-177
    • King, G.L.1    Shiba, T.2    Feener, E.P.3    Nayak, R.4
  • 72
    • 0024994545 scopus 로고
    • 1,2-diacylglycerol content and its arachidonyl-containing molecular species are reduced in sciatic nerve from streptozotocin-induced diabetic rats
    • Zhu X, Eichberg J: 1,2-diacylglycerol content and its arachidonyl-containing molecular species are reduced in sciatic nerve from streptozotocin-induced diabetic rats. J Neurochem 55:1087-90, 1990
    • (1990) J Neurochem , vol.55 , pp. 1087-1090
    • Zhu, X.1    Eichberg, J.2
  • 73
    • 0025878775 scopus 로고
    • 1,2-diacylglycerol content and its fatty acid composition in thoracic aorta of diabetic rats
    • Okumura K, Nishiura T, Awaji Y, Kondo J, Hashimoto H, Ito T: 1,2-diacylglycerol content and its fatty acid composition in thoracic aorta of diabetic rats Diabetes 40:820-24, 1991
    • (1991) Diabetes , vol.40 , pp. 820-824
    • Okumura, K.1    Nishiura, T.2    Awaji, Y.3    Kondo, J.4    Hashimoto, H.5    Ito, T.6
  • 74
    • 0026783660 scopus 로고
    • Characterization of glucose-induced in situ protein kinase C activity in cultured vascular smooth muscle cells
    • Williams B, Schrier RW: Characterization of glucose-induced in situ protein kinase C activity in cultured vascular smooth muscle cells. Diabetes 41:1464-72, 1992
    • (1992) Diabetes , vol.41 , pp. 1464-1472
    • Williams, B.1    Schrier, R.W.2
  • 75
    • 0021722729 scopus 로고
    • The interaction of lithium with thyrotropin-releasing hormone-stimulated lipid metabolism in GH3 pituitary tumour cells
    • Drummond AH, Raeburn CA: The interaction of lithium with thyrotropin-releasing hormone-stimulated lipid metabolism in GH3 pituitary tumour cells. Biochem J 224:129-36, 1984
    • (1984) Biochem J , vol.224 , pp. 129-136
    • Drummond, A.H.1    Raeburn, C.A.2
  • 76
    • 0022466347 scopus 로고
    • Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland
    • Downes CP, Stone MA: Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland. Biochem J 234:199-204, 1986
    • (1986) Biochem J , vol.234 , pp. 199-204
    • Downes, C.P.1    Stone, M.A.2
  • 77
    • 0024341795 scopus 로고
    • Neural and developmental actions of lithium: A unifying hypothesis
    • Berridge MJ, Downes CP, Hanley MJ: Neural and developmental actions of lithium: a unifying hypothesis. Cell 59:411-19, 1989
    • (1989) Cell , vol.59 , pp. 411-419
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.J.3
  • 78
    • 0024507366 scopus 로고
    • Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol
    • Godfrey PP: Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol. Biochem J 258:621-24, 1989
    • (1989) Biochem J , vol.258 , pp. 621-624
    • Godfrey, P.P.1
  • 79
    • 0013923479 scopus 로고
    • Mechanism for the stimulation of gluconeogenesis by fatty acids in perfused rat liver
    • Williamson JR, Kreisberg RA, Felts PW: Mechanism for the stimulation of gluconeogenesis by fatty acids in perfused rat liver. Proc Natl Acad Sci USA 56:247-54, 1966
    • (1966) Proc Natl Acad Sci USA , vol.56 , pp. 247-254
    • Williamson, J.R.1    Kreisberg, R.A.2    Felts, P.W.3
  • 80
    • 0017161616 scopus 로고
    • Effects of mechanical activity and hormones on myocardial glucose and fatty acid utilization
    • Neely JR, Whitmer KM, Mochizuki S: Effects of mechanical activity and hormones on myocardial glucose and fatty acid utilization. Circ Res 38 (Suppl. 1):22-30, 1976
    • (1976) Circ Res , vol.38 , Issue.1 SUPPL. , pp. 22-30
