The predicted binding site and dynamics of peptide inhibitors to the methuselah GPCR from Drosophila melanogaster

Biochemistry

Volumn 47, Issue 48, 2008, Pages 12740-12749

  Heo, Jiyoung ^a   Ja, William W ^b   Benzer, Seymour ^b   Goddard III, William A ^a  

^a California Institute of Technology   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BINDING ENERGY; BIOCHEMISTRY; CRYSTAL STRUCTURE; FORECASTING; LIGANDS; PEPTIDES; PROTEINS; SURFACE PLASMON RESONANCE;

COUPLED RECEPTORS; DROSOPHILA MELANOGASTER; ECTODOMAIN; ELECTRON DENSITY MAPS; G PROTEINS; HIGH AFFINITIES; LIFE SPANS; LIGAND BINDINGS; LIGAND RECOGNITIONS; MUTANT PEPTIDES; PEPTIDE INHIBITORS; SURFACE PLASMONS;

BINDING SITES;

G PROTEIN COUPLED RECEPTOR; METHUSELAH INHIBITOR; PEPTIDE DERIVATIVE; PROTEIN METHUSELAH; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DROSOPHILA MELANOGASTER; MOLECULAR DYNAMICS; MOLECULAR MODEL; PREDICTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR BLOCKING;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; COMPUTATIONAL BIOLOGY; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ELECTRONS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; REPRODUCIBILITY OF RESULTS;

DROSOPHILA MELANOGASTER;

EID: 57049142684     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801335p     Document Type: Article

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