    • Neely, J.R.1    Whitmer, K.M.2    Mochizuki, S.3
  • 81
    • 0022639425 scopus 로고
    • The dependence of electro-physiological derangements on accumulation of endogenous long-chain acyl carnitine in hypoxic neonatal rat myocytes
    • Knabb MT, Saffitz JE, Corr PB, Sobel BE: The dependence of electro-physiological derangements on accumulation of endogenous long-chain acyl carnitine in hypoxic neonatal rat myocytes. Circ Res 58:230-40, 1986
    • (1986) Circ Res , vol.58 , pp. 230-240
    • Knabb, M.T.1    Saffitz, J.E.2    Corr, P.B.3    Sobel, B.E.4
  • 82
    • 0024551414 scopus 로고
    • Prophylaxis of early ventricular fibrillation by inhibition of acylcarnitine accumulation
    • Corr PB, Creer MH, Yamada KA, Saffitz JE, Sobel BE: Prophylaxis of early ventricular fibrillation by inhibition of acylcarnitine accumulation. J Clin Invest 83:927-36, 1989
    • (1989) J Clin Invest , vol.83 , pp. 927-936
    • Corr, P.B.1    Creer, M.H.2    Yamada, K.A.3    Saffitz, J.E.4    Sobel, B.E.5
  • 84
    • 4244136354 scopus 로고
    • Acetylcarnitine improves neuronal function in streptozotocin (STZ) diabetic rats
    • Lowitt S, Malone JI, Salem A, Korthals J: Acetylcarnitine improves neuronal function in streptozotocin (STZ) diabetic rats (Abstract). Diabetes 39 (Suppl. 1):155A, 1990
    • (1990) Diabetes , vol.39 , Issue.1 SUPPL.
    • Lowitt, S.1    Malone, J.I.2    Salem, A.3    Korthals, J.4
  • 86
    • 0020170579 scopus 로고
    • A mechanism for reduced myocardial carnitine levels in diabetic animals
    • Vary TC, Neely JR: A mechanism for reduced myocardial carnitine levels in diabetic animals. Am J Physiol 243:H154-58, 1982
    • (1982) Am J Physiol , vol.243
    • Vary, T.C.1    Neely, J.R.2
  • 87
    • 85034933035 scopus 로고    scopus 로고
    • Effects of acetyl-L-carnitine (AC) on functional and metabolic abnormalities in diabetic peripheral nerve
    • In press
    • Ido Y, Rattarasarn M, Allison W, Orfalian Z, Arrigoni-Martelli E: Effects of acetyl-L-carnitine (AC) on functional and metabolic abnormalities in diabetic peripheral nerve (Abstract). Diabetes. In press
    • Diabetes
    • Ido, Y.1    Rattarasarn, M.2    Allison, W.3    Orfalian, Z.4    Arrigoni-Martelli, E.5
  • 88
    • 0023622082 scopus 로고
    • Effect of ambient oxygen on cultured endothelial cells from different vascular beds
    • Farber HW, Center DM, Rounds S: Effect of ambient oxygen on cultured endothelial cells from different vascular beds. Am J Physiol 253:H878-83, 1987
    • (1987) Am J Physiol , vol.253
    • Farber, H.W.1    Center, D.M.2    Rounds, S.3
  • 89
    • 0025803078 scopus 로고
    • Differences in prostaglandin metabolism in cultured aortic and pulmonary arterial endothelial cells exposed to acute and chronic hypoxia
    • Farber HW, Barnett HF: Differences in prostaglandin metabolism in cultured aortic and pulmonary arterial endothelial cells exposed to acute and chronic hypoxia. Circ Res 68:1446-57, 1991
    • (1991) Circ Res , vol.68 , pp. 1446-1457
    • Farber, H.W.1    Barnett, H.F.2
  • 90
    • 0026536299 scopus 로고
    • Acute hypoxia alters eicosanoid production of perfused pulmonary artery endothelial cells in culture
    • Martin LD, Barnes SD, Wetzel RC: Acute hypoxia alters eicosanoid production of perfused pulmonary artery endothelial cells in culture. Prostaglandins 43:371-82, 1992
    • (1992) Prostaglandins , vol.43 , pp. 371-382
    • Martin, L.D.1    Barnes, S.D.2    Wetzel, R.C.3
  • 91
    • 0023099831 scopus 로고
    • Sequential alterations in glomerular prostaglandin and thromboxane synthesis in diabetic rats: Relationship to the hyperfiltration of early diabetes
    • Craven PA, Caines MA, DeRubertis FR: Sequential alterations in glomerular prostaglandin and thromboxane synthesis in diabetic rats: relationship to the hyperfiltration of early diabetes. Metabolism 36:95-103, 1987
    • (1987) Metabolism , vol.36 , pp. 95-103
    • Craven, P.A.1    Caines, M.A.2    DeRubertis, F.R.3
  • 92
    • 0024386018 scopus 로고
    • Sorbinil suppresses glomerular prostaglandin production in the streptozotocin diabetic rat
    • Craven PA, DeRubertis FR: Sorbinil suppresses glomerular prostaglandin production in the streptozotocin diabetic rat. Metabolism 38:649-54, 1989
    • (1989) Metabolism , vol.38 , pp. 649-654
    • Craven, P.A.1    DeRubertis, F.R.2
  • 93
    • 0025877353 scopus 로고
    • The effect of aldose reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus
    • Chang WP, Dimitriadis E, Allen T, Dunlop ME, Cooper M, Larkins RG: The effect of aldose reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus. Diabetologia 34:225-31, 1991
    • (1991) Diabetologia , vol.34 , pp. 225-231
    • Chang, W.P.1    Dimitriadis, E.2    Allen, T.3    Dunlop, M.E.4    Cooper, M.5    Larkins, R.G.6
  • 95
    • 0025215946 scopus 로고
    • Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta
    • Tesfamariam B, Brown ML, Deykin D, Cohen RA: Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta. J Clin Invest 85:929-32, 1990
    • (1990) J Clin Invest , vol.85 , pp. 929-932
    • Tesfamariam, B.1    Brown, M.L.2    Deykin, D.3    Cohen, R.A.4
  • 96
    • 0023948928 scopus 로고
    • Role of enhanced arachidonate availability through phospholipase A2 pathway in mediation of increased prostaglandin synthesis by glomeruli from diabetic rats
    • Craven PA, Patterson MC, DeRubertis FR: Role of enhanced arachidonate availability through phospholipase A2 pathway in mediation of increased prostaglandin synthesis by glomeruli from diabetic rats. Diabetes 37:429-35, 1988
    • (1988) Diabetes , vol.37 , pp. 429-435
    • Craven, P.A.1    Patterson, M.C.2    Derubertis, F.R.3
  • 97
    • 0024565104 scopus 로고
    • Superoxide, iron, vascular endothelium and reperfusion injury
    • Halliwell B: Superoxide, iron, vascular endothelium and reperfusion injury. Free Radical Res Comms 5:315-18, 1989
    • (1989) Free Radical Res Comms , vol.5 , pp. 315-318
    • Halliwell, B.1
  • 98
    • 0025819503 scopus 로고
    • Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia
    • Lefer AM, Tsao PS, Lefer DJ, Ma X: Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia. FASEB J 5:2029-34, 1991
    • (1991) FASEB J , vol.5 , pp. 2029-2034
    • Lefer, A.M.1    Tsao, P.S.2    Lefer, D.J.3    Ma, X.4
  • 99
    • 0023270343 scopus 로고
    • The primary localization of free radical generation after anoxia/reoxygenation in isolated endothelial cells
    • Ratych RE, Chuknyiska RS, Bulkley GB: The primary localization of free radical generation after anoxia/reoxygenation in isolated endothelial cells. Surgery 102:122-31, 1987
    • (1987) Surgery , vol.102 , pp. 122-131
    • Ratych, R.E.1    Chuknyiska, R.S.2    Bulkley, G.B.3
  • 100
    • 0024440804 scopus 로고
    • Mechanism of hypoxic injury to pulmonary artery endothelial cell plasma membranes
    • Block ER, Patel JM, Edwards D: Mechanism of hypoxic injury to pulmonary artery endothelial cell plasma membranes. Am J Physiol 257:0223-31, 1989
    • (1989) Am J Physiol , vol.257 , pp. 223-231
    • Block, E.R.1    Patel, J.M.2    Edwards, D.3
  • 101
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan C: Nitric oxide as a secretory product of mammalian cells. FASEB J 6:3051-64, 1992
    • (1992) FASEB J , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 102
    • 0027104253 scopus 로고
    • Biochemistry of nitric oxide and its redox-activated forms
    • Stamler JS, Singel DJ, Loscalzo J: Biochemistry of nitric oxide and its redox-activated forms. Science 258:1898-1902, 1992
    • (1992) Science , vol.258 , pp. 1898-1902
    • Stamler, J.S.1    Singel, D.J.2    Loscalzo, J.3
  • 103
    • 0022884922 scopus 로고
    • PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH
    • Kukreja RC, Kontos HA, Hess ML, Ellis EF: PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH. Circ Res 59:612-19, 1986
    • (1986) Circ Res , vol.59 , pp. 612-619
    • Kukreja, R.C.1    Kontos, H.A.2    Hess, M.L.3    Ellis, E.F.4
  • 104
    • 0026759488 scopus 로고
    • Free radicals mediate endothelial cell dysfunction caused by elevated glucose
    • Tesfamariam B, Cohen RA: Free radicals mediate endothelial cell dysfunction caused by elevated glucose. Am J Physiol 263:H321-26, 1992
    • (1992) Am J Physiol , vol.263
    • Tesfamariam, B.1    Cohen, R.A.2
  • 105
    • 4243499352 scopus 로고
    • Antioxidant treatment prevents peripheral nerve dysfunction in diabetic rats
    • Cameron NE, Cotter MA, Maxfield E: Antioxidant treatment prevents peripheral nerve dysfunction in diabetic rats (Abstract). Diabetologia (Suppl. 1) 35:A150, 1992
    • (1992) Diabetologia (Suppl. 1) , vol.35
    • Cameron, N.E.1    Cotter, M.A.2    Maxfield, E.3
  • 108
    • 85034934049 scopus 로고    scopus 로고
    • Probucol prevents vascular protein leakage induced by diabetes, glucose, and glycated proteins
    • In press
    • Tilton RG, Chang K, Faller AM: Probucol prevents vascular protein leakage induced by diabetes, glucose, and glycated proteins (Abstract). Diabetes. In press
    • Diabetes
    • Tilton, R.G.1    Chang, K.2    Faller, A.M.3
  • 109
    • 0027409197 scopus 로고
    • Insulin stimulates the production and secretion of endothelin from bovine endothelial cells
    • Hu R-M, Levin ER, Pedram A, Frank HJL: Insulin stimulates the production and secretion of endothelin from bovine endothelial cells. Diabetes 42:351-58, 1993
    • (1993) Diabetes , vol.42 , pp. 351-358
    • Hu, R.-M.1    Levin, E.R.2    Pedram, A.3    Frank, H.J.L.4
  • 110
    • 0026539910 scopus 로고
    • Induction of resistance to endothelin-1's biochemical actions by elevated glucose levels in retinal pericytes
    • De La Rubia G, Oliver FJ, Inoguchi T, King GL: Induction of resistance to endothelin-1's biochemical actions by elevated glucose levels in retinal pericytes. Diabetes 41:1533-39, 1992
    • (1992) Diabetes , vol.41 , pp. 1533-1539
    • De La Rubia, G.1    Oliver, F.J.2    Inoguchi, T.3    King, G.L.4
  • 111
    • 0026322376 scopus 로고
    • Down-regulation of endothelin-1 receptors by protein kinase C in streptozotocin diabetic rats
    • Awazu M, Parker RE, Harvie BR, Ichikawa I, Kon V: Down-regulation of endothelin-1 receptors by protein kinase C in streptozotocin diabetic rats. J Cardiovasc Pharmacol 17 (Suppl. 7): S500-S502, 1991
    • (1991) J Cardiovasc Pharmacol , vol.17 , Issue.7 SUPPL.
    • Awazu, M.1    Parker, R.E.2    Harvie, B.R.3    Ichikawa, I.4    Kon, V.5
  • 112
    • 0017091041 scopus 로고
    • Mechanism for irreversible self-deactivation of prostaglandin synthetase
    • Egan RW, Paxton J, Kuehl FA Jr: Mechanism for irreversible self-deactivation of prostaglandin synthetase. J Biol Chem 251: 7329-35, 1976
    • (1976) J Biol Chem , vol.251 , pp. 7329-7335
    • Egan, R.W.1    Paxton, J.2    Kuehl Jr., F.A.3
  • 113
    • 0020535226 scopus 로고
    • Lipid peroxidation in relation to prostacyclin and thromboxane physiology and pathophysiology
    • Warso MA, Lands WEM: Lipid peroxidation in relation to prostacyclin and thromboxane physiology and pathophysiology. Br Med Bull 39:277-80, 1983
    • (1983) Br Med Bull , vol.39 , pp. 277-280
    • Warso, M.A.1    Lands, W.E.M.2
  • 114
    • 0026584898 scopus 로고
    • Nitric oxide, an inhibitor of lipid oxidation by lipoxygenase, cyclooxygenase and hemoglobin
    • Kanner J, Harel S, Granit R: Nitric oxide, an inhibitor of lipid oxidation by lipoxygenase, cyclooxygenase and hemoglobin. Lipids 27:46-49, 1992
    • (1992) Lipids , vol.27 , pp. 46-49
    • Kanner, J.1    Harel, S.2    Granit, R.3
  • 115
  • 116
    • 0024425516 scopus 로고
    • Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-α
    • Meier B, Radeke HH, Selle S, Younes M, Sies H, Resch K, Habermehl GG: Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-α. Biochem J 263:539-45, 1989
    • (1989) Biochem J , vol.263 , pp. 539-545
    • Meier, B.1    Radeke, H.H.2    Selle, S.3    Younes, M.4    Sies, H.5    Resch, K.6    Habermehl, G.G.7
  • 117
    • 0025642717 scopus 로고
    • Superoxide anion increases intracellular free calcium in human myometrial cells
    • Masumoto N, Tasaka K, Miyake A, Tanizawa O: Superoxide anion increases intracellular free calcium in human myometrial cells. J Biol Chem 265:22533-36, 1990
    • (1990) J Biol Chem , vol.265 , pp. 22533-22536
    • Masumoto, N.1    Tasaka, K.2    Miyake, A.3    Tanizawa, O.4
  • 118
    • 0025873514 scopus 로고
    • Superoxide anion increases intracellular pH, intracellular free calcium, and arachidonate release in human amnion cells
    • Ikebuchi Y, Masumoto N, Tasaka K, Koike K, Kasahara K: Superoxide anion increases intracellular pH, intracellular free calcium, and arachidonate release in human amnion cells. J Biol Chem 266:13233-37, 1991
    • (1991) J Biol Chem , vol.266 , pp. 13233-13237
    • Ikebuchi, Y.1    Masumoto, N.2    Tasaka, K.3    Koike, K.4    Kasahara, K.5
  • 119
    • 0025790241 scopus 로고
    • Phosphorylation by calcium calmodulin-dependent protein kinase II and protein kinase C modulates the activity of nitric oxide synthase
    • Nakane M, Mitchell J, Forstermann W, Murad F: Phosphorylation by calcium calmodulin-dependent protein kinase II and protein kinase C modulates the activity of nitric oxide synthase. Biochem Biophys Res Commun 180: 1396-1402, 1991
    • (1991) Biochem Biophys Res Commun , vol.180 , pp. 1396-1402
    • Nakane, M.1    Mitchell, J.2    Forstermann, W.3    Murad, F.4
  • 120
    • 0025802065 scopus 로고
    • Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase
    • Bredt DS, Hwang PM, Glatt CE, Lowenstein C, Reed RR, Snyder SH: Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature (Lond) 351:714-18, 1991
    • (1991) Nature (Lond) , vol.351 , pp. 714-718
    • Bredt, D.S.1    Hwang, P.M.2    Glatt, C.E.3    Lowenstein, C.4    Reed, R.R.5    Snyder, S.H.6
  • 121
    • 0023713429 scopus 로고
    • Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta
    • Pieper GM, Gross GJ: Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta. Am J Physiol 255:H825-33, 1988
    • (1988) Am J Physiol , vol.255
    • Pieper, G.M.1    Gross, G.J.2
  • 122
    • 0027089884 scopus 로고
    • Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes
    • Calver A, Collier J, Vallance P: Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes. J Clin Invest 90:2548-54, 1992
    • (1992) J Clin Invest , vol.90 , pp. 2548-2554
    • Calver, A.1    Collier, J.2    Vallance, P.3
  • 123
    • 0010228744 scopus 로고
    • Vascular responses in the forearm of microalbuminuric type I (insulin-dependent) diabetic patients: Evidence of altered nitric oxide biosynthesis
    • Elliott TG, Cockcroft JR, Groop PH, Earle K, Morocutti A, Viberti GC, Ritter JM: Vascular responses in the forearm of microalbuminuric type I (insulin-dependent) diabetic patients: evidence of altered nitric oxide biosynthesis (Abstract). Diabetologia 35 (Suppl. 1):A19, 1992
    • (1992) Diabetologia , vol.35 , Issue.1 SUPPL.
    • Elliott, T.G.1    Cockcroft, J.R.2    Groop, P.H.3    Earle, K.4    Morocutti, A.5    Viberti, G.C.6    Ritter, J.M.7
  • 124
    • 0027492051 scopus 로고
    • Endothelium-dependent vascular relaxation in patients with type I diabetes
    • Smits P, Kapma J, Jacobs M, Lutterman J, Thien T: Endothelium-dependent vascular relaxation in patients with type I diabetes. Diabetes 42:148-53, 1993
    • (1993) Diabetes , vol.42 , pp. 148-153
    • Smits, P.1    Kapma, J.2    Jacobs, M.3    Lutterman, J.4    Thien, T.5
  • 125
    • 0026584089 scopus 로고
    • 2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase
    • 2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J 281:627-30, 1992
    • (1992) Biochem J , vol.281 , pp. 627-630
    • Heinzel, B.1    John, M.2    Klatt, P.3    Böhme, E.4    Mayer, B.5
  • 127
    • 0026632656 scopus 로고
    • EDTA influences reactivity of isolated aorta from hypercholesterolemic rabbits
    • Simon BC, Cohen RA: EDTA influences reactivity of isolated aorta from hypercholesterolemic rabbits. Am J Physiol 262:H1606-10, 1992
    • (1992) Am J Physiol , vol.262
    • Simon, B.C.1    Cohen, R.A.2
  • 128
    • 0026062122 scopus 로고
    • Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes
    • Bucala R, Tracey KJ, Cerami A: Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes. J Clin Invest 87:432-38, 1991
    • (1991) J Clin Invest , vol.87 , pp. 432-438
    • Bucala, R.1    Tracey, K.J.2    Cerami, A.3
  • 129
    • 0024468325 scopus 로고
    • Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts: 1 role for lipid peroxidation?
    • Chojkier M, Houglum K, Solis-Herruzo J, Brenner DA: Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts: 1 role for lipid peroxidation? J Biol Chem 264:16957-62, 1989
    • (1989) J Biol Chem , vol.264 , pp. 16957-16962
    • Chojkier, M.1    Houglum, K.2    Solis-Herruzo, J.3    Brenner, D.A.4
  • 130
    • 0026317124 scopus 로고
    • Expression of genes related to the extracellular matrix in human endothelial cells: Differential modulation by elevated glucose concentrations, phorbol esters, and cAMP
    • Cagliero E, Roth T, Roy S, Maiello M, Lorenzi M: Expression of genes related to the extracellular matrix in human endothelial cells: differential modulation by elevated glucose concentrations, phorbol esters, and cAMP. J Biol Chem 266:14244-250, 1991
    • (1991) J Biol Chem , vol.266 , pp. 14244-14250
    • Cagliero, E.1    Roth, T.2    Roy, S.3    Maiello, M.4    Lorenzi, M.5
  • 131
    • 0026446032 scopus 로고
    • Biology of disease: Hyperglycemia and microangiopathy. Direct regulation by glucose of microvascular cells
    • Kreisberg JI: Biology of disease: hyperglycemia and microangiopathy. Direct regulation by glucose of microvascular cells. Lab Invest 67:416-26, 1992
    • (1992) Lab Invest , vol.67 , pp. 416-426
    • Kreisberg, J.I.1
  • 132
    • 0025322514 scopus 로고
    • Superoxide radical-mediated endothelial injury and vasoconstriction of rat thoracic aortic rings
    • Lawson DL, Mehta JL, Nichols WW, Mehta P, Donnelly WH: Superoxide radical-mediated endothelial injury and vasoconstriction of rat thoracic aortic rings. J Lab Clin Med 115:541-48, 1990
    • (1990) J Lab Clin Med , vol.115 , pp. 541-548
    • Lawson, D.L.1    Mehta, J.L.2    Nichols, W.W.3    Mehta, P.4    Donnelly, W.H.5
  • 133
    • 0025181994 scopus 로고
    • Activation of soluble guanylate cyclase by carbon monoxide and inhibition by superoxide anion
    • Brüne B, Schmidt K-U, Ullrich V: Activation of soluble guanylate cyclase by carbon monoxide and inhibition by superoxide anion. Eur J Biochem 192:683-88, 1990
    • (1990) Eur J Biochem , vol.192 , pp. 683-688
    • Brüne, B.1    Schmidt, K.-U.2    Ullrich, V.3
  • 134
    • 0009218873 scopus 로고
    • In human erythrocytes galactose induces greater imbalances in glycolysis than glucose
    • Frangos M, Santiago JV, Williamson JR: In human erythrocytes galactose induces greater imbalances in glycolysis than glucose (Abstract). Diabetes 40 (Suppl. 1):254A, 1991
    • (1991) Diabetes , vol.40 , Issue.1 SUPPL.
    • Frangos, M.1    Santiago, J.V.2    Williamson, J.R.3
  • 135
    • 0023885730 scopus 로고
    • Glutathione depletion in the lens of galactosemic and diabetic rats
    • Lou MF, Dickerson JE Jr, Garadi R, York BM Jr: Glutathione depletion in the lens of galactosemic and diabetic rats. Exp Eye Res 46:517-30, 1988
    • (1988) Exp Eye Res , vol.46 , pp. 517-530
    • Lou, M.F.1    Dickerson Jr., J.E.2    Garadi, R.3    York Jr., B.M.4
  • 136
    • 11944273854 scopus 로고
    • Antioxidant effects of calcium channel blockers against free radical injury in endothelial cells: Correlation of protection with preservation of glutathione levels
    • Mak IT, Boehme P, Weglicki WB: Antioxidant effects of calcium channel blockers against free radical injury in endothelial cells: correlation of protection with preservation of glutathione levels. Circ Res 70:1099-1103, 1992
    • (1992) Circ Res , vol.70 , pp. 1099-1103
    • Mak, I.T.1    Boehme, P.2    Weglicki, W.B.3
  • 137
    • 0023791398 scopus 로고
    • Non-enzymatic glycosylation (glycation) of lens proteins by galactose and protection by aspirin and reduced glutathione
    • Huby R, Harding JJ: Non-enzymatic glycosylation (glycation) of lens proteins by galactose and protection by aspirin and reduced glutathione. Exp Eye Res 47:53-59, 1988
    • (1988) Exp Eye Res , vol.47 , pp. 53-59
    • Huby, R.1    Harding, J.J.2
  • 138
    • 0025070983 scopus 로고
    • Non-tryptophan fluorescence and high molecular weight protein formation in lens crystalline of rats with chronic galactosemia: Prevention by the aldose reductase inhibitor sorbinil
    • Nagaraj RH, Monnier VM: Non-tryptophan fluorescence and high molecular weight protein formation in lens crystalline of rats with chronic galactosemia: prevention by the aldose reductase inhibitor sorbinil. Exp Eye Res 51:411-18, 1990
    • (1990) Exp Eye Res , vol.51 , pp. 411-418
    • Nagaraj, R.H.1    Monnier, V.M.2
  • 140
    • 0018817430 scopus 로고
    • Effect of alcohol intake on symptomatic peripheral neuropathy in diabetic men
    • McCulloch DK, Campbell IW, Prescott RJ, Clarke BF: Effect of alcohol intake on symptomatic peripheral neuropathy in diabetic men. Diabetes Care 3:245-47, 1980
    • (1980) Diabetes Care , vol.3 , pp. 245-247
    • McCulloch, D.K.1    Campbell, I.W.2    Prescott, R.J.3    Clarke, B.F.4
  • 142
    • 0025293777 scopus 로고
    • Hydrogen peroxide production during experimental protein glycation
    • Jiang ZY, Woollard ACS, Wolff SP: Hydrogen peroxide production during experimental protein glycation. FEBS Lett 268:69-71, 1990
    • (1990) FEBS Lett , vol.268 , pp. 69-71
    • Jiang, Z.Y.1    Woollard, A.C.S.2    Wolff, S.P.3
  • 143
    • 0025540553 scopus 로고
    • Free radical generation by early glycation products: A mechanism for accelerated atherogenesis in diabetes
    • Mullarkey CJ, Edelstein D, Brownlee M: Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem Biophys Res Commun 173:932-939, 1990
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 932-939
    • Mullarkey, C.J.1    Edelstein, D.2    Brownlee, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